pyrroles has been researched along with cyclopentane in 58 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (36.21) | 18.7374 |
| 1990's | 4 (6.90) | 18.2507 |
| 2000's | 12 (20.69) | 29.6817 |
| 2010's | 20 (34.48) | 24.3611 |
| 2020's | 1 (1.72) | 2.80 |
| Authors | Studies |
|---|---|
| Levy, J; Malaisse, WJ | 1 |
| Armstrong, JM; Barras, M; Hicks, PE; Lawson, K; Martin, DJ; Zazzi-Sudriez, E | 1 |
| Chapman, ID; Mazzoni, L; Morley, J | 1 |
| Vainer, H; Verry, M | 1 |
| Devis, G; Malaisse, WJ; Malaisse-Lagae, F; Ravazzola, M; Somers, G; Van Obberghen, E | 1 |
| Dechavanne, M; Desnoyers, P; Stoltz, JF; Vainer, H; Verry, M | 1 |
| Mahy, M; Malaisse, WJ; Pipeleers, DG | 1 |
| DeBernardis, JF; Siuda, JF | 1 |
| Riveline, B | 1 |
| Leclercq-Meyer, V; Malaisse, WJ | 1 |
| Plauchu, M; Pousset, G | 1 |
| Masbernard, A; Portal, A | 1 |
| Simonin, R | 1 |
| Desnoyers, P; Verry, M | 1 |
| Bergi, L; Boulanger, M; Duhault, J; Tisserand, F | 1 |
| Duhault, J; Lebon, F | 1 |
| Anstett, M; Desnoyers, P; Herrera, M; Labaume, J; Pesquet, J; Sebastien, J | 1 |
| Bour, H; Denard, Y; Plauchu, M; Rathery, M; Simonin, R; Thervet, F; Warembourg, H | 1 |
| Frisch, SB; Kaszynski, E | 1 |
| Arcamone, F; Casazza, AM; Chandra, P; Di Marco, A; Fioretti, A; Ghione, M; Götz, A; Verini, MA; Wacker, A; Zumino, F | 1 |
| Baker, AD; Betteridge, D; Kemp, NR; Kirby, RE | 1 |
| Bell, MR; Bradford, JC; Gelotte, KO; Hlavac, AG; McGarry, RH; Oesterlin, R; Rozitis, J | 1 |
| Chapman, ID; Cook, NS | 1 |
| Harrington, PE; Tius, MA | 1 |
| Cantin, LD; Griffin, AM; Hanessian, S | 1 |
| Acquotti, D; Auzzas, L; Battistini, L; Casiraghi, G; Marzocchi, L; Pinna, L; Rassu, G; Zanardi, F | 1 |
| Baurin, N; Chavatte, P; Lesieur, D; Marot, C; Yous, S | 1 |
| Daly, CJ; McGrath, JC | 1 |
| Baker, JG; Hall, IP; Hill, SJ | 1 |
| Fujioka, H; Futamura, J; Ganesh, JK; Kita, Y; Ohba, Y; Sawama, Y | 1 |
| Basosi, R; Busi, E; Elisei, F; Fusi, S; Latterini, L; Migani, A; Olivucci, M; Pepi, A; Ponticelli, F; Sampedro, D; Zanirato, V | 1 |
| Brummond, KM; Curran, DP; Fischer, S; Mitasev, B | 1 |
| Ney, JE; Wolfe, JP | 1 |
| Dong, G; Trost, BM | 1 |
| Atkinson, S; Brown, SH; Chessell, IP; Chowdhury, A; Clayton, NM; Coleman, T; Giblin, GM; Gleave, RJ; Hall, A; Hammond, B; Healy, MP; Johnson, MR; Michel, AD; Naylor, A; Novelli, R; Spalding, DJ; Tang, SP | 1 |
| Abu Thaher, B; Koch, P; Laufer, S; Schattel, V | 1 |
| David Tingley, F; Deninno, SL; Drozda, SE; Lowe, JA; Sanner, M; Schmidt, CJ; Tunucci, D; Valentine, J; Ward, KM | 1 |
| Li, Q; Yu, ZX | 1 |
| Lau, KC; Lo, PK | 1 |
| Al-Amin, M; Maeyama, Y; Shishido, K; Yoshida, M | 1 |
| Chen, D; Lu, N; Meng, L; Zhang, G | 1 |
| Hanessian, S | 1 |
| Ferrence, GM; Lammer, AD; Lash, TD | 1 |
| Balamurugan, R; Gudla, V | 1 |
| Frederich, JH; Harran, PG | 1 |
| Cai, C; Hou, C; Johnson, D; McComsey, DF; McKenney, S; O'Neill, JC; Opas, E; Sui, Z | 1 |
| Ehmke, V; Trost, BM | 1 |
| Bruchim, I; Flescher, E; Reiss, A; Sarfstein, R; Werner, H | 1 |
| Briddon, SJ; Gherbi, K; Hill, SJ | 1 |
| Zhang, Q; Zhao, G; Zhou, H | 1 |
| Baker, JG; Briddon, SJ; Gherbi, K; Hill, SJ; May, LT | 1 |
| Bao, W; Mou, XQ; Wang, J; Wang, SH; Xu, ZL; Yang, C; Zhang, D; Zhou, SJ; Zhu, DY | 1 |
| Lee, D; Lee, H; Sun, C | 1 |
| Du, ZY; Liu, WF; Liu, WT; Mou, XQ; Sheng, ZJ; Wang, SH; Xi, QM; Xu, XT; Zhang, K; Zhao, SQ; Zheng, X | 1 |
| Mikami, Y; Murofushi, T; Suzuki, N; Tsuda, H; Yamaguchi, Y | 1 |
| Kazemi Chegeni, Z; Soleymani, M | 1 |
| Flores-Martínez, YA; Le-Trilling, VTK; Trilling, M | 1 |
2 review(s) available for pyrroles and cyclopentane
| Article | Year |
|---|---|
Naturally occurring halogenated organic compounds.
Topics: Alkaloids; Amino Acids; Animals; Anthraquinones; Bromine; Coumarins; Cyclopentanes; Esters; Fluorine; Griseofulvin; Halogens; Hydrocarbons, Halogenated; Indoles; Iodine; Ketones; Lipids; Phenols; Pyrroles; Quinones; Spiro Compounds; Terpenes; Tetracycline; Tyrosine; Xanthenes | 1973 |
The enterprise of synthesis: from concept to practice.
Topics: Amides; Amino Acids; Biological Products; Cyclopentanes; Glycosides; History, 20th Century; History, 21st Century; Indoles; Macrolides; Oligopeptides; Pyrans; Pyrroles; Stereoisomerism; Terpenes | 2012 |
1 trial(s) available for pyrroles and cyclopentane
| Article | Year |
|---|---|
[Long term study of a new antidiabetic agent in 1183 cases].
Topics: Administration, Oral; Adult; Aged; Clinical Trials as Topic; Cyclopentanes; Diabetes Mellitus; Diabetic Angiopathies; Drug Evaluation; Female; Follow-Up Studies; Humans; Hypoglycemic Agents; Male; Middle Aged; Pyrroles; Sulfonylurea Compounds | 1974 |
55 other study(ies) available for pyrroles and cyclopentane
| Article | Year |
|---|---|
The stimulus-secretion coupling of glucose-induced insulin release-XVII. Effects of sulfonylureas and diazoxide on insular biosynthetic activity.
Topics: Animals; Cyclohexanes; Cyclopentanes; Diazoxide; Glucose; Hormones; In Vitro Techniques; Insulin; Islets of Langerhans; Leucine; Oxidation-Reduction; Peptide Biosynthesis; Proinsulin; Pyrazines; Pyrroles; Rats; Sulfonylurea Compounds; Tolbutamide | 1975 |
Differential effects of endothelin-1 on the vasorelaxant properties of benzopyran and non-benzopyran potassium channel openers.
Topics: Animals; Aorta; Benzopyrans; Cromakalim; Cyclopentanes; Dihydropyridines; Dose-Response Relationship, Drug; Endothelins; Guanidines; Hypertension; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Pinacidil; Potassium Channels; Pyridines; Pyrroles; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Vasodilation; Vasodilator Agents | 1992 |
Actions of SDZ PCO 400 and cromakalim on airway smooth muscle in vivo.
Topics: Animals; Benzopyrans; Bronchodilator Agents; Cromakalim; Cyclopentanes; Eosinophilia; Guinea Pigs; Male; Muscle, Smooth; Pyrroles; Respiratory Hypersensitivity; Respiratory System; Respiratory Tract Diseases | 1991 |
[The "in vitro" effect of gliclazide, a new hypoglycemic agent, on normal human blood platelets].
Topics: Blood Platelets; Carbon Radioisotopes; Cyclopentanes; Diabetes Mellitus; Enzyme Repression; Glycogen; Glycogen Synthase; Humans; Hypoglycemic Agents; In Vitro Techniques; Pyrroles; Sulfonylurea Compounds | 1974 |
Dynamics of insulin release and microtubular-microfilamentous system. IV. Effect of colchicine upon sulphonylurea-induced insulin secretion.
Topics: Animals; Colchicine; Cyclopentanes; Drug Synergism; Hypoglycemic Agents; Insulin; Insulin Secretion; Microtubules; Pancreas; Perfusion; Pyrroles; Rats; Stimulation, Chemical; Sulfonylurea Compounds; Time Factors | 1974 |
[Effect of gliclazide on platelet behavior].
Topics: Adenylyl Cyclases; Blood Glucose; Blood Platelets; Carbon Radioisotopes; Cyclopentanes; Diabetes Mellitus; Diabetic Angiopathies; Humans; Hypoglycemic Agents; Platelet Adhesiveness; Pyrroles; Sulfonylurea Compounds; Tritium; Ultracentrifugation | 1974 |
The stimulus-secretion coupling of glucose-induced insulin release. XII. Effects of diazoxide and gliclazide upon 45 calcium efflux from perifused islets.
Topics: Animals; Calcium; Calcium Isotopes; Cell Membrane Permeability; Cyclopentanes; Deuterium; Diazoxide; Extracellular Space; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Oxides; Perfusion; Pyrroles; Rats; Sulfonylurea Compounds | 1973 |
Insulinotropic action of a new sulfonylurea: gliclazide.
Topics: Animals; Cyclopentanes; Diabetic Angiopathies; Dogs; Drug Interactions; Fatty Acids, Nonesterified; Glucose; Glyburide; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Secretion; Pancreas; Pyrroles; Rats; Sulfonylurea Compounds | 1972 |
[Gliclazide, a new antidiabetic with hemobiologic and vascular properties].
Topics: Adult; Aged; Cyclopentanes; Diabetes Mellitus; Female; Humans; Hypoglycemic Agents; Male; Middle Aged; Pyrroles; Sulfonylurea Compounds | 1972 |
[The real problem in diabetes (trial of gliclazide, an original molecule with metabolic and vascular properties)].
Topics: Aged; Cyclopentanes; Diabetes Mellitus; Diabetic Angiopathies; Female; Humans; Hypoglycemic Agents; Male; Microcirculation; Middle Aged; Pyrroles; Sex Factors; Sulfonylurea Compounds; Time Factors | 1972 |
[Study on Gliclazide, an antidiabetic with a double vascular and metabolic polarity].
Topics: Adult; Aged; Cyclopentanes; Diabetes Mellitus; Diabetic Angiopathies; Female; Humans; Hypoglycemic Agents; Male; Middle Aged; Pyrroles; Sulfonylurea Compounds | 1972 |
Measure of platelet stickiness: the glass beads retention test in animal and human being.
Topics: Animals; Blood Cell Count; Blood Coagulation Tests; Blood Platelets; Carotid Arteries; Catheterization; Cyclopentanes; Diabetes Mellitus; Dogs; Drug Evaluation, Preclinical; Femoral Artery; Glass; Guinea Pigs; In Vitro Techniques; Methods; Platelet Adhesiveness; Propionates; Pyrroles; Rabbits; Rats; Salicylates; Species Specificity; Sulfonylurea Compounds; Time Factors; Veins | 1972 |
The pharmacology of S 1702, a new highly effective oral antibiabetic drug with unusual properties. 1. Pharmacological and hypoglycaemic activity, studies in different animal species.
Topics: Administration, Oral; Animals; Blood Glucose; Chemical Phenomena; Chemistry; Cyclopentanes; Dogs; Fatty Acids, Nonesterified; Glucose Tolerance Test; Guinea Pigs; Hypoglycemia; Hypoglycemic Agents; Injections, Intravenous; Insulin; Insulin Secretion; Lethal Dose 50; Male; Mice; Pyrroles; Rabbits; Rats; Sulfonylurea Compounds; Tolbutamide | 1972 |
The pharmacology of S 1702, a new highly effective oral antidiabetic drug with unusual properties. 2. Protective activity of S 1702 on the microvascular system in normal and diabetic rats.
Topics: Animals; Blood Coagulation Tests; Capillaries; Capillary Permeability; Cyclopentanes; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Hypoglycemic Agents; Male; Mesentery; Pyrroles; Rats; Skin; Sulfonylurea Compounds; Thrombosis | 1972 |
The pharmacology S 1702, a new highly effective oral antidiabetic drug with unusual properties. 3. Antistickiness activity, fibrinolytic properties and haemostatic parameters study.
Topics: Administration, Oral; Animals; Capillary Permeability; Cyclopentanes; Dogs; Fibrinolysis; Hypoglycemic Agents; Injections; Male; Plasminogen; Platelet Adhesiveness; Pyrroles; Rabbits; Rats; Sulfonylurea Compounds; Time Factors | 1972 |
[Diamicron].
Topics: Animals; Blood Coagulation; Blood Glucose; Cyclopentanes; Diabetes Mellitus; Humans; Hypoglycemic Agents; Pyrroles; Rats; Sulfonylurea Compounds; Vasomotor System | 1972 |
[A new antidiabetic agent: glyclazide. A study of glycemic regulation].
Topics: Adult; Aged; Blood Glucose; Cyclopentanes; Diabetes Mellitus; Female; Gluconeogenesis; Glycolysis; Glycosuria; Humans; Hypoglycemic Agents; Male; Middle Aged; Obesity; Pyrroles; Statistics as Topic; Sulfonylurea Compounds; Time Factors | 1974 |
Mouse foot screen for the inhibition of sweating by anticholinergic drugs.
Topics: Animals; Cyclohexanes; Cyclopentanes; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Hindlimb; Hydroxyzine; Injections, Subcutaneous; Male; Methods; Mice; Parasympatholytics; Pilocarpine; Propanolamines; Propylamines; Pyrroles; Quaternary Ammonium Compounds; Scopolamine; Sweating | 1974 |
Some structural requirements for the antibiotic action of distamycins, 3. Possible interaction of formyl group of distamycin side chain with adenine.
Topics: Adenine Nucleotides; Amidines; Anti-Bacterial Agents; Chromatography, DEAE-Cellulose; Cyclopentanes; DNA; Formates; Peptides; Polynucleotides; Propionates; Protein Biosynthesis; Pyrroles; RNA; RNA Nucleotidyltransferases; RNA, Ribosomal; Structure-Activity Relationship; Templates, Genetic; Vaccinia virus | 1972 |
Application of photoelectron spectrometry to pesticide analysis. Photoelectron spectra of five-membered heterocycles and related molecules.
Topics: Bridged-Ring Compounds; Cyclopentanes; Furans; Oxazoles; Pesticides; Photometry; Pyrazoles; Pyrroles; Spectrum Analysis; Thiophenes | 1970 |
Experimental antiulcer drugs.4. 1,3-Disubstituted 2,4,5,6-tetrahydro-4,6,6 -trimethyl-2-phenylcyclopenta[c]pyrrole-4-carboxamides.
Topics: Animals; Anti-Ulcer Agents; Cyclopentanes; Dogs; Gastric Juice; Haplorhini; Hematologic Diseases; Mice; Pyrroles; Rats; Structure-Activity Relationship | 1980 |
Therapeutic potential of potassium channel openers in peripheral vascular disease and asthma.
Topics: Animals; Asthma; Benzopyrans; Cromakalim; Cyclopentanes; Disease Models, Animal; Humans; Parasympatholytics; Peripheral Vascular Diseases; Potassium Channels; Pyrroles; Rats | 1993 |
A formal total synthesis of roseophilin: cyclopentannelation approach to the macrocyclic core.
Topics: Cyclopentanes; Heterocyclic Compounds, 3-Ring; Oxidation-Reduction; Pyrroles; Streptomyces | 1999 |
Asymmetric synthesis of functionalized carbocycles and heterocycles.
Topics: Chemistry; Cinnamates; Cyclohexanes; Cyclopentanes; Furans; Hydrocarbons; Models, Chemical; Molecular Conformation; Pyrroles; Stereoisomerism | 2000 |
Variable strategy toward carbasugars and relatives. 1. Stereocontrolled synthesis of pseudo-beta-D-gulopyranose, pseudo-beta-D-xylofuranose, (pseudo-beta-D-gulopyranosyl)amine, and (pseudo-beta-D-xylofuranosyl)amine.
Topics: Carbohydrates; Cyclohexanes; Cyclopentanes; Furans; Molecular Conformation; Molecular Mimicry; Pyrroles; Stereoisomerism | 2000 |
Three-dimensional quantitative structure-activity relationships of cyclo-oxygenase-2 (COX-2) inhibitors: a comparative molecular field analysis.
Topics: Benzene Derivatives; Binding Sites; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cyclopentanes; Imidazoles; Isoenzymes; Isoxazoles; Models, Molecular; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Pyrroles; Quantitative Structure-Activity Relationship; Spiro Compounds; Thiophenes | 2001 |
Do fluorescent drugs show you more than you wanted to know?
Topics: Adrenergic beta-2 Receptor Agonists; Animals; Boron Compounds; Cyclopentanes; Fluorescent Dyes; Humans; Ligands; Pyrroles; Receptors, Adrenergic, beta-2 | 2003 |
Pharmacology and direct visualisation of BODIPY-TMR-CGP: a long-acting fluorescent beta2-adrenoceptor agonist.
Topics: Adrenergic beta-2 Receptor Agonists; Alkaline Phosphatase; Animals; Binding Sites; Boron Compounds; CHO Cells; Cricetinae; Cyclic AMP; Cyclopentanes; GPI-Linked Proteins; Humans; Isoenzymes; Ligands; Microscopy, Confocal; Pyrroles; Receptors, Adrenergic, beta-2; Response Elements; Transcription, Genetic | 2003 |
The rearrangement of 2,3-epoxysulfonates and its application to natural products syntheses: formal synthesis of (-)-aphanorphine and total syntheses of (-)-alpha-herbertenol and (-)-herbertenediol.
Topics: Alkaloids; Biological Products; Bridged-Ring Compounds; Cyclopentanes; Epoxy Compounds; Indicators and Reagents; Magnetic Resonance Spectroscopy; Molecular Conformation; Phenols; Pyrroles; Sulfonic Acids | 2003 |
Design and photochemical characterization of a biomimetic light-driven Z/E switcher.
Topics: Biomimetic Materials; Cyclopentanes; Imines; Isomerism; Models, Molecular; Molecular Conformation; Photochemistry; Pyrroles; Rhodopsin; Schiff Bases; Thermodynamics | 2004 |
Heterocyclic alpha-alkylidene cyclopentenones obtained via a Pauson-Khand reaction of amino acid derived allenynes. A scope and limitation study directed toward the preparation of a tricyclic pyrrole library.
Topics: Alkynes; Amino Acids; Cyclopentanes; Heterocyclic Compounds; Molecular Conformation; Pyrroles | 2005 |
Selective synthesis of 5- or 6-aryl octahydrocyclopenta[b]pyrroles from a common precursor through control of competing pathways in a Pd-catalyzed reaction.
Topics: Catalysis; Cyclopentanes; Ligands; Organometallic Compounds; Palladium; Pyrroles; Structure-Activity Relationship | 2005 |
New class of nucleophiles for palladium-catalyzed asymmetric allylic alkylation. Total synthesis of agelastatin A.
Topics: Alkaloids; Alkylation; Allyl Compounds; Amides; Catalysis; Cyclopentanes; Oxazolidinones; Palladium; Pyrroles; Stereoisomerism | 2006 |
Structure-activity relationships of 1,5-biaryl pyrroles as EP1 receptor antagonists.
Topics: Analgesics; Animals; Benzoates; Biological Availability; Cyclohexanes; Cyclopentanes; Inflammation; Ligands; Pain; Pyrroles; Rats; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Structure-Activity Relationship | 2006 |
Role of the hydrogen bonding heteroatom-Lys53 interaction between the p38alpha mitogen-activated protein (MAP) kinase and pyridinyl-substituted 5-membered heterocyclic ring inhibitors.
Topics: Cyclopentanes; Furans; Hydrogen Bonding; Imidazoles; Mitogen-Activated Protein Kinase 14; Pyridines; Pyrroles; Structure-Activity Relationship; Thermodynamics | 2009 |
An octahydro-cyclopenta[c]pyrrole series of inhibitors of the type 1 glycine transporter.
Topics: Animals; Cell Line; Cyclopentanes; Dogs; Glycine Plasma Membrane Transport Proteins; Humans; Microsomes; Pyrroles | 2010 |
Conjugated diene-assisted allylic C-H bond activation: cationic Rh(I)-catalyzed syntheses of polysubstituted tetrahydropyrroles, tetrahydrofurans, and cyclopentanes from ene-2-dienes.
Topics: Alkadienes; Allyl Compounds; Catalysis; Cations; Cyclization; Cyclopentanes; Furans; Molecular Structure; Pyrroles; Rhodium; Stereoisomerism | 2010 |
High-level ab initio predictions for the ionization energies and heats of formation of five-membered-ring molecules: thiophene, furan, pyrrole, 1,3-cyclopentadiene, and borole, C4H4X/C4H4X+ (X = S, O, NH, CH2, and BH).
Topics: Cations; Computational Biology; Cyclopentanes; Electrons; Energy Transfer; Furans; Hot Temperature; Hydrogen; Models, Molecular; Molecular Structure; Pyrroles; Quantum Theory; Thermodynamics; Thiophenes; Vibration | 2011 |
Synthesis of substituted 1,4,5,6-tetrahydrocyclopenta[b]pyrroles by platinum-catalyzed cascade cyclization/ring expansion of 2-alkynyl-1-azaspiro[2.3]hexanes.
Topics: Catalysis; Cyclization; Cyclopentanes; Hexanes; Molecular Structure; Platinum; Pyrroles; Spiro Compounds; Stereoisomerism | 2011 |
Enantioselectivity in organocatalytic cascade double Michael addition reaction: a theoretical study.
Topics: Amines; Catalysis; Cyclization; Cyclopentanes; Electrons; Imidazoles; Imines; Models, Molecular; Models, Theoretical; Molecular Structure; Pyrroles; Quantum Theory; Stereoisomerism; Thermodynamics | 2012 |
Two-step synthesis of stable dioxadicarbaporphyrins from bis(3-indenyl)methane.
Topics: Crystallography, X-Ray; Cyclopentanes; Indenes; Methane; Molecular Conformation; Porphyrins; Pyrroles; Spectrophotometry, Ultraviolet | 2012 |
Synthesis of 1-arylnaphthalenes by gold-catalyzed one-pot sequential epoxide to carbonyl rearrangement and cyclization with arylalkynes.
Topics: Alkynes; Catalysis; Cyclization; Cyclopentanes; Epoxy Compounds; Furans; Gold; Naphthalenes; Pyrans; Pyrroles; Stereoisomerism | 2013 |
Modular access to complex prodiginines: total synthesis of (+)-roseophilin via its 2-azafulvene prototropisomer.
Topics: Aza Compounds; Cyclopentanes; Heterocyclic Compounds, 3-Ring; Molecular Structure; Pyrroles; Stereoisomerism | 2013 |
Discovery and SAR of 5-aminooctahydrocyclopentapyrrole-3a-carboxamides as potent CCR2 antagonists.
Topics: Cyclopentanes; Dose-Response Relationship, Drug; Drug Discovery; Humans; Molecular Conformation; Pyrroles; Receptors, CCR2; Structure-Activity Relationship | 2014 |
An approach for rapid increase in molecular complexity: atom economic routes to fused polycyclic ring systems.
Topics: Alkynes; Catalysis; Cyclization; Cyclopentanes; Ligands; Methane; Molecular Structure; Palladium; Polycyclic Compounds; Pyrroles; Stereoisomerism | 2014 |
IGF1R tyrosine kinase inhibitor enhances the cytotoxic effect of methyl jasmonate in endometrial cancer.
Topics: Acetates; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cyclopentanes; Dose-Response Relationship, Drug; Endometrial Neoplasms; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Oxylipins; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Receptor, IGF Type 1; Time Factors | 2014 |
Detection of the secondary, low-affinity β1 -adrenoceptor site in living cells using the fluorescent CGP 12177 derivative BODIPY-TMR-CGP.
Topics: Adrenergic beta-1 Receptor Agonists; Animals; Boron Compounds; CHO Cells; Cricetulus; Cyclic AMP; Cyclopentanes; Fluorescent Dyes; Genes, Reporter; Humans; Membrane Proteins; Propanolamines; Pyrroles; Receptors, Adrenergic, beta-1; Response Elements | 2014 |
Synthesis of cyclopentenes, pyrroles, and thiophenes via a sequence of propargyl-allenyl isomerizations, michael additions, and intramolecular Wittig reactions.
Topics: Catalysis; Cyclization; Cyclopentanes; Isomerism; Molecular Structure; Pargyline; Pyrroles; Stereoisomerism; Thiophenes | 2014 |
Negative cooperativity across β1-adrenoceptor homodimers provides insights into the nature of the secondary low-affinity CGP 12177 β1-adrenoceptor binding conformation.
Topics: Adrenergic beta-Antagonists; Animals; Binding Sites; Boron Compounds; CHO Cells; Cricetinae; Cricetulus; Cyclopentanes; Humans; Kinetics; Ligands; Mutagenesis, Site-Directed; Propanolamines; Protein Conformation; Protein Multimerization; Protein Structure, Quaternary; Pyrroles; Receptors, Adrenergic, beta-1; Recombinant Proteins | 2015 |
An Au(I)-catalyzed rearrangement/cyclization cascade toward the synthesis of 2-substituted-1,4,5,6-tetrahydrocyclopenta[b]pyrrole.
Topics: Amines; Catalysis; Cyclization; Cyclobutanes; Cyclopentanes; Gold; Pyrroles | 2015 |
Synthesis of the Carbocyclic Core of Massadine.
Topics: Cyclization; Cyclopentanes; Molecular Structure; Pyrroles; Stereoisomerism | 2015 |
Anti-inflammatory activity effect of 2-substituted-1,4,5,6-tetrahydrocyclopenta[b]pyrrole on TPA-induced skin inflammation in mice.
Topics: Animals; Anti-Inflammatory Agents; Cyclopentanes; Dermatitis; Mice; NF-kappa B; Pyrroles; Tetradecanoylphorbol Acetate | 2016 |
CAY10591, a SIRT1 activator, suppresses cell growth, invasion, and migration in gingival epithelial carcinoma cells.
Topics: Cell Division; Cell Line, Tumor; Cyclopentanes; Dimethyl Sulfoxide; Gingival Neoplasms; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; Pyrroles; Quinoxalines; Reverse Transcriptase Polymerase Chain Reaction; Sirtuin 1 | 2017 |
A molecular electron density theory study on the [3+2] cycloaddition reaction of 5,5-dimethyl-1-pyrroline N-oxide with 2-cyclopentenone.
Topics: Cycloaddition Reaction; Cyclopentanes; Density Functional Theory; Electrons; Models, Molecular; Molecular Structure; Pyrroles; Stereoisomerism | 2019 |
Nedd8-Activating Enzyme Is a Druggable Host Dependency Factor of Human and Mouse Cytomegalovirus.
Topics: Animals; Antiviral Agents; Cell Line; Cell Line, Tumor; Cullin Proteins; Cyclopentanes; Cytomegalovirus; Host Microbial Interactions; Humans; Mice; Muromegalovirus; NEDD8 Protein; Protein Processing, Post-Translational; Proteome; Pyrimidines; Pyrroles; Ubiquitin-Activating Enzymes; Ubiquitin-Protein Ligases | 2021 |