pyrroles has been researched along with incb039110 in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 11 (91.67) | 2.80 |
| Authors | Studies |
|---|---|
| Warren, RB; Yiu, ZZ | 1 |
| Barbour, AM; Chen, X; Darpo, B; Epstein, N; Gong, X; He, K; Landman, R; Punwani, N; Xue, H; Yeleswaram, S | 1 |
| Barbour, AM; Chen, X; Epstein, N; Marbury, T; Petusky, S; Punwani, N; Srinivas, N; Xun, Z; Yeleswaram, S; Yuska, B; Zhou, G | 1 |
| Barbour, AM; Chen, X; Cimino, E; Epstein, N; Leonetti-Whalen, C; Punwani, N; Rockich, K; Yeleswaram, S; Zhou, G | 1 |
| Chang, Y; Chen, J; Christiano, AM; Dai, Z | 1 |
| Avci, AB; Burmester, GR; Feist, E | 1 |
| Abhyankar, S; Arbushites, M; Barbour, AM; Chacon, MJ; Chen, YB; Clausen, J; Deeren, D; Ghosh, M; Giebel, S; Kwon, M; Lakshminarayanan, M; Meyers, G; Morariu-Zamfir, R; Sanz, J; Schroeder, MA; Socié, G; Vaz, CP; Volodin, L; Zeiser, R | 1 |
| Asatiani, E; Berenson, JR; Bordoni, R; Cook, RJ; Edenfield, WJ; Mohan, S; Savona, MR; Srinivas, N; Zeidan, AM; Zhou, G | 1 |
| Berlin, JD; Ding, K; Garrido-Laguna, I; Geschwindt, R; Leopold, L; LoRusso, PM; Luke, JJ; Mansfield, AS; Messersmith, WA; Naing, A; Nemunaitis, JJ; Powderly, JD; Sahebjam, S; Smith, M | 1 |
| Austin-Tse, C; Bryson, B; Chen, YB; Fortune, SM; Hughes, T; Lareau, CA; Ludwig, LS; Massoth, LR; Peters, JM; Regev, A; Rehm, HL; Rosenberg, JM; Shalek, AK; Sykes, DB | 1 |
| Arbushites, MC; Barkey, N; Howell, MD; Liu, H; Owens, S; Paczesny, S; Pratta, M; Schroeder, MA; Socie, G | 1 |
| Ayers, GD; Cirici, BX; Cross, NCP; Dezern, AE; Elena, C; Fenaux, P; Geissler, K; Gerds, AT; Germing, U; Itzykson, R; Kiladjian, JJ; Kishtagari, A; Komrokji, RS; Luebbert, M; Mendler, JH; Mesa, RA; Montalban-Bravo, G; Moyo, TK; Nazha, A; Onida, F; Padron, E; Patnaik, MM; Pfeilstöecker, M; Platzbecker, U; Pleyer, L; Santini, V; Sanz, GF; Savona, MR; Seegmiller, AC; Solary, E; Steensma, DP; Tibes, R; Valent, P; van de Loosdrecht, AA; Wiseman, DH; Zhang, J | 1 |
2 review(s) available for pyrroles and incb039110
| Article | Year |
|---|---|
Novel Oral Therapies for Psoriasis and Psoriatic Arthritis.
Topics: Adamantane; Adenosine; Adenosine A3 Receptor Antagonists; Administration, Oral; Arthritis, Psoriatic; Azetidines; Biological Factors; Biological Therapy; Clinical Trials as Topic; Humans; Isonicotinic Acids; Janus Kinases; Niacinamide; Phosphodiesterase 4 Inhibitors; Piperidines; Protein Kinase Inhibitors; Psoriasis; Purines; Pyrazoles; Pyrimidines; Pyrroles; Receptors, Lysosphingolipid; rho-Associated Kinases; Sulfonamides; Thalidomide; Thiazoles | 2016 |
Early phase studies of JAK1 selective inhibitors in rheumatoid arthritis.
Topics: Acetonitriles; Arthritis, Rheumatoid; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Heterocyclic Compounds, 3-Ring; Humans; Janus Kinase 1; Janus Kinase Inhibitors; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Triazoles | 2021 |
6 trial(s) available for pyrroles and incb039110
| Article | Year |
|---|---|
Evaluation of Clinical Cardiac Safety of Itacitinib, a JAK1 Inhibitor, in Healthy Participants.
Topics: Acetonitriles; Adolescent; Adult; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart Rate; Humans; Janus Kinase 1; Janus Kinase Inhibitors; Male; Middle Aged; Pyrazoles; Pyrimidines; Pyrroles; Young Adult | 2020 |
Efficacy and safety of itacitinib versus placebo in combination with corticosteroids for initial treatment of acute graft-versus-host disease (GRAVITAS-301): a randomised, multicentre, double-blind, phase 3 trial.
Topics: Acetonitriles; Adrenal Cortex Hormones; Double-Blind Method; Female; Graft vs Host Disease; Humans; Pyrazoles; Pyrimidines; Pyrroles; Treatment Outcome | 2022 |
A Phase 1/2 Study of the Oral Janus Kinase 1 Inhibitors INCB052793 and Itacitinib Alone or in Combination With Standard Therapies for Advanced Hematologic Malignancies.
Topics: Acetonitriles; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Hematologic Neoplasms; Humans; Janus Kinase 1; Janus Kinase Inhibitors; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Pyrazoles; Pyrimidines; Pyrroles | 2022 |
Exploring the safety, effect on the tumor microenvironment, and efficacy of itacitinib in combination with epacadostat or parsaclisib in advanced solid tumors: a phase I study.
Topics: Acetonitriles; Humans; Neoplasms; Oximes; Pyrazoles; Pyrimidines; Pyrroles; Pyrrolidines; Sulfonamides; Tumor Microenvironment | 2022 |
A biomarker signature to predict complete response to itacitinib and corticosteroids in acute graft-versus-host disease.
Topics: Acetonitriles; Acute Disease; Adrenal Cortex Hormones; Biomarkers; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Proteomics; Pyrazoles; Pyrimidines; Pyrroles | 2022 |
The ABNL-MARRO 001 study: a phase 1-2 study of randomly allocated active myeloid target compound combinations in MDS/MPN overlap syndromes.
Topics: Acetonitriles; Cytidine Deaminase; Decitabine; DNA; Humans; Methyltransferases; Myelodysplastic-Myeloproliferative Diseases; Prospective Studies; Pyrazoles; Pyrimidines; Pyrroles; Quality of Life; Syndrome | 2022 |
4 other study(ies) available for pyrroles and incb039110
| Article | Year |
|---|---|
The Effect of Renal Impairment on the Pharmacokinetics and Safety of Itacitinib.
Topics: Acetonitriles; Adult; Aged; Area Under Curve; Blood Proteins; Dialysis Solutions; Female; Humans; Janus Kinase 1; Kidney; Male; Middle Aged; Protein Binding; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Pyrroles; Renal Dialysis; Renal Elimination; Renal Insufficiency | 2020 |
Effect of Hepatic Impairment on the Pharmacokinetics of Itacitinib.
Topics: Acetonitriles; Adult; Aged; Area Under Curve; Body Mass Index; Female; Humans; Janus Kinase Inhibitors; Liver Diseases; Liver Function Tests; Male; Metabolic Clearance Rate; Middle Aged; Patient Acuity; Protein Binding; Pyrazoles; Pyrimidines; Pyrroles | 2021 |
Selective inhibition of JAK3 signaling is sufficient to reverse alopecia areata.
Topics: Administration, Topical; Alopecia Areata; Animals; Azetidines; CD8-Positive T-Lymphocytes; Cytokines; Isonicotinic Acids; Janus Kinase 1; Janus Kinase 2; Janus Kinase 3; Macrophages; Mice, Inbred C3H; Nitriles; NK Cell Lectin-Like Receptor Subfamily K; Piperidines; Protein Kinase Inhibitors; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Triazoles | 2021 |
JAK inhibition in a patient with a STAT1 gain-of-function variant reveals STAT1 dysregulation as a common feature of aplastic anemia.
Topics: Acetonitriles; Adolescent; Anemia, Aplastic; CD8-Positive T-Lymphocytes; Gain of Function Mutation; Humans; Janus Kinase Inhibitors; Male; Pyrazoles; Pyrimidines; Pyrroles; STAT1 Transcription Factor | 2022 |