pyrroles has been researched along with hts 466284 in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (12.00) | 29.6817 |
| 2010's | 21 (84.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bae, Y; Fujii, T; Hirakawa, K; Iwata, C; Kaminishi, M; Kano, MR; Kataoka, K; Kiyono, K; Komuro, A; Miyazono, K; Morishita, Y; Nishiyama, N; Oka, M; Ouchi, Y; Yashiro, M | 1 |
| Dolman, ME; Fretz, MM; Goldschmeding, R; Hennink, WE; Kok, RJ; Lacombe, M; Nguyen, TQ; Pato, J; Prakash, J; Storm, G | 1 |
| Iwata, C; Kano, MR; Kataoka, K; Komuta, Y; Miyazono, K; Morishita, Y; Oka, M; Ouchi, Y; Shirai, YT | 1 |
| Kawamura, K; Kawano, H; Kimura-Kuroda, J; Komuta, Y; Raisman, G; Sango, K; Teng, X; Yoshioka, N | 1 |
| Hisanaga, S; Kawamura, K; Kawano, H; Kimura-Kuroda, J; Saito, T; Yoshioka, N | 1 |
| Chenausky, KL; Gauger, KJ; Murray, ME; Schneider, SS | 1 |
| Cabral, H; Chen, Q; Kano, MR; Kataoka, K; Kimura, M; Matsumoto, Y; Miyazono, K; Mizuno, K; Murakami, M; Nishiyama, N; Terada, Y; Uesaka, M | 1 |
| Dhasarathy, A; Mav, D; Phadke, D; Shah, RR; Wade, PA | 1 |
| Fujita, Y; Imai, E; Ito, Y; Kinashi, H; Maruyama, S; Matsui, K; Matsuo, S; Mizuno, M; Mizuno, T; Noda, Y; Sawai, A; Shimizu, H; Suzuki, Y; Takei, Y | 1 |
| Agrawal, V; Santhiago, MR; Singh, V; Wilson, SE | 1 |
| Barcellos-Hoff, MH; Hardee, ME; Lonning, SM; Marciscano, AE; Medina-Ramirez, CM; Narayana, A; Zagzag, D | 1 |
| Brann, D; Cheng, H; Cheng, T; Li, S; Sun, Y; Wang, R; Wei, Z; Xu, H; Yang, F; Yuan, Y | 1 |
| Ishii, K; Mori, A; Nakahara, T; Sakamoto, K; Ueda, K | 1 |
| Beljaars, L; Lacombe, M; Poelstra, K; Post, E; Prakash, J; Reker-Smit, C; van Beuge, MM | 1 |
| Bansal, SS; Celia, C; Ferrari, M; Ferrati, S; Grattoni, A; Palapattu, G; Zabre, E | 1 |
| Cagalinec, M; Jaskova, K; Jurkovicova, D; Lacinova, L; Pavlovicova, M | 1 |
| Grisanti, S; Lüke, J; Lüke, M; Nassar, K; Soliman, M; Tura, A | 1 |
| Dooley, S; Goumans, MJ; Karkampouna, S; Kruithof-de Julio, M; Ten Dijke, P | 1 |
| Chen, LF; Chen, YC; Chiang, CF; Hsieh, WY; Lin, WL; Wu, SK | 1 |
| Cao, ZT; Chen, KG; Luo, YL; Shen, S; Wang, J; Wang, YC; Yu, XY; Zhao, G; Zuo, ZQ | 1 |
| Fang, L; Jiang, K; Wang, D; Wang, J; Zhao, J; Zhu, L | 1 |
| Bermudez, JY; Cheng, YQ; Clark, AF; Liu, X; Mao, W; Patel, GC; Webber, HC | 1 |
| Cotrina, ML; Gu, S; He, X; Huang, JH; Liu, W; Nedergaard, M; Shapiro, LA; Wang, EW; Wang, F; Wang, W; Wang, X | 1 |
| Akimoto, Y; Ikehara, S; Ikehara, Y; Kume, M; Nakanishi, H; Ohara, O; Yamaguchi, T; Yamamoto, K | 1 |
| Basta, MD; Paulson, H; Walker, JL | 1 |
25 other study(ies) available for pyrroles and hts 466284
| Article | Year |
|---|---|
Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling.
Topics: Animals; Cell Line, Tumor; Drug Delivery Systems; Endothelium, Vascular; Humans; Immunohistochemistry; Mice; Mice, Inbred BALB C; Nanoparticles; Neoplasms; Protein Serine-Threonine Kinases; Pyrazoles; Pyrroles; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Signal Transduction; Transforming Growth Factor beta | 2007 |
Intervention in growth factor activated signaling pathways by renally targeted kinase inhibitors.
Topics: Cells, Cultured; Chemistry, Pharmaceutical; Drug Carriers; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Erlotinib Hydrochloride; Fibrosis; Gene Expression Regulation; Humans; Intercellular Signaling Peptides and Proteins; Kidney Tubules, Proximal; Kinetics; Muramidase; Phosphorylation; Protein Kinase Inhibitors; Pyrazoles; Pyrroles; Quinazolines; Receptors, Transforming Growth Factor beta; Signal Transduction; Transforming Growth Factor beta | 2008 |
Comparison of the effects of the kinase inhibitors imatinib, sorafenib, and transforming growth factor-beta receptor inhibitor on extravasation of nanoparticles from neovasculature.
Topics: Animals; Benzamides; Benzenesulfonates; Cell Line, Tumor; Extravasation of Diagnostic and Therapeutic Materials; Humans; Imatinib Mesylate; Mice; Mice, Inbred BALB C; Nanoparticles; Neoplasms; Niacinamide; Phenylurea Compounds; Piperazines; Protein Kinase Inhibitors; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Receptors, Transforming Growth Factor beta; Signal Transduction; Sorafenib; Vascular Endothelial Growth Factor A | 2009 |
An in vitro model of the inhibition of axon growth in the lesion scar formed after central nervous system injury.
Topics: Analysis of Variance; Animals; Animals, Newborn; Antigens; Astrocytes; Axons; Bromodeoxyuridine; Cell Count; Cell Proliferation; Cells, Cultured; Cerebellum; Cerebral Cortex; Chondroitin Sulfates; Coculture Techniques; Fibroblasts; Fibronectins; Gene Expression Regulation; Meninges; Nerve Tissue Proteins; Neural Inhibition; Neurites; Neurons; Platelet Endothelial Cell Adhesion Molecule-1; Proteoglycans; Pyrazoles; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, EphB2; Semaphorin-3A; Tenascin; Transforming Growth Factor beta1 | 2010 |
Small molecule inhibitor of type I transforming growth factor-β receptor kinase ameliorates the inhibitory milieu in injured brain and promotes regeneration of nigrostriatal dopaminergic axons.
Topics: Animals; Antigens; Axons; Brain Injuries; Cicatrix; Corpus Striatum; Disease Models, Animal; Enzyme Inhibitors; Glial Fibrillary Acidic Protein; Leukocyte Common Antigens; Male; Mice; Mice, Inbred ICR; Nerve Regeneration; Protein Serine-Threonine Kinases; Proteoglycans; Pyrazoles; Pyrroles; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Signal Transduction; Smad2 Protein; Substantia Nigra; Tyrosine 3-Monooxygenase | 2011 |
SFRP1 reduction results in an increased sensitivity to TGF-β signaling.
Topics: Animals; Down-Regulation; Epithelial-Mesenchymal Transition; Gene Knockdown Techniques; Homeodomain Proteins; Humans; Intercellular Signaling Peptides and Proteins; Membrane Proteins; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Pyrazoles; Pyrroles; Repressor Proteins; Signal Transduction; Telomerase; Transforming Growth Factor beta; Zinc Finger E-box Binding Homeobox 2 | 2011 |
Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size.
Topics: Animals; Antineoplastic Agents; Drug Carriers; Humans; Liposomes; Mice; Mice, Inbred BALB C; Micelles; Organoplatinum Compounds; Pancreatic Neoplasms; Particle Size; Permeability; Polyethylene Glycols; Pyrazoles; Pyrroles; Transforming Growth Factor beta | 2011 |
The transcription factors Snail and Slug activate the transforming growth factor-beta signaling pathway in breast cancer.
Topics: Acetylation; Benzamides; Breast Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Movement; Dioxoles; Down-Regulation; Epithelial-Mesenchymal Transition; Female; Genetic Loci; Histones; Humans; Intercellular Junctions; Mammary Glands, Human; Phenotype; Protein Serine-Threonine Kinases; Pyrazoles; Pyrroles; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; RNA, Messenger; Signal Transduction; Snail Family Transcription Factors; Substrate Specificity; Transcription Factors; Transcription, Genetic; Transforming Growth Factor beta | 2011 |
Transforming growth factor-β induces vascular endothelial growth factor-C expression leading to lymphangiogenesis in rat unilateral ureteral obstruction.
Topics: Animals; Cell Line; Disease Models, Animal; Fibroblasts; Fibrosis; Humans; Kidney Tubules; Lymphangiogenesis; Macrophages; Male; Membrane Glycoproteins; Mice; Protein Serine-Threonine Kinases; Pyrazoles; Pyrroles; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptor, Transforming Growth Factor-beta Type I; Receptors, Cell Surface; Receptors, Transforming Growth Factor beta; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Time Factors; Transforming Growth Factor beta1; Up-Regulation; Ureteral Obstruction; Vascular Endothelial Growth Factor C | 2012 |
Stromal fibroblast-bone marrow-derived cell interactions: implications for myofibroblast development in the cornea.
Topics: Actins; Animals; Bone Marrow Cells; Cell Communication; Cell Separation; Cell Transdifferentiation; Coculture Techniques; Corneal Keratocytes; Corneal Stroma; Enzyme Inhibitors; Female; Fluorescent Antibody Technique, Indirect; Gene Expression; Green Fluorescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myofibroblasts; Pyrazoles; Pyrroles; Signal Transduction; Transfection; Transforming Growth Factor beta1 | 2012 |
Resistance of glioblastoma-initiating cells to radiation mediated by the tumor microenvironment can be abolished by inhibiting transforming growth factor-β.
Topics: Animals; Antibodies, Neutralizing; Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy; DNA Damage; DNA, Neoplasm; Female; Glioblastoma; Humans; Mice; Mice, Inbred C57BL; Mink; Neoplastic Stem Cells; Neural Stem Cells; Pyrazoles; Pyrroles; Radiation Tolerance; Radiation-Sensitizing Agents; Signal Transduction; Transforming Growth Factor beta; Tumor Microenvironment | 2012 |
A new antifibrotic target of Ac-SDKP: inhibition of myofibroblast differentiation in rat lung with silicosis.
Topics: Actins; Angiotensin II; Animals; Cell Differentiation; Collagen Type I; Collagen Type III; Lung; Male; Myofibroblasts; Oligopeptides; Pyrazoles; Pyrroles; Rats; Rats, Wistar; Receptors, Transforming Growth Factor beta; RNA, Messenger; Silicosis; Transforming Growth Factor beta1 | 2012 |
Protective effects of TGF-β inhibitors in a rat model of NMDA-induced retinal degeneration.
Topics: Animals; Benzamides; Capillaries; Dioxoles; Disease Models, Animal; Intravitreal Injections; Male; N-Methylaspartate; Pyrazoles; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Transforming Growth Factor beta; Retinal Diseases; Retinal Ganglion Cells; Retinal Vessels; Transforming Growth Factor beta | 2013 |
Enhanced effectivity of an ALK5-inhibitor after cell-specific delivery to hepatic stellate cells in mice with liver injury.
Topics: Animals; Collagen; Disease Models, Animal; Hepatic Stellate Cells; Hepatocytes; Humans; Liver Cirrhosis; Male; Mice; Protein Serine-Threonine Kinases; Pyrazoles; Pyrroles; Rats; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Transforming Growth Factor beta | 2013 |
Validated RP-HPLC method for the simultaneous analysis of gemcitabine and LY-364947 in liposomal formulations.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cattle; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Deoxycytidine; Drug Stability; Gemcitabine; Liposomes; Pancreatic Neoplasms; Pyrazoles; Pyrroles | 2013 |
TGFβ1 downregulates neurite outgrowth, expression of Ca2+ transporters, and mitochondrial dynamics of in vitro cerebellar granule cells.
Topics: Action Potentials; Animals; Boron Compounds; Calcium; Cell Enlargement; Cells, Cultured; Central Nervous System Agents; Cerebellum; Inositol 1,4,5-Trisphosphate Receptors; Membrane Potentials; Mitochondria; Mitochondrial Dynamics; Neurites; Neurons; Pyrazoles; Pyrroles; Rats; Rats, Wistar; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Transforming Growth Factor beta1 | 2014 |
A TGF-β receptor 1 inhibitor for prevention of proliferative vitreoretinopathy.
Topics: Animals; Cell Proliferation; Cell Transdifferentiation; Disease Models, Animal; Fibroblasts; Humans; Intravitreal Injections; Protein Serine-Threonine Kinases; Pyrazoles; Pyrroles; Rabbits; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Retinal Pigment Epithelium; Tenon Capsule; Tetrazolium Salts; Thiazoles; Vitreoretinopathy, Proliferative | 2014 |
Inhibition of TGFβ type I receptor activity facilitates liver regeneration upon acute CCl4 intoxication in mice.
Topics: Animals; Biomarkers; Carbon Tetrachloride Poisoning; Hepatic Stellate Cells; Hepatocytes; Liver; Liver Regeneration; Male; Mice, Inbred C57BL; Protein Serine-Threonine Kinases; Pyrazoles; Pyrroles; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Signal Transduction; Transforming Growth Factor beta | 2016 |
Targeting microbubbles-carrying TGFβ1 inhibitor combined with ultrasound sonication induce BBB/BTB disruption to enhance nanomedicine treatment for brain tumors.
Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Capillary Permeability; Drug Delivery Systems; Male; Mice; Mice, Inbred ICR; Mice, SCID; Microbubbles; Nanomedicine; Pyrazoles; Pyrroles; Rats; Rats, Sprague-Dawley; Sonication; Transforming Growth Factor beta1 | 2015 |
Promoting tumor penetration of nanoparticles for cancer stem cell therapy by TGF-β signaling pathway inhibition.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Humans; Nanocapsules; Neoplastic Stem Cells; Protein Serine-Threonine Kinases; Pyrazoles; Pyrroles; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; RNA, Small Interfering; Signal Transduction; Transforming Growth Factor beta; Treatment Outcome | 2016 |
Jumonji AT-rich interactive domain 1B overexpression is associated with the development and progression of glioma.
Topics: Animals; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Glioma; Humans; Immunohistochemistry; Jumonji Domain-Containing Histone Demethylases; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Nuclear Proteins; Phosphorylation; Pyrazoles; Pyrroles; Repressor Proteins; RNA, Messenger; Smad2 Protein; Spheroids, Cellular | 2016 |
HDAC Inhibitor-Mediated Epigenetic Regulation of Glaucoma-Associated TGFβ2 in the Trabecular Meshwork.
Topics: Acetylation; Animals; Cattle; Cells, Cultured; Epigenesis, Genetic; Glaucoma, Open-Angle; Histone Deacetylase Inhibitors; Pyrazoles; Pyrroles; RNA, Messenger; Trabecular Meshwork; Transforming Growth Factor beta2 | 2016 |
NKCC1 up-regulation contributes to early post-traumatic seizures and increased post-traumatic seizure susceptibility.
Topics: Ammonia; Animals; Animals, Newborn; Bumetanide; Cell Count; Cerebral Cortex; Disease Models, Animal; Epilepsy, Post-Traumatic; Evoked Potentials; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Phosphopyruvate Hydratase; Pyrazoles; Pyrroles; Seizures; Sodium Potassium Chloride Symporter Inhibitors; Solute Carrier Family 12, Member 2; Up-Regulation; Wakefulness | 2017 |
TGF-β signaling promotes tube-structure-forming growth in pancreatic duct adenocarcinoma.
Topics: Animals; Benzamides; Carcinogenesis; Carcinoma, Pancreatic Ductal; Cell Culture Techniques; Cell Line, Tumor; Dioxoles; Disease Models, Animal; Humans; Mice; Mice, Transgenic; Pancreatic Neoplasms; Pyrazoles; Pyrroles; Recombinant Proteins; RNA-Seq; Signal Transduction; Spheroids, Cellular; Transforming Growth Factor beta1 | 2019 |
The local wound environment is a key determinant of the outcome of TGFβ signaling on the fibrotic response of CD44
Topics: Actins; Animals; Blotting, Western; Capsule Opacification; Cataract Extraction; Cell Proliferation; Chick Embryo; Collagen Type I; Disease Models, Animal; Fibronectins; Fibrosis; Hyaluronan Receptors; Imidazoles; Integrin alphaVbeta3; Microscopy, Fluorescence; Myofibroblasts; Posterior Capsule of the Lens; Postoperative Complications; Pyrazoles; Pyrroles; Quinoxalines; Receptor, Transforming Growth Factor-beta Type I; Signal Transduction; Transforming Growth Factor beta; Wound Healing | 2021 |