pyrroles has been researched along with interleukin-8 in 47 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (8.51) | 18.2507 |
| 2000's | 20 (42.55) | 29.6817 |
| 2010's | 23 (48.94) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, JC; White, JR | 1 |
| Breton, JJ; Chabot-Fletcher, MC | 1 |
| Chabot-Fletcher, M; Jackson, JR; Marshall, LA; Roshak, A | 1 |
| Breton, JJ; Chabot-Fletcher, M | 1 |
| Friedland, JS; Shaw, TC; Thomas, LH | 1 |
| Baker, CH; Buchdunger, E; Cohen, P; Fidler, IJ; Killion, JJ; Solorzano, CC; Traxler, P; Tsan, R | 1 |
| Aparicio, C; Blanco-Colio, LM; Díaz, C; Egido, J; Gerique, JG; Gómez-Hernández, A; Hernández, G; Hernández-Presa, MA; Hernández-Vargas, P; Martín-Ventura, JL; Mas, S; Ortega, L; Ortego, M; Tuñón, J; Vivanco, F | 1 |
| Fidler, IJ; Karashima, T; Killion, JJ; Kim, SJ; Shepherd, DL; Uehara, H | 1 |
| Goldenring, JR; Gupta, S; Hammond, CE; Smolka, AJ | 1 |
| Kimura, T; Shimada, K; Ushiyama, S; Wada, Y | 1 |
| Aukrust, P; Boullier, A; Damås, JK; Green, S; Quehenberger, O; Sandberg, WJ; Smith, C; Waehre, T | 1 |
| Dulak, J; Jazwa, A; Jozkowicz, A; Loboda, A; Molema, G | 1 |
| Arant, CB; Chegini, N; Debella, AE; Luo, X; Schofield, RS; Welder, GJ; Wessel, TR; Zineh, I | 1 |
| Fimmel, S; Glass, E; Krause, K; Schnitger, A; Zouboulis, CC | 1 |
| Chan, IH; Chan, W; Cheng, KK; Fung, JW; Kong, SL; Lam, CW; Lam, L; Lee, SW; Lin, H; Sanderson, JE; Yu, CM; Zhang, Q | 1 |
| Canalli, AA; Conran, N; Costa, FF; Franco-Penteado, CF; Saad, ST; Traina, F | 1 |
| Amato, M; Arquati, M; Baldassarre, D; Brusoni, B; Camera, M; Cortellaro, M; Fiorentini, C; Montorsi, P; Porta, B; Romano, S; Tremoli, E | 1 |
| Aukrust, P; Breland, UM; Damås, JK; Fevang, B; Frøland, SS; Gullestad, L; Halvorsen, B; Oie, E; Otterdal, K; Sandberg, WJ; Smith, C; Waehre, T; Yndestad, A | 1 |
| Hashizume, H; Kamio, N; Matsushima, K; Nakao, S; Sugiya, H | 1 |
| Catalano, M; Cipriani, R; Eusebi, F; Lauro, C; Limatola, C; Sobrero, F; Trettel, F | 1 |
| Rouabhia, M; Shi, G; Zhang, Z | 1 |
| Kabeya, T; Katou, Y; Kikuchi, H; Kurata, S; Oshima, Y; Sekiya, M; Ueda, K | 1 |
| Ho, CM; Liao, W; Wei, F; Wong, DT; Xu, Z; Yang, Y | 1 |
| Castelli, P; Castiglioni, L; Consuelo Maio, R; Cosentino, M; De Leo, A; Guasti, L; Lecchini, S; Legnaro, M; Marino, F; Maroni, L; Piffaretti, G; Rasini, E; Schembri, L; Tozzi, M; Venco, A | 1 |
| Ding, Y; Furge, KA; Futreal, PA; Huang, D; Kahnoski, R; Petillo, D; Qian, CN; Rini, BI; Teh, BT; Zhou, M | 1 |
| Aoki, K; Doi, H; Kagari, T; Nagasaki, T; Nakao, A; Ohkawa, N; Shimozato, T; Ushiyama, S | 1 |
| Ameur, N; Bidart, JM; Broutin, S; Caillou, B; Dupuy, C; Lacroix, L; Oumata, N; Petit, B; Robert, T; Schlumberger, M; Talbot, M | 1 |
| Aguilar, G; Albanell, J; Bellmunt, J; Calvo, A; Carles, J; Castellano, D; Gallardo, E; González-Larriba, JL; Maroto, P; Mellado, B; Perez-Gracia, JL; Prior, C; Villanueva, X | 1 |
| Chen, X; Hara, M; Ikeda, S; Kamijo, S; Kawasaki, J; Ogawa, H; Okumura, K; Takai, T; Ushio, H; Vu, AT; Xie, Y | 1 |
| Heymach, JV; Mateo, J; Zurita, AJ | 1 |
| Gibbs, S; Niessen, FB; Scheper, RJ; van den Broek, LJ | 1 |
| Cucinotta, M; Oteri, R; Teti, D; Venza, I; Venza, M; Visalli, M | 1 |
| Arnaboldi, L; Baetta, R; Bellosta, S; Bonomo, A; Corsini, A; Ferri, N; Granata, A; Miglietta, D; Oliva, F; Ongini, E | 1 |
| Ping, D; Qin, X; Xiao, H; Zuo, K | 1 |
| Eilles, C; Grimm, D; Grosse, J; Infanger, M; Magnusson, NE; Pohl, F; Warnke, E; Wehland, M | 1 |
| DePrimo, SE; Eisen, T; Figlin, RA; Harmon, CS; Huang, X; Hudes, GR; Hutson, TE; Kim, ST; Michaelson, MD; Motzer, RJ; Négrier, S; Williams, JA | 1 |
| Deng, GH; Jiang, Y; Liu, J; Peng, XC; Wang, Y; Wei, YQ; Zhang, J | 1 |
| Choi, YJ; Chun, HG; Chung, HC; Chung, IJ; Han, SW; Kim, JG; Kim, SY; Kim, TW; Kim, YH; Lee, J; Shin, DB; Shin, SJ; Song, HS | 1 |
| Coin, F; Ieguchi, K; Kato, Y; Kikuchi, H; Kurata, S; Maru, Y; Oshima, Y; Tomita, T | 1 |
| Deng, GH; Deng, YT; He, SS; Jiang, Y; Liu, J; Luo, XM; Mao, YY; Peng, XC; Wang, Y; Wei, YQ; Xia, XY; Zhang, J | 1 |
| Bing, N; Choueiri, TK; Davis, ID; Deen, KC; Esteban, E; Garcia-Donas, J; Johnson, T; McCann, L; Motzer, RJ; Pandite, LN; Rodríguez-Antona, C; Spraggs, CF; Sternberg, CN; Whittaker, JC; Xu, CF; Xue, Z | 1 |
| Aungier, SR; Cartwright, AJ; Ito, K; Midwood, KS; To, WS | 1 |
| Boven, E; Castellano, D; Diekstra, MH; García-Donas, J; Gelderblom, H; Guchelaar, HJ; Liu, X; Mathijssen, RH; Rini, BI; Rodríguez-Antona, C; Swen, JJ | 1 |
| Chen, BC; Lin, CH; Shih, CH | 1 |
| Mitchell, TS; Moots, RJ; Wright, HL | 1 |
| Bergmann, L; Diekstra, MH; Fritsch, A; Gauler, T; Guchelaar, HJ; Hauser, S; Houtsma, D; Jaehde, U; Kanefendt, F; Kiemeney, LA; Kinzig, M; Moes, D; Moritz, B; Mross, K; Oosterwijk, E; Roessler, M; Schindele, D; Sörgel, F; Stelzer, C; Swen, JJ | 1 |
| Jia, J; Li, W; Liao, W; Liu, W; Ou, F; Su, K; Sun, J; Sun, Y; Zhang, Z; Zheng, Y | 1 |
1 review(s) available for pyrroles and interleukin-8
| Article | Year |
|---|---|
Circulating biomarkers of response to sunitinib in gastroenteropancreatic neuroendocrine tumors: current data and clinical outlook.
Topics: Antineoplastic Agents; Biomarkers, Pharmacological; Biomarkers, Tumor; Everolimus; Gastrointestinal Neoplasms; Humans; Indoles; Interleukin-8; Molecular Targeted Therapy; Neuroendocrine Tumors; Pancreatic Neoplasms; Protein Kinase Inhibitors; Pyrroles; Sirolimus; Sunitinib; TOR Serine-Threonine Kinases; Vascular Endothelial Growth Factor A | 2012 |
6 trial(s) available for pyrroles and interleukin-8
| Article | Year |
|---|---|
Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, is elevated in coronary artery disease and is reduced during statin therapy.
Topics: Angina, Unstable; Atorvastatin; Cell Adhesion; Cells, Cultured; Chemokine CX3CL1; Chemokines, CX3C; Chemotaxis; Cholesterol, LDL; Coronary Artery Disease; CX3C Chemokine Receptor 1; Endothelium, Vascular; Gene Expression; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-8; Leukocytes, Mononuclear; Membrane Proteins; Myocardial Infarction; Pyrroles; Receptors, Chemokine; Simvastatin; Umbilical Veins | 2005 |
Comparison of intensive and low-dose atorvastatin therapy in the reduction of carotid intimal-medial thickness in patients with coronary heart disease.
Topics: Aged; Atorvastatin; C-Reactive Protein; Carotid Arteries; Carotid Artery Diseases; Coronary Disease; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-18; Interleukin-6; Interleukin-8; Lipids; Male; Middle Aged; Pyrroles; Tumor Necrosis Factor-alpha; Tunica Intima; Tunica Media | 2007 |
Phase II study of sunitinib as first-line treatment of urothelial cancer patients ineligible to receive cisplatin-based chemotherapy: baseline interleukin-8 and tumor contrast enhancement as potential predictive factors of activity.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Transitional Cell; Cisplatin; Contrast Media; Disease-Free Survival; Female; Humans; Indoles; Interleukin-8; Kaplan-Meier Estimate; Male; Pyrroles; Sunitinib; Tomography, X-Ray Computed; Treatment Outcome; Urologic Neoplasms | 2011 |
Circulating proteins as potential biomarkers of sunitinib and interferon-α efficacy in treatment-naïve patients with metastatic renal cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Renal Cell; Female; Humans; Indoles; Interferon-alpha; Interleukin-8; Kidney Neoplasms; Male; Middle Aged; Proportional Hazards Models; Pyrroles; Sunitinib; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-3 | 2014 |
A phase II open-label randomized multicenter trial of TSU-68 in combination with S-1 and oxaliplatin versus S-1 in combination with oxaliplatin in patients with metastatic colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Becaplermin; C-Reactive Protein; Colorectal Neoplasms; Disease-Free Survival; Drug Combinations; Female; Humans; Indoles; Interleukin-6; Interleukin-8; L-Lactate Dehydrogenase; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Oxindoles; Oxonic Acid; Platelet-Derived Growth Factor; Propionates; Proto-Oncogene Proteins c-sis; Pyrroles; Tegafur; Vascular Cell Adhesion Molecule-1; Vascular Endothelial Growth Factor A | 2014 |
Population Modeling Integrating Pharmacokinetics, Pharmacodynamics, Pharmacogenetics, and Clinical Outcome in Patients With Sunitinib-Treated Cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Carcinoma, Renal Cell; Colorectal Neoplasms; Cytochrome P-450 CYP3A; Female; Genotype; Humans; Indoles; Interleukin-8; Kidney Neoplasms; Male; Middle Aged; Models, Biological; Polymorphism, Single Nucleotide; Protein Kinase Inhibitors; Pyrroles; Sunitinib; Treatment Outcome; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Vascular Endothelial Growth Factor Receptor-3 | 2017 |
40 other study(ies) available for pyrroles and interleukin-8
| Article | Year |
|---|---|
Effect of protein kinase inhibitors on IL-8/NAP-1 release from human umbilical vein endothelial cells.
Topics: Alkaloids; Benzoquinones; Carbazoles; Cells, Cultured; Endothelium, Vascular; Humans; Indoles; Interleukin-1; Interleukin-8; Lactams, Macrocyclic; Protein Kinase Inhibitors; Pyrroles; Quinones; Recombinant Proteins; Rifabutin; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Umbilical Veins | 1993 |
The natural product hymenialdisine inhibits interleukin-8 production in U937 cells by inhibition of nuclear factor-kappaB.
Topics: Azepines; Humans; Interleukin-8; Luciferases; NF-kappa B; Proto-Oncogene Proteins; Pyrroles; RNA, Messenger; Transcription Factor RelB; Transcription Factors; Tumor Cells, Cultured | 1997 |
Inhibition of NFkappaB-mediated interleukin-1beta-stimulated prostaglandin E2 formation by the marine natural product hymenialdisine.
Topics: Adult; Arthritis, Rheumatoid; Azepines; Cells, Cultured; Dinoprostone; Endothelial Growth Factors; Humans; Interleukin-1; Interleukin-8; Lymphokines; NF-kappa B; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; Pyrroles; Synovial Membrane; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1997 |
Effect of staurosporine on transcription factor NF-kappaB in human keratinocytes.
Topics: Base Sequence; Cells, Cultured; Enzyme Inhibitors; Genes, Reporter; Humans; Indoles; Interleukin-8; Keratinocytes; Luciferases; NF-kappa B; Protein Kinase C; Proto-Oncogene Proteins; Pyrroles; RNA, Messenger; Staurosporine; Transcription Factor RelB; Transcription Factors | 1998 |
Regulation of IL-10 secretion after phagocytosis of Mycobacterium tuberculosis by human monocytic cells.
Topics: Carbazoles; Cell Line; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Genistein; Humans; Indoles; Interleukin-10; Interleukin-8; Mycobacterium tuberculosis; Naphthalenes; Phagocytosis; Protein Kinase C; Protein-Tyrosine Kinases; Pyrroles | 2000 |
Optimization for the blockade of epidermal growth factor receptor signaling for therapy of human pancreatic carcinoma.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Cell Division; Deoxycytidine; Drug Administration Schedule; Drug Therapy, Combination; Endothelial Growth Factors; Enzyme Inhibitors; ErbB Receptors; Gemcitabine; Humans; Immunohistochemistry; Interleukin-8; Lymphokines; Male; Mice; Mice, Nude; Neoplasm Metastasis; Pancreatic Neoplasms; Phosphorylation; Platelet Endothelial Cell Adhesion Molecule-1; Proliferating Cell Nuclear Antigen; Pyrimidines; Pyrroles; Ribonucleotide Reductases; Signal Transduction; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Xenograft Model Antitumor Assays | 2001 |
Atorvastatin reduces the expression of cyclooxygenase-2 in a rabbit model of atherosclerosis and in cultured vascular smooth muscle cells.
Topics: Animals; Arteriosclerosis; Atorvastatin; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Disease Models, Animal; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-8; Isoenzymes; Lipids; Macrophages; Male; Matrix Metalloproteinases; Muscle, Smooth, Vascular; NF-kappa B; Prostaglandin-Endoperoxide Synthases; Protein Isoforms; Pyrroles; Rabbits; Random Allocation; Randomized Controlled Trials as Topic; Time Factors | 2002 |
Blockade of epidermal growth factor receptor signaling in tumor cells and tumor-associated endothelial cells for therapy of androgen-independent human prostate cancer growing in the bone of nude mice.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Blotting, Western; Bone and Bones; Bone Neoplasms; Dose-Response Relationship, Drug; Endothelial Growth Factors; Endothelium, Vascular; ErbB Receptors; Fibroblast Growth Factor 2; Immunohistochemistry; In Situ Nick-End Labeling; Intercellular Signaling Peptides and Proteins; Interleukin-8; Lymphokines; Male; Mice; Mice, Nude; Microscopy, Fluorescence; Neoplasm Metastasis; Neoplasm Transplantation; Paclitaxel; Phosphorylation; Platelet Endothelial Cell Adhesion Molecule-1; Proliferating Cell Nuclear Antigen; Prostatic Neoplasms; Pyrimidines; Pyrroles; Signal Transduction; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2003 |
Inhibition of gastric H,K-ATPase activity and gastric epithelial cell IL-8 secretion by the pyrrolizine derivative ML 3000.
Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Enzyme Inhibitors; Gastric Mucosa; Humans; Hydrochloric Acid; Interleukin-1; Interleukin-8; Omeprazole; Parietal Cells, Gastric; Proton Pump Inhibitors; Pyrroles; Rabbits | 2004 |
Novel p38 MAP kinase inhibitor R-130823 suppresses IL-6, IL-8 and MMP-13 production in spheroid culture of human synovial sarcoma cell line SW 982.
Topics: Cell Adhesion; Cell Culture Techniques; Cell Line, Tumor; Dinoprostone; Humans; Interleukin-6; Interleukin-8; Matrix Metalloproteinase 13; Matrix Metalloproteinase Inhibitors; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Pyrroles; Sarcoma, Synovial; Spheroids, Cellular | 2005 |
Angiogenic transcriptome of human microvascular endothelial cells: Effect of hypoxia, modulation by atorvastatin.
Topics: Atorvastatin; Cell Hypoxia; Cell Line; Dose-Response Relationship, Drug; Endothelial Cells; Gene Expression Profiling; Gene Expression Regulation; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-8; Oligonucleotide Array Sequence Analysis; Placenta Growth Factor; Pregnancy Proteins; Promoter Regions, Genetic; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thrombospondin 1; Transcription, Genetic; Vascular Endothelial Growth Factor A | 2006 |
Modulatory effects of atorvastatin on endothelial cell-derived chemokines, cytokines, and angiogenic factors.
Topics: Atorvastatin; Cells, Cultured; Chemokine CCL2; Chemokine CXCL5; Chemokines, CXC; Endothelial Cells; Fibroblast Growth Factors; Granulocyte Colony-Stimulating Factor; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunologic Factors; Interleukin-6; Interleukin-8; Mevalonic Acid; Pyrroles | 2006 |
Corticotropin-releasing hormone skin signaling is receptor-mediated and is predominant in the sebaceous glands.
Topics: Amphibian Proteins; Carrier Proteins; Cell Proliferation; Cell Survival; Corticotropin-Releasing Hormone; Interleukin-1; Interleukin-6; Interleukin-8; Peptide Hormones; Peptides; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Sebaceous Glands; Signal Transduction; Skin; Skin Physiological Phenomena; Urocortins; Urotensins | 2007 |
Role for cAMP-protein kinase A signalling in augmented neutrophil adhesion and chemotaxis in sickle cell disease.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Antisickling Agents; Carbazoles; Cell Adhesion; Chemotaxis; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Female; Fibronectins; Humans; Hydroxyurea; Indoles; Interleukin-8; Male; Middle Aged; Neutrophils; Pyrroles; Signal Transduction | 2007 |
E-selectin and TFPI are associated with carotid intima-media thickness in stable IHD patients: the baseline findings of the MIAMI study.
Topics: Atorvastatin; Biomarkers; C-Reactive Protein; Carotid Artery Diseases; Cholesterol; E-Selectin; Endothelium, Vascular; Female; Fibrinogen; Heptanoic Acids; Humans; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-6; Interleukin-8; Lipoproteins; Male; Middle Aged; Prospective Studies; Pyrroles; Thromboplastin; Triglycerides; Tumor Necrosis Factor-alpha; Tunica Intima; Vascular Cell Adhesion Molecule-1; von Willebrand Factor | 2008 |
High levels and inflammatory effects of soluble CXC ligand 16 (CXCL16) in coronary artery disease: down-regulatory effects of statins.
Topics: Aged; Atorvastatin; Case-Control Studies; Cells, Cultured; Chemokine CCL2; Chemokine CXCL16; Chemokines, CXC; Coronary Artery Disease; Down-Regulation; Endothelium, Vascular; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-8; Leukocytes, Mononuclear; Male; Middle Aged; Muscle, Smooth, Vascular; Pyrroles; Receptors, Scavenger; Simvastatin | 2008 |
Plasmin is involved in inflammation via protease-activated receptor-1 activation in human dental pulp.
Topics: Adult; Calcium; Cells, Cultured; Dental Pulp; Dinoprostone; Fibrinolysin; Humans; Inflammation; Interleukin-8; Peptides; Pyrroles; Quinazolines; Receptor, PAR-1; RNA, Messenger | 2008 |
Chemokine CXCL8 modulates GluR1 phosphorylation.
Topics: Animals; Animals, Newborn; Calcium; Carbazoles; Cells, Cultured; Cerebellum; Chelating Agents; Chemotaxis; Cyclic AMP; Egtazic Acid; Enzyme Inhibitors; Gene Expression Regulation; Hippocampus; Humans; Interleukin-8; Mutation; Neurons; Phosphorylation; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Time Factors; Transfection | 2008 |
The regulation of cell functions electrically using biodegradable polypyrrole-polylactide conductors.
Topics: Biocompatible Materials; Cell Adhesion; Cell Culture Techniques; Cells, Cultured; Coated Materials, Biocompatible; Electric Conductivity; Electric Stimulation; Fibroblasts; Humans; Interleukin-6; Interleukin-8; Materials Testing; Polyesters; Polymers; Pyrroles | 2008 |
Revised structure and synthesis of celastramycin a, a potent innate immune suppressor.
Topics: Animals; Drosophila; Endothelial Cells; Humans; Immunity, Innate; Immunosuppressive Agents; Interleukin-8; Pyrroles; Resorcinols; Tumor Necrosis Factor-alpha; Umbilical Veins | 2009 |
Bio/abiotic interface constructed from nanoscale DNA dendrimer and conducting polymer for ultrasensitive biomolecular diagnosis.
Topics: Biosensing Techniques; Dendrimers; DNA; Electric Conductivity; Electrochemistry; Electrodes; Humans; Interleukin-1beta; Interleukin-8; Nanostructures; Polymers; Pyrroles; Surface Properties | 2009 |
Angiotensin type 1 receptor expression and interleukin-8 production in polymorphonuclear leukocytes of patients with peripheral arterial disease.
Topics: Aged; Aged, 80 and over; Anticholesteremic Agents; Apolipoproteins A; Apolipoproteins B; Atherosclerosis; Atorvastatin; Cardiovascular Diseases; Case-Control Studies; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Endarterectomy; Female; Femoral Artery; Gene Expression; Heptanoic Acids; Humans; Interleukin-8; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peripheral Vascular Diseases; Pyrroles; Receptor, Angiotensin, Type 1; Triglycerides | 2009 |
Interleukin-8 mediates resistance to antiangiogenic agent sunitinib in renal cell carcinoma.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Neutralizing; Carcinoma, Renal Cell; Cell Line, Tumor; Drug Resistance, Neoplasm; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation, Neoplastic; Humans; Indoles; Interleukin-8; Kidney Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Pyrroles; Sunitinib; Xenograft Model Antitumor Assays | 2010 |
Tetrahydropyridine derivatives with inhibitory activity on the production of proinflammatory cytokines: part 3.
Topics: Animals; Antirheumatic Agents; Arthritis, Experimental; Cytokines; Humans; Indolizines; Interleukin-1beta; Interleukin-6; Interleukin-8; Mice; Pyridines; Pyrroles; Rats; Structure-Activity Relationship; Tumor Necrosis Factor-alpha | 2010 |
Identification of soluble candidate biomarkers of therapeutic response to sunitinib in medullary thyroid carcinoma in preclinical models.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Biomarkers, Tumor; Carcinoembryonic Antigen; Carcinoma, Medullary; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Hyaluronan Receptors; Indoles; Interleukin-8; Mice; Mice, Nude; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Mas; Proto-Oncogene Proteins c-ret; Pyrroles; RNA Interference; Sunitinib; Tenascin; Thyroid Neoplasms; Transforming Growth Factor beta2; Tumor Burden; Xenograft Model Antitumor Assays | 2011 |
Extracellular double-stranded RNA induces TSLP via an endosomal acidification- and NF-κB-dependent pathway in human keratinocytes.
Topics: Cells, Cultured; Cytokines; Endosomes; Humans; Indoles; Interferon Regulatory Factor-3; Interferon-beta; Interleukin-8; Keratinocytes; Macrolides; NF-kappa B; Oxindoles; Poly I-C; Propionates; Pyrroles; RNA, Double-Stranded; RNA, Small Interfering; Signal Transduction; Thymic Stromal Lymphopoietin; Toll-Like Receptor 3; Transcription Factor RelA | 2011 |
Development, validation and testing of a human tissue engineered hypertrophic scar model.
Topics: Animal Testing Alternatives; Atorvastatin; Cell Proliferation; Cicatrix, Hypertrophic; Gene Expression Regulation; Hazardous Substances; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-6; Interleukin-8; Mesenchymal Stem Cells; Models, Biological; Pyrroles; Reproducibility of Results; Skin; Tissue Engineering | 2012 |
Class II-specific histone deacetylase inhibitors MC1568 and MC1575 suppress IL-8 expression in human melanoma cells.
Topics: Acetylation; Cell Line, Tumor; Cell Proliferation; DNA-Directed RNA Polymerases; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Interleukin-8; Melanoma; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-jun; Pyrroles; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factor TFIIB; Transcription, Genetic; Uveal Neoplasms | 2013 |
Nitric oxide-donating atorvastatin attenuates neutrophil recruitment during vascular inflammation independent of changes in plasma cholesterol.
Topics: Acute Disease; Animals; Atherosclerosis; Atorvastatin; Carotid Arteries; Cell Survival; Chemotaxis, Leukocyte; Cholesterol; Heptanoic Acids; Human Umbilical Vein Endothelial Cells; Humans; Interleukin-8; Male; Molecular Structure; Monocytes; Neutrophil Infiltration; Neutrophils; Nitric Oxide Donors; Pyrroles; Rabbits | 2013 |
Inhibition of Rho and Rac geranylgeranylation by atorvastatin is critical for preservation of endothelial junction integrity.
Topics: Antigens, CD; Atorvastatin; Cadherins; cdc42 GTP-Binding Protein; Guanosine Triphosphate; Heptanoic Acids; Human Umbilical Vein Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intercellular Junctions; Interleukin-6; Interleukin-8; Lipopolysaccharides; Mevalonic Acid; Polyisoprenyl Phosphates; Prenylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Pyrroles; rho-Associated Kinases; Sesquiterpenes; Thrombin | 2013 |
Impact of sunitinib on human thyroid cancer cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cytokines; Humans; Indoles; Interleukin-6; Interleukin-8; Protein Kinase Inhibitors; Pyrroles; Radiation, Ionizing; RNA, Messenger; Sunitinib; Thyroid Neoplasms; Tumor Necrosis Factor-alpha; Up-Regulation; Vascular Endothelial Growth Factor D; Vascular Endothelial Growth Factor Receptor-2 | 2013 |
Exogenous norepinephrine attenuates the efficacy of sunitinib in a mouse cancer model.
Topics: Adrenergic alpha-Agonists; Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Indoles; Inhibitory Concentration 50; Interleukin-6; Interleukin-8; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Norepinephrine; Propranolol; Pyrroles; Receptors, Adrenergic, beta; Signal Transduction; Sunitinib; Tumor Burden; Vascular Endothelial Growth Factor A | 2014 |
ZFC3H1, a zinc finger protein, modulates IL-8 transcription by binding with celastramycin A, a potential immune suppressor.
Topics: Cell Line, Tumor; DNA-Binding Proteins; Endonucleases; Gene Expression; HeLa Cells; Humans; Interleukin-8; Phosphoproteins; Protein Binding; Pyrroles; Resorcinols; RNA Interference; RNA Stability; RNA, Small Interfering; Signal Transduction; Transcription Factors; Transcriptional Activation; Tumor Necrosis Factor-alpha; Ultraviolet Rays | 2014 |
The effect of chronic stress on anti-angiogenesis of sunitinib in colorectal cancer models.
Topics: Adrenergic alpha-Agonists; Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Chronic Disease; Colorectal Neoplasms; Disease Models, Animal; Female; Humans; Indoles; Interleukin-8; Mice; Mice, Inbred BALB C; Norepinephrine; Pyrroles; Receptors, Adrenergic, beta; Signal Transduction; Stress, Psychological; Sunitinib; Vascular Endothelial Growth Factor A | 2015 |
IL8 polymorphisms and overall survival in pazopanib- or sunitinib-treated patients with renal cell carcinoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Antineoplastic Agents; Carcinoma, Renal Cell; Clinical Trials, Phase III as Topic; Female; Humans; Indazoles; Indoles; Interleukin-8; Kidney Neoplasms; Male; Middle Aged; Polymorphism, Single Nucleotide; Pyrimidines; Pyrroles; Randomized Controlled Trials as Topic; Sulfonamides; Sunitinib; Survival Analysis; Young Adult | 2015 |
Potent anti-inflammatory effects of the narrow spectrum kinase inhibitor RV1088 on rheumatoid arthritis synovial membrane cells.
Topics: Acetamides; Adalimumab; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Dasatinib; Dose-Response Relationship, Drug; Humans; Inflammation Mediators; Interleukin-6; Interleukin-8; Macrophages; Monocytes; Naphthalenes; Oxazines; Piperidines; Primary Cell Culture; Protein Kinase Inhibitors; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; RNA, Small Interfering; Signal Transduction; Synovial Membrane; Tumor Necrosis Factor-alpha; Urea | 2015 |
Association of single nucleotide polymorphisms in IL8 and IL13 with sunitinib-induced toxicity in patients with metastatic renal cell carcinoma.
Topics: Aged; Alleles; Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Indoles; Interleukin-13; Interleukin-8; Kidney Neoplasms; Logistic Models; Male; Middle Aged; Neoplasm Metastasis; Polymorphism, Single Nucleotide; Pyrroles; Sunitinib; Survival Rate | 2015 |
Thrombin-induced IL-8/CXCL8 release is mediated by CK2, MSK1, and NF-κB pathways in human lung epithelial cells.
Topics: Animals; Apigenin; Casein Kinase II; Cells, Cultured; Epithelial Cells; Humans; Indoles; Interleukin-8; Lung; NF-kappa B; Phosphorylation; Pyrroles; Ribosomal Protein S6 Kinases, 90-kDa; RNA, Small Interfering; Signal Transduction; Thrombin; Transcription Factor RelA; Triazoles | 2015 |
Janus kinase inhibitors prevent migration of rheumatoid arthritis neutrophils towards interleukin-8, but do not inhibit priming of the respiratory burst or reactive oxygen species production.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Azetidines; Case-Control Studies; Cell Movement; Cells, Cultured; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-8; Janus Kinases; Male; Middle Aged; Neutrophils; Piperidines; Protein Kinase Inhibitors; Purines; Pyrazoles; Pyrimidines; Pyrroles; Reactive Oxygen Species; Respiratory Burst; Sulfonamides; Tetradecanoylphorbol Acetate; United Kingdom | 2017 |
HDAC10 upregulation contributes to interleukin 1β-mediated inflammatory activation of synovium-derived mesenchymal stem cells in temporomandibular joint.
Topics: Arthritis, Rheumatoid; Cells, Cultured; Fibroblasts; Histone Deacetylases; Humans; Hydroxamic Acids; Interleukin-1beta; Interleukin-8; Mesenchymal Stem Cells; NF-kappa B; Osteoarthritis; Pyrroles; Signal Transduction; Synovial Membrane; Synoviocytes; Temporomandibular Joint; Transcriptional Activation; Up-Regulation | 2019 |