Compounds > pyrroles
Page last updated: 2024-08-18

pyrroles and etomidate

pyrroles has been researched along with etomidate in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's11 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cotten, JF; Cuny, GD; Forman, SA; Husain, SS; Kelly, EW; Laha, JK; Liu, A; Miller, KW; Nguyen, HH; Raines, DE; Stewart, D1
Banacos, N; Cotten, JF; Husain, SS; Le Ge, R; Pejo, E; Raines, DE; Williams, JH1
Cuny, GD; Laha, JK1
Chao, W; Cotten, JF; Feng, Y; Le Ge, R; Pejo, E; Raines, DE1
Cotten, JF; Cuny, GD; Kelly, EW; Laha, JK; Le Ge, R; Lin, XJ; Liu, J; Pejo, E; Raines, DE1
Jackson, WL1
Forman, SA; Pejo, E; Pierce, DW; Raines, DE1
Desai, R; Miller, KW; Raines, DE1
Bernhardt, R; Cotten, JF; Ge, R; Miller, KW; Neunzig, J; Raines, DE; Shanmugasundararaj, S; Zhou, X1
Husain, SS; Pejo, E; Raines, DE; Zhou, X1
Bertaccini, EJ; Cayla, NS; Dagne, BA; Davies, DL; Davies, MF; Gross, ER; Heifets, BD; Lu, Y; MacIver, MB; Rodriguez, L; Wu, Y1

Other Studies

11 other study(ies) available for pyrroles and etomidate

ArticleYear
Carboetomidate: a pyrrole analog of etomidate designed not to suppress adrenocortical function.
    Anesthesiology, 2010, Volume: 112, Issue:3

    Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Animals; Drug Design; Electrophysiology; Etomidate; Female; Hemodynamics; Hydrocortisone; Hypnotics and Sedatives; Larva; Male; Postural Balance; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger; Structure-Activity Relationship; Xenopus laevis

2010
Closed-loop continuous infusions of etomidate and etomidate analogs in rats: a comparative study of dosing and the impact on adrenocortical function.
    Anesthesiology, 2011, Volume: 115, Issue:4

    Topics: Adrenal Cortex; Animals; Biotransformation; Corticosterone; Depression, Chemical; Dose-Response Relationship, Drug; Electroencephalography; Etomidate; Hypnotics and Sedatives; Infusions, Intravenous; Male; Pyrroles; Rats; Rats, Sprague-Dawley

2011
Synthesis of fused imidazoles, pyrroles, and indoles with a defined stereocenter α to nitrogen utilizing Mitsunobu alkylation followed by palladium-catalyzed cyclization.
    The Journal of organic chemistry, 2011, Oct-21, Volume: 76, Issue:20

    Topics: Alkylation; Anxiety; Catalysis; Chemistry, Pharmaceutical; Cyclization; Etomidate; GABA Agonists; Humans; Hypnotics and Sedatives; Imidazoles; Indoles; Magnetic Resonance Spectroscopy; Molecular Structure; Nitrogen; Palladium; Pyrroles; Stereoisomerism; Structure-Activity Relationship

2011
Differential effects of etomidate and its pyrrole analogue carboetomidate on the adrenocortical and cytokine responses to endotoxemia.
    Critical care medicine, 2012, Volume: 40, Issue:1

    Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Cytokines; Dose-Response Relationship, Drug; Endotoxemia; Etomidate; Hypnotics and Sedatives; Interleukin-10; Interleukin-1beta; Interleukin-6; Male; Pyrroles; Rats; Rats, Sprague-Dawley

2012
In vivo and in vitro pharmacological studies of methoxycarbonyl-carboetomidate.
    Anesthesia and analgesia, 2012, Volume: 115, Issue:2

    Topics: Adrenal Cortex; Animals; Blood Pressure; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Stability; Etomidate; GABA-A Receptor Agonists; Hypnotics and Sedatives; Larva; Male; Membrane Potentials; Molecular Structure; Octanols; Patch-Clamp Techniques; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reflex; Structure-Activity Relationship; Time Factors; Water; Xenopus laevis

2012
Carboetomidate: will it eliminate the etomidate debate?
    Critical care medicine, 2012, Volume: 40, Issue:1

    Topics: Adrenocorticotropic Hormone; Animals; Cytokines; Endotoxemia; Etomidate; Hypnotics and Sedatives; Male; Pyrroles

2012
Carboetomidate inhibits alpha4/beta2 neuronal nicotinic acetylcholine receptors at concentrations affecting animals.
    Anesthesia and analgesia, 2012, Volume: 115, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Etomidate; Female; Humans; Hydrophobic and Hydrophilic Interactions; Hypnotics and Sedatives; Membrane Potentials; Nicotinic Antagonists; Olive Oil; Oocytes; Patch-Clamp Techniques; Plant Oils; Pyrroles; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Xenopus laevis

2012
The pyrrole etomidate analog carboetomidate potently inhibits human 5-HT3A receptor function: comparisons with etomidate and potential implications for emetogenesis.
    Anesthesia and analgesia, 2013, Volume: 116, Issue:3

    Topics: Etomidate; HEK293 Cells; Humans; Hypnotics and Sedatives; Pyrroles; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Antagonists

2013
Carboetomidate: an analog of etomidate that interacts weakly with 11β-hydroxylase.
    Anesthesia and analgesia, 2013, Volume: 116, Issue:6

    Topics: Binding Sites; Etomidate; Heme; Humans; Hydrocortisone; Pyrroles; Steroid 11-beta-Hydroxylase

2013
Sedative-hypnotic Binding to 11β-hydroxylase.
    Anesthesiology, 2016, Volume: 125, Issue:5

    Topics: Adrenal Cortex; Anesthetics, Dissociative; Animals; Etomidate; Hypnotics and Sedatives; Ketamine; Models, Animal; Propofol; Pyrroles; Rats; Rats, Sprague-Dawley; Steroid 11-beta-Hydroxylase; Structure-Activity Relationship

2016
A newly developed anesthetic based on a unique chemical core.
    Proceedings of the National Academy of Sciences of the United States of America, 2019, 07-30, Volume: 116, Issue:31

    Topics: Anesthetics; Animals; Drug Evaluation, Preclinical; Etomidate; GABA-A Receptor Agonists; Humans; Mice; Pyrroles; Rats; Receptors, GABA-A; Xenopus laevis

2019