pyrroles has been researched along with glutamic acid in 74 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (16.22) | 18.7374 |
| 1990's | 9 (12.16) | 18.2507 |
| 2000's | 23 (31.08) | 29.6817 |
| 2010's | 26 (35.14) | 24.3611 |
| 2020's | 4 (5.41) | 2.80 |
| Authors | Studies |
|---|---|
| Phang, JM | 1 |
| Meister, A; Seddon, AP; Zhao, KY | 1 |
| Jones, ME | 1 |
| Leong, SF; McGeer, EG; Thompson, SG; Wong, PT | 1 |
| Jones, ME; Small, C | 1 |
| Beale, SI; Weinstein, JD | 1 |
| Henslee, JG; Jones, ME; Small, C; Wakabayashi, Y | 1 |
| Smith, RJ | 1 |
| Bergamaschi, A; Malgaroli, A; Scheller, RH; Ting, AE; Tsien, RW; Villa, A; Wendland, B | 1 |
| Dailey, HA; Woodard, SI | 1 |
| Beale, SI; Mayer, SM; Rieble, S | 1 |
| Castillo, PE; Nicoll, RA; Weisskopf, MG; Zalutsky, RA | 1 |
| Jayaswal, RK; Kaenjak, A; Townsend, DE; Wilkinson, BJ | 1 |
| Battle, A; Fukuda, H; Riley, P; Washbrook, R | 1 |
| Hall, ED; Smith, SL | 1 |
| Barczak, A; Konradi, C; Leveque, JC; Lewis, SE; Macías, W; Rajadhyaksha, A | 1 |
| Ahn, S; Ginty, DD; Linden, DJ | 1 |
| Chen, Z; Deore, B; Nagaoka, T | 1 |
| Bunch, L; Frydenvang, K; Krogsgaard-Larsen, P; Madsen, U; Norrby, PO | 1 |
| Pittman, QJ; Price, CJ | 1 |
| Huong, NT; Inatomi, H; Yoshihashi, T | 1 |
| Almo, SC; Cahill, SM; Evans, GB; Fedorov, A; Furneaux, RH; Kicska, GA; Lewandowicz, A; Schramm, VL; Shi, W; Tyler, PC | 1 |
| STRECKER, HJ | 2 |
| PEISACH, J; STRECKER, HJ | 1 |
| Bae, AH; Fujita, N; Hatano, T; Ihara, H; Kaneko, K; Shinkai, S; Takafuji, M; Takeuchi, M | 1 |
| Holladay, JE; Muzatko, DS; Werpy, TA | 1 |
| Anisman, H; Khan, S; Merali, Z; Michaud, DS; Shippy, SA | 1 |
| Brosnan, ME; Haslett, MR; Pink, D; Walters, B | 1 |
| Tan, F; Wang, XR; Yang, HH; Zhang, SQ; Zhuang, ZX | 1 |
| Barnes, NY; Parent, AT; Sisodia, SS; Taniguchi, Y; Thinakaran, G | 1 |
| Bösel, J; Dirnagl, U; Djoufack, PC; Endres, M; Fink, KB; Gandor, F; Harms, C; Harms, U; Hörtnagl, H; Megow, D; Synowitz, M | 1 |
| Gangjee, A; Kisliuk, RL; McGuire, JJ; Zeng, Y | 1 |
| Aiello, A; D'Esposito, M; Fattorusso, E; Menna, M; Müller, WE; Perović-Ottstadt, S; Schröder, HC | 1 |
| Gajhede, M; Greenwood, JR; Kasper, C; Kastrup, JS; Kristensen, AS; Liljefors, T; Mirza, O; Olsen, L; Pickering, DS; Schousboe, A; Sigurskjold, BW; Wätjen, F | 1 |
| Hurley, LM | 1 |
| Castaño, A; Dominguez, E; Escribano, A; Fernandez, C; Ho, KH; Hornback, WJ; Jimenez, A; Nisenbaum, ES; Rankl, N; Tromiczak, E; Zarrinmayeh, H; Zimmerman, DM | 1 |
| Aiello, A; Fattorusso, E; Giordano, A; Menna, M; Müller, WE; Perović-Ottstadt, S; Schröder, HC | 1 |
| Li, C; Tang, L; Yang, X; Zhu, Y | 1 |
| Chapman, J; Maggio, N; Segal, M; Shavit, E | 1 |
| Adermark, L; Lovinger, DM; Talani, G | 1 |
| Banik, NL; Del Re, AM; Ray, SK; Sribnick, EA; Woodward, JJ | 1 |
| Honig, A; Miller, G; Mittler, R; Stein, H; Suzuki, N; Zilberstein, A | 1 |
| Ammam, M; Fransaer, J | 1 |
| Boyko, M; Dubilet, M; Klin, Y; Kotz, R; Ohayon, S; Shapira, Y; Teichberg, VI; Zlotnik, A | 1 |
| Burkhardt, C; Fuchs, K; Guenther, E; Hellmann, DCh; Kraushaar, U; Parisi, J; von Hauff, E; Weiler, R | 1 |
| Bazer, FW; Burghardt, RC; Johnson, GA; Kim, SW; Knabe, DA; Li, P; Li, X; McKnight, JR; Satterfield, MC; Spencer, TE; Wu, G | 1 |
| Bezerra, SC; de Bem, AF; Duarte, FS; Figueiredo, CP; Mancini, G; Piermartiri, TC; Prediger, RD; Rial, D; Tasca, CI | 1 |
| Baimoukhametova, DV; Bains, JS; Kuzmiski, JB; Marty, V | 1 |
| Gorbacheva, LR; Makarova, AM; Mikhailova, AG; Pinelis, VG; Rumsh, LD; Savinkova, IV; Strukova, SM | 1 |
| Chang, Y; Lin, YW; Wang, SJ | 1 |
| Kang, Y; Lee, M; McGeer, E; McGeer, PL; Suk, K | 1 |
| An, CH; Cho, JH; Choi, IS; Choi, JK; Hur, YK; Jang, IS; Jung, JK | 1 |
| Batalha, VL; Coelho, JE; Diógenes, MJ; Ferreira, DG; Gomes, R; Lopes, LV; Sebastião, AM; Valadas, JS | 1 |
| Ahmed, AH; Garner, PP; Hamada, M; Ohfune, Y; Oswald, RE; Shinada, T; Weerasinghe, L | 1 |
| Bertoldo, DB; de Bem, AF; Herculano, BA; Mancini, G; Martins, WC; Tasca, CI; Vandresen-Filho, S | 1 |
| Cao, Z; Ding, F; Ding, M; Ke, K; Zhang, J; Zhang, Q | 1 |
| Chen, B; Li, Y; Lu, L; Wang, J; Yao, Z; Zhou, H; Zou, C | 1 |
| Batra, B; Kumari, S; Pundir, CS | 1 |
| Cruz-Martínez, AM; Escartín-Pérez, RE; Florán-Garduño, B; García-Iglesias, B; López-Alonso, VE; Mancilla-Díaz, JM; Tejas-Juárez, JG | 1 |
| Acher, F; Bollinger, SR; Conn, PJ; Days, EL; Engers, DW; Field, JR; Gregory, KJ; Hopkins, CR; Hurtado, M; Jalan-Sakrikar, N; Klar, R; Lewis, LM; Lindsley, CW; Mattmann, ME; Melancon, BJ; Niswender, CM; Rigault, D; Utley, TJ; Walker, AG; Weaver, CD; Wood, MR; Xiang, Z; Zamorano, R | 1 |
| Agarwal, NB; Raisuddin, S; Sehar, N; Vohora, D | 1 |
| Arslan, F; Aynacı, E; Şimşek, Ş | 1 |
| AbdElgawad, H; Asard, H; Beemster, GT; De Vos, D; Domagalska, MA; Zinta, G | 1 |
| He, D; Huang, Z; Pu, X; Qin, J; Yin, G; Zou, Y | 1 |
| Bonnemain, JL; Chollet, JF; Lei, ZW; Marhadour, S; Marivingt-Mounir, C; Wu, H; Yang, W | 1 |
| Buonvicino, D; Cavone, L; Chiarugi, A; Felici, R; Gerace, E; Lapucci, A; Mai, A; Valente, S; Zwergel, C | 1 |
| Chen, Y; Gao, XB; Yang, W; Zhang, Y; Zhou, YF | 1 |
| Kumar, RTR; Maity, D | 1 |
| Avila, CC; Damasceno, FS; Elias, MC; Mantilla, BS; Marchese, L; Olavarria, K; Silber, AM; Souza, ROO | 1 |
| Rolev, KD; Shu, XS; Ying, Y | 1 |
| Aqrawe, Z; Bansal, M; Raos, B; Svirskis, D; Wu, Z | 1 |
| Guan, X; Jiang, T; Liu, L; Yin, R; Zhang, K; Zhang, X | 1 |
4 review(s) available for pyrroles and glutamic acid
| Article | Year |
|---|---|
The regulatory functions of proline and pyrroline-5-carboxylic acid.
Topics: Amino Acids; Animals; Biological Transport; Cell Communication; Cell Cycle; Charcoal; Glutamates; Glutamic Acid; Humans; Mitosis; NADP; Neoplasms; Ornithine; Oxidation-Reduction; Phosphoribosyl Pyrophosphate; Proline; Protein Biosynthesis; Purine Nucleotides; Pyrroles; Structure-Activity Relationship | 1985 |
Intestinal ornithine synthesis from glutamic acid.
Topics: Alanine Transaminase; Animals; Arginine; Cats; Glutamates; Glutamic Acid; Intestinal Mucosa; Intestine, Small; Ornithine; Ornithine-Oxo-Acid Transaminase; Pyrroles; Rats | 1985 |
Proline and hydroxyproline metabolism: implications for animal and human nutrition.
Topics: Animal Nutritional Physiological Phenomena; Animals; Arginine; Birds; Chickens; Collagen; Diet; Dietary Supplements; Fishes; Glutamic Acid; Glutamine; Humans; Hydroxyproline; Infant; Infant, Newborn; Milk; Nutritional Requirements; Proline; Pyrroles; Swine | 2011 |
Targeted pharmacotherapy against neurodegeneration and neuroinflammation in early diabetic retinopathy.
Topics: Anti-Inflammatory Agents; Antioxidants; Apoptosis; Astrocytes; beta Catenin; Diabetic Retinopathy; Ependymoglial Cells; Glutamic Acid; Glycogen Synthase Kinase 3 beta; Humans; Inflammation; Microglia; Mitochondria; Molecular Targeted Therapy; Neurodegenerative Diseases; Neuroglia; Neuroprotective Agents; Oxidative Stress; Pyrimidines; Pyrroles; Retinal Ganglion Cells; RNAi Therapeutics; tau Proteins | 2021 |
70 other study(ies) available for pyrroles and glutamic acid
| Article | Year |
|---|---|
Activation of glutamate by gamma-glutamate kinase: formation of gamma-cis-cycloglutamyl phosphate, an analog of gamma-glutamyl phosphate.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aldehyde Oxidoreductases; Chromatography, High Pressure Liquid; Drug Stability; Escherichia coli; Glutamate-5-Semialdehyde Dehydrogenase; Glutamates; Glutamic Acid; Hydroxamic Acids; Kinetics; Molecular Conformation; NADP; Organophosphorus Compounds; Phosphates; Phosphotransferases; Phosphotransferases (Carboxyl Group Acceptor); Pyrroles; Pyrrolidonecarboxylic Acid | 1989 |
Conversion of glutamate to ornithine and proline: pyrroline-5-carboxylate, a possible modulator of arginine requirements.
Topics: Amino Acids; Animals; Arginine; Biotransformation; Glutamates; Glutamic Acid; Humans; Intestinal Mucosa; Kidney; Liver; Ornithine; Ornithine-Oxo-Acid Transaminase; Proline; Proline Oxidase; Pyrroles; Retinal Degeneration; Spleen | 1985 |
Regional distribution in rat brain of 1-pyrroline-5-carboxylate dehydrogenase and its localization to specific glial cells.
Topics: Animals; Brain; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Male; Neuroglia; Ornithine; Proline Oxidase; Pyrroles; Rats; Rats, Inbred Strains | 1985 |
A specific radiochemical assay for pyrroline-5-carboxylate dehydrogenase.
Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Carbon Radioisotopes; Glutamates; Glutamic Acid; Kinetics; Oxidoreductases Acting on CH-NH Group Donors; Pyrroles; Spectrophotometry; Tritium | 1987 |
Separate physiological roles and subcellular compartments for two tetrapyrrole biosynthetic pathways in Euglena gracilis.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Carbon Radioisotopes; Darkness; Euglena gracilis; Glutamates; Glutamic Acid; Glycine; Light; Pyrroles; Subcellular Fractions; Tetrapyrroles | 1983 |
Factors influencing pyrroline 5-carboxylate synthesis from glutamate by rat intestinal mucosa mitochondria.
Topics: Animals; Carbon Radioisotopes; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestine, Small; Kinetics; Male; Mitochondria; Ornithine; Pyridoxal Phosphate; Pyrroles; Rats; Rats, Inbred Strains | 1983 |
A radioisotopic assay for delta 1-pyrroline-5-carboxylate synthase activity.
Topics: Animals; Carbon Radioisotopes; Cell Line; Cricetinae; Glutamates; Glutamic Acid; Ornithine-Oxo-Acid Transaminase; Proline; Pyrroles; Transaminases | 1984 |
Presynaptic component of long-term potentiation visualized at individual hippocampal synapses.
Topics: Amino Acid Sequence; Animals; Calcium-Binding Proteins; Cells, Cultured; Glutamic Acid; Hippocampus; Long-Term Potentiation; Membrane Glycoproteins; Molecular Sequence Data; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Potassium; Presynaptic Terminals; Pyrroles; Rats; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Synaptic Vesicles; Synaptotagmins | 1995 |
Regulation of heme biosynthesis in Escherichia coli.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Coproporphyrinogen Oxidase; Escherichia coli; Feedback; Ferrochelatase; Gene Expression Regulation, Enzymologic; Glutamic Acid; Heme; Hydroxymethylbilane Synthase; Mice; Porphyrins; Pyrroles; Rats; Recombinant Proteins; Tetrapyrroles | 1995 |
Metal requirements of the enzymes catalyzing conversion of glutamate to delta-aminolevulinic acid in extracts of Chlorella vulgaris and Synechocystis sp. PCC 6803.
Topics: Aldehyde Oxidoreductases; Aminolevulinic Acid; Cations, Divalent; Cell-Free System; Chlorella; Cyanobacteria; Eukaryota; Glutamate-tRNA Ligase; Glutamates; Glutamic Acid; Intramolecular Transferases; Isomerases; Pyrroles; Tetrapyrroles | 1994 |
Mediation of hippocampal mossy fiber long-term potentiation by cyclic AMP.
Topics: Animals; Calcium; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Indoles; Isoquinolines; Long-Term Potentiation; Models, Biological; Nerve Fibers; Presynaptic Terminals; Pyramidal Cells; Pyrroles; Sulfonamides; Synaptic Transmission | 1994 |
Proline is biosynthesized from arginine in Staphylococcus aureus.
Topics: Arginine; Bacterial Proteins; Carbon; DNA Transposable Elements; Glutamic Acid; Ornithine; Proline; Pyrroles; Staphylococcus aureus | 1996 |
Stimulation of tetrapyrrole synthesis in mammalian epithelial cells in culture by exposure to aminolaevulinic acid.
Topics: Aminolevulinic Acid; Animals; Arginine; Biological Transport; Carbon Radioisotopes; Cattle; Cell Division; Cell Line; Cycloheximide; Dactinomycin; Epithelium; gamma-Aminobutyric Acid; Glutamic Acid; Heme; Kinetics; Leucine; Mammals; Pyrroles; Radioisotope Dilution Technique; Tetrapyrroles | 1997 |
Tirilazad widens the therapeutic window for riluzole-induced attenuation of progressive cortical degeneration in an infant rat model of the shaken baby syndrome.
Topics: Age Factors; Animals; Battered Child Syndrome; Body Temperature; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Free Radical Scavengers; Glutamic Acid; Head Injuries, Closed; Humans; Hypoxia; Infant; Lipid Peroxidation; Male; Nerve Degeneration; Neuroprotective Agents; Pregnatrienes; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Riluzole; Time Factors | 1998 |
L-Type Ca(2+) channels are essential for glutamate-mediated CREB phosphorylation and c-fos gene expression in striatal neurons.
Topics: Animals; Calcium; Calcium Channel Agonists; Calcium Channels; Calcium Channels, L-Type; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Gene Expression Regulation; Glutamic Acid; Magnesium; Neurons; Phosphorylation; Proto-Oncogene Proteins c-fos; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Sodium | 1999 |
A late phase of cerebellar long-term depression requires activation of CaMKIV and CREB.
Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 4; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cells, Cultured; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Glutamic Acid; Indoles; Long-Term Potentiation; Membrane Potentials; Mice; Neural Inhibition; Patch-Clamp Techniques; Purkinje Cells; Pyrroles; Signal Transduction; Thionucleotides; Transfection | 1999 |
Potential-induced enantioselective uptake of amino acid into molecularly imprinted overoxidized polypyrrole.
Topics: Electrochemistry; Glutamic Acid; Hydrogen-Ion Concentration; Oxidation-Reduction; Polymers; Pyrroles; Spectrometry, Fluorescence; Stereoisomerism | 2000 |
Unprecedented migration of N-alkoxycarbonyl groups in protected pyroglutaminol.
Topics: Formic Acid Esters; Glutamic Acid; Magnetic Resonance Spectroscopy; Molecular Structure; Pyrroles; Quantum Theory; X-Ray Diffraction | 2001 |
Dopamine D4 receptor activation inhibits presynaptically glutamatergic neurotransmission in the rat supraoptic nucleus.
Topics: Animals; Benzamides; Benzazepines; Clozapine; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; Male; Patch-Clamp Techniques; Piperazines; Presynaptic Terminals; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D4; Sulpiride; Supraoptic Nucleus; Synaptic Transmission | 2001 |
Precursors of 2-acetyl-1-pyrroline, a potent flavor compound of an aromatic rice variety.
Topics: Carbon Isotopes; Deuterium; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Indicator Dilution Techniques; Nitrogen Isotopes; Ornithine; Oryza; Plant Leaves; Plant Structures; Proline; Pyrroles; Taste | 2002 |
Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase.
Topics: Animals; Asparagine; Binding Sites; Catalysis; Cattle; Crystallography, X-Ray; Enzyme Inhibitors; Glutamic Acid; Hydrogen Bonding; Hydrogen-Ion Concentration; Hypoxanthine; Imines; Nuclear Magnetic Resonance, Biomolecular; Purine Nucleosides; Purine-Nucleoside Phosphorylase; Pyrimidinones; Pyrroles; Ribonucleosides; Static Electricity; Substrate Specificity; Thermodynamics | 2002 |
The interconversion of glutamic acid and proline. I. The formation of delta1-pyrroline-5-carboxylic acid from glutamic acid in Escherichia coli.
Topics: Carboxylic Acids; Escherichia coli; Glutamates; Glutamic Acid; Proline; Pyrroles | 1957 |
The interconversion of glutamic acid and proline. II. The preparation and properties of delta 1-pyrroline-5-carboxylic acid.
Topics: Carboxylic Acids; Glutamates; Glutamic Acid; Proline; Pyrroles | 1960 |
The interconversion of glutamic acid and proline. V. The reduction of delta 1-pyrroline-5-carboxylic acid to proline.
Topics: Carboxylic Acids; Glutamates; Glutamic Acid; Proline; Pyrroles | 1962 |
Helical superstructure of conductive polymers as created by electrochemical polymerization by using synthetic lipid assemblies as a template.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Electric Conductivity; Electrochemistry; Electrodes; Glutamic Acid; Lipids; Macromolecular Substances; Microscopy, Electron; Microscopy, Electron, Scanning; Molecular Conformation; Oxidation-Reduction; Polymers; Pyrroles; Spectrophotometry; Spectrophotometry, Infrared | 2004 |
Catalytic hydrogenation of glutamic acid.
Topics: Biotechnology; Carbon; Catalysis; Chemistry, Organic; Fermentation; Glutamic Acid; Hydrogen; Magnetic Resonance Spectroscopy; Models, Chemical; Phosphoric Acids; Pyrroles; Pyrrolidines; Pyrrolidonecarboxylic Acid; Spectrophotometry; Time Factors | 2004 |
Does amygdaloid corticotropin-releasing hormone (CRH) mediate anxiety-like behaviors? Dissociation of anxiogenic effects and CRH release.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Behavior, Animal; Bombesin; Brain Chemistry; Corticotropin-Releasing Hormone; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Eating; Electroshock; Environment; Glutamic Acid; Hormone Antagonists; Male; Microdialysis; Peptide Fragments; Pyrimidines; Pyrroles; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone | 2004 |
Assay and subcellular localization of pyrroline-5-carboxylate dehydrogenase in rat liver.
Topics: Animals; Glutamic Acid; Liver; Male; Mitochondria; NADP; Ornithine; Ornithine-Oxo-Acid Transaminase; Proline; Proline Oxidase; Pyrroles; Rats; Rats, Sprague-Dawley; Rotenone; Subcellular Fractions; Ultracentrifugation | 2004 |
Surface molecularly imprinted nanowires for biorecognition.
Topics: Aluminum Oxide; Arginine; Glutamic Acid; Nanotechnology; Phenylalanine; Polymers; Pyrroles; Silanes | 2005 |
Presenilin attenuates receptor-mediated signaling and synaptic function.
Topics: Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Carbamates; Carbazoles; Cell Adhesion Molecules; Cell Line, Tumor; Cell Membrane; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DCC Receptor; Dipeptides; Endopeptidases; Excitatory Postsynaptic Potentials; Genes, DCC; Glutamic Acid; Indoles; Lidocaine; Membrane Proteins; Memory; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurites; Neuroblastoma; Neurons; Piperazines; Presenilin-1; Protein Processing, Post-Translational; Pyrroles; Quinoxalines; Rats; Receptors, Cell Surface; Recombinant Fusion Proteins; Second Messenger Systems; Synaptic Transmission; Transfection; Tumor Suppressor Proteins | 2005 |
Neuroprotective effects of atorvastatin against glutamate-induced excitotoxicity in primary cortical neurones.
Topics: Acyl Coenzyme A; Animals; Apoptosis; Atorvastatin; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Glucose; Glutamic Acid; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemia; Hypoxia-Ischemia, Brain; Mitochondria; Neurons; Neuroprotective Agents; Neurotoxins; Pyrroles; Rats; Receptors, Glutamate | 2005 |
Synthesis of classical, four-carbon bridged 5-substituted furo[2,3-d]pyrimidine and 6-substituted pyrrolo[2,3-d]pyrimidine analogues as antifolates.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Furans; Glutamic Acid; Humans; Peptide Synthases; Pyrimidines; Pyrimidinones; Pyrroles; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase | 2005 |
Novel bioactive bromopyrrole alkaloids from the Mediterranean sponge Axinella verrucosa.
Topics: Alkaloids; Animals; Calcium; Cell Line; Chromatography, Thin Layer; Excitatory Amino Acid Antagonists; Glutamic Acid; Magnetic Resonance Spectroscopy; Molecular Structure; Neurons; Porifera; Pyrroles; Quisqualic Acid; Serotonin; Serotonin Antagonists; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Fast Atom Bombardment | 2006 |
The structure of a mixed GluR2 ligand-binding core dimer in complex with (S)-glutamate and the antagonist (S)-NS1209.
Topics: Animals; Binding Sites; Crystallography, X-Ray; Dimerization; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Hydrogen Bonding; Macromolecular Substances; Models, Molecular; Molecular Structure; Protein Structure, Quaternary; Pyrroles; Quinoxalines; Rats; Receptors, AMPA; Recombinant Proteins; Tetrahydroisoquinolines; Thermodynamics | 2006 |
Different serotonin receptor agonists have distinct effects on sound-evoked responses in inferior colliculus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Animals; Chiroptera; Dose-Response Relationship, Drug; Electrodes; Electrophysiology; Evoked Potentials, Auditory; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Inferior Colliculi; Iontophoresis; Male; Pyrazines; Pyridines; Pyrroles; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin Receptor Agonists | 2006 |
A novel class of positive allosteric modulators of AMPA receptors: design, synthesis, and structure-activity relationships of 3-biphenyl-4-yl-4-cyano-5-ethyl-1-methyl-1H-pyrrole-2-carboxylic acid, LY2059346.
Topics: Allosteric Regulation; Carboxylic Acids; Cell Line; Drug Design; Excitatory Amino Acids; Glutamic Acid; Humans; Pyrroles; Receptors, AMPA; Structure-Activity Relationship; Transfection | 2006 |
Damipipecolin and damituricin, novel bioactive bromopyrrole alkaloids from the Mediterranean sponge Axinella damicornis.
Topics: Alkaloids; Animals; Axinella; Bromine; Calcium; Cell Survival; Cells, Cultured; Glutamic Acid; Humans; Mediterranean Region; Molecular Structure; N-Methylaspartate; Neurons; Pyrroles; Rats; Suberites | 2007 |
An enhanced biosensor for glutamate based on self-assembled carbon nanotubes and dendrimer-encapsulated platinum nanobiocomposites-doped polypyrrole film.
Topics: Biosensing Techniques; Dendrimers; Electrochemistry; Glutamate Dehydrogenase; Glutamic Acid; Nanocomposites; Nanoparticles; Nanotubes, Carbon; Platinum; Polyamines; Polymers; Pyrroles | 2007 |
Thrombin induces long-term potentiation of reactivity to afferent stimulation and facilitates epileptic seizures in rat hippocampal slices: toward understanding the functional consequences of cerebrovascular insults.
Topics: Afferent Pathways; Animals; Animals, Newborn; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Epilepsy; Glutamic Acid; Hemostatics; Hippocampus; Long-Term Potentiation; Male; Peptide Fragments; Potassium; Pyrroles; Quinazolines; Rats; Rats, Wistar; Receptor, PAR-1; Thrombin | 2008 |
Endocannabinoid-dependent plasticity at GABAergic and glutamatergic synapses in the striatum is regulated by synaptic activity.
Topics: Action Potentials; Animals; Arachidonic Acids; Calcium Channel Agonists; Calcium Channels, L-Type; Cannabinoid Receptor Modulators; Endocannabinoids; Female; gamma-Aminobutyric Acid; Glutamic Acid; Male; Neostriatum; Neuronal Plasticity; Neurons; Organ Culture Techniques; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Synapses; Synaptic Transmission | 2009 |
Estrogen attenuates glutamate-induced cell death by inhibiting Ca2+ influx through L-type voltage-gated Ca2+ channels.
Topics: Animals; Apoptosis; Calcium; Calcium Channel Agonists; Calcium Channels, L-Type; Calpain; Caspase 3; Cell Line; Cell Physiological Phenomena; Electric Capacitance; Estradiol; Estrogens; Glutamic Acid; Intracellular Space; Membrane Potentials; Mice; Neurons; Neuroprotective Agents; Pyrroles; Rats | 2009 |
Unraveling delta1-pyrroline-5-carboxylate-proline cycle in plants by uncoupled expression of proline oxidation enzymes.
Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Arabidopsis; Arabidopsis Proteins; Droughts; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Glutamic Acid; Hot Temperature; Medicago sativa; Mitochondria; Mutation; Nicotiana; Oxidation-Reduction; Plants; Plants, Genetically Modified; Proline; Proline Oxidase; Pyrroles; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Sodium Chloride | 2009 |
Highly sensitive and selective glutamate microbiosensor based on cast polyurethane/AC-electrophoresis deposited multiwalled carbon nanotubes and then glutamate oxidase/electrosynthesized polypyrrole/Pt electrode.
Topics: Biosensing Techniques; Conductometry; Electroplating; Enzymes, Immobilized; Equipment Design; Equipment Failure Analysis; Glutamic Acid; Microelectrodes; Miniaturization; Nanotubes, Carbon; Oxidoreductases; Platinum; Polymers; Polyurethanes; Pyrroles; Reproducibility of Results; Sensitivity and Specificity | 2010 |
Regulation of blood L-glutamate levels by stress as a possible brain defense mechanism.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adrenocorticotropic Hormone; Animals; Corticotropin-Releasing Hormone; Epinephrine; Glutamic Acid; Head Injuries, Closed; Hypothalamo-Hypophyseal System; Isoproterenol; Male; Pituitary-Adrenal System; Propranolol; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Corticotropin-Releasing Hormone; Stress, Physiological | 2010 |
Biocompatible molecularly imprinted polymers for the voltage regulated uptake and release of L-glutamate in neutral pH solutions.
Topics: Animals; Biocompatible Materials; Electrodes; Electromagnetic Fields; Glutamic Acid; Hydrogen-Ion Concentration; Materials Testing; Micro-Electrical-Mechanical Systems; Polymers; Pyrroles; Rats; Solutions; Surface Properties | 2010 |
Atorvastatin prevents hippocampal cell death, neuroinflammation and oxidative stress following amyloid-β(1-40) administration in mice: evidence for dissociation between cognitive deficits and neuronal damage.
Topics: Amino Acid Transport System X-AG; Amyloid beta-Peptides; Analysis of Variance; Animals; Animals, Newborn; Astrocytes; Atorvastatin; Cell Death; Cyclooxygenase 2; Encephalitis; Fluoresceins; Gene Expression Regulation; Glutamic Acid; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Heptanoic Acids; Hippocampus; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Learning Disabilities; Male; Maze Learning; Memory Disorders; Mice; Nerve Tissue Proteins; Neurons; Organic Chemicals; Oxidative Stress; Peptide Fragments; Propidium; Pyrroles; Tritium | 2010 |
Stress-induced priming of glutamate synapses unmasks associative short-term plasticity.
Topics: Animals; Biophysical Phenomena; Biophysics; Chelating Agents; Corticotropin-Releasing Hormone; Dizocilpine Maleate; Drug Interactions; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Exocytosis; Freezing Reaction, Cataleptic; Glutamic Acid; In Vitro Techniques; Male; Neuronal Plasticity; Neurons; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Pyrimidines; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; SNARE Proteins; Stress, Physiological; Synapses; Time Factors | 2010 |
Effect of enteropeptidase on survival of cultured hippocampal neurons under conditions of glutamate toxicity.
Topics: Animals; Cattle; Cell Survival; Cells, Cultured; Enteropeptidase; Glutamic Acid; Hippocampus; Humans; Neurons; Pyrroles; Quinazolines; Receptor, PAR-1; Recombinant Proteins; Thrombin | 2010 |
Idebenone inhibition of glutamate release from rat cerebral cortex nerve endings by suppression of voltage-dependent calcium influx and protein kinase A.
Topics: 4-Aminopyridine; Animals; Aspartic Acid; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Carbazoles; Cerebral Cortex; Clonazepam; Cyclic AMP-Dependent Protein Kinases; Dantrolene; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Indoles; Isoquinolines; Macrolides; Male; Maleimides; Membrane Potentials; Nerve Endings; omega-Conotoxins; Potassium; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Sprague-Dawley; Sodium-Calcium Exchanger; Sulfonamides; Synaptosomes; Thiazepines; Ubiquinone | 2011 |
Neurotoxic factors released by stimulated human monocytes and THP-1 cells.
Topics: Analysis of Variance; Antibodies; Cell Line, Transformed; Cell Line, Tumor; Cyclic N-Oxides; Cyclooxygenase 1; Cyclooxygenase 2; Cytokines; Dinoprostone; Dose-Response Relationship, Drug; Glutamate Decarboxylase; Glutamic Acid; Humans; Imidazoles; Interferon-gamma; L-Lactate Dehydrogenase; Leukemia, Monocytic, Acute; Lipopolysaccharides; Molecular Weight; Monocytes; NADPH Oxidases; Neurotoxins; Nitric Oxide Synthase Type I; Nitrites; Pyrroles; RNA, Messenger; Teratocarcinoma | 2011 |
5-HT(1B) receptors inhibit glutamate release from primary afferent terminals in rat medullary dorsal horn neurons.
Topics: Action Potentials; Afferent Pathways; Animals; Electrophysiological Phenomena; Glutamic Acid; Posterior Horn Cells; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B | 2012 |
Neuroprotection afforded by adenosine A2A receptor blockade is modulated by corticotrophin-releasing factor (CRF) in glutamate injured cortical neurons.
Topics: Adenosine A2 Receptor Antagonists; Animals; Cerebral Cortex; Corticotropin-Releasing Hormone; Glutamic Acid; Neural Inhibition; Neurons; Neuroprotective Agents; Primary Cell Culture; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Triazoles | 2012 |
The structure of (-)-kaitocephalin bound to the ligand binding domain of the (S)-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)/glutamate receptor, GluA2.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain; Crystallography, X-Ray; Glutamic Acid; Inhibitory Concentration 50; Ligands; Models, Chemical; Models, Molecular; Molecular Conformation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Pyrroles; Rats; Receptors, AMPA | 2012 |
Atorvastatin prevents cell damage via modulation of oxidative stress, glutamate uptake and glutamine synthetase activity in hippocampal slices subjected to oxygen/glucose deprivation.
Topics: Animals; Atorvastatin; Cell Death; Glucose; Glutamate-Ammonia Ligase; Glutamic Acid; Heptanoic Acids; Hippocampus; Male; Mice; Neurons; Neuroprotective Agents; Oxidative Stress; Oxygen; Pyrroles; Reactive Oxygen Species | 2013 |
Pyrroloquinoline quinine protects rat brain cortex against acute glutamate-induced neurotoxicity.
Topics: Animals; Apoptosis; Base Sequence; Cerebral Cortex; DNA Primers; Glutamic Acid; Glutathione; In Situ Nick-End Labeling; Male; Malondialdehyde; Nerve Tissue Proteins; Neuroprotective Agents; Phosphorylation; Pyrroles; Quinolines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; RNA, Messenger; Superoxide Dismutase | 2013 |
Δ(1)-pyrroline-5-carboxylate/glutamate biogenesis is required for fungal virulence and sporulation.
Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Ascomycota; Eleocharis; Fungal Proteins; Gene Deletion; Gene Expression Regulation, Fungal; Glutamic Acid; Phylogeny; Proline Oxidase; Pyrroles; Recombinant Proteins; Saccharomyces cerevisiae; Spores, Fungal; Virulence | 2013 |
Construction of glutamate biosensor based on covalent immobilization of glutamate oxidase on polypyrrole nanoparticles/polyaniline modified gold electrode.
Topics: Amino Acid Oxidoreductases; Aniline Compounds; Biosensing Techniques; Dielectric Spectroscopy; Enzymes, Immobilized; Food Analysis; Glutamic Acid; Gold; India; Microscopy, Electron, Scanning; Nanoparticles; Polymers; Pyrroles; X-Ray Diffraction | 2014 |
Stimulation of dopamine D4 receptors in the paraventricular nucleus of the hypothalamus of male rats induces hyperphagia: involvement of glutamate.
Topics: Animals; Benzamides; Corticosterone; Dopamine Agonists; Dopamine Antagonists; Drug Interactions; Eating; Fasting; GABA-A Receptor Agonists; Glutamic Acid; Hyperphagia; Male; Muscimol; Paraventricular Hypothalamic Nucleus; Piperazines; Pyridines; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptors, Dopamine D4; Satiation; Tritium | 2014 |
Identification of positive allosteric modulators VU0155094 (ML397) and VU0422288 (ML396) reveals new insights into the biology of metabotropic glutamate receptor 7.
Topics: Acetanilides; Animals; Benzoates; Calcium; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Glutamic Acid; Glycine; HEK293 Cells; Hippocampus; Humans; In Vitro Techniques; Male; Mice, Inbred C57BL; Picolinic Acids; Propionates; Pyrroles; Rats; Receptors, Metabotropic Glutamate; Structure-Activity Relationship; Thallium; Transfection | 2014 |
Atorvastatin prevents development of kindling by modulating hippocampal levels of dopamine, glutamate, and GABA in mice.
Topics: Animals; Anticonvulsants; Atorvastatin; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Heptanoic Acids; Hippocampus; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kindling, Neurologic; Male; Mice; Pyrroles; Seizures | 2015 |
An amperometric biosensor for L-glutamate determination prepared from L-glutamate oxidase immobilized in polypyrrole-polyvinylsulphonate film.
Topics: Amino Acid Oxidoreductases; Animals; Biosensing Techniques; Calibration; Cattle; Cross-Linking Reagents; Electrochemical Techniques; Electrodes; Enzymes, Immobilized; Glutamic Acid; Glutaral; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Polymers; Polyvinyls; Pyrroles; Sensitivity and Specificity; Serum Albumin, Bovine; Sulfonic Acids; Temperature | 2016 |
Grassland species differentially regulate proline concentrations under future climate conditions: an integrated biochemical and modelling approach.
Topics: Climate; Glutamic Acid; Grassland; Metabolic Networks and Pathways; Models, Biological; Monte Carlo Method; Ornithine; Proline; Pyrroles; RNA, Messenger; Species Specificity; Thermodynamics | 2015 |
Fabrication of Aligned Conducting PPy-PLLA Fiber Films and Their Electrically Controlled Guidance and Orientation for Neurites.
Topics: Animals; Electromagnetic Phenomena; Glutamic Acid; Neurites; PC12 Cells; Polymerization; Polymers; Pyrroles; Rats; Tissue Scaffolds | 2016 |
Vectorization of agrochemicals: amino acid carriers are more efficient than sugar carriers to translocate phenylpyrrole conjugates in the Ricinus system.
Topics: Agrochemicals; Amino Acids; Biological Transport; Fungicides, Industrial; Glucose; Glutamic Acid; Phloem; Pyrroles; Ricinus; Sugars; Triazoles | 2018 |
Effect of Class II HDAC inhibition on glutamate transporter expression and survival in SOD1-ALS mice.
Topics: Amino Acid Transport System X-AG; Amyotrophic Lateral Sclerosis; Animals; Astrocytes; Cells, Cultured; Excitatory Amino Acid Transporter 2; Female; Glutamic Acid; Histone Deacetylase Inhibitors; Histone Deacetylases; Hydroxamic Acids; Male; Mice, Transgenic; Pyrroles; Spinal Cord; Superoxide Dismutase-1 | 2017 |
Effects of introducing theanine or glutamic acid core to tralopyril on systemicity and insecticidal activity.
Topics: Animals; Glutamates; Glutamic Acid; Insecticides; Larva; Phloem; Pyrethrins; Pyrroles; Ricinus; Seedlings; Structure-Activity Relationship | 2017 |
Highly sensitive amperometric detection of glutamate by glutamic oxidase immobilized Pt nanoparticle decorated multiwalled carbon nanotubes(MWCNTs)/polypyrrole composite.
Topics: Biosensing Techniques; Dielectric Spectroscopy; Enzymes, Immobilized; Glutamic Acid; Humans; Limit of Detection; Nanocomposites; Nanoparticles; Nanotubes, Carbon; Oxidoreductases; Polymers; Pyrroles | 2019 |
Trypanosoma cruzi synthesizes proline via a Δ1-pyrroline-5-carboxylate reductase whose activity is fine-tuned by NADPH cytosolic pools.
Topics: Cytosol; Electron Transport; Glutamic Acid; Mitochondria; NADP; Oxidation-Reduction; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Trypanosoma cruzi | 2020 |
An interpenetrating and patternable conducting polymer hydrogel for electrically stimulated release of glutamate.
Topics: Gelatin; Glutamic Acid; Hydrogels; Polymers; Pyrroles | 2022 |
Protective Effects of Marine Alkaloid Neolamellarin A Derivatives against Glutamate Induced PC12 Cell Apoptosis.
Topics: Alkaloids; Animals; Antineoplastic Agents; Apoptosis; Glutamic Acid; PC12 Cells; Pyrroles; Rats | 2022 |