Page last updated: 2024-08-18

pyrroles and d-alpha tocopherol

pyrroles has been researched along with d-alpha tocopherol in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.13)18.7374
1990's4 (10.26)18.2507
2000's22 (56.41)29.6817
2010's11 (28.21)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brooks, SK; Caasi, PI; Murty, HS; Nair, PP1
Mezey, E; Nair, PP; Quartner, J1
Bachorik, PS1
Althaus, JS; Fici, GJ; VonVoigtlander, PF1
Ewy, GA1
Joffe, BI; Kotze, MJ; Pilcher, GJ; Raal, FJ; Veller, MG1
Lemmens, PJ; Oranje, WA; Rondas-Colbers, GJ; Sels, JP; Wolffenbuttel, BH1
Bastagi, L; Boni, P; Massarelli, G; Muscari, A; Poggiopollini, G; Puddu, P; Tomassetti, V1
Guerrero, JM; Martínez-Cruz, F; Osuna, C1
Devaraj, S; Jialal, I; Venugopal, SK; Yang, T1
Dixon, JL; Shen, S; Sturek, M; Sun, GY; Vuchetich, JP; Wysocka, E1
Fujimura, M; Ichiishi, A; Motoyama, T; Ochiai, N; Oshima, M; Yamada-Okabe, H; Yamaguchi, I1
Aleo, E; Dmitrieva, A; Littarru, GP; Passi, S; Stancato, A1
Carlson, W; Clark, ME; Creager, M; Frei, B; Johnstone, M; Kinlay, S; Lloyd-Jones, DM; Maccallum, G; Orav, J; Rubenstein, J; Selwyn, AP; Sopko, G; Stone, PH1
De Leeuw, I; Manuel-Y-Keenoy, B; Van Gaal, L; Vertommen, J; Vinckx, M1
Ahotupa, M; Gylling, H; Miettinen, T; Nuotio, I; Strandberg, T; Tikkanen, MJ; Vanhanen, H; Vasankari, T; Viikari, J1
Andrews, TC; Carlson, W; Cole, H; Creager, MA; Frei, B; Johnstone, M; Kinlay, S; Lloyd-Jones, DM; Orav, J; Rubenstein, J; Selwyn, AP; Sopko, G; Stone, PH1
Bilo, HJ; Diepeveen, SH; Dikkeschei, LD; Kolsters, G; Offerman, JJ; Stalenhoef, AF; Van Der Palen, J; Van Tits, LJ; Verhoeven, GW1
Bitto, A; Bonaiuto, A; Bonaiuto, M; Campo, S; Castaldo, M; Cinquegrani, M; Saitta, A; Saitta, C; Sardo, MA; Trimarchi, G1
Arad, Y; Guerci, AD; Newstein, D; Roth, M; Spadaro, LA1
Antoniades, C; Pitsavos, C; Stefanadis, C; Tentolouris, C; Tousoulis, D; Toutouza, M; Trikas, A; Vassiliadou, C1
Antoniades, C; Stefanadis, C; Tousoulis, D1
Ray, DE; Willis, CL1
Antonini, R; Antonini, TM; Arca, M; Di Angelantonio, E; Diczfalusy, U; Iuliano, L; Micheletta, F; Montali, A; Natoli, S; Riggi, S1
Cangemi, R; Carnevale, R; Loffredo, L; Pignatelli, P; Violi, F1
Hidalgo, FJ; León, MM; Zamora, R1
Cangemi, R; Carnevale, R; Loffredo, L; Patrizi, MP; Perri, L; Pignatelli, P; Sanguigni, V; Violi, F1
Ariga, H; Iguchi-Ariga, S; Miyazaki, S; Nakano, M; Nunome, K1
Jin, H; Koo, PT; Tsang, DJ; Xiao, H; Yang, CS; Yang, Z1
Aydin, S; Coteli, E; Kara, H; Karatas, F; Servi, S1
Chang, LL; Chen, HW; Cheng, WL; Kuo, CL; Lii, CK; Liu, CS; Su, SL; Tsai, CW1
Abd-Elghany, MI; Heeba, GH1
Armstrong, JS; Hecht, SM; Khdour, OM; Lu, J1
Jeong, BS; Ku, JM; Nam, TG; Park, HG; Porter, NA1
Frank, J; Grebenstein, N; Hofmann, U; Podszun, MC1
Ichinomiya, S; Iwata, H; Sato, H; Siddig, S; Suwa, E; Tuerdi, G; Ueno, K; Yano, T1
Bergheim, I; Frank, J; Grebenstein, N; Kremoser, C; Podszun, MC; Schlueter, T; Spruss, A1
Chen, X; Li, Y; Meng, Q; Sun, H; Xu, P; Yin, Q; Yu, H; Zhang, Z1
Basu, S; Mallick, A; More, P; Syed, MM1

Trials

13 trial(s) available for pyrroles and d-alpha tocopherol

ArticleYear
Effect of atorvastatin on LDL oxidation and antioxidants in normocholesterolemic type 2 diabetic patients.
    Clinica chimica acta; international journal of clinical chemistry, 2001, Sep-25, Volume: 311, Issue:2

    Topics: Aged; Anticholesteremic Agents; Antioxidants; Atorvastatin; Blood Glucose; Cholesterol, LDL; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glycated Hemoglobin; Heptanoic Acids; Humans; Lipids; Male; Middle Aged; Oxidation-Reduction; Pyrroles; Ubiquinone; Vitamin E

2001
Short term effect of atorvastatin and vitamin E on serum levels of C3, a sensitive marker of the risk of myocardial infarction in men.
    Cardiovascular drugs and therapy, 2001, Volume: 15, Issue:5

    Topics: Anticholesteremic Agents; Antioxidants; Atorvastatin; Biomarkers; Cholesterol, HDL; Complement C3c; Double-Blind Method; Drug Therapy, Combination; Heptanoic Acids; Humans; Male; Middle Aged; Myocardial Infarction; Pyrroles; Risk Factors; Vitamin E

2001
Vascular basis for the treatment of myocardial ischemia study: trial design and baseline characteristics.
    American heart journal, 2004, Volume: 147, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Antioxidants; Ascorbic Acid; Atorvastatin; Brachial Artery; Cholesterol, LDL; Double-Blind Method; Female; Heptanoic Acids; Humans; Male; Middle Aged; Myocardial Ischemia; Pyrroles; Regional Blood Flow; Ultrasonography; Vasodilation; Vitamin E

2004
Impact of Vitamin E supplementation on lipoprotein peroxidation and composition in Type 1 diabetic patients treated with Atorvastatin.
    Atherosclerosis, 2004, Volume: 175, Issue:2

    Topics: Adult; Aged; alpha-Tocopherol; Antioxidants; Atorvastatin; Diabetes Mellitus, Type 1; Dietary Supplements; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Peroxidation; Lipoproteins; Male; Middle Aged; Pyrroles

2004
Effect of 12-month statin therapy on antioxidant potential of LDL and serum antioxidant vitamin concentrations.
    Annals of medicine, 2004, Volume: 36, Issue:8

    Topics: alpha-Tocopherol; Atorvastatin; beta Carotene; Cholesterol, LDL; Chromatography, High Pressure Liquid; Female; gamma-Tocopherol; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Pyrroles; Simvastatin

2004
Effect of intensive lipid lowering, with or without antioxidant vitamins, compared with moderate lipid lowering on myocardial ischemia in patients with stable coronary artery disease: the Vascular Basis for the Treatment of Myocardial Ischemia Study.
    Circulation, 2005, Apr-12, Volume: 111, Issue:14

    Topics: Angina Pectoris; Antioxidants; Ascorbic Acid; Atorvastatin; Coronary Artery Disease; Diet Therapy; Dose-Response Relationship, Drug; Exercise Test; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Metabolism; Lipids; Lipoproteins, LDL; Male; Myocardial Ischemia; Pyrroles; Vasomotor System; Vitamin E

2005
Effects of atorvastatin and vitamin E on lipoproteins and oxidative stress in dialysis patients: a randomised-controlled trial.
    Journal of internal medicine, 2005, Volume: 257, Issue:5

    Topics: Adult; alpha-Tocopherol; Apolipoproteins B; Atorvastatin; Cholesterol; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Failure, Chronic; Lipoproteins; Lipoproteins, LDL; Male; Middle Aged; Oxidative Stress; Peritoneal Dialysis; Pyrroles; Renal Dialysis; Statistics, Nonparametric; Triglycerides

2005
Antioxidant effect of atorvastatin is independent of PON1 gene T(-107)C, Q192R and L55M polymorphisms in hypercholesterolaemic patients.
    Current medical research and opinion, 2005, Volume: 21, Issue:5

    Topics: Anticholesteremic Agents; Aryldialkylphosphatase; Atorvastatin; Cholesterol, LDL; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Oxidation-Reduction; Placebos; Polymorphism, Genetic; Promoter Regions, Genetic; Pyrroles; Vitamin E

2005
Treatment of asymptomatic adults with elevated coronary calcium scores with atorvastatin, vitamin C, and vitamin E: the St. Francis Heart Study randomized clinical trial.
    Journal of the American College of Cardiology, 2005, Jul-05, Volume: 46, Issue:1

    Topics: Aged; alpha-Tocopherol; Antioxidants; Ascorbic Acid; Aspirin; Atorvastatin; Calcinosis; Coronary Artery Disease; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Platelet Aggregation Inhibitors; Pyrroles; Tomography, X-Ray Computed

2005
Effects of combined administration of low dose atorvastatin and vitamin E on inflammatory markers and endothelial function in patients with heart failure.
    European journal of heart failure, 2005, Volume: 7, Issue:7

    Topics: Aged; Antioxidants; Atorvastatin; Biomarkers; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endothelium, Vascular; Follow-Up Studies; Heart Failure; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-6; Male; Pyrroles; Treatment Outcome; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1; Vasodilation; Vitamin E

2005
Increased plasma levels of oxysterols, in vivo markers of oxidative stress, in patients with familial combined hyperlipidemia: reduction during atorvastatin and fenofibrate therapy.
    Free radical biology & medicine, 2007, Mar-01, Volume: 42, Issue:5

    Topics: Adult; alpha-Tocopherol; Atorvastatin; Biomarkers; Drug Combinations; Female; Fenofibrate; Heptanoic Acids; Humans; Hydroxycholesterols; Hyperlipidemia, Familial Combined; Hypolipidemic Agents; Ketocholesterols; Lipids; Lipoproteins; Male; Middle Aged; Models, Biological; Oxidative Stress; Pyrroles

2007
Early decrease of oxidative stress by atorvastatin in hypercholesterolaemic patients: effect on circulating vitamin E.
    European heart journal, 2008, Volume: 29, Issue:1

    Topics: Anticholesteremic Agents; Atorvastatin; Blood Platelets; Cholesterol, LDL; Cross-Sectional Studies; Dose-Response Relationship, Drug; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Isoprostanes; Male; Middle Aged; NADPH Oxidases; Oxidative Stress; Pyrroles; Superoxides; Vitamin E

2008
Atorvastatin increases blood ratios of vitamin E/low-density lipoprotein cholesterol and coenzyme Q10/low-density lipoprotein cholesterol in hypercholesterolemic patients.
    Nutrition research (New York, N.Y.), 2010, Volume: 30, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Deoxyguanosine; Erythrocytes; Female; Glutathione; Heptanoic Acids; Humans; Hypercholesterolemia; Lipids; Male; Middle Aged; Oxidative Stress; Pyrroles; Ubiquinone; Vitamin E

2010

Other Studies

26 other study(ies) available for pyrroles and d-alpha tocopherol

ArticleYear
Biosynthesis of heme in the vitamin E-deficient rat.
    The Journal of biological chemistry, 1970, Oct-25, Volume: 245, Issue:20

    Topics: Acyltransferases; Adenosine Triphosphatases; Amino Acids; Animals; Bone Marrow; Carbon Isotopes; Catalase; Cytochromes; Glucosephosphate Dehydrogenase; Glycine; Heme; Hydro-Lyases; Isocitrate Dehydrogenase; Levulinic Acids; Liver; Malate Dehydrogenase; Male; Microsomes, Liver; Oxidoreductases; Propionates; Pyrroles; Rats; Succinates; Tryptophan Oxygenase; Vitamin E; Vitamin E Deficiency

1970
The effect of vitamin E on porphyrinuria induced by ethanol in the rat.
    Biochemical medicine, 1971, Volume: 5, Issue:1

    Topics: 5-Aminolevulinate Synthetase; Acyltransferases; Amines; Animals; Cytochromes; Ethanol; Fasting; Hydro-Lyases; Levulinic Acids; Male; Microsomes, Liver; Porphyrias; Porphyrins; Propionates; Pyrroles; Rats; Succinates; Sucrose; Vitamin E

1971
Therapy and clinical trials.
    Current opinion in lipidology, 1998, Volume: 9, Issue:5

    Topics: Antioxidants; Arteriosclerosis; Atorvastatin; Clinical Trials as Topic; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Pyrroles; Vitamin A; Vitamin E

1998
Pharmacological approaches to counter the toxicity of Dopa.
    Amino acids, 1998, Volume: 14, Issue:1-3

    Topics: Animals; Benzothiazoles; Cells, Cultured; Cerebellum; Cytoplasmic Granules; Glutathione; Levodopa; Neuroprotective Agents; Pramipexole; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Selegiline; Thiazoles; Vitamin E

1998
Antioxidant therapy for coronary artery disease: don't paint the walls without treating the termites!
    Archives of internal medicine, 1999, Jun-28, Volume: 159, Issue:12

    Topics: Angioplasty, Balloon, Coronary; Anticholesteremic Agents; Antioxidants; Atorvastatin; Cholesterol, LDL; Coronary Disease; Heptanoic Acids; Humans; Lung Neoplasms; Oxidation-Reduction; Prospective Studies; Pyrroles; Randomized Controlled Trials as Topic; Risk; Survival Analysis; Treatment Outcome; Vitamin A; Vitamin E

1999
Efficacy of vitamin E compared with either simvastatin or atorvastatin in preventing the progression of atherosclerosis in homozygous familial hypercholesterolemia.
    The American journal of cardiology, 1999, Dec-01, Volume: 84, Issue:11

    Topics: Adolescent; Adult; Anticholesteremic Agents; Arteriosclerosis; Atorvastatin; Carotid Arteries; Child; Child, Preschool; Cholesterol, HDL; Cholesterol, LDL; Disease Progression; DNA; Female; Heptanoic Acids; Homozygote; Humans; Hyperlipoproteinemia Type II; Male; Mutation; Pyrroles; Receptors, LDL; Simvastatin; Treatment Outcome; Triglycerides; Tunica Intima; Vitamin E

1999
Melatonin prevents the formation of pyrrolized proteins in human plasma induced by hydrogen peroxide.
    Neuroscience letters, 2002, Jul-05, Volume: 326, Issue:3

    Topics: Antioxidants; Ascorbic Acid; Blood Proteins; Dose-Response Relationship, Drug; Humans; Hydrogen Peroxide; Melatonin; Oxidants; Oxidative Stress; Pyrroles; Vitamin E

2002
Alpha-tocopherol decreases superoxide anion release in human monocytes under hyperglycemic conditions via inhibition of protein kinase C-alpha.
    Diabetes, 2002, Volume: 51, Issue:10

    Topics: Acetophenones; alpha-Tocopherol; Antioxidants; Biphenyl Compounds; Cell Line; Ellagic Acid; Enzyme Activation; Enzyme Inhibitors; Humans; Hyperglycemia; Isoenzymes; Mesylates; Monocytes; NADPH Oxidases; Oligodeoxyribonucleotides, Antisense; Onium Compounds; Phosphoproteins; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Pyrroles; Superoxides

2002
Increased atherosclerosis in diabetic dyslipidemic swine: protection by atorvastatin involves decreased VLDL triglycerides but minimal effects on the lipoprotein profile.
    Journal of lipid research, 2002, Volume: 43, Issue:10

    Topics: Animals; Anticholesteremic Agents; Arteriosclerosis; Atorvastatin; Blood Glucose; Cholesterol; Collagen; Diabetes Mellitus, Experimental; Diet, Atherogenic; Fasting; Heptanoic Acids; Hyperlipidemias; Insulin; Lipoproteins, VLDL; Liver; Male; Pyrroles; Swine; Swine, Miniature; Triglycerides; Vitamin A; Vitamin E

2002
Effects of iprodione and fludioxonil on glycerol synthesis and hyphal development in Candida albicans.
    Bioscience, biotechnology, and biochemistry, 2002, Volume: 66, Issue:10

    Topics: Aminoimidazole Carboxamide; Antioxidants; Candida albicans; Culture Media; Dioxoles; Fungicides, Industrial; Glycerol; Histidine Kinase; Hydantoins; Hyphae; Microbial Sensitivity Tests; Pesticide Synergists; Piperonyl Butoxide; Protein Kinases; Pyrroles; Saccharomyces cerevisiae; Vitamin E

2002
Statins lower plasma and lymphocyte ubiquinol/ubiquinone without affecting other antioxidants and PUFA.
    BioFactors (Oxford, England), 2003, Volume: 18, Issue:1-4

    Topics: Antioxidants; Atorvastatin; Catalase; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Coenzymes; Erythrocytes; Fatty Acids, Unsaturated; Glutathione; Glutathione Peroxidase; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Lymphocytes; Male; Middle Aged; Pravastatin; Pyrroles; Simvastatin; Superoxide Dismutase; Ubiquinone; Vitamin E

2003
Statins and antioxidant vitamins: should co-administration be avoided?
    Journal of the American College of Cardiology, 2006, Mar-21, Volume: 47, Issue:6

    Topics: Antioxidants; Ascorbic Acid; Atorvastatin; Calcinosis; Cardiovascular Diseases; Coronary Disease; Drug Therapy, Combination; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pyrroles; Vitamin E

2006
Antioxidants attenuate MK-801-induced cortical neurotoxicity in the rat.
    Neurotoxicology, 2007, Volume: 28, Issue:1

    Topics: Animals; Antioxidants; Cell Death; Cerebral Cortex; Cerebrovascular Circulation; Cyclic N-Oxides; Dimethyl Sulfoxide; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Free Radical Scavengers; Neurons; Oxidative Stress; Pyrroles; Rats; Rats, Inbred F344; Vitamin E

2007
Statins enhance circulating vitamin E.
    International journal of cardiology, 2008, Jan-11, Volume: 123, Issue:2

    Topics: Atorvastatin; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Metabolic Syndrome; Middle Aged; Oxidative Stress; Pyrroles; Retrospective Studies; Simvastatin; Vitamin E

2008
Effect of tocopherols in the antioxidative activity of oxidized lipid-amine reaction products.
    Journal of agricultural and food chemistry, 2007, May-30, Volume: 55, Issue:11

    Topics: alpha-Tocopherol; Antioxidants; Gas Chromatography-Mass Spectrometry; Lipids; Lysine; Olive Oil; Phosphatidylethanolamines; Phosphatidylserines; Plant Oils; Pyrroles

2007
Pyrroloquinoline quinone prevents oxidative stress-induced neuronal death probably through changes in oxidative status of DJ-1.
    Biological & pharmaceutical bulletin, 2008, Volume: 31, Issue:7

    Topics: Animals; Antioxidants; Ascorbic Acid; Blotting, Western; Cell Death; Cell Survival; Dose-Response Relationship, Drug; Female; Hydrogen Peroxide; Microtubule-Associated Proteins; Neurons; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxidopamine; Pregnancy; Protein Binding; Protein Deglycase DJ-1; Pyrroles; Quinolines; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vitamin E

2008
Synergistic actions of atorvastatin with gamma-tocotrienol and celecoxib against human colon cancer HT29 and HCT116 cells.
    International journal of cancer, 2010, Feb-15, Volume: 126, Issue:4

    Topics: Atorvastatin; Celecoxib; Cell Cycle; Cell Division; Cell Line, Tumor; Chromans; Colonic Neoplasms; Cyclooxygenase 2 Inhibitors; Drug Synergism; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Polyisoprenyl Phosphates; Pyrazoles; Pyrroles; Sulfonamides; Vitamin E

2010
Effect of 3-(1H-Pyrrol-2-yl)-1H-indazole on the antioxidant status of rats.
    Biological trace element research, 2010, Volume: 136, Issue:1

    Topics: Animals; Antioxidants; Ascorbic Acid; Free Radicals; Glutathione Peroxidase; Indazoles; Kidney; Liver; Male; Malondialdehyde; Pyrroles; Rats; Rats, Wistar; Selenium; Vitamin A; Vitamin E

2010
Effect of combined administration of ginger (Zingiber officinale Roscoe) and atorvastatin on the liver of rats.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2010, Dec-01, Volume: 17, Issue:14

    Topics: Animals; Anti-Inflammatory Agents; Anticholesteremic Agents; Antioxidants; Atorvastatin; Catalase; Chemical and Drug Induced Liver Injury; Cholesterol; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Heptanoic Acids; Liver; Male; Malondialdehyde; Nitric Oxide; Phytotherapy; Plant Extracts; Pyrroles; Random Allocation; Rats; Rats, Wistar; Rhizome; Superoxide Dismutase; Transaminases; Vitamin E; Zingiber officinale

2010
Design, synthesis, and evaluation of an α-tocopherol analogue as a mitochondrial antioxidant.
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: alpha-Tocopherol; Animals; Antioxidants; Cattle; Cell Membrane; Diterpenes; Drug Design; Lipid Peroxidation; Mitochondria; Pyridines; Pyrimidines; Pyrroles; Reactive Oxygen Species

2010
New synthetic route to N-tocopherol derivatives: synthesis of pyrrolopyridinol analogue of α-tocopherol from pyridoxine.
    Organic & biomolecular chemistry, 2011, Mar-21, Volume: 9, Issue:6

    Topics: alpha-Tocopherol; Hydroxylation; Molecular Structure; Pyridines; Pyridoxine; Pyrroles; Stereoisomerism

2011
High-dose supplementation with natural α-tocopherol does neither alter the pharmacodynamics of atorvastatin nor its phase I metabolism in guinea pigs.
    Toxicology and applied pharmacology, 2013, Feb-01, Volume: 266, Issue:3

    Topics: alpha-Tocopherol; Animals; Anticholesteremic Agents; Atorvastatin; Blotting, Western; Cholesterol; Cytochrome P-450 CYP3A; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Guinea Pigs; Heptanoic Acids; Liver; Pyrroles; Random Allocation

2013
Synergistic effect of combined treatment with gamma-tocotrienol and statin on human malignant mesothelioma cells.
    Cancer letters, 2013, Oct-01, Volume: 339, Issue:1

    Topics: Apoptosis; Atorvastatin; Caspase 3; Cell Line, Tumor; Cell Proliferation; Chromans; Drug Synergism; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Enzyme Activation; Heptanoic Acids; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mesothelioma; Metabolic Networks and Pathways; Mevalonic Acid; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Simvastatin; Vitamin E

2013
Dietary α-tocopherol and atorvastatin reduce high-fat-induced lipid accumulation and down-regulate CD36 protein in the liver of guinea pigs.
    The Journal of nutritional biochemistry, 2014, Volume: 25, Issue:5

    Topics: alpha-Tocopherol; Animals; Anticholesteremic Agents; Atorvastatin; CD36 Antigens; Dietary Supplements; Down-Regulation; Guinea Pigs; Heptanoic Acids; Lipid Metabolism; Liver; Oxidative Stress; Pyrroles; Receptors, LDL; Triglycerides; Ubiquitination

2014
Hydrogen-bonded and reduction-responsive micelles loading atorvastatin for therapy of breast cancer metastasis.
    Biomaterials, 2014, Volume: 35, Issue:26

    Topics: Animals; Atorvastatin; Breast; Breast Neoplasms; Cell Line, Tumor; Delayed-Action Preparations; Female; Heptanoic Acids; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; Micelles; Oxidation-Reduction; Polyethylene Glycols; Pyrroles; Vitamin E

2014
Nanoparticle-Mediated Mitochondrial Damage Induces Apoptosis in Cancer.
    ACS applied materials & interfaces, 2016, Jun-01, Volume: 8, Issue:21

    Topics: alpha-Tocopherol; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Drug Carriers; HeLa Cells; Humans; Indoles; Mitochondria; Nanoparticles; Organophosphorus Compounds; Pyrroles

2016