pyrroles has been researched along with gsk 1838705a in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Anderson, K; Atkins, C; Chamberlain, SD; Dumble, M; Gontarek, RR; Groy, A; Korenchuk, S; Kruger, RG; Kumar, R; Lapierre, RR; Leperi, D; Liu, Q; Maksimchuk, KR; Rabindran, SK; Rowand, JL; Sabbatini, P; Shotwell, JB; Suravajjala, S; Wilson, JW; Yang, J | 1 |
| Kelleher, FC; McDermott, R | 1 |
| Ardini, E; Galvani, A; Magnaghi, P; Menichincheri, M; Orsini, P | 1 |
| Chen, M; Hui, H; Jin, B; Ma, P; Pei, S; Shen, F; Wang, Z; Zhou, W; Zhou, X | 1 |
| Bovée, JV; Briaire-de Bruijn, I; Cleton-Jansen, AM; Cleven, AH; Danen, EH; De Jong, Y; Fletcher, JA; Peterse, EF | 1 |
| Carella, N; Carr, BI; Cavallini, A; D'Alessandro, R; Lippolis, C; Messa, C; Refolo, MG | 1 |
| Chen, L; Chen, S; Wang, Q; Yang, HS; Zhang, Y; Zheng, H; Zhu, J | 1 |
2 review(s) available for pyrroles and gsk 1838705a
| Article | Year |
|---|---|
The emerging pathogenic and therapeutic importance of the anaplastic lymphoma kinase gene.
Topics: Anaplastic Lymphoma Kinase; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Chromosome Aberrations; Chromosomes, Human, Pair 2; Drug Synergism; Gene Amplification; Humans; Lung Neoplasms; Lymphoma, Large-Cell, Anaplastic; Mutation; Neoplasms; Neuroblastoma; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptor, IGF Type 1 | 2010 |
Anaplastic Lymphoma Kinase: role in specific tumours, and development of small molecule inhibitors for cancer therapy.
Topics: Anaplastic Lymphoma Kinase; Animals; Crizotinib; Genetic Predisposition to Disease; Humans; Molecular Structure; Mutation; Neoplasms; Piperidines; Protein-Tyrosine Kinases; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Receptor Protein-Tyrosine Kinases | 2010 |
5 other study(ies) available for pyrroles and gsk 1838705a
| Article | Year |
|---|---|
GSK1838705A inhibits the insulin-like growth factor-1 receptor and anaplastic lymphoma kinase and shows antitumor activity in experimental models of human cancers.
Topics: Anaplastic Lymphoma Kinase; Animals; Antineoplastic Agents; Blood Glucose; Cell Proliferation; Enzyme Activation; Humans; Mice; Phosphorylation; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptor, IGF Type 1; Receptor, Insulin; Signal Transduction; Xenograft Model Antitumor Assays | 2009 |
GSK1838705A, an IGF-1R inhibitor, inhibits glioma cell proliferation and suppresses tumor growth in vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Glioma; Humans; Mice; Mice, Nude; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Receptor, IGF Type 1; Signal Transduction; Xenograft Model Antitumor Assays | 2015 |
No preclinical rationale for IGF1R directed therapy in chondrosarcoma of bone.
Topics: Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell Survival; Chondrosarcoma; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Molecular Targeted Therapy; Pyrimidines; Pyrroles; Receptor, IGF Type 1; Receptors, Somatomedin; Signal Transduction | 2016 |
Strong enhancement by IGF1-R antagonists of hepatocellular carcinoma cell migration inhibition by Sorafenib and/or vitamin K1.
Topics: Actin Cytoskeleton; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Humans; Imidazoles; Insulin-Like Growth Factor I; Liver Neoplasms; Niacinamide; Phenylurea Compounds; Phosphorylation; Protein Kinase Inhibitors; Pyrazines; Pyrimidines; Pyrroles; Sorafenib; Vitamin K 1 | 2018 |
IGF-1R inhibition induces MEK phosphorylation to promote survival in colon carcinomas.
Topics: Animals; Apoptosis; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cell Survival; Class I Phosphatidylinositol 3-Kinases; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Kinase 1; Mice; Mitogen-Activated Protein Kinase Kinases; Phosphorylation; Proto-Oncogene Proteins p21(ras); Pyrazoles; Pyrimidines; Pyrroles; Receptor, IGF Type 1; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Triazines; Xenograft Model Antitumor Assays | 2020 |