Compounds > pyrroles
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pyrroles and duocarmycin b2

pyrroles has been researched along with duocarmycin b2 in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (66.67)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ichimura, M; Katsumata, S; Nakano, H; Ogawa, T; Takahashi, I; Takahashi, K1
Ichimura, M; Mihara, A; Nakano, H; Ogawa, T; Takahashi, I; Takahashi, K1
Gomi, K; Kobayashi, E; Nagamura, S; Saito, H1
Amishiro, N; Gomi, K; Kobayashi, E; Nagamura, S; Okamoto, A; Saito, H1
Amishiro, N; Gomi, K; Kobayashi, E; Nagamura, S; Okabe, M; Okamoto, A; Saito, H1
Searcey, M1

Reviews

1 review(s) available for pyrroles and duocarmycin b2

ArticleYear
Duocarmycins--natures prodrugs?
    Current pharmaceutical design, 2002, Volume: 8, Issue:15

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Cell Survival; DNA; Drug Stability; Duocarmycins; Indoles; Leucomycins; Leukemia L1210; Prodrugs; Pyrroles; Pyrrolidinones; Structure-Activity Relationship; Tumor Cells, Cultured

2002

Other Studies

5 other study(ies) available for pyrroles and duocarmycin b2

ArticleYear
Duocarmycins, new antitumor antibiotics produced by Streptomyces; producing organisms and improved production.
    The Journal of antibiotics, 1991, Volume: 44, Issue:10

    Topics: Antibiotics, Antineoplastic; Bromine; Carbon; Chlorine; Chromatography, High Pressure Liquid; Duocarmycins; Fermentation; Humans; Hydrogen-Ion Concentration; Indoles; Kinetics; Metals; Microscopy, Electron, Scanning; Nitrogen; Pyrroles; Pyrrolidinones; Streptomyces

1991
Interconversion and stability of duocarmycins, a new family of antitumor antibiotics: correlation to their cytotoxic and antimicrobial activities in vitro.
    Oncology research, 1993, Volume: 5, Issue:4-5

    Topics: 3T3 Cells; Animals; Antibiotics, Antineoplastic; Cell Division; Cell Line, Transformed; Drug Stability; Duocarmycins; Hydrogen-Ion Concentration; In Vitro Techniques; Indoles; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Pyrroles; Pyrrolidinones; Temperature

1993
Synthesis and antitumor activity of duocarmycin derivatives: A-ring pyrrole analogues of duocarmycin B2.
    Bioorganic & medicinal chemistry, 1996, Volume: 4, Issue:8

    Topics: Animals; Antibiotics, Antineoplastic; Duocarmycins; Female; Humans; Indoles; Mice; Pyrroles; Pyrrolidinones; Tumor Cells, Cultured; Uterine Neoplasms

1996
Synthesis and antitumor activity of duocarmycin derivatives: a-ring pyrrole compounds bearing 5-membered heteroarylacryloyl groups.
    Chemical & pharmaceutical bulletin, 1999, Volume: 47, Issue:10

    Topics: Acrylates; Animals; Antineoplastic Agents; Blood Cells; Combinatorial Chemistry Techniques; DNA; Duocarmycins; HeLa Cells; Humans; Indoles; Mice; Models, Chemical; Pyrroles; Pyrrolidinones; Sarcoma 180; Structure-Activity Relationship

1999
Synthesis and antitumor activity of duocarmycin derivatives: A-ring pyrrole compounds bearing beta-(5',6',7'-trimethoxy-2'-indolyl)acryloyl group.
    Bioorganic & medicinal chemistry, 2000, Volume: 8, Issue:7

    Topics: Animals; Antibiotics, Antineoplastic; Cell Division; Duocarmycins; HeLa Cells; Humans; Indoles; Inhibitory Concentration 50; Leukocyte Count; Male; Mice; Neoplasms, Experimental; Platelet Count; Pyrroles; Pyrrolidinones; Time Factors; Transplantation, Heterologous; Tumor Cells, Cultured

2000