pyrroles has been researched along with netropsin in 49 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (59.18) | 18.7374 |
| 1990's | 9 (18.37) | 18.2507 |
| 2000's | 6 (12.24) | 29.6817 |
| 2010's | 3 (6.12) | 24.3611 |
| 2020's | 2 (4.08) | 2.80 |
| Authors | Studies |
|---|---|
| Martin, JC; O'Shea, DC; Wartell, RM | 1 |
| Grossman, LI; Hudspeth, ME; Johnson, PH; Tatti, KM | 1 |
| Nosikov, VV; Sain, B | 1 |
| Grokhovskiĭ, SL; Tsimmer, K; Tumanian, VG; Zasedatelev, AS; Zhuze, AL | 1 |
| Adnet, F; Liquier, J; Lown, JW; Rao, KE; Singh, MP; Taillandier, E | 1 |
| Beerman, TA; Gawron, LS; Lown, JW; Rao, KE; Sigmund, RD; Woynarowski, JM | 1 |
| Boyd, M; Denny, WA; Gravatt, GL; Lee, HH | 1 |
| Haaf, T; Hoehn, H; Kausch, K; Köhler, J; Poot, M | 1 |
| Grummt, F; Wegner, M | 1 |
| Bailly, C; Hénichart, JP | 1 |
| Dervan, PB | 1 |
| Balzarini, J; De Clercq, E; Krowicki, K; Lown, JW; Newman, RA | 1 |
| Brahmachari, SK; Choudhury, D; Ramesh, N; Rao, KE; Sasisekharan, V | 1 |
| Portugal, J; Waring, MJ | 2 |
| Breslauer, KJ; Chou, WY; Curry, J; Ferrante, R; Marky, LA; Remeta, DP; Snyder, JG; Zaunczkowski, D | 1 |
| Koch, MH; Michon, AM; Sayers, Z; Vega, MC | 1 |
| Dasgupta, D; Rao, KE; Sasisekharan, V | 1 |
| Fish, EL; Lane, MJ; Vournakis, JN | 1 |
| Dickerson, RE; Goodsell, D; Kopka, ML; Pjura, P; Yoon, C | 1 |
| Dervan, PB; Youngquist, RS | 1 |
| Manning, MC; Woody, RW | 1 |
| Balzarini, J; De Clercq, E; Krowicki, K; Lown, JW | 1 |
| Auble, DT; Bruzik, JP; deHaseth, PL | 1 |
| Rubin, J; Sundaralingam, M | 1 |
| Rønne, M; Thust, R | 1 |
| Guschlbauer, W; Luck, G; Marck, C; Schneider, C; Thiele, D; Zimmer, C | 1 |
| Becker, Y; Bialer, M; Mechoulam, R; Yagen, B | 2 |
| Crothers, DM; Dattagupta, N; Hogan, M | 1 |
| Bialer, M; El-On, J; Mechoulam, R; Yagen, B | 1 |
| Dervan, PB; Hertzberg, RP; Van Dyke, MW | 1 |
| Guschlbauer, W; Kakiuchi, N; Marck, C | 1 |
| Beabealashvili, RS; Gottikh, BP; Grokhovsky, SL; Gursky, GV; Khorlin, AA; Krylov, AS; Mikhailov, MV; Nikitin, SM; Retchinsky, VO; Streltsov, SA; Surovaya, AN; Zasedatelev, AS; Zhuze, AL | 1 |
| Lakhotia, SC; Roy, JK | 1 |
| Hartley, JA; Haskell, MK; Lee, M; McAdam, SR; Roldan, MC | 1 |
| Bartulewicz, D; Bielawski, K; Krajewska, D; Rózański, A | 1 |
| Bartulewicz, D; Markowska, A; Pućkowska, A; Rózański, A | 1 |
| Fishleigh, RV; Fox, KR; Khalaf, AI; Pitt, AR; Scobie, M; Suckling, CJ; Urwin, J; Waigh, RD; Young, SC | 1 |
| Denny, WA | 1 |
| Bruice, TW; Gonzalez, C; Moore, M; Ribeiro, S; Schmitz, U; Schroth, GP; Turin, L | 1 |
| Anthony, NG; Johnston, BF; Khalaf, AI; MacKay, SP; Parkinson, JA; Suckling, CJ; Waigh, RD | 1 |
| Baraldi, PG; Borgatti, M; Carrion, MD; Gambari, R; Heilmann, J; Iaconinoto, MA; Romagnoli, R; Tabrizi, MA | 1 |
| Baldeyrou, B; Benzschawel, K; David-Cordonnier, MH; Hildebrand, MP; Keuser, C; Lansiaux, A; Lemster, T; Pindur, U | 1 |
| Chee, GL; Guziec, FS; Guziec, LJ; Hasinoff, BB; Wu, X; Yalowich, JC; Zhang, R | 1 |
| Challis, GL; Demange, L; Galons, H; Lautru, S; Lombès, T; Pernodet, JL; Song, L | 1 |
| Deng, Z; Hao, C; Huang, S; Yu, Y; Zhao, C | 1 |
| Burkart, MD; Corpuz, JC; Davis, TD; Jaremko, MJ | 1 |
| Buchberger, A; Fahmi, NE; Henry, SJW; MacCulloch, T; Novacek, A; Simmons, CR; Stephanopoulos, N; Yan, H | 1 |
2 review(s) available for pyrroles and netropsin
| Article | Year |
|---|---|
DNA minor groove alkylating agents.
Topics: Alkylating Agents; Animals; Anthramycin; Antibiotics, Antineoplastic; Benzofurans; Bisbenzimidazole; Chlorambucil; Cyclohexanecarboxylic Acids; Cyclohexenes; Distamycins; DNA; Duocarmycins; Humans; Indoles; Netropsin; Nitrogen Mustard Compounds; Pyrroles; Structure-Activity Relationship | 2001 |
Type II non-ribosomal peptide synthetase proteins: structure, mechanism, and protein-protein interactions.
Topics: Amino Acids; Benzoic Acid; Cyclopropanes; Hydroxylation; Lactams; Macrolides; Netropsin; Peptide Synthases; Proline; Protein Interaction Maps; Pyrroles; Thiazoles; Thiones | 2020 |
47 other study(ies) available for pyrroles and netropsin
| Article | Year |
|---|---|
Conformational features of distamycin-DNA and netropsin-DNA complexes by Raman spectroscopy.
Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Distamycins; DNA; Guanidines; Netropsin; Nucleic Acid Conformation; Poly dA-dT; Polydeoxyribonucleotides; Pyrroles; Spectrum Analysis, Raman; Thymus Gland | 1978 |
Enhancement of buoyant separations between DNA's in preparative CsCl gradients containing distamycin A or netropsin.
Topics: Centrifugation, Density Gradient; Distamycins; DNA; Guanidines; Netropsin; Pyrroles; Species Specificity | 1978 |
Protection of particular endonuclease R. Hind III cleavage sites by distamycin A, propyl-distamycin and netropsin.
Topics: Deoxyribonucleotides; Distamycins; DNA Restriction Enzymes; DNA, Viral; Guanidines; Haemophilus; Molecular Weight; Netropsin; Pyrroles; Structure-Activity Relationship | 1977 |
[Stereochemical model of the molecular mechanism of the "recognition" of AT-pairs during the binding with DNA of the antibiotics distamycin A and netropsin].
Topics: Adenine; Anti-Bacterial Agents; Base Sequence; Distamycins; DNA; Guanidines; Models, Chemical; Netropsin; Pyrroles; Thymine | 1976 |
FTIR study of specific binding interactions between DNA minor groove binding ligands and polynucleotides.
Topics: Bisbenzimidazole; DNA; Fourier Analysis; Netropsin; Nucleic Acid Conformation; Polynucleotides; Pyrroles; Spectrophotometry, Infrared; Thiazoles | 1992 |
Netropsin and bis-netropsin analogs as inhibitors of the catalytic activity of mammalian DNA topoisomerase II and topoisomerase cleavable complexes.
Topics: Animals; Cell Line; Cell Nucleus; DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Kinetics; Macromolecular Substances; Mice; Netropsin; Pyrroles; Teniposide; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors | 1991 |
Pyrazole analogues of the bispyrrolecarboxamide anti-tumour antibiotics: synthesis, DNA binding and anti-tumour properties.
Topics: Amides; Animals; Antibiotics, Antineoplastic; Base Sequence; DNA, Neoplasm; Leukemia L1210; Leukemia P388; Molecular Sequence Data; Netropsin; Oligonucleotides; Poly dA-dT; Polydeoxyribonucleotides; Pyrroles; Tumor Cells, Cultured | 1991 |
The minor-groove binding DNA-ligands netropsin, distamycin A and berenil cause polyploidisation via impairment of the G2 phase of the cell cycle.
Topics: Amidines; Bisbenzimidazole; Bromodeoxyuridine; Diminazene; Distamycins; DNA; Fibroblasts; Flow Cytometry; Guanidines; Humans; In Vitro Techniques; Interphase; Netropsin; Polyploidy; Pyrroles | 1990 |
Netropsin, distamycin and berenil interact differentially with a high-affinity binding site for the high mobility group protein HMG-I.
Topics: Amidines; Antiprotozoal Agents; Base Sequence; Binding Sites; Deoxyribonuclease I; Diminazene; Distamycins; DNA; Guanidines; High Mobility Group Proteins; Molecular Sequence Data; Netropsin; Plasmids; Pyrroles | 1990 |
Subcellular distribution of a nitroxide spin-labeled netropsin-acridine hybrid in living KB cells: Electron Spin Resonance Study.
Topics: Acridines; Aminoacridines; Cell Nucleus; Cytoplasm; Electron Spin Resonance Spectroscopy; Guanidines; Humans; KB Cells; Kinetics; Netropsin; Pyrroles; Spin Labels; Time Factors | 1990 |
Design of sequence-specific DNA-binding molecules.
Topics: Base Sequence; Bisbenzimidazole; Dactinomycin; Distamycins; DNA; Edetic Acid; Iron; Models, Chemical; Netropsin; Organometallic Compounds; Pyrroles; Structure-Activity Relationship | 1986 |
Novel linked antiviral and antitumor agents related to netropsin and distamycin: synthesis and biological evaluation.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cell Survival; Cells, Cultured; Distamycins; DNA; Guanidines; Kidney; Microbial Sensitivity Tests; Molecular Structure; Netropsin; Pyrroles; Rabbits; Structure-Activity Relationship; Vaccinia virus; Viruses | 1989 |
Role of the environment in the interaction of nonintercalators with Z-DNA.
Topics: Chemical Phenomena; Chemistry; Chlorides; Cobalt; Distamycins; DNA; Ethanol; Guanidines; Ligands; Magnesium Chloride; Molecular Conformation; Netropsin; Polyamines; Polydeoxyribonucleotides; Pyrroles; Sodium Chloride; Spectrum Analysis | 1989 |
Hydroxyl radical footprinting of the sequence-selective binding of netropsin and distamycin to DNA.
Topics: Base Composition; Base Sequence; Binding Sites; Distamycins; DNA, Bacterial; Edetic Acid; Escherichia coli; Ferric Compounds; Guanidines; Hydroxides; Hydroxyl Radical; Molecular Sequence Data; Netropsin; Pyrroles | 1987 |
Enthalpy-entropy compensations in drug-DNA binding studies.
Topics: Calorimetry; Daunorubicin; Distamycins; DNA; DNA Damage; Ethidium; Guanidines; Intercalating Agents; Netropsin; Nucleic Acid Conformation; Poly dA-dT; Pyrroles; Salts; Thermodynamics | 1987 |
The superstructure of chromatin and its condensation mechanism. IV. Enzymatic digestion, thermal denaturation, effect of netropsin and distamycin.
Topics: Animals; Chickens; Chromatin; Distamycins; Erythrocytes; Guanidines; Hot Temperature; Micrococcal Nuclease; Netropsin; Pyrroles; X-Ray Diffraction; X-Rays | 1987 |
Interaction of synthetic analogues of distamycin and netropsin with nucleic acids. Does curvature of ligand play a role in distamycin-DNA interactions?
Topics: Circular Dichroism; Distamycins; DNA; Guanidines; Kinetics; Ligands; Netropsin; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Pyrroles | 1988 |
Determination of equilibrium binding affinity of distamycin and netropsin to the synthetic deoxyoligonucleotide sequence d(GGTATACC)2 by quantitative DNase I footprinting.
Topics: Binding Sites; Deoxyribonuclease I; Distamycins; DNA; Guanidines; Kinetics; Netropsin; Oligodeoxyribonucleotides; Pyrroles; Thermodynamics | 1988 |
The molecular origin of DNA-drug specificity in netropsin and distamycin.
Topics: Base Sequence; Distamycins; DNA; Guanidines; Models, Molecular; Netropsin; Nucleic Acid Conformation; Pyrroles; Structure-Activity Relationship; Thermodynamics; X-Ray Diffraction | 1985 |
Sequence-specific recognition of B-DNA by oligo(N-methylpyrrolecarboxamide)s.
Topics: Base Composition; Base Sequence; Binding Sites; Distamycins; DNA; Netropsin; Nucleic Acid Conformation; Pyrroles | 1985 |
Molecular orbital calculations on the oligopeptides netropsin, distamycin and related compounds.
Topics: Distamycins; Guanidines; Netropsin; Oligopeptides; Protein Conformation; Pyrroles; Structure-Activity Relationship | 1986 |
Structure-activity relationship of novel oligopeptide antiviral and antitumor agents related to netropsin and distamycin.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cell Line; Distamycins; Drug Evaluation, Preclinical; Guanidines; Humans; Indicators and Reagents; Leukemia L1210; Mice; Netropsin; Oligopeptides; Pyrroles; Structure-Activity Relationship; Vaccinia virus | 1986 |
Specific activation of transcription initiation by the sequence-specific DNA-binding agents distamycin A and netropsin.
Topics: Base Sequence; Distamycins; DNA-Directed RNA Polymerases; Escherichia coli; Genetic Variation; Guanidines; Kinetics; Netropsin; Promoter Regions, Genetic; Pyrroles; Transcription, Genetic | 1987 |
Comparison of binding sites in DNA for berenil, netropsin and distamycin. A footprinting study.
Topics: Amidines; Base Sequence; Binding Sites; Deoxyribonuclease I; Diminazene; Distamycins; DNA; Guanidines; Micrococcal Nuclease; Netropsin; Pyrroles | 1987 |
An unexpected major groove binding of netropsin and distamycin A to tRNA(phe).
Topics: Binding Sites; Distamycins; Guanidines; Models, Molecular; Molecular Structure; Netropsin; Nucleic Acid Conformation; Pyrroles; RNA, Fungal; RNA, Transfer, Amino Acid-Specific; RNA, Transfer, Phe; X-Ray Diffraction | 1984 |
Structural modifications induced in Chinese hamster V79--E chromosomes by prefixation treatment in vitro with the AT-specific agents netropsin, distamycin A, and Hoechst 33258.
Topics: Animals; Benzimidazoles; Bisbenzimidazole; Chromosomes; Cricetinae; Cricetulus; Distamycins; Guanidines; Netropsin; Pyrroles | 1981 |
Magnetic circular dichroism study of the binding of netropsin and distamycin A with DNA.
Topics: Circular Dichroism; Distamycins; DNA, Bacterial; Guanidines; Netropsin; Nucleic Acid Conformation; Pyrroles; Spectrophotometry, Ultraviolet | 1980 |
Structure-activity relationships of pyrrole amidine antiviral antibiotics. 2. Preparation of mono- and tripyrrole derivatives of congocidine.
Topics: Antiviral Agents; Cell Survival; DNA-Directed DNA Polymerase; DNA, Viral; Guanidines; In Vitro Techniques; Netropsin; Pyrroles; Simplexvirus; Structure-Activity Relationship; Virus Replication | 1980 |
Structure-activity relationships of pyrrole amidine antiviral antibiotics III: preparation of distamycin and congocidine derivatives based on 2,5-disubstituted pyrroles.
Topics: Antiviral Agents; Distamycins; Guanidines; Netropsin; Pyrroles; Structure-Activity Relationship | 1980 |
Interaction of netropsin and distamycin with deoxyribonucleic acid: electric dichroism study.
Topics: Animals; Binding Sites; Cattle; Distamycins; DNA; DNA, Bacterial; Electrochemistry; Guanidines; Netropsin; Nucleic Acid Conformation; Pyrroles; Spectrum Analysis; Thymus Gland | 1980 |
Antiparasitic structure-activity relationships of congocidine derivatives.
Topics: Animals; Antiparasitic Agents; Antiprotozoal Agents; Guanidines; Leishmaniasis; Male; Mice; Mice, Inbred BALB C; Netropsin; Pyrroles; Structure-Activity Relationship; Time Factors; Trypanocidal Agents | 1981 |
Map of distamycin, netropsin, and actinomycin binding sites on heterogeneous DNA: DNA cleavage-inhibition patterns with methidiumpropyl-EDTA.Fe(II).
Topics: Chemical Phenomena; Chemistry; Dactinomycin; Daunorubicin; Distamycins; DNA, Bacterial; Escherichia coli; Guanidines; Netropsin; Plasmids; Pyrroles; Structure-Activity Relationship | 1982 |
Specific interaction of netropsin, distamycin-3 and analogs with LC duplexes: reversion towards the B form of the 2'-deoxy-.2'-deoxy-2'-fluoro-hybrid duplexes upon specific interaction with netropsin, distamycin-3 and analogs.
Topics: Chemical Phenomena; Chemistry; Circular Dichroism; Distamycins; Guanidines; Netropsin; Poly I-C; Pyrroles; Structure-Activity Relationship | 1982 |
Synthetic sequence-specific ligands.
Topics: Amides; Base Sequence; Chemical Phenomena; Chemistry; Distamycins; DNA; Guanidines; Ligands; Models, Molecular; Netropsin; Oligopeptides; Polydeoxyribonucleotides; Pyrroles; Repressor Proteins; Structure-Activity Relationship; Transcription, Genetic | 1983 |
Effects of distamycin A & netropsin on condensation of mitotic chromosomes in early embryos & larval brain cells of Drosophila nasuta.
Topics: Animals; Brain; Chromosomes; Distamycins; Drosophila; Embryo, Nonmammalian; Female; Guanidines; Larva; Mitosis; Netropsin; Pyrroles | 1983 |
In vitro photoinduced cytotoxicity and DNA binding properties of psoralen and coumarin conjugates of netropsin analogues: DNA sequence-directed alkylation and cross-link formation.
Topics: Alkylation; Antineoplastic Agents; Base Composition; Coumarins; Cross-Linking Reagents; DNA; Ficusin; Furocoumarins; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Light; Molecular Structure; Netropsin; Photochemistry; Photochemotherapy; Pyrroles; Structure-Activity Relationship; Tumor Cells, Cultured | 1994 |
Synthetic analogues of netropsin and distamycin. II. Synthesis of a carbocyclic analogue of the pyrrolecarboxamide antitumour antibiotics.
Topics: Antiviral Agents; Benzene; Chemistry, Pharmaceutical; Chromatography, Thin Layer; Distamycins; Magnetic Resonance Spectroscopy; Molecular Structure; Netropsin; Pyrroles | 1995 |
Synthetic analogues of netropsin and distamycin. IV. Synthesis of a new carbocyclic analogue of distamycin with alkylating side groups.
Topics: Alkylating Agents; Alkylation; Anti-Bacterial Agents; Antiviral Agents; Benzene; Distamycins; Netropsin; Nitrobenzoates; Pyrroles | 1997 |
DNA binding, solubility, and partitioning characteristics of extended lexitropsins.
Topics: DNA; DNA Footprinting; Electrophoresis, Polyacrylamide Gel; Hydrogen Bonding; Hydrogen-Ion Concentration; Ligands; Netropsin; Pyrroles; Solubility | 2000 |
The hybridization-stabilization assay: a solution-based isothermal method for rapid screening and determination of sequence preference of ligands that bind to duplexed nucleic acids.
Topics: Base Pairing; Base Sequence; Binding, Competitive; Dactinomycin; Distamycins; DNA Footprinting; Drug Evaluation, Preclinical; Energy Transfer; Fluorescence; Intercalating Agents; Kinetics; Ligands; Netropsin; Nucleic Acid Hybridization; Nucleic Acids; Nylons; Oligonucleotides; Promoter Regions, Genetic; Pyrroles; Reproducibility of Results; Solutions; Substrate Specificity; Temperature; Thermodynamics | 2001 |
Short lexitropsin that recognizes the DNA minor groove at 5'-ACTAGT-3': understanding the role of isopropyl-thiazole.
Topics: DNA; Hydrogen; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Netropsin; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Pyrroles; Thiazoles | 2004 |
Synthesis and biological activity of alpha-bromoacryloyl lexitropsin conjugates.
Topics: Animals; Antineoplastic Agents, Alkylating; Benzofurans; Drug Screening Assays, Antitumor; Heterocyclic Compounds; Humans; Imidazoles; Mice; Molecular Structure; Netropsin; Pyrazoles; Pyrroles; Structure-Activity Relationship; Thiophenes; Tumor Cells, Cultured | 2005 |
Design, synthesis and biological evaluation of new oligopyrrole carboxamides linked with tricyclic DNA-intercalators as potential DNA ligands or topoisomerase inhibitors.
Topics: Antineoplastic Agents; Cell Line, Tumor; Distamycins; DNA; DNA Footprinting; Drug Design; Humans; Intercalating Agents; Ligands; Molecular Structure; Netropsin; Pyrroles; Structure-Activity Relationship; Topoisomerase Inhibitors | 2007 |
Design, synthesis and biological evaluation of a novel series of anthrapyrazoles linked with netropsin-like oligopyrrole carboxamides as anticancer agents.
Topics: Amides; Anthracyclines; Antineoplastic Agents; DNA; Drug Design; Humans; Intercalating Agents; K562 Cells; Netropsin; Pyrroles | 2010 |
A sweet origin for the key congocidine precursor 4-acetamidopyrrole-2-carboxylate.
Topics: Amides; Biological Products; Netropsin; Pyrroles; Streptomyces | 2012 |
Mining of the pyrrolamide antibiotics analogs in Streptomyces netropsis reveals the amidohydrolase-dependent "iterative strategy" underlying the pyrrole polymerization.
Topics: Amides; Amidohydrolases; Anti-Bacterial Agents; Biocatalysis; Biological Products; Distamycins; Multigene Family; Netropsin; Polymers; Pyrroles; Streptomyces; Tandem Mass Spectrometry | 2014 |
Site-Specific Arrangement and Structure Determination of Minor Groove Binding Molecules in Self-Assembled Three-Dimensional DNA Crystals.
Topics: DNA; Netropsin; Nucleic Acid Conformation; Nylons; Oligonucleotides; Pyrroles | 2023 |