pyrroles has been researched along with etoposide in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 13 (65.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barrows, LR; Haughey, HM; Holden, JA; Ireland, CM; Matsumoto, SS; Schmehl, DM; Venables, DA | 1 |
| Campiani, G; Greene, LM; Lawler, M; Ledwidge, S; Mc Gee, MM; Nacci, V; Williams, DC; Zisterer, DM | 1 |
| Bae, JH; Chung, BS; Ju, DS; Kang, CD; Kim, DW; Kim, MJ; Kim, SH; Kwon, JK; Um, JH | 1 |
| Buchdunger, E; García-Echeverría, C; Hofmann, F; Krystal, GW; Litz, J; Warshamana-Greene, GS | 1 |
| Mistafa, O; Roudier, E; Stenius, U | 1 |
| Bortul, R; Evangelisti, C; Grafone, T; Martelli, AM; Martinelli, G; McCubrey, JA; Papa, V; Tabellini, G; Tazzari, PL | 1 |
| Dianov, GL; Fanta, M; Freschauf, GK; Grassot, JM; Hall, DG; Mani, RS; Mereniuk, TR; Virgen, CA; Weinfeld, M | 1 |
| Berger, M; Blackhall, F; Cummings, J; Dean, EJ; Dive, C; Ranson, M; Roulston, A | 1 |
| Daignault, S; Dy, GK; Gadgeel, SM; Kalemkerian, GP; Ramnath, N; Schneider, BJ; Wozniak, AJ | 1 |
| Högberg, J; Miraglia, E; Stenius, U | 1 |
| Berger, MS; Blakely, J; Chiappori, AA; Chu, QS; Moezi, MM; Ross, HJ; Salgia, R; Schnyder, J; Schreeder, MT; Stephenson, JJ; Subramaniam, DS | 1 |
| Couvelard, A; de Gramont, A; Faivre, S; Hammel, P; Neuzillet, C; Raymond, E; Serova, M; Tijeras-Raballand, A | 1 |
| Blow, JJ; Chadha, GS; Gillespie, PJ; Kaldis, P; Poh, WT | 1 |
| Fellowes, A; Hanna, DM; Hansford, JR; Mechinaud, F; Vedururu, R | 1 |
| Albert, I; Ao-Baslock, A; Berger, MS; Blakely, LJ; Kazarnowicz, A; Kovacs, P; Langer, CJ; Moezi, MM; Pajkos, G; Pathak, AK; Ross, HJ; Schnyder, J; Schreeder, MT; Somfay, A; Zatloukal, P | 1 |
| Baggstrom, M; Bogart, J; Crawford, J; Graziano, SL; Gu, L; Masters, GA; Miller, AA; Otterson, GA; Pang, HH; Ready, NE; Thomas, SP; Vokes, EE | 1 |
| Bogart, JA; Crawford, J; Gu, L; Pang, HH; Ready, NE; Salama, JK; Schild, SE; Vokes, EE; Wang, X | 1 |
| Coquel, F; Lin, YL; MacKeigan, JP; Pasero, P; Sasi, NK; Weinreich, M | 1 |
| Adler, S; Aljumaily, R; Antal, JM; Beck, JT; Boccia, RV; Bulat, I; Chiu, VK; Csoszi, T; Domine Gomez, M; Dragnev, KH; Hamm, JT; Hanna, W; Hart, LL; Hoyer, RJ; Hussein, MA; Lai, AY; Lowczak, A; Maglakelidze, M; Malik, RK; Morris, SR; Nikolinakos, P; Owonikoko, TK; Richards, DA; Roberts, PJ; Rocha Lima, CM; Sawrycki, P; Schuster, SR; Sorrentino, JA; Weiss, JM; Yang, Z | 1 |
1 review(s) available for pyrroles and etoposide
| Article | Year |
|---|---|
Resistance to targeted therapies in pancreatic neuroendocrine tumors (PNETs): molecular basis, preclinical data, and counteracting strategies.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Drug Resistance, Neoplasm; Etoposide; Everolimus; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Indoles; Medical Oncology; Neuroendocrine Tumors; Pancreatic Neoplasms; Pyrroles; Sirolimus; Sunitinib; TOR Serine-Threonine Kinases; Vascular Endothelial Growth Factor A | 2012 |
6 trial(s) available for pyrroles and etoposide
| Article | Year |
|---|---|
Phase II trial of sunitinib maintenance therapy after platinum-based chemotherapy in patients with extensive-stage small cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Early Termination of Clinical Trials; Etoposide; Female; Humans; Indoles; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Neovascularization, Pathologic; Patient Dropouts; Platinum; Pyrroles; Small Cell Lung Carcinoma; Sunitinib; Treatment Outcome | 2011 |
A phase I trial of pan-Bcl-2 antagonist obatoclax administered as a 3-h or a 24-h infusion in combination with carboplatin and etoposide in patients with extensive-stage small cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Central Nervous System; Drug Administration Schedule; Etoposide; Female; Humans; Indoles; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Small Cell Lung Carcinoma | 2012 |
Randomized phase II study of carboplatin and etoposide with or without obatoclax mesylate in extensive-stage small cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Comorbidity; Etoposide; Female; Humans; Indoles; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Pyrroles; Small Cell Lung Carcinoma; Treatment Outcome | 2014 |
Chemotherapy With or Without Maintenance Sunitinib for Untreated Extensive-Stage Small-Cell Lung Cancer: A Randomized, Double-Blind, Placebo-Controlled Phase II Study-CALGB 30504 (Alliance).
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Disease Progression; Disease-Free Survival; Double-Blind Method; Etoposide; Female; Humans; Indoles; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Proportional Hazards Models; Pyrroles; Small Cell Lung Carcinoma; Sunitinib; Treatment Outcome | 2015 |
Positive Interaction between Prophylactic Cranial Irradiation and Maintenance Sunitinib for Untreated Extensive-Stage Small Cell Lung Cancer Patients After Standard Chemotherapy: A Secondary Analysis of CALGB 30504 (ALLIANCE).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Cranial Irradiation; Disease-Free Survival; Etoposide; Female; Humans; Indoles; Lung Neoplasms; Maintenance Chemotherapy; Male; Middle Aged; Placebos; Pyrroles; Retrospective Studies; Small Cell Lung Carcinoma; Sunitinib | 2016 |
Myelopreservation with the CDK4/6 inhibitor trilaciclib in patients with small-cell lung cancer receiving first-line chemotherapy: a phase Ib/randomized phase II trial.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Cisplatin; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Double-Blind Method; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Myeloid Cells; Paclitaxel; Prognosis; Pyrimidines; Pyrroles; Small Cell Lung Carcinoma; Survival Rate; Tissue Distribution | 2019 |
13 other study(ies) available for pyrroles and etoposide
| Article | Year |
|---|---|
Makaluvamines vary in ability to induce dose-dependent DNA cleavage via topoisomerase II interaction.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; DNA; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; Humans; Mice; Mice, Nude; Nasopharyngeal Neoplasms; Pyrroles; Quinolones; Topoisomerase II Inhibitors | 1999 |
Selective induction of apoptosis by the pyrrolo-1,5-benzoxazepine 7-[[dimethylcarbamoyl]oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine (PBOX-6) in Leukemia cells occurs via the c-Jun NH2-terminal kinase-dependent phosphorylation and inactivation o
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Carbazoles; Dactinomycin; Drug Resistance, Neoplasm; Etoposide; Humans; Indoles; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; K562 Cells; Leukemia; Leukocytes, Mononuclear; Mitogen-Activated Protein Kinases; Oxazepines; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Subcellular Fractions; Tumor Cells, Cultured; Ultraviolet Rays | 2004 |
Relationship between antiapoptotic molecules and metastatic potency and the involvement of DNA-dependent protein kinase in the chemosensitization of metastatic human cancer cells by epidermal growth factor receptor blockade.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Line, Tumor; DNA-Activated Protein Kinase; DNA-Binding Proteins; Drug Synergism; Electrophoretic Mobility Shift Assay; ErbB Receptors; Etoposide; Genes, MDR; Humans; Indicators and Reagents; Melanoma; Neoplasm Metastasis; Nuclear Proteins; Protein Serine-Threonine Kinases; Pyrimidines; Pyrroles; Radiation-Sensitizing Agents; Rats | 2004 |
The insulin-like growth factor-I receptor kinase inhibitor, NVP-ADW742, sensitizes small cell lung cancer cell lines to the effects of chemotherapy.
Topics: Antineoplastic Agents; Apoptosis; Carboplatin; Carcinoma, Small Cell; Cell Division; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Etoposide; Gene Expression Regulation, Neoplastic; Humans; In Situ Nick-End Labeling; Insulin-Like Growth Factor I; Lung Neoplasms; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Receptor, IGF Type 1; RNA, Messenger; Vascular Endothelial Growth Factor A | 2005 |
Statins induce mammalian target of rapamycin (mTOR)-mediated inhibition of Akt signaling and sensitize p53-deficient cells to cytostatic drugs.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Atorvastatin; Carcinoma, Hepatocellular; Cell Proliferation; Chromones; Dose-Response Relationship, Drug; Etoposide; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver Neoplasms; Morpholines; Phosphorylation; Pravastatin; Protein Kinases; Proto-Oncogene Proteins c-akt; Pyrroles; Signal Transduction; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53 | 2006 |
The insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 induces apoptosis in acute myeloid leukemia cells exhibiting autocrine insulin-like growth factor-I secretion.
Topics: Apoptosis; Cyclin-Dependent Kinase Inhibitor p27; Cytarabine; Down-Regulation; Etoposide; HL-60 Cells; Humans; Insulin-Like Growth Factor I; Intracellular Signaling Peptides and Proteins; Leukemia, Myeloid, Acute; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Pyrimidines; Pyrroles; Receptor, IGF Type 1 | 2007 |
Mechanism of action of an imidopiperidine inhibitor of human polynucleotide kinase/phosphatase.
Topics: Adenosine Triphosphate; Antineoplastic Agents, Phytogenic; Binding Sites; Camptothecin; Cell Survival; Circular Dichroism; DNA Ligase ATP; DNA Ligases; DNA Polymerase beta; DNA Repair; DNA Repair Enzymes; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Fluorescence Resonance Energy Transfer; Humans; Lung Neoplasms; Mutagenesis, Site-Directed; Phosphotransferases (Alcohol Group Acceptor); Photoelectron Spectroscopy; Piperidines; Poly-ADP-Ribose Binding Proteins; Protein Conformation; Pyrroles; Radiation-Sensitizing Agents; Tumor Cells, Cultured; Xenopus Proteins | 2010 |
Optimization of circulating biomarkers of obatoclax-induced cell death in patients with small cell lung cancer.
Topics: Antineoplastic Agents; Biomarkers, Tumor; Blood Chemical Analysis; Calibration; Cell Death; Cell Line, Tumor; Cell Proliferation; Cisplatin; Clinical Trials, Phase I as Topic; Drug Synergism; Etoposide; Humans; Indoles; Lung Neoplasms; Prognosis; Pyrroles; Small Cell Lung Carcinoma | 2011 |
Statins exhibit anticancer effects through modifications of the pAkt signaling pathway.
Topics: Antineoplastic Agents; Atorvastatin; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; DNA Damage; Etoposide; Fluorouracil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Phosphatidylinositol 3-Kinases; Phosphoprotein Phosphatases; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Pyrroles; Receptors, Purinergic P2X; Signal Transduction | 2012 |
Xenopus Cdc7 executes its essential function early in S phase and is counteracted by checkpoint-regulated protein phosphatase 1.
Topics: Animals; Cell Cycle Proteins; CHO Cells; Chromatin; Cricetinae; Cricetulus; DNA Replication; Enzyme Inhibitors; Etoposide; Ovum; Phosphorylation; Piperidones; Protein Phosphatase 1; Protein Serine-Threonine Kinases; Pyrroles; S Phase Cell Cycle Checkpoints; Xenopus; Xenopus Proteins | 2014 |
A unique case of refractory primary mediastinal B-cell lymphoma with JAK3 mutation and the role for targeted therapy.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Female; Gene Expression Regulation, Neoplastic; Humans; Janus Kinase 3; Lymphoma, Large B-Cell, Diffuse; Mediastinal Neoplasms; Molecular Targeted Therapy; Mutation; Piperidines; Prednisone; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Signal Transduction; Stem Cell Transplantation; Transplantation, Homologous; Vincristine | 2014 |
DDK Has a Primary Role in Processing Stalled Replication Forks to Initiate Downstream Checkpoint Signaling.
Topics: Cell Cycle Proteins; Cell Line; Dimethyl Sulfoxide; DNA Repair Enzymes; DNA Replication; DNA, Single-Stranded; Etoposide; Exodeoxyribonucleases; Humans; Mitosis; Piperidones; Protein Serine-Threonine Kinases; Pyrimidinones; Pyrroles; Signal Transduction | 2018 |
Trilaciclib (Cosela) for prevention of chemotherapy-related myelosuppression.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Carcinoma, Non-Small-Cell Lung; Drug Interactions; Etoposide; Humans; Lung Neoplasms; Organoplatinum Compounds; Platinum Compounds; Pyrimidines; Pyrroles; Treatment Outcome | 2021 |