pyrroles has been researched along with morphinans in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 7 (53.85) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Bella, DD | 1 |
| Farouz-Grant, F; Portoghese, PS | 1 |
| Aceto, MD; Breeden, S; Husbands, SM; Ko, MC; Lewis, JW; Neilan, CL; Traynor, JR; Woods, JH | 1 |
| Cadierno, V; Gimeno, J; Nebra, N | 1 |
| Divin, MF; Holden Ko, MC; Traynor, JR | 1 |
| Fujii, H; Hanamura, S; Hasebe, K; Ida, Y; Mochizuki, H; Nagase, H; Nakajima, M; Nakao, K; Nemoto, T; Osa, Y | 1 |
| Clark, MJ; Husbands, SM; Kumar, V; Lewis, JW; Traynor, JR | 1 |
| Balci, M; Basceken, S | 1 |
| Déméné, H; Granier, S; Huang, W; Kobilka, BK; Laeremans, T; Manglik, A; Mas, C; Sounier, R; Steyaert, J | 1 |
| Dror, RO; Feinberg, EN; Gmeiner, P; Granier, S; Huang, W; Husbands, SM; Kato, HE; Kling, RC; Kobilka, BK; Laeremans, T; Livingston, KE; Manglik, A; Sanborn, AL; Steyaert, J; Thorsen, TS; Traynor, JR; Venkatakrishnan, AJ; Weis, WI | 1 |
| Haeffner, F; Hoveyda, AH; Mikus, MS; Mszar, NW; Torker, S | 1 |
| Chan, YH; Wang, YT | 1 |
| Cong, X; Giorgetti, A; Sena, DM | 1 |
1 review(s) available for pyrroles and morphinans
| Article | Year |
|---|---|
Structural features associated with narcotics and narcotic antagonists.
Topics: Animals; Chemistry, Pharmaceutical; Ethanolamines; Mice; Molecular Conformation; Morphinans; Narcotic Antagonists; Narcotics; Pyrroles; Receptors, Drug; Stereoisomerism; Structure-Activity Relationship | 1975 |
12 other study(ies) available for pyrroles and morphinans
| Article | Year |
|---|---|
Pyrrolomorphinans as delta opioid receptor antagonists. The role of steric hindrance in conferring selectivity.
Topics: Animals; Electric Stimulation; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Guinea Pigs; Male; Mice; Models, Chemical; Morphinans; Morphine; Muscle, Smooth; Pyrroles; Receptors, Opioid, delta; Stereoisomerism | 1997 |
Characterization of the complex morphinan derivative BU72 as a high efficacy, long-lasting mu-opioid receptor agonist.
Topics: Analgesics; Animals; Binding, Competitive; Buprenorphine; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Female; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Ileum; In Vitro Techniques; Macaca mulatta; Male; Mice; Mice, Inbred ICR; Morphinans; Morphine; Muscle Contraction; Pain; Pain Measurement; Pyrroles; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sulfur Radioisotopes; Time Factors; Tritium; Vas Deferens | 2004 |
One-pot three-component catalytic synthesis of fully substituted pyrroles from readily available propargylic alcohols, 1,3-dicarbonyl compounds and primary amines.
Topics: Alcohols; Amines; Catalysis; Crystallography, X-Ray; Electrons; Imaging, Three-Dimensional; Magnetics; Models, Molecular; Molecular Structure; Morphinans; Pyrroles; Temperature | 2007 |
Comparison of the opioid receptor antagonist properties of naltrexone and 6 beta-naltrexol in morphine-naïve and morphine-dependent mice.
Topics: Animals; Binding, Competitive; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred ICR; Morphinans; Morphine; Morphine Dependence; Naltrexone; Narcotic Antagonists; Narcotics; Pain Measurement; Pyrroles; Receptors, Opioid, mu; Substance Withdrawal Syndrome | 2008 |
Synthesis of pyrrolomorphinan derivatives as kappa opioid agonists.
Topics: Morphinans; Pyrroles; Receptors, Opioid, kappa; Structure-Activity Relationship | 2010 |
Pyrrolo- and pyridomorphinans: non-selective opioid antagonists and delta opioid agonists/mu opioid partial agonists.
Topics: Analgesics, Opioid; Animals; CHO Cells; Cricetinae; Cricetulus; Humans; Kinetics; Morphinans; Protein Binding; Pyridines; Pyrroles; Receptors, Opioid, delta; Receptors, Opioid, mu; Structure-Activity Relationship | 2014 |
Design of pyrazolo-pyrrolo-pyrazines and pyrazolo-pyrrolo-diazepines via AuCl₃-catalyzed and NaH-supported cyclization of N-propargyl pyrazoles.
Topics: Azepines; Catalysis; Cyclization; Gold Compounds; Molecular Structure; Morphinans; Pyrazines; Pyrazoles; Pyrroles | 2015 |
Propagation of conformational changes during μ-opioid receptor activation.
Topics: Allosteric Regulation; Animals; Binding Sites; Heterotrimeric GTP-Binding Proteins; Lysine; Mice; Models, Molecular; Morphinans; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Conformation; Pyrroles; Receptors, Adrenergic, beta-2; Receptors, Opioid, mu; Single-Chain Antibodies; Structure-Activity Relationship; Substrate Specificity | 2015 |
Structural insights into µ-opioid receptor activation.
Topics: Allosteric Regulation; Animals; Binding Sites; Crystallography, X-Ray; Heterotrimeric GTP-Binding Proteins; Mice; Models, Molecular; Molecular Dynamics Simulation; Morphinans; Protein Stability; Protein Structure, Tertiary; Pyrroles; Receptor, Muscarinic M2; Receptors, Adrenergic, beta-2; Receptors, Opioid, mu; Single-Chain Antibodies; Structure-Activity Relationship | 2015 |
Electronically Activated Organoboron Catalysts for Enantioselective Propargyl Addition to Trifluoromethyl Ketones.
Topics: Arthritis, Rheumatoid; Benzamides; Boron Compounds; Catalysis; Electronics; Ketones; Molecular Structure; Morphinans; Pyridines; Pyrroles; Stereoisomerism | 2017 |
Understanding the molecular basis of agonist/antagonist mechanism of human mu opioid receptor through gaussian accelerated molecular dynamics method.
Topics: Amino Acid Motifs; Catalytic Domain; Humans; Models, Molecular; Molecular Dynamics Simulation; Morphinans; Naltrexone; Normal Distribution; Protein Binding; Protein Conformation; Pyrroles; Receptors, Opioid, mu | 2017 |
Ligand based conformational space studies of the μ-opioid receptor.
Topics: Amino Acids; Apoproteins; Binding Sites; Humans; Ligands; Lipid Bilayers; Molecular Docking Simulation; Molecular Dynamics Simulation; Morphinans; Morphine; Naloxone; Phosphatidylcholines; Protein Binding; Protein Conformation, alpha-Helical; Pyrroles; Receptors, Opioid, mu; Solutions; Water | 2021 |