Page last updated: 2024-08-18

pyrroles and hc-067047

pyrroles has been researched along with hc-067047 in 51 studies

Research

Studies (51)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	39 (76.47)	24.3611
2020's	12 (23.53)	2.80

Authors

Authors	Studies
De Ridder, D; Everaerts, W; Fanger, CM; Gevaert, T; Ghosh, D; Gilbert, JP; Hayward, NJ; McNamara, CR; Moran, MM; Nilius, B; Owsianik, G; Strassmaier, T; Uykal, E; Vennekens, R; Voets, T; Vriens, J; Xue, F; Zhen, X	1
Benemei, S; Creminon, C; Fusi, C; Geppetti, P; Materazzi, S; Nassini, R; Nilius, B; Patacchini, R; Pedretti, P; Prenen, J	1
Delamere, NA; Mandal, A; Shahidullah, M	2
Cardouat, G; Dahan, D; Ducret, T; Gillibert-Duplantier, J; Marthan, R; Martin, E; Savineau, JP	1
Dahan, D; Ducret, T; Estève, E; Marthan, R; Quignard, JF; Savineau, JP	1
Berrout, J; Boukelmoune, N; Mamenko, M; O'Neil, RG; Pochynyuk, O; Zaika, OL	1
Cai, S; Fu, Z; Hu, J; Huang, C; Liedtke, W; Paudel, O; Sham, JS; Xia, Y	1
Chen, L; Jie, PH; Li, L; Lu, ZH; Yin, J; Zhou, LB	1
Abogadie, FC; Bunnett, NW; Darby, B; Grace, MS; Lieu, T; McIntyre, P; Veldhuis, N	1
Merrill, L; Vizzard, MA	1
Bachelor, M; Carreno, FR; Cunningham, JT; Nedungadi, TP; Park, YH; Saxena, A	1
Brenner, D; Chen, Y; Fang, Q; Gereau, RW; Kanju, P; Lee, SH; Lee, W; Liedtke, W; Moore, C; Parekh, PK; Wang, F	1
Koide, M; Wellman, GC	1
Chen, L; Du, Y; Hong, Z; Jie, P; Li, L; Li, Y; Lu, Z; Zhou, L; Zhou, R; Zhou, Y	1
López-Zapata, DF; Sánchez, JC; Wilkins, RJ	1
Chang, I; Park, WS; Shin, DM; Son, GY; Yang, YM	1
Chen, L; Du, Y; Hong, Z; Jie, P; Li, Y; Lin, L; Tian, Y; Zhou, L	1
Awwad, K; Dan, Q; Erfinanda, L; Fleming, I; Goldenberg, N; Kapus, A; Kuebler, WM; Kuppe, H; Lee, WL; Liedtke, WB; Lv, L; Michalick, L; Nouailles, G; Rotstein, O; Szaszi, K; Tabuchi, A; Tang, C; Vogelzang, A; Wang, L; Witzenrath, M; Yin, J; Zhang, H	1
Jo, AO; Križaj, D; MacAulay, N; Phuong, TT; Ryskamp, DA; Verkman, AS; Yarishkin, O	1
Deevska, G; Kline, RH; Ma, F; Nikolova-Karakashian, M; Westlund, KN; Zhang, LP	1
Huang, QY; Wang, D; Yang, F; Yang, LL; Yuan, GR; Zhou, L	1
Hashitani, H; Isogai, A; Lee, K; Mitsui, R	1
Ambati, B; Frye, AM; Hageman, G; Iuso, A; Jo, AO; Križaj, D; Lakk, M; Phuong, TT; Prestwich, GD; Redmon, SN; Ryskamp, DA; Torrejon, KY; Xu, Y; Yarishkin, O	1
Ahmed, S; Aziz, Q; Blackshaw, LA; Boundouki, G; Broad, J; Bulmer, DC; Chan, C; Cibert-Goton, V; Hockley, JRF; Knowles, CH; Kung, V; McGuire, C; Peiris, M; Reed, D; Sanger, GJ; Thaha, MA	1
Chen, L; Ding, D; Dong, Q; Du, YM; Fu, D; Guo, KF; Han, B; Li, J; Liao, YH; Qian, C; Wang, BB; Wu, QF; Zhao, N	1
Fukuda, I; Hasegawa, M; Higashino, K; Hinata, M; Horita, N; Ikeda, M; Imai, M; Imai, S; Kanemasa, T; Minami, M; Morioka, Y; Morita, A; Sakaguchi, G; Sanaki, T; Soga, M; Tsuchida, J; Yamamoto, M; Yamane, S; Yoshioka, T	1
Chen, L; Du, Y; Huang, S; Men, C; Qi, M; Wang, Z; Wu, C; Zhou, L	1
Li, B; Liang, H; Ou-Yang, Q; Xu, M	1
Baines, CP; Domeier, TL; Hill, MA; Jones, JL; Karasseva, NG; Krenz, M; Lambert, MD; Lindman, BR; Nourian, Z; Peana, D; Veteto, AB	1
Pei, ZM; Zhu, YH	1
Chandrasekaran, G; Kumar, D; Kumar, T; Mahobiya, A; Parida, S; Rungsung, S; Singh, TU	1
Chen, D; Shen, J; Tan, T; Tu, L; Wang, S; Wang, Y	1
An, D; Chen, A; Chen, L; Du, Y; Li, Y; Sha, S; Wang, Z; Wu, C; Xu, W; Zhou, L; Zhu, Y	1
Alves, VS; Costa, R; Dias, FC; Figueiredo, CP; Matias, DO; Miranda, ALP; Passos, GF	1
Jensen-Jarolim, E; Pfanzagl, B; Pfragner, R	1
An, D; Chen, L; Men, C; Qi, M; Wang, Z; Xu, W; Zhan, Y; Zhou, L	1
Campbell, SE; Drescher, C; Girard, BM; Hennig, GW; Heppner, TJ; Hsiang, H; Nelson, MT; Perkins, M; Tooke, K; Vizzard, MA	1
Mori-Kawabe, M; Tsushima, H	1
Cheng, Q; Jia, X; Sheng, D; Wu, J; Xiao, C; Yang, M; Zhang, S	1
Jin, R; Jin, Z; Paudel, O; Sham, JSK; Xia, L; Xia, Y	1
A Voss, A; Bogdanik, L; Brown, NL; Denman, K; Dupont, C; Ladle, DR; Lutz, CM; Myers, JH; Novak, K; Rich, MM; Sullivan, JM; Sumner, CJ; Walker, PV	1
Baj, A; Bistoletti, M; Giaroni, C; Marcozzi, C; Moriondo, A; Negrini, D; Solari, E	1
Blazer-Yost, BL; Fulkerson, D; Hochstetler, AE; Preston, DC; Reed, MM; Shim, JW; Smith, HM; Territo, PR	1
Amano, T; Fujii, N; Honda, Y; Kenny, GP; Kondo, N; McGarr, GW; Nishiyasu, T	1
Ding, X; Fan, X; Han, J; Ning, L; Tang, S; Wang, C	1
Hishinuma, S; Michinaga, S; Mizuguchi, H; Onishi, K; Shimizu, K	1
Liu, XY; Xu, J; Zhang, H; Zhang, P	1
Lee, WJ; Shim, WS	1
He, KM; Pu, JT; Teng, ZY; Wu, YF; Zhang, DG; Zhang, T	1
Cai, N; Chen, KM; Cui, BB; Gao, YH; Jing, LL; Liu, TZ; Ma, HP; Miao, LW; Sun, YH; Wang, JF; Wei, Z; Xian, CJ; Xuan, YY	1

Other Studies

51 other study(ies) available for pyrroles and hc-067047

Article	Year
Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis. Proceedings of the National Academy of Sciences of the United States of America, 2010, Nov-02, Volume: 107, Issue:44 Topics: Animals; Antineoplastic Agents, Alkylating; Cyclophosphamide; Cystitis; Humans; Membrane Transport Modulators; Mice; Mice, Knockout; Morpholines; Pyrroles; Rats; Rats, Wistar; TRPV Cation Channels; Urinary Bladder; Urination; Urothelium	2010
TRPA1 and TRPV4 mediate paclitaxel-induced peripheral neuropathy in mice via a glutathione-sensitive mechanism. Pflugers Archiv : European journal of physiology, 2012, Volume: 463, Issue:4 Topics: Acetanilides; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cold Temperature; Drug Hypersensitivity; Glutathione; Hyperalgesia; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Paclitaxel; Peripheral Nervous System Diseases; Purines; Pyrroles; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels	2012
TRPV4 in porcine lens epithelium regulates hemichannel-mediated ATP release and Na-K-ATPase activity. American journal of physiology. Cell physiology, 2012, Jun-15, Volume: 302, Issue:12 Topics: Adenosine Triphosphate; Animals; Calcium; Connexin 43; Connexins; Dose-Response Relationship, Drug; Enzyme Activation; Epithelium; Eye Proteins; Glycyrrhetinic Acid; Lens, Crystalline; Leucine; Morpholines; Osmotic Pressure; Probenecid; Propidium; Pyrroles; Sodium-Potassium-Exchanging ATPase; src-Family Kinases; Sulfonamides; Swine; Time Factors; Tissue Culture Techniques; TRPV Cation Channels	2012
Involvement of TRPV1 and TRPV4 channels in migration of rat pulmonary arterial smooth muscle cells. Pflugers Archiv : European journal of physiology, 2012, Volume: 464, Issue:3 Topics: Animals; Calcium; Capsaicin; Cell Movement; Cytoskeleton; Morpholines; Myocytes, Smooth Muscle; Phorbol Esters; Pulmonary Artery; Pyrroles; Rats; RNA, Messenger; TRPV Cation Channels	2012
Implication of the ryanodine receptor in TRPV4-induced calcium response in pulmonary arterial smooth muscle cells from normoxic and chronically hypoxic rats. American journal of physiology. Lung cellular and molecular physiology, 2012, Nov-01, Volume: 303, Issue:9 Topics: Animals; Caffeine; Calcium Channel Agonists; Calcium Signaling; Cell Hypoxia; Cells, Cultured; Dantrolene; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Macrocyclic Compounds; Male; Morpholines; Muscle Contraction; Muscle Relaxants, Central; Myocytes, Smooth Muscle; Oxazoles; Patch-Clamp Techniques; Phorbols; Pulmonary Artery; Pyrroles; Rats; Rats, Wistar; Ryanodine; Ryanodine Receptor Calcium Release Channel; TRPV Cation Channels	2012
Discrete control of TRPV4 channel function in the distal nephron by protein kinases A and C. The Journal of biological chemistry, 2013, Jul-12, Volume: 288, Issue:28 Topics: Animals; Calcium; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Fura-2; In Vitro Techniques; Indoles; Isoquinolines; Kidney Tubules, Collecting; Maleimides; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Morpholines; Nephrons; Perfusion; Phorbol Esters; Protein Kinase C; Protein Kinase Inhibitors; Protein Transport; Pyrroles; Signal Transduction; Sulfonamides; TRPV Cation Channels	2013
TRPV4 channel contributes to serotonin-induced pulmonary vasoconstriction and the enhanced vascular reactivity in chronic hypoxic pulmonary hypertension. American journal of physiology. Cell physiology, 2013, Oct-01, Volume: 305, Issue:7 Topics: Animals; Calcium Signaling; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Familial Primary Pulmonary Hypertension; Hypertension, Pulmonary; Hypoxia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Pulmonary Artery; Pyrroles; Serotonin; Sulfonamides; Time Factors; TRPV Cation Channels; Vasoconstriction; Vasoconstrictor Agents	2013
Transient receptor potential vanilloid 4 mediates hypotonicity-induced enhancement of synaptic transmission in hippocampal slices. CNS neuroscience & therapeutics, 2013, Volume: 19, Issue:11 Topics: Animals; Excitatory Postsynaptic Potentials; Hippocampus; Male; Mice; Mice, Inbred ICR; Morpholines; Organ Culture Techniques; Osmotic Pressure; Pyrroles; Synaptic Transmission; TRPV Cation Channels	2013
The tyrosine kinase inhibitor bafetinib inhibits PAR2-induced activation of TRPV4 channels in vitro and pain in vivo. British journal of pharmacology, 2014, Volume: 171, Issue:16 Topics: Animals; HEK293 Cells; Humans; Hyperalgesia; Leucine; Male; Mice, Inbred C57BL; Morpholines; Oligopeptides; Pain; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Receptor, PAR-2; Sulfonamides; TRPV Cation Channels; Trypsin	2014
Intravesical TRPV4 blockade reduces repeated variate stress-induced bladder dysfunction by increasing bladder capacity and decreasing voiding frequency in male rats. American journal of physiology. Regulatory, integrative and comparative physiology, 2014, Aug-15, Volume: 307, Issue:4 Topics: Administration, Intravesical; Animals; Disease Models, Animal; Gene Expression Regulation; Leucine; Male; Morpholines; Pyrroles; Rats; Rats, Wistar; RNA, Messenger; Sulfonamides; Time Factors; TRPV Cation Channels; Urinary Bladder; Urinary Bladder, Neurogenic; Urinary Incontinence, Stress; Urodynamics; Urological Agents	2014
Angiotensin II induces membrane trafficking of natively expressed transient receptor potential vanilloid type 4 channels in hypothalamic 4B cells. American journal of physiology. Regulatory, integrative and comparative physiology, 2014, Oct-15, Volume: 307, Issue:8 Topics: Angiotensin II; Animals; Calcium; Cell Line; Cells, Cultured; Hypothalamus; Leucine; Membrane Microdomains; Morpholines; Protein Transport; Pyrroles; Rats; Receptor, Angiotensin, Type 1; Signal Transduction; src-Family Kinases; Sulfonamides; TRPV Cation Channels	2014
TRPV4 is necessary for trigeminal irritant pain and functions as a cellular formalin receptor. Pain, 2014, Volume: 155, Issue:12 Topics: Animals; Butadienes; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Fixatives; Formaldehyde; Keratinocytes; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Morpholines; Neurons; Nitriles; Pain; Pyrroles; Trigeminal Ganglion; TRPV Cation Channels; Ubiquitin Thiolesterase; Vibrissae	2014
Activation of TRPV4 channels does not mediate inversion of neurovascular coupling after SAH. Acta neurochirurgica. Supplement, 2015, Volume: 120 Topics: Animals; Astrocytes; Calcium Signaling; Disease Models, Animal; Hyperemia; Male; Morpholines; Organ Culture Techniques; Pyrroles; Rats, Sprague-Dawley; Subarachnoid Hemorrhage; TRPV Cation Channels	2015
Activation of Transient Receptor Potential Vanilloid 4 is Involved in Neuronal Injury in Middle Cerebral Artery Occlusion in Mice. Molecular neurobiology, 2016, Volume: 53, Issue:1 Topics: Animals; Disease Models, Animal; Hippocampus; Infarction, Middle Cerebral Artery; Male; Mice; Morpholines; Phosphatidylinositol 3-Kinases; Pyrroles; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury; TRPV Cation Channels	2016
TRPV4 channels activity in bovine articular chondrocytes: regulation by obesity-associated mediators. Cell calcium, 2014, Volume: 56, Issue:6 Topics: Animals; Calcium; Cartilage, Articular; Cattle; Cells, Cultured; Chondrocytes; Gadolinium; Insulin; Interleukin-1beta; Leptin; Morpholines; Obesity; Osmotic Pressure; Patch-Clamp Techniques; Pyrroles; Resistin; Ruthenium Red; TRPV Cation Channels; Tumor Necrosis Factor-alpha	2014
Hypotonic stress induces RANKL via transient receptor potential melastatin 3 (TRPM3) and vaniloid 4 (TRPV4) in human PDL cells. Journal of dental research, 2015, Volume: 94, Issue:3 Topics: Biomechanical Phenomena; Bone Remodeling; Boron Compounds; Calcium Channel Blockers; Calcium Signaling; Cell Culture Techniques; Cells, Cultured; Gene Silencing; Humans; Hypotonic Solutions; Morpholines; Osteoprotegerin; Periodontal Ligament; Phorbols; Pregnenolone; Pyrroles; RANK Ligand; RNA, Messenger; RNA, Small Interfering; Ruthenium Red; Signal Transduction; Stress, Mechanical; TRPM Cation Channels; TRPV Cation Channels	2015
Activation of transient receptor potential vanilloid 4 induces apoptosis in hippocampus through downregulating PI3K/Akt and upregulating p38 MAPK signaling pathways. Cell death & disease, 2015, Jun-04, Volume: 6 Topics: Animals; Anthracenes; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Down-Regulation; Enzyme Activation; Hippocampus; Imidazoles; Infarction, Middle Cerebral Artery; JNK Mitogen-Activated Protein Kinases; Leucine; Male; MAP Kinase Signaling System; Mice; Mice, Inbred ICR; Morpholines; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Pyridines; Pyrroles; Sulfonamides; TRPV Cation Channels	2015
Role of Transient Receptor Potential Vanilloid 4 in Neutrophil Activation and Acute Lung Injury. American journal of respiratory cell and molecular biology, 2016, Volume: 54, Issue:3 Topics: Acute Lung Injury; Animals; Bone Marrow Transplantation; Calcium Signaling; Capillary Permeability; Disease Models, Animal; Humans; Hydrochloric Acid; Lung; Male; Mice, Knockout; Morpholines; Neutrophil Activation; Neutrophils; Pneumonia; Pulmonary Edema; Pyrroles; TRPV Cation Channels	2016
Damage to lens fiber cells causes TRPV4-dependent Src family kinase activation in the epithelium. Experimental eye research, 2015, Volume: 140 Topics: Adenosine Triphosphate; Animals; Blotting, Western; Epithelium; Lens, Crystalline; Mannitol; Morpholines; Osmotic Pressure; Phosphorylation; Pyrroles; Signal Transduction; Sodium Chloride; Sodium-Potassium-Exchanging ATPase; src-Family Kinases; Sus scrofa; TRPV Cation Channels	2015
TRPV4 and AQP4 Channels Synergistically Regulate Cell Volume and Calcium Homeostasis in Retinal Müller Glia. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Sep-30, Volume: 35, Issue:39 Topics: Animals; Aquaporin 4; Calcium; Calcium Signaling; Cell Size; Gene Expression; Homeostasis; Leucine; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Neuroglia; Oocytes; Potassium Channels, Inwardly Rectifying; Pyrroles; Retina; Sulfonamides; TRPV Cation Channels; Water; Xenopus	2015
Alcohol and high fat induced chronic pancreatitis: TRPV4 antagonist reduces hypersensitivity. Neuroscience, 2015, Dec-17, Volume: 311 Topics: Analgesics; Animals; Diet, High-Fat; Disease Models, Animal; Drug Evaluation, Preclinical; Ethanol; Hot Temperature; Loperamide; Male; Morpholines; Oxidative Stress; Pain; Pain Threshold; Pancreatitis, Chronic; Pyrroles; Random Allocation; Rats, Inbred F344; Receptors, Opioid, mu; Touch; TRPV Cation Channels	2015
Suppression of TRPV4 channels ameliorates anti-dipsogenic effects under hypoxia in the subfornical organ of rats. Scientific reports, 2016, 07-20, Volume: 6 Topics: Animals; Calcium; Cell Line; Drinking; Gadolinium; HEK293 Cells; Heme Oxygenase (Decyclizing); Humans; Hydrogen-Ion Concentration; Hypoxia; Male; Morpholines; Neurons; Pyrroles; Pyrrolidines; Rats; Rats, Sprague-Dawley; Sodium; Subfornical Organ; Temperature; TRPV Cation Channels; Urea	2016
Functional coupling of TRPV4 channels and BK channels in regulating spontaneous contractions of the guinea pig urinary bladder. Pflugers Archiv : European journal of physiology, 2016, Volume: 468, Issue:9 Topics: Animals; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Guinea Pigs; Indoles; Large-Conductance Calcium-Activated Potassium Channels; Male; Morpholines; Muscle Contraction; Nifedipine; Peptides; Potassium Channel Blockers; Pyrroles; TRPV Cation Channels; Urinary Bladder	2016
TRPV4 regulates calcium homeostasis, cytoskeletal remodeling, conventional outflow and intraocular pressure in the mammalian eye. Scientific reports, 2016, 08-11, Volume: 6 Topics: Animals; Calcium; Cell Membrane; Cytoskeleton; Homeostasis; Humans; Intraocular Pressure; Mice; Morpholines; Ocular Hypertension; Pyrroles; Trabecular Meshwork; TRPV Cation Channels	2016
Ex vivo study of human visceral nociceptors. Gut, 2018, Volume: 67, Issue:1 Topics: Adenosine Triphosphate; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bradykinin Receptor Antagonists; Drug Evaluation, Preclinical; Gastrointestinal Agents; Humans; Indoles; Intestines; Morpholines; Nociceptors; Physical Stimulation; Pyrroles; Serotonin Receptor Agonists; Tissue Culture Techniques; TRPV Cation Channels	2018
Blockage of transient receptor potential vanilloid 4 alleviates myocardial ischemia/reperfusion injury in mice. Scientific reports, 2017, 02-16, Volume: 7 Topics: Animals; Apoptosis; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression; Gene Knockout Techniques; Glycogen Synthase Kinase 3 beta; Heart Function Tests; Mice; Molecular Targeted Therapy; Morpholines; Myocardial Reperfusion Injury; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrroles; Signal Transduction; TRPV Cation Channels	2017
Sensitization of transient receptor potential vanilloid 4 and increasing its endogenous ligand 5,6-epoxyeicosatrienoic acid in rats with monoiodoacetate-induced osteoarthritis. Pain, 2018, Volume: 159, Issue:5 Topics: Animals; Arthritis, Experimental; Disease Models, Animal; Ganglia, Spinal; Hand Strength; Iodoacetic Acid; Leucine; Male; Morpholines; Neurons; Osteoarthritis; Pain; Pain Measurement; Phosphorylation; Pyrroles; Rats; Rats, Sprague-Dawley; Sulfonamides; TRPV Cation Channels	2018
Transient Receptor Potential Vanilloid 4 Activation-Induced Increase in Glycine-Activated Current in Mouse Hippocampal Pyramidal Neurons. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 45, Issue:3 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Evoked Potentials; Glycine; Hippocampus; Leucine; Mice; Mice, Inbred ICR; Morpholines; Patch-Clamp Techniques; Protein Kinase C; Pyramidal Cells; Pyrroles; Receptors, Glycine; Signal Transduction; Strychnine; Sulfonamides; TRPV Cation Channels	2018
TRPV4 promotes the migration and invasion of glioma cells via AKT/Rac1 signaling. Biochemical and biophysical research communications, 2018, 09-05, Volume: 503, Issue:2 Topics: Blotting, Western; Cell Line, Tumor; Cell Movement; Glioma; Humans; Leucine; Morpholines; Neoplasm Invasiveness; Proto-Oncogene Proteins c-akt; Pyrroles; rac1 GTP-Binding Protein; Signal Transduction; Sulfonamides; TRPV Cation Channels	2018
TRPV4 increases cardiomyocyte calcium cycling and contractility yet contributes to damage in the aged heart following hypoosmotic stress. Cardiovascular research, 2019, 01-01, Volume: 115, Issue:1 Topics: Age Factors; Animals; Calcium; Calcium Signaling; Disease Models, Animal; Humans; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Osmotic Pressure; Pyrroles; Sarcoplasmic Reticulum; TRPV Cation Channels	2019
Sustenance of endothelial cell stability in septic mice through appropriate activation of transient receptor potential vanilloid-4. Cellular and molecular biology (Noisy-le-Grand, France), 2018, May-30, Volume: 64, Issue:7 Topics: Animals; Apoptosis; Biomarkers; Blood Coagulation; Caspase 3; Cytoprotection; Disease Models, Animal; Endothelial Cells; Interleukin-6; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Morpholines; Pyrroles; Sepsis; TRPV Cation Channels; Tumor Necrosis Factor-alpha	2018
Kaempferol-induces vasorelaxation via endothelium-independent pathways in rat isolated pulmonary artery. Pharmacological reports : PR, 2018, Volume: 70, Issue:5 Topics: Animals; Apamin; Barium Compounds; Calcium Chloride; Chlorides; Dose-Response Relationship, Drug; Endothelium, Vascular; Estradiol; Fulvestrant; Glyburide; In Vitro Techniques; Indomethacin; Isoquinolines; Kaempferols; Male; Morpholines; NG-Nitroarginine Methyl Ester; Oxadiazoles; Peptides; Potassium; Pulmonary Artery; Pyrroles; Quinoxalines; Rats; Sulfonamides; Tetraethylammonium; Vasodilation; Vasodilator Agents	2018
TRPV4 channels stimulate Ca Brain research bulletin, 2019, Volume: 146 Topics: Animals; Apoptosis; Brain Injuries; Calcium; Cell Death; Cell Survival; Cerebral Hemorrhage; Endoplasmic Reticulum Stress; Inositol 1,4,5-Trisphosphate Receptors; Leucine; Male; Mice; Mice, Inbred C57BL; Morpholines; Neurons; Pyrroles; Sulfonamides; TRPV Cation Channels; Unfolded Protein Response	2019
TRPV4-induced inflammatory response is involved in neuronal death in pilocarpine model of temporal lobe epilepsy in mice. Cell death & disease, 2019, 05-16, Volume: 10, Issue:6 Topics: Animals; Astrocytes; Epilepsy, Temporal Lobe; Inflammasomes; Inflammation; Leucine; Male; Mice; Mice, Inbred ICR; Microglia; Morpholines; Neurons; Pilocarpine; Pyrroles; Status Epilepticus; Sulfonamides; TRPV Cation Channels	2019
The selective TRPV4 channel antagonist HC-067047 attenuates mechanical allodynia in diabetic mice. European journal of pharmacology, 2019, Aug-05, Volume: 856 Topics: Animals; Body Temperature; Body Weight; Diabetic Neuropathies; Ganglia, Spinal; Gene Expression Regulation; Hyperalgesia; Locomotion; Male; Mice; Morpholines; Psychomotor Performance; Pyrroles; Sciatic Nerve; TRPV Cation Channels	2019
The Transient Receptor Potential Vanilloid 4 Agonist RN-1747 Inhibits the Calcium Response to Histamine. Pharmacology, 2019, Volume: 104, Issue:3-4 Topics: Calcium; Cell Line, Tumor; HeLa Cells; Histamine; Humans; Morpholines; Pyrroles; Sulfonamides; TRPV Cation Channels	2019
Transient receptor potential vanilloid 4 is involved in the upregulation of connexin expression following pilocarpine-induced status epilepticus in mice. Brain research bulletin, 2019, Volume: 152 Topics: Animals; Connexin 43; Connexins; Epilepsy; Gap Junction beta-1 Protein; Hippocampus; Leucine; Male; Mice; Mice, Inbred ICR; Morpholines; Pilocarpine; Pyrroles; Status Epilepticus; Sulfonamides; TRPV Cation Channels	2019
TRPV4 blockade reduces voiding frequency, ATP release, and pelvic sensitivity in mice with chronic urothelial overexpression of NGF. American journal of physiology. Renal physiology, 2019, 12-01, Volume: 317, Issue:6 Topics: Adenosine Triphosphate; Animals; Brefeldin A; Female; Mice; Mice, Inbred C57BL; Mice, Transgenic; Morpholines; Nerve Growth Factor; Pelvis; Physical Stimulation; Protein Synthesis Inhibitors; Pyrroles; TRPV Cation Channels; Urinary Bladder; Urinary Bladder, Overactive; Urination; Urothelium	2019
Central Transient Receptor Potential Vanilloid 4 Contributes to Systemic Water Homeostasis through Urinary Excretion. Biological & pharmaceutical bulletin, 2019, Volume: 42, Issue:11 Topics: Animals; Atrial Natriuretic Factor; Dinoprost; Diuresis; Drinking; Homeostasis; Indomethacin; Male; Morpholines; Phorbol Esters; Pyrroles; Rats; Rats, Wistar; Ruthenium Red; TRPV Cation Channels; Urination; Vasopressins	2019
TRPV4 Mediates Cardiac Fibrosis via the TGF-β1/Smad3 Signaling Pathway in Diabetic Rats. Cardiovascular toxicology, 2020, Volume: 20, Issue:5 Topics: Animals; Cell Proliferation; Cells, Cultured; Collagen Type I; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Fibroblasts; Fibrosis; Male; Morpholines; Myocardium; Phosphorylation; Pyrroles; Rats, Sprague-Dawley; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta1; TRPV Cation Channels	2020
Cytochrome P450 Epoxygenase-Dependent Activation of TRPV4 Channel Participates in Enhanced Serotonin-Induced Pulmonary Vasoconstriction in Chronic Hypoxic Pulmonary Hypertension. Analytical cellular pathology (Amsterdam), 2020, Volume: 2020 Topics: Amides; Animals; Chronic Disease; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Eicosanoids; Hypertension, Pulmonary; Hypoxia; Ion Channel Gating; Male; Mice, Inbred C57BL; Morpholines; Pulmonary Artery; Pyrroles; Serotonin; TRPV Cation Channels; Vasoconstriction	2020
TRPV4 Antagonism Prevents Mechanically Induced Myotonia. Annals of neurology, 2020, Volume: 88, Issue:2 Topics: Animals; Anthracenes; Isometric Contraction; Mice; Mice, Knockout; Morpholines; Muscle, Skeletal; Myotonia Congenita; Pyrroles; TRPV Cation Channels	2020
TRPV4 channels' dominant role in the temperature modulation of intrinsic contractility and lymph flow of rat diaphragmatic lymphatics. American journal of physiology. Heart and circulatory physiology, 2020, 08-01, Volume: 319, Issue:2 Topics: Animals; Diaphragm; Female; In Vitro Techniques; Lymph; Lymphatic Vessels; Male; Morpholines; Muscle Contraction; Muscle, Smooth; Periodicity; Pyrroles; Rats; Rats, Wistar; Ruthenium Red; Signal Transduction; Temperature; Time Factors; TRPV Cation Channels	2020
TRPV4 antagonists ameliorate ventriculomegaly in a rat model of hydrocephalus. JCI insight, 2020, 09-17, Volume: 5, Issue:18 Topics: Animals; Cerebral Cortex; Disease Models, Animal; Hydrocephalus; Morpholines; Nervous System Malformations; Pyrroles; Rats; TRPV Cation Channels	2020
TRPV4 channel blockade does not modulate skin vasodilation and sweating during hyperthermia or cutaneous postocclusive reactive and thermal hyperemia. American journal of physiology. Regulatory, integrative and comparative physiology, 2021, 04-01, Volume: 320, Issue:4 Topics: Adult; Female; Humans; Hyperemia; Hyperthermia; Leucine; Male; Membrane Transport Modulators; Microdialysis; Morpholines; Piperidines; Pyrroles; Quinolines; Regional Blood Flow; Skin; Sulfonamides; Sweating; Time Factors; TRPV Cation Channels; Vasodilation; Young Adult	2021
Role of TRPV4-P2X7 Pathway in Neuropathic Pain in Rats with Chronic Compression of the Dorsal Root Ganglion. Neurochemical research, 2021, Volume: 46, Issue:8 Topics: Animals; Ganglia, Spinal; Hyperalgesia; Leucine; Male; Morpholines; Nerve Compression Syndromes; Neuralgia; Purinergic P2X Receptor Antagonists; Pyrroles; Rats, Wistar; Receptors, Purinergic P2X7; Rosaniline Dyes; Signal Transduction; Sulfonamides; TRPV Cation Channels	2021
Pharmacological Inhibition of Transient Receptor Potential Vanilloid 4 Reduces Vasogenic Edema after Traumatic Brain Injury in Mice. Biological & pharmaceutical bulletin, 2021, Volume: 44, Issue:11 Topics: Animals; Astrocytes; Blood-Brain Barrier; Brain Edema; Brain Injuries, Traumatic; Disease Models, Animal; Male; Matrix Metalloproteinase 9; Mice; Morpholines; Pyrroles; Real-Time Polymerase Chain Reaction; Sulfonamides; TRPV Cation Channels; Vascular Endothelial Growth Factor A	2021
Identification of TRPV4 as a novel target in invasiveness of colorectal cancer. BMC cancer, 2021, Nov-23, Volume: 21, Issue:1 Topics: Cell Line, Tumor; Cell Movement; Colonic Neoplasms; Epithelial-Mesenchymal Transition; Female; HCT116 Cells; Humans; Immunohistochemistry; Male; Middle Aged; Morpholines; Neoplasm Invasiveness; Neoplasm Metastasis; Proto-Oncogene Proteins c-akt; Pyrroles; Rectal Neoplasms; RNA, Small Interfering; Transfection; TRPV Cation Channels; Zinc Finger E-box-Binding Homeobox 1	2021
Cutaneous Neuroimmune Interactions of TSLP and TRPV4 Play Pivotal Roles in Dry Skin-Induced Pruritus. Frontiers in immunology, 2021, Volume: 12 Topics: Animals; Cells, Cultured; Cytokines; Ganglia, Spinal; Humans; Keratinocytes; Male; Mast Cells; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Morpholines; Neuroimmunomodulation; Neurons; Pruritus; Pyrroles; Skin; Thymic Stromal Lymphopoietin; TRPV Cation Channels	2021
Transient receptor potential vanilloid 4 promotes the growth of non-small cell lung cancer by regulating Foxp3. Acta biochimica Polonica, 2022, Jan-07, Volume: 69, Issue:1 Topics: A549 Cells; Aged; Apoptosis; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Female; Forkhead Transcription Factors; Humans; Leucine; Lung Neoplasms; Male; Middle Aged; Morpholines; Pyrroles; Sulfonamides; TRPV Cation Channels	2022
Simulated microgravity-induced oxidative stress and loss of osteogenic potential of osteoblasts can be prevented by protection of primary cilia. Journal of cellular physiology, 2023, Volume: 238, Issue:11 Topics: Animals; Cells, Cultured; Cilia; Gravitation; Morpholines; Osteoblasts; Osteogenesis; Oxidative Stress; Pyrroles; Rats; Reactive Oxygen Species; TRPV Cation Channels; Weightlessness	2023