pyrroles has been researched along with gv 196771a in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 6 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnaby, R; Bottacini, M; Hoke, JF; Iavarone, L; Preston, GC | 1 |
| Arban, R; Belardetti, F; Bettelini, L; Carignani, C; Corsi, M; Dal Forno, G; Di Fabio, R; Maraia, G; Mugnaini, M; Quartaroli, M; Ratti, E; Reggiani, A; Trist, DG; Ugolini, A | 1 |
| Bordi, F; Quartaroli, M | 1 |
| Chazot, PL; Chopra, B; Stephenson, FA | 1 |
| Bettelini, L; Corsi, M; Fasdelli, N; Maraia, G; Quartaroli, M | 1 |
| Alvaro, G; Bertani, B; Donati, D; Fabio, RD; Giacobbe, S; Lynn, SM; Marchioro, C; Palma, C | 1 |
| Backonja, MM; Dotson, RM; Dworkin, RH; Galer, BS; Katz, NP; Meisner, PD; Quessy, SN; Rauck, RL; Rowbotham, MC; Wallace, MS | 1 |
| Barnaby, RJ; Baughman, TM; Bertolotti, L; Humphreys, JE; Jordan, KH; Mote, AL; Polli, JW; Read, KD; Serabjit-Singh, CJ; Vitulli, G; Webster, LO | 1 |
2 trial(s) available for pyrroles and gv 196771a
| Article | Year |
|---|---|
First time in human for GV196771: interspecies scaling applied on dose selection.
Topics: Administration, Oral; Animals; Area Under Curve; Body Weight; Brain; Dogs; Excitatory Amino Acid Antagonists; Glycine Agents; Humans; Indoles; Injections, Intravenous; Macaca fascicularis; Male; Metabolic Clearance Rate; Organ Size; Pyrroles; Rats; Species Specificity | 1999 |
A randomized, double-blind, placebo-controlled trial of a glycine antagonist in neuropathic pain.
Topics: Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Glycine; Glycine Agents; Hot Temperature; Humans; Indoles; Male; Middle Aged; Pain; Pain Measurement; Patient Satisfaction; Peripheral Nervous System Diseases; Pyrroles; Sensory Thresholds; Treatment Outcome | 2002 |
6 other study(ies) available for pyrroles and gv 196771a
| Article | Year |
|---|---|
Potent antihyperalgesic activity without tolerance produced by glycine site antagonist of N-methyl-D-aspartate receptor GV196771A.
Topics: Analgesics, Non-Narcotic; Animals; Behavior, Animal; Binding, Competitive; Cerebral Cortex; Drug Tolerance; Electrophysiology; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Hyperalgesia; In Vitro Techniques; Indoles; Male; Mice; Pain Measurement; Patch-Clamp Techniques; Pyrroles; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1999 |
Modulation of nociceptive transmission by NMDA/glycine site receptor in the ventroposterolateral nucleus of the thalamus.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Excitatory Amino Acid Antagonists; Hot Temperature; Indoles; Male; Morphine; Nerve Compression Syndromes; Neurons; Nociceptors; Pain Measurement; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Reference Values; Sciatic Nerve; Synaptic Transmission; Touch; Ventral Thalamic Nuclei | 2000 |
Characterization of the binding of two novel glycine site antagonists to cloned NMDA receptors: evidence for two pharmacological classes of antagonists.
Topics: Animals; Cells, Cultured; Excitatory Amino Acid Antagonists; Glycine Agents; Indoles; Prosencephalon; Pyrroles; Rats; Receptors, N-Methyl-D-Aspartate | 2000 |
GV196771A, an NMDA receptor/glycine site antagonist, attenuates mechanical allodynia in neuropathic rats and reduces tolerance induced by morphine in mice.
Topics: Animals; Behavior, Animal; Binding Sites; Constriction, Pathologic; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Excitatory Amino Acid Antagonists; Glycine; Indoles; Ligation; Male; Mice; Morphine; Narcotics; Neuralgia; Pain; Pain Measurement; Pain Threshold; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sciatic Nerve; Stress, Mechanical | 2001 |
Novel stereocontrolled addition of allylmetal reagents to alpha-imino esters: efficient synthesis of chiral tetrahydroquinoline derivatives.
Topics: Allyl Compounds; Catalysis; Imines; Indicators and Reagents; Indoles; Metals; Molecular Structure; Oxidation-Reduction; Pyrroles; Quinolones; Stereoisomerism; Structure-Activity Relationship | 2002 |
The systemic exposure of an N-methyl-D-aspartate receptor antagonist is limited in mice by the P-glycoprotein and breast cancer resistance protein efflux transporters.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Carbamates; Cell Line; Chromatography, Liquid; Furans; Indoles; Male; Mass Spectrometry; Mice; Mice, Knockout; Pyrroles; Receptors, N-Methyl-D-Aspartate; Sulfonamides; Tetrahydroisoquinolines; Time Factors | 2004 |