pyrroles has been researched along with midazolam in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (27.78) | 29.6817 |
| 2010's | 9 (50.00) | 24.3611 |
| 2020's | 4 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Danielsen, P; Deacon, CF; Holst, JJ; Klarskov, L; Olesen, M | 1 |
| Harte, S; Mc Donnell, CG; O'Driscoll, J; O'Loughlin, C; Shorten, GD; Van Pelt, FD; Van Pelt, FN | 1 |
| Mc Donnell, CG; Shorten, G; Van Pelt, FN | 1 |
| Grime, K; Riley, RJ; Webborn, PJ | 1 |
| Inui, N; Kagawa, Y; Kokudai, M; Sakaeda, T; Takeuchi, K; Watanabe, H | 1 |
| Inagaki, H; Kiyokawa, Y; Mori, Y; Takeuchi, Y | 1 |
| Baker, SD; Chen, Z; den Hartigh, J; den Hollander, M; Gelderblom, H; Guchelaar, HJ; König-Quartel, JM; Ploeger, BA; van Erp, NP; Zandvliet, AS | 1 |
| Aohara, F; Fujimura, Y; Harakawa, N; Hasegawa, R; Katori, N; Kim, SR; Maekawa, K; Naito, M; Niwa, T; Okuda, H; Sai, K; Saito, Y; Sawada, J; Tohkin, M; Yoshimura, T | 1 |
| Akiyama, Y; Fujita, K; Murayama, N; Sasaki, Y; Sugiyama, M; Yamazaki, H | 1 |
| Azuma, Y; Fujita, T; Haruyama, Y; Ikeda, Y; Kumagai, Y; Maeda, K; Sugiyama, Y; Yamane, N; Yoshida, K | 1 |
| Bi, YA; El-Kattan, AF; Fenner, KS; Iseki, K; Kimoto, E; Lai, Y; Linder, C; Walsky, R; Whalen, KM; Xiao, Y; Yang, YS; Zhang, H | 1 |
| Alvey, C; Dowty, ME; Fahmi, OA; Gupta, P; Krishnaswami, S; Riese, RJ; Walsky, RL; Wang, R | 1 |
| de Wit, D; den Hartigh, J; den Hollander, M; Gelderblom, H; Guchelaar, HJ; Hessing, T; König-Quartel, JM; Sparreboom, A; van Erp, NP | 1 |
| Balakrishnar, B; Bennink, RJ; Daali, Y; Eechoute, K; Gurney, H; Huitema, AD; Kam, BL; Kloth, JS; Klümpen, HJ; Mathijssen, RH; Samer, CF; Schellens, JH; Wong, M; Yu, H; Zwinderman, AH | 1 |
| Fischer, T; Inoue, SI; Ishizuka, T; Rozehnal, V; Sugiyama, D; Yamada, M | 1 |
| Furuie, H; Igawa, Y; Ishizuka, H; Ishizuka, T; Kato, M; Kuroda, K; Nishikawa, Y; Okuda, Y; Shimizu, T; Toyama, K | 1 |
| Alizadeh, N; Nakhodchi, S | 1 |
| Beelen, A; Curd, L; Goti, V; Horton, JK; Li, C; Sale, M; Tao, W | 1 |
6 trial(s) available for pyrroles and midazolam
| Article | Year |
|---|---|
Effects of statins on the pharmacokinetics of midazolam in healthy volunteers.
Topics: Adult; Area Under Curve; Atorvastatin; Cross-Over Studies; Cytochrome P-450 CYP3A; Drug Interactions; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypnotics and Sedatives; Japan; Male; Midazolam; Pyrroles; Quinolines; Simvastatin | 2009 |
Marginal increase of sunitinib exposure by grapefruit juice.
Topics: Adult; Aged; Antineoplastic Agents; Area Under Curve; Beverages; Biological Availability; Citrus paradisi; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Labeling; Female; Food-Drug Interactions; Humans; Indoles; Male; Midazolam; Middle Aged; Neoplasms; Pyrroles; Sunitinib | 2011 |
Identification of the rate-determining process in the hepatic clearance of atorvastatin in a clinical cassette microdosing study.
Topics: Adult; Atorvastatin; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Heptanoic Acids; Humans; Liver; Male; Metabolic Clearance Rate; Midazolam; Organic Anion Transporters; Pravastatin; Pyrroles; Time Factors; Young Adult | 2011 |
Lack of effect of tofacitinib (CP-690,550) on the pharmacokinetics of the CYP3A4 substrate midazolam in healthy volunteers: confirmation of in vitro data.
Topics: Adult; Cross-Over Studies; Cytochrome P-450 CYP3A; Drug Interactions; Female; GABA Modulators; Half-Life; Humans; Janus Kinases; Male; Metabolic Clearance Rate; Midazolam; Middle Aged; Piperidines; Pyrimidines; Pyrroles; Young Adult | 2012 |
Effects of Repeated Oral Administration of Esaxerenone on the Pharmacokinetics of Midazolam in Healthy Japanese Males.
Topics: Administration, Oral; Adult; Area Under Curve; Asian People; Cytochrome P-450 CYP3A; Drug Interactions; Half-Life; Humans; Hypnotics and Sedatives; Male; Midazolam; Mineralocorticoid Receptor Antagonists; Pyrroles; Sulfones; Young Adult | 2021 |
Pharmacokinetic Drug-Drug Interaction Studies Between Trilaciclib and Midazolam, Metformin, Rifampin, Itraconazole, and Topotecan in Healthy Volunteers and Patients with Extensive-Stage Small-Cell Lung Cancer.
Topics: Area Under Curve; Drug Interactions; Healthy Volunteers; Humans; Itraconazole; Lung Neoplasms; Metformin; Midazolam; Prospective Studies; Pyrimidines; Pyrroles; Rifampin; Topotecan | 2022 |
12 other study(ies) available for pyrroles and midazolam
| Article | Year |
|---|---|
Dipeptidyl peptidase IV inhibition reduces the degradation and clearance of GIP and potentiates its insulinotropic and antihyperglycemic effects in anesthetized pigs.
Topics: Anesthesia; Animals; Blood Glucose; Chromatography, High Pressure Liquid; Dipeptidyl Peptidase 4; Enzyme Inhibitors; Gastric Inhibitory Polypeptide; Insulin; Ketamine; Midazolam; Pyrroles; Radioimmunoassay; Swine; Valine | 2001 |
The effects of concurrent atorvastatin therapy on the pharmacokinetics of intravenous midazolam.
Topics: Aged; Anesthesia, General; Anesthetics, Intravenous; Anticholesteremic Agents; Atorvastatin; Drug Interactions; Female; Half-Life; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Matched-Pair Analysis; Midazolam; Middle Aged; Pyrroles | 2003 |
Effect of atorvastatin and fluvastatin on the metabolism of midazolam by cytochrome P450 in vitro.
Topics: Atorvastatin; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypnotics and Sedatives; In Vitro Techniques; Indoles; Microsomes, Liver; Midazolam; Pyrroles | 2005 |
Functional consequences of active hepatic uptake on cytochrome P450 inhibition in rat and human hepatocytes.
Topics: Animals; Atorvastatin; Cells, Cultured; Culture Media; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diclofenac; Enzyme Inhibitors; Estrone; Hepatocytes; Heptanoic Acids; Humans; Hydroxylation; Liver; Midazolam; Pyrroles; Quinolines; Rats; Recombinant Proteins; Tritium | 2008 |
The alarm pheromone in male rats as a unique anxiety model: psychopharmacological evidence using anxiolytics.
Topics: Administration, Inhalation; Animals; Anti-Anxiety Agents; Anxiety; Buspirone; Clonidine; Disease Models, Animal; Male; Midazolam; Phenelzine; Pheromones; Propranolol; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Reflex, Startle | 2010 |
CYP3A4*16 and CYP3A4*18 alleles found in East Asians exhibit differential catalytic activities for seven CYP3A4 substrate drugs.
Topics: Alleles; Animals; Asia, Eastern; Atorvastatin; Biocatalysis; Camptothecin; Carbamazepine; Cytochrome P-450 CYP3A; Docetaxel; Heptanoic Acids; Humans; Irinotecan; Midazolam; Models, Molecular; Paclitaxel; Pyrroles; Spodoptera; Substrate Specificity; Taxoids; Terfenadine | 2010 |
Sorafenib and sunitinib, two anticancer drugs, inhibit CYP3A4-mediated and activate CY3A5-mediated midazolam 1'-hydroxylation.
Topics: Antineoplastic Agents; Benzenesulfonates; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Humans; Hydroxylation; Indoles; Liver; Microsomes, Liver; Midazolam; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrroles; Sorafenib; Sunitinib | 2011 |
Differential modulation of cytochrome P450 activity and the effect of 1-aminobenzotriazole on hepatic transport in sandwich-cultured human hepatocytes.
Topics: Anti-Anxiety Agents; Anticholesteremic Agents; Atorvastatin; Bile; Biological Transport; Cell Survival; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fluorobenzenes; Hepatocytes; Heptanoic Acids; Humans; Isoenzymes; Midazolam; Models, Biological; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Sulfonamides; Time Factors; Triazoles | 2012 |
Midazolam as a phenotyping probe to predict sunitinib exposure in patients with cancer.
Topics: Adult; Aged; Antineoplastic Agents; Area Under Curve; Cytochrome P-450 CYP3A; Female; Humans; Indoles; Male; Midazolam; Middle Aged; Neoplasms; Phenotype; Prospective Studies; Pyrroles; Sunitinib | 2014 |
Predictive value of CYP3A and ABCB1 phenotyping probes for the pharmacokinetics of sunitinib: the ClearSun study.
Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Biotransformation; Cytochrome P-450 CYP3A; Female; Humans; Hypnotics and Sedatives; Indoles; Male; Midazolam; Middle Aged; Phenotype; Prospective Studies; Pyrroles; Radiopharmaceuticals; Sunitinib; Technetium Tc 99m Sestamibi | 2014 |
Drug-Drug Interaction Risk Assessment of Esaxerenone as a Perpetrator by In Vitro Studies and Static and Physiologically Based Pharmacokinetic Models.
Topics: Administration, Oral; Area Under Curve; Computer Simulation; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Glucuronosyltransferase; Humans; Hypertension; Intestinal Mucosa; Japan; Liver; Male; Microsomes, Liver; Midazolam; Mineralocorticoid Receptor Antagonists; Models, Biological; Pyrroles; Risk Assessment; Sulfones | 2020 |
Rapid simultaneous determination of ketamine and midazolam in biological samples using ion mobility spectrometry combined by headspace solid-phase microextraction.
Topics: Humans; Ion Mobility Spectrometry; Ketamine; Midazolam; Polymers; Pyrroles; Reproducibility of Results; Solid Phase Microextraction | 2021 |