pyrroles has been researched along with epidermal growth factor in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 19 (67.86) | 29.6817 |
| 2010's | 9 (32.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Freitas, F; Jeschke, M; Majstorovic, I; Mueller, DR; Schindler, P; Susa, M; Van Oostrum, J; Voshol, H | 1 |
| Kornilova, ES; Melikova, MS; Nikol'skiĭ, NN; Zheleznova, NN | 2 |
| Hynes, NE; Lane, HA; Motoyama, AB | 1 |
| Dagnaes-Hansen, F; Hynes, NE; Nexø, E; Sørensen, BS; Tørring, N | 1 |
| Abrahamsen, H; Andersson, Y; Christoffersen, T; Guren, TK; Susa, M; Thoresen, GH; Ødegård, J; Østby, E | 1 |
| Baker, C; Doucet, M; Fidler, IJ; Kim, SJ; Price, JE; Weber, KL | 1 |
| Coco, L; Dell'Era, P; Metra, M; Nicoli, S; Presta, M; Ronca, R | 1 |
| Bucana, CD; Fidler, IJ | 1 |
| Fidler, IJ; Yokoi, K | 1 |
| Matsumura, F; Park, S | 1 |
| Bergmann, S; Henklein, P; Hollenberg, MD; Junker, K; Kaufmann, R; Settmacher, U | 1 |
| Eggo, MC; Susarla, R; Watkinson, JC | 1 |
| Forsberg, S; Ostman, A; Rollman, O | 1 |
| Gettinger, S | 1 |
| Dolman, ME; Fretz, MM; Goldschmeding, R; Hennink, WE; Kok, RJ; Lacombe, M; Nguyen, TQ; Pato, J; Prakash, J; Storm, G | 1 |
| Cunningham, MP; Fan, Z; Green, M; Marks, C; Modjtahedi, H; Thomas, H | 1 |
| Iyengar, L; Lovicu, FJ; McAvoy, JW; Patkunanathan, B | 1 |
| Li, H; Niu, R; Wu, J; Wu, M; Ying, G; Zhang, B; Zhang, N | 1 |
| Boterberg, T; Casneuf, VF; Delrue, L; Demetter, P; Peeters, M; Van Damme, N | 1 |
| Crow, KR; Gakhar, G; Hua, DH; Nguyen, TA; Perchellet, EM; Perchellet, JP; Shi, A | 1 |
| Bos, EM; Henning, RH; Kloosterhuis, NJ; Leuvenink, HG; Melenhorst, WB; Mulder, GM; Nijboer, WN; Ploeg, RJ; Sandovici, M; Seelen, MA; Sunnarborg, SW; Trzpis, M; van Goor, H; Visser, L | 1 |
| Abouantoun, TJ; Castellino, RC; MacDonald, TJ | 1 |
| Camaioni, A; Mlynarcikova, A; Nagyova, E; Nemcova, L; Prochazka, R; Salustri, A; Scsukova, S | 1 |
| Arita, J; Iguchi, H; Ishida, M; Kanba, S; Mitsui, T | 1 |
| Bruns, CJ; Camaj, P; Gamba, S; Haertl, C; Heinemann, V; Jung, A; Laubender, RP; Modest, DP; Primo, S; Schwarz, B; Stintzing, S | 1 |
| Bracken, CP; Crampin, EJ; Cursons, J; Davis, MJ; Foroutan, M; Leuchowius, KJ; Redfern, A; Street, I; Thompson, EW; Tomaskovic-Crook, E; Waltham, M | 1 |
| Chang, H; Kim, HS; Kim, JW; Lee, JS; Moon, SU; Sung, JH | 1 |
1 review(s) available for pyrroles and epidermal growth factor
| Article | Year |
|---|---|
Targeted therapy in advanced non-small-cell lung cancer.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzenesulfonates; Bevacizumab; Carcinoma, Non-Small-Cell Lung; Drug Delivery Systems; Epidermal Growth Factor; Erlotinib Hydrochloride; Humans; Indoles; Lung Neoplasms; Niacinamide; Phenylurea Compounds; Piperidines; Protein Kinase Inhibitors; Pyridines; Pyrroles; Quinazolines; Signal Transduction; Sorafenib; Sunitinib; Treatment Outcome; Vascular Endothelial Growth Factor A | 2008 |
27 other study(ies) available for pyrroles and epidermal growth factor
| Article | Year |
|---|---|
Fluoroaluminate stimulates phosphorylation of p130 Cas and Fak and increases attachment and spreading of preosteoblastic MC3T3-E1 cells.
Topics: Aluminum; Amino Acid Sequence; Animals; Cell Adhesion; Cell Movement; Collagen; Crk-Associated Substrate Protein; Epidermal Growth Factor; Fluorine; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; GTP-Binding Proteins; Insulin; Lysophospholipids; Mice; Molecular Sequence Data; Osteoblasts; Pertussis Toxin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Pyrimidines; Pyrroles; Retinoblastoma-Like Protein p130; Signal Transduction; src-Family Kinases; Stem Cells; Tyrosine; Virulence Factors, Bordetella | 2002 |
[The role of Src-kinase in the regulation of endocytosis of EGF-receptor complexes. I. Dynamics of EGF internalization, recycling, sorting, and degradation during inhibition of Src-kinase activity].
Topics: Animals; Cell Line; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Kinetics; Mice; Mice, Knockout; Pyrimidines; Pyrroles; src-Family Kinases | 2001 |
[The role of Src-kinase in the regulation of endocytosis of EGF-receptor complexes. Distribution of clathrin after stimulation of EGR endocytosis in various cell lines during inhibition of Src-kinase activity].
Topics: Animals; Cell Line; Clathrin; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Fluorescent Antibody Technique, Direct; Humans; Mice; Mice, Knockout; Pyrimidines; Pyrroles; src-Family Kinases | 2001 |
The efficacy of ErbB receptor-targeted anticancer therapeutics is influenced by the availability of epidermal growth factor-related peptides.
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Betacellulin; Breast Neoplasms; Cell Division; Drug Interactions; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; G1 Phase; Growth Substances; Humans; Intercellular Signaling Peptides and Proteins; Ligands; Neuregulin-1; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Receptor, ErbB-2; Signal Transduction; Stomach Neoplasms; Substrate Specificity; Tumor Cells, Cultured | 2002 |
ErbB1 and prostate cancer: ErbB1 activity is essential for androgen-induced proliferation and protection from the apoptotic effects of LY294002.
Topics: Androgens; Apoptosis; Cell Division; Chromones; Drug Interactions; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Humans; Ligands; Male; Morpholines; Prostatic Neoplasms; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Tumor Cells, Cultured | 2003 |
EGF receptor-mediated, c-Src-dependent, activation of Stat5b is downregulated in mitogenically responsive hepatocytes.
Topics: Animals; Cell Division; Cells, Cultured; DNA; DNA-Binding Proteins; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Growth Hormone; Hepatocytes; Male; Milk Proteins; Mitogens; Phosphorylation; Phosphoserine; Phosphotyrosine; Prolactin; Protein Binding; Proto-Oncogene Proteins pp60(c-src); Pyrimidines; Pyrroles; Rats; Rats, Wistar; STAT5 Transcription Factor; Trans-Activators; Transforming Growth Factor alpha | 2003 |
Blockade of epidermal growth factor receptor signaling leads to inhibition of renal cell carcinoma growth in the bone of nude mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bone Neoplasms; Carcinoma, Renal Cell; Cell Division; Epidermal Growth Factor; ErbB Receptors; Humans; Kidney Neoplasms; Male; Mice; Mice, Nude; Paclitaxel; Phosphorylation; Pyrimidines; Pyrroles; Recombinant Proteins; Signal Transduction; Transforming Growth Factor alpha; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2003 |
Fibroblast growth factor receptor-1 is essential for in vitro cardiomyocyte development.
Topics: Animals; Butadienes; Cell Differentiation; Cell Size; Cells, Cultured; Embryo, Mammalian; Enzyme Inhibitors; Epidermal Growth Factor; Gene Expression; Homeobox Protein Nkx-2.5; Homeodomain Proteins; Mesoderm; Mice; Mice, Mutant Strains; Mitogen-Activated Protein Kinase Kinases; Myocytes, Cardiac; Myosin Heavy Chains; Nitriles; Protein-Tyrosine Kinases; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Signal Transduction; Stem Cells; Tetradecanoylphorbol Acetate; Transcription Factors; Xenopus Proteins | 2003 |
Bioassay using epidermal keratinocytes to determine phosphorylation status of the epidermal growth factor receptor in distant neoplasms.
Topics: Animals; Benzimidazoles; Biological Assay; Cell Line, Tumor; Dose-Response Relationship, Drug; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Fibrosarcoma; Keratinocytes; Mice; Mice, Inbred C3H; Microscopy, Fluorescence; Neoplasm Transplantation; Phosphorylation; Pyrimidines; Pyrroles; Specific Pathogen-Free Organisms | 2004 |
Hypoxia increases resistance of human pancreatic cancer cells to apoptosis induced by gemcitabine.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Blotting, Western; Butadienes; Cell Division; Cell Line, Tumor; Chromones; Deoxycytidine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Gemcitabine; Humans; Hypoxia; Mitogen-Activated Protein Kinases; Morpholines; Neovascularization, Pathologic; NF-kappa B; Nitriles; Oxygen; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Signal Transduction; Sp1 Transcription Factor; Time Factors; Tyrosine | 2004 |
Characterization of anti-apoptotic action of TCDD as a defensive cellular stress response reaction against the cell damaging action of ultra-violet irradiation in an immortalized normal human mammary epithelial cell line, MCF10A.
Topics: Adaptation, Physiological; alpha 1-Antitrypsin; Apoptosis; bcl-2-Associated X Protein; Benzoflavones; Butadienes; Cell Line; DNA Fragmentation; Epidermal Growth Factor; Epithelial Cells; Female; Ferric Compounds; Flavonoids; Glutathione; Humans; Hydrogen Peroxide; Lipopolysaccharides; Mitogen-Activated Protein Kinases; Nitriles; Nitro Compounds; Phenanthrolines; Polychlorinated Dibenzodioxins; Pyrimidines; Pyrroles; Quaternary Ammonium Compounds; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transforming Growth Factor alpha; Ultraviolet Rays | 2006 |
PAR-type thrombin receptors in renal carcinoma cells: PAR1-mediated EGFR activation promotes cell migration.
Topics: Cell Line, Tumor; Cell Movement; Dipeptides; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Humans; Kidney Neoplasms; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Oligopeptides; Phosphorylation; Pyrroles; Quinazolines; Receptor, PAR-1; Thrombin; Tyrosine; Tyrphostins | 2006 |
Regulation of plasminogen activators in human thyroid follicular cells and their relationship to differentiated function.
Topics: Adenylyl Cyclases; Aprotinin; Cell Differentiation; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activators; Epidermal Growth Factor; Fibroblast Growth Factors; Flavonoids; Humans; Indoles; Insulin; Iodine; Iodine Radioisotopes; Maleimides; Mesylates; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Plasminogen Inactivators; Protein Kinase C; Protein Kinase C beta; Protein Kinase Inhibitors; Pyrroles; RNA, Messenger; Serine Proteinase Inhibitors; Signal Transduction; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Time Factors; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator | 2007 |
Regeneration of human epidermis on acellular dermis is impeded by small-molecule inhibitors of EGF receptor tyrosine kinase.
Topics: Cell Proliferation; Cells, Cultured; Dermis; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; Epidermis; ErbB Receptors; Humans; Keratinocytes; Models, Biological; Organ Culture Techniques; Protein-Tyrosine Kinases; Psoriasis; Pyrimidines; Pyrroles; Receptor, ErbB-2; Regeneration | 2008 |
Intervention in growth factor activated signaling pathways by renally targeted kinase inhibitors.
Topics: Cells, Cultured; Chemistry, Pharmaceutical; Drug Carriers; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Erlotinib Hydrochloride; Fibrosis; Gene Expression Regulation; Humans; Intercellular Signaling Peptides and Proteins; Kidney Tubules, Proximal; Kinetics; Muramidase; Phosphorylation; Protein Kinase Inhibitors; Pyrazoles; Pyrroles; Quinazolines; Receptors, Transforming Growth Factor beta; Signal Transduction; Transforming Growth Factor beta | 2008 |
Co-targeting the EGFR and IGF-IR with anti-EGFR monoclonal antibody ICR62 and the IGF-IR tyrosine kinase inhibitor NVP-AEW541 in colorectal cancer cells.
Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Cell Proliferation; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Epidermal Growth Factor; ErbB Receptors; HCT116 Cells; Humans; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Receptor, IGF Type 1 | 2008 |
Growth factors involved in aqueous humour-induced lens cell proliferation.
Topics: Animals; Aqueous Humor; Cell Proliferation; Cells, Cultured; Epidermal Growth Factor; Epithelial Cells; Fibroblast Growth Factors; Insulin-Like Growth Factor I; Intercellular Signaling Peptides and Proteins; Lens, Crystalline; Platelet-Derived Growth Factor; Pyrroles; Quinazolines; Rats; Rats, Wistar; Signal Transduction; Tyrphostins | 2009 |
Screening of a PKC zeta-specific kinase inhibitor PKCzI257.3 which inhibits EGF-induced breast cancer cell chemotaxis.
Topics: Actins; Benzylamines; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Survival; Chemotaxis; Cofilin 1; Epidermal Growth Factor; Female; Humans; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles | 2010 |
Antiangiogenic versus cytotoxic therapeutic approaches in a mouse model of pancreatic cancer: an experimental study with a multitarget tyrosine kinase inhibitor (sunitinib), gemcitabine and radiotherapy.
Topics: Angiogenesis Inhibitors; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspase 3; Cell Line, Tumor; Chemotherapy, Adjuvant; Deoxycytidine; Epidermal Growth Factor; fas Receptor; Gemcitabine; Indoles; Male; Mice; Microvessels; Neovascularization, Pathologic; Pancreatic Neoplasms; Placenta Growth Factor; Pregnancy Proteins; Protein Kinase Inhibitors; Pyrroles; Radiotherapy, Adjuvant; Sunitinib; Time Factors; Vascular Endothelial Growth Factor A | 2009 |
Bioactivity and molecular targets of novel substituted quinolines in murine and human tumor cell lines in vitro.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; DNA; Epidermal Growth Factor; Ethidium; Gap Junctions; HSP90 Heat-Shock Proteins; Humans; Mice; Nucleosides; Pyrroles; Quinazolines; Quinolines; Signal Transduction | 2010 |
Heparin binding epidermal growth factor in renal ischaemia/reperfusion injury.
Topics: Adult; Aged; Animals; Cells, Cultured; Disease Models, Animal; Epidermal Growth Factor; Female; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Kidney; Kidney Transplantation; Male; Mice; Middle Aged; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Reperfusion Injury; RNA, Messenger; Up-Regulation; Young Adult | 2010 |
Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells.
Topics: Angiogenesis Inducing Agents; Animals; Antineoplastic Agents; Becaplermin; Cell Count; Cell Line, Tumor; Cell Movement; Cells, Cultured; Dose-Response Relationship, Drug; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Humans; Indoles; Medulloblastoma; Mice; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; PTEN Phosphohydrolase; Pyrroles; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Sunitinib; Time Factors | 2011 |
Activation of cumulus cell SMAD2/3 and epidermal growth factor receptor pathways are involved in porcine oocyte-cumulus cell expansion and steroidogenesis.
Topics: Animals; Benzamides; C-Reactive Protein; Cell Adhesion Molecules; Cumulus Cells; Dioxoles; Epidermal Growth Factor; ErbB Receptors; Female; Follicle Stimulating Hormone; Gene Expression Regulation, Developmental; Glucuronosyltransferase; Hyaluronic Acid; Isoquinolines; Meiosis; Mice; Oocytes; Progesterone; Pyridines; Pyrroles; Quinazolines; Serum Amyloid P-Component; Signal Transduction; Smad2 Protein; Smad3 Protein; Swine; Tyrphostins | 2011 |
cAMP response element-binding protein (CREB) is required for epidermal growth factor (EGF)-induced cell proliferation and serum response element activation in neural stem cells isolated from the forebrain subventricular zone of adult mice.
Topics: Animals; Blotting, Western; Carbazoles; Cell Growth Processes; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Epidermal Growth Factor; Female; Isoquinolines; Mice; Neural Stem Cells; Prosencephalon; Protein Kinase Inhibitors; Pyrroles; Serum Response Element; Sulfonamides; Transcriptional Activation | 2011 |
KRAS allel-specific activity of sunitinib in an isogenic disease model of colorectal cancer.
Topics: Alleles; Amino Acid Substitution; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Drug Resistance, Neoplasm; Epidermal Growth Factor; ets-Domain Protein Elk-1; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; Humans; Indoles; Inhibitory Concentration 50; Mutation; Phosphorylation; Proto-Oncogene Proteins p21(ras); Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; Sunitinib | 2013 |
Stimulus-dependent differences in signalling regulate epithelial-mesenchymal plasticity and change the effects of drugs in breast cancer cell lines.
Topics: Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Epidermal Growth Factor; Epithelial-Mesenchymal Transition; Everolimus; Female; Humans; Immunosuppressive Agents; Neoplasm Metastasis; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases | 2015 |
EGF Induced RET Inhibitor Resistance in CCDC6-RET Lung Cancer Cells.
Topics: Adenocarcinoma; Cell Line, Tumor; Cetuximab; Drug Resistance, Neoplasm; Epidermal Growth Factor; ErbB Receptors; fms-Like Tyrosine Kinase 3; Gefitinib; Gene Rearrangement; Hepatocyte Growth Factor; Humans; Indoles; Lung Neoplasms; MAP Kinase Signaling System; Mutation; Niacinamide; Phenylurea Compounds; Piperidines; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins c-ret; Pyrroles; Quinazolines; RNA, Small Interfering; Signal Transduction; Sorafenib; Sunitinib | 2017 |