pyrroles has been researched along with ketoconazole in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 6 (42.86) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Da Rocha-Pitta, I; De Lima, JG; Higino, JS; Lins-Galdino, S; Luu-Duc, C | 1 |
| Assang, C; Baillie, TA; Lin, JH; Lu, P; Ma, B; Meng, Y; Prueksaritanont, T; Reider, PJ; Tang, C | 1 |
| Clampitt, DM; Goeders, NE | 1 |
| Chu, FM; Gong, AS; Guo, ZR; Sun, YM; Xu, HY; Zhang, P; Zhong, DF | 1 |
| Goeders, NE; Moffett, MC | 1 |
| Bizot, MN; Camenisch, G; Dieterich, HA; Dole, WP; Howard, D; Reynolds, C; Schuetz, H; Vaidyanathan, S; Yeh, CM | 1 |
| Ando, H; Araki, N; Enosawa, S; Fujimura, A; Hasegawa, G; Nagai, H; Omasa, T; Tsuruoka, S; Wang, N; Yanagihara, H | 1 |
| Chandler, PA; Huang, HL; Kovarik, JM; Sfikas, N; Slade, A | 1 |
| Bodmer, M; Brecht, K; Bur, D; Krähenbühl, S; Tsakiris, DA; Zahno, A | 1 |
| Ahlers, CM; Christopher, LJ; Has, T; Kurland, JF; Masson, E; Roongta, V; Shen, G; Vakkalagadda, B; Yang, Z; Zhang, S | 1 |
| Chang, JH; Cheong, J; Ly, J; Messick, K; Plise, E; Wright, M; Zhang, X | 1 |
| Chee, EL; Fernandez-Lastra, C; Lim, AY; Modamio, P; Segarra, I | 1 |
| Chen, Y; Guo, X; Li, Q; Li, W; Peng, Y; Zhao, G; Zheng, J | 1 |
2 trial(s) available for pyrroles and ketoconazole
| Article | Year |
|---|---|
Atorvastatin--a new lipid-lowering drug.
Topics: Anti-Bacterial Agents; Anticholesteremic Agents; Antifungal Agents; Atorvastatin; Dose-Response Relationship, Drug; Drug Interactions; Erythromycin; Heptanoic Acids; Humans; Hypercholesterolemia; Hyperlipidemias; Ketoconazole; Pyrroles | 1997 |
Pharmacokinetics of the oral direct renin inhibitor aliskiren in combination with digoxin, atorvastatin, and ketoconazole in healthy subjects: the role of P-glycoprotein in the disposition of aliskiren.
Topics: Adult; Amides; Animals; Antifungal Agents; Atorvastatin; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cell Line; Cytochrome P-450 CYP3A; Digoxin; Drug Interactions; Female; Fumarates; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ketoconazole; Male; Organic Anion Transporters; Pyrroles; Renin; Tissue Distribution; Young Adult | 2008 |
12 other study(ies) available for pyrroles and ketoconazole
| Article | Year |
|---|---|
5-benzylidene pyrrolones. IV--Synthesis and antifungal activity of some 5-benzylidene derivatives of 1,2-dimethyl-3-carbethoxy-pyrrol-4-one.
Topics: Antifungal Agents; Benzylidene Compounds; Chemical Phenomena; Chemistry, Physical; Ketoconazole; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Neurospora crassa; Pyrroles | 1990 |
Metabolic interactions between mibefradil and HMG-CoA reductase inhibitors: an in vitro investigation with human liver preparations.
Topics: Aryl Hydrocarbon Hydroxylases; Atorvastatin; Benzimidazoles; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Ketoconazole; Kinetics; Lovastatin; Mibefradil; Microsomes, Liver; Oxidoreductases, N-Demethylating; Pyridines; Pyrroles; Simvastatin; Tetrahydronaphthalenes | 1999 |
Potential role for the hypothalamo-pituitary-adrenal axis in the conditioned reinforcer-induced reinstatement of extinguished cocaine seeking in rats.
Topics: Analysis of Variance; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corticosterone; Extinction, Psychological; Hypothalamo-Hypophyseal System; Ketoconazole; Male; Pituitary-Adrenal System; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Reinforcement Schedule; Reinforcement, Psychology; Self Administration; Stress, Psychological | 2002 |
Formation of 4'-carboxyl acid metabolite of imrecoxib by rat liver microsomes.
Topics: Animals; Biotransformation; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dexamethasone; Ketoconazole; Male; Microsomes, Liver; NADP; Pyrroles; Rats; Rats, Wistar; Sulfides | 2006 |
CP-154,526, a CRF type-1 receptor antagonist, attenuates the cue-and methamphetamine-induced reinstatement of extinguished methamphetamine-seeking behavior in rats.
Topics: Amphetamine-Related Disorders; Animals; Corticotropin-Releasing Hormone; Cues; Dose-Response Relationship, Drug; Extinction, Psychological; Hypothalamo-Hypophyseal System; Infusions, Intravenous; Injections, Intraperitoneal; Injections, Intraventricular; Ketoconazole; Male; Methamphetamine; Motivation; Pituitary-Adrenal System; Premedication; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Self Administration | 2007 |
Human CYP3A4-introduced HepG2 cells: in vitro screening system of new chemicals for the evaluation of CYP3A4-inhibiting activity.
Topics: Ammonia; Animals; Atorvastatin; Cell Line, Tumor; Cricetinae; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Evaluation, Preclinical; Enzyme Inhibitors; Glutamate-Ammonia Ligase; Heptanoic Acids; Humans; Ketoconazole; Lidocaine; Nifedipine; Pyrroles | 2008 |
The effect on sotrastaurin pharmacokinetics of strong CYP3A inhibition by ketoconazole.
Topics: Administration, Oral; Adult; Antifungal Agents; Area Under Curve; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Half-Life; Humans; Immunosuppressive Agents; Ketoconazole; Male; Pyrroles; Quinazolines; Young Adult | 2009 |
Effects of drug interactions on biotransformation and antiplatelet effect of clopidogrel in vitro.
Topics: Aryl Hydrocarbon Hydroxylases; Atorvastatin; Clarithromycin; Clopidogrel; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Enzyme Inhibitors; Heptanoic Acids; Humans; In Vitro Techniques; Ketoconazole; Microsomes, Liver; Models, Molecular; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Pyrroles; Recombinant Proteins; Simvastatin; Substrate Specificity; Ticlopidine | 2010 |
Inhibitory effect of ketoconazole on the pharmacokinetics of a multireceptor tyrosine kinase inhibitor BMS-690514 in healthy participants: assessing the mechanism of the interaction with physiologically-based pharmacokinetic simulations.
Topics: Adult; Antifungal Agents; Antineoplastic Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Computer Simulation; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Genotype; Humans; Ketoconazole; Male; Middle Aged; Models, Biological; Piperidines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrroles; Triazines; Young Adult | 2013 |
Differential effects of Rifampin and Ketoconazole on the blood and liver concentration of atorvastatin in wild-type and Cyp3a and Oatp1a/b knockout mice.
Topics: Animals; Atorvastatin; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Female; HEK293 Cells; Heptanoic Acids; Humans; Ketoconazole; Liver; Mice; Mice, Knockout; Organic Anion Transport Protein 1; Pyrroles; Rifampin | 2014 |
Sunitinib tissue distribution changes after coadministration with ketoconazole in mice.
Topics: Animals; Antifungal Agents; Area Under Curve; Drug Interactions; Female; Half-Life; Indoles; Ketoconazole; Mice; Mice, Inbred ICR; Protein Kinase Inhibitors; Pyrroles; Sunitinib; Tissue Distribution | 2016 |
Tofacitinib Is a Mechanism-Based Inactivator of Cytochrome P450 3A4.
Topics: Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Enzyme Assays; Humans; Ketoconazole; Male; Microsomes, Liver; NADP; Piperidines; Pyrimidines; Pyrroles | 2019 |