pyrroles has been researched along with cyclin d1 in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (12.50) | 29.6817 |
| 2010's | 20 (83.33) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Anderson, BA; Brooks, HB; Campbell, RM; Considine, E; DeHahn, TB; Dempsey, JA; Faul, MM; Kumrich, CA; Li, T; Ogg, CA; Paal, M; Patel, BK; Sanchez-Martinez, C; Schultz, RM; Shih, C; Somoza, C; Spencer, CD; Wagner, J; Watkins, SA; Winneroski, LL; Xun, Z; Zhu, G | 1 |
| Al-awar, RS; Clayton, MT; Coffey, DS; Engler, TA; Faul, MM; Furness, K; Grutsch, JL; Kolis, SP; LeTourneau, M; Malhotra, S; Martinelli, MJ; Pawlak, JM; Pedersen, SW; Ray, JE; Sullivan, KA | 1 |
| Li, H; Weinstein, IB | 1 |
| DeCastro, A; Janakiram, NB; Lee, HJ; Paul, S; Rao, CV; Reddy, BS; Simi, B; Smolarek, AK; So, JY; Steele, V; Suh, N; Wang, CX | 1 |
| Celano, M; D'Agostino, M; Durante, C; Filetti, S; Maggisano, V; Moretti, S; Puxeddu, E; Russo, D; Sponziello, M; Verrienti, A; Voce, P | 1 |
| Anzini, M; Belmonte, G; Biava, M; Cappelli, A; Cervellati, F; Di Capua, A; Giordani, A; Maioli, E; Sticozzi, C; Valacchi, G | 1 |
| Bydlowski, SP; Chierice, GO; Ferreira, AK; Filho, OM; Freitas, VM; Levy, D; Maria, DA; Rici, RE; Ruiz, JL | 1 |
| Chumduri, C; Daniel, PT; Dörken, B; Müller, A; Scholz, CW; Zang, C | 1 |
| Banerjee, P; Begum, S; Castellanos, MR; Debata, PR; Genzer, O; Kleiner, MJ; Mata, A | 1 |
| Basolo, F; Bocci, G; Borrelli, N; Canu, B; Danesi, R; Di Desidero, T; Fioravanti, A; Fontanini, G; Francia, G; Giannini, R; Kerbel, RS; Man, S; Orlandi, P; Xu, P | 1 |
| Chang, LS; Chen, CY; Chung, MI; Hsiao, CT; Hsu, CC; Hu, WP; Lee, PH; Lin, YT; Lin, YY; Wang, JJ; Yu, WT | 1 |
| Cohen, O; Cohen, ZR; Gorshtein, A; Hadani, M; Kammer, A; Rubinfeld, H; Shimon, I; Werner, H | 1 |
| Cantoni, S; Galiè, N; Galletti, M; Mai, A; Manes, A; Palazzini, M; Pasquinelli, G; Valente, S; Ventura, C; Zambelli, F | 1 |
| Elssner, C; Jaeger, D; Kautz, N; Koehler, BC; Lorenz, S; Scherr, AL; Schulze-Bergkamen, H; Urbanik, T; Welte, S | 1 |
| Chung, YM; Han, S; Kim, BH; Lee, H; Lee, HG; Park, CH; Shin, K; Ye, SK | 1 |
| Choudhury, D; Fujiwara, K; Fukuda, N; Grandori, C; Igarashi, J; Ikeda, M; Kawashima, H; Kemp, CJ; Kimura, MT; Kobayashi, Y; Koshikawa, N; Koshinaga, T; Kusafuka, T; Mishra, R; Nagase, H; Nemoto, N; Ohira, M; Soma, M; Takeuchi, J; Uekusa, S; Verma, NK; Wang, X; Watanabe, T | 1 |
| Bujak, A; Dymek, B; Dzwonek, K; Grygielewicz, P; Gunerka, P; Lamparska-Przybysz, M; Pietrucha, T; Stanczak, A; Turowski, P; Wieczorek, M | 1 |
| Byun, YS; Choi, KC; Go, RE; Jeon, SY; Jeung, EB; Kim, CW; Nam, KH | 1 |
| Afshar, M; Bardoli, AD; Miscoria, M; Pirrie, S; Porfiri, E; Stubbs, C; Wheeley, I | 1 |
| Chang, CC; Chang, Y; Cheung, MW; Ho, C; Huang, CP; Lee, WC; Lin, WC; Or, CR; Su, HL | 1 |
| Cai, D; Chen, Q; Li, M; Wu, X | 1 |
| Ghosh, PM; Sam, A; Steele, TM; Talbott, GC; Tepper, CG; Vinall, RL | 1 |
| Choi, KC; Hwang, KA; Lee, GH | 1 |
| Chen, H; Chen, P; Cheng, G; Fan, J; He, L; Hong, J; Hu, K; Jiang, Y; Li, J; Lin, L; Lin, W; Lin, Z; Qu, C; Tu, M; Yuan, H; Zheng, D | 1 |
24 other study(ies) available for pyrroles and cyclin d1
| Article | Year |
|---|---|
Aryl[a]pyrrolo[3,4-c]carbazoles as selective cyclin D1-CDK4 inhibitors.
Topics: Antineoplastic Agents; Carbazoles; Cell Division; Cell Line, Tumor; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Humans; Proto-Oncogene Proteins; Pyrroles | 2003 |
Synthetic approaches to indolo[6,7-a]pyrrolo[3,4-c]carbazoles: potent cyclin D1/CDK4 inhibitors.
Topics: Acetamides; Acetates; Antineoplastic Agents; Carbazoles; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Enzyme Inhibitors; Humans; Indoles; Maleimides; Oxidants; Photochemistry; Proto-Oncogene Proteins; Pyrroles; Structure-Activity Relationship | 2004 |
Protein kinase C beta enhances growth and expression of cyclin D1 in human breast cancer cells.
Topics: Breast Neoplasms; Cell Division; Cell Line; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Isoenzymes; Luciferases; Mesylates; Mutation; Protein Kinase C; Protein Kinase C beta; Proto-Oncogene Proteins c-fos; Pyrroles; Recombinant Fusion Proteins; Response Elements; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transfection | 2006 |
Combination of atorvastatin with sulindac or naproxen profoundly inhibits colonic adenocarcinomas by suppressing the p65/β-catenin/cyclin D1 signaling pathway in rats.
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Antineoplastic Combined Chemotherapy Protocols; Atorvastatin; Azoxymethane; beta Catenin; Carcinogens; Colonic Neoplasms; Cyclin D1; eIF-2 Kinase; Enzyme-Linked Immunosorbent Assay; Heptanoic Acids; Immunoenzyme Techniques; Interleukin-4; Male; Naproxen; Nitric Oxide Synthase Type II; Pyrroles; Rats; Rats, Inbred F344; Signal Transduction; Sulindac; Tumor Necrosis Factor-alpha | 2011 |
Sunitinib exerts only limited effects on the proliferation and differentiation of anaplastic thyroid cancer cells.
Topics: Angiogenesis Inducing Agents; Antineoplastic Agents; Cell Death; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Humans; Indoles; Iodide Peroxidase; MAP Kinase Signaling System; Oncogene Protein v-akt; Phosphorylation; Pyrroles; Receptors, Thyrotropin; Sunitinib; Symporters; Thyroglobulin; Thyroid Neoplasms | 2012 |
Antiproliferative effect of two novel COX-2 inhibitors on human keratinocytes.
Topics: Cell Line; Cell Proliferation; Cell Survival; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Gene Expression; Humans; Keratinocytes; NF-kappa B; Pyrroles; RNA, Messenger; Sulfones | 2013 |
Anti-angiogenic and anti-metastatic activity of synthetic phosphoethanolamine.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Renal Cell; Caspase 3; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclin D1; Cytoskeleton; Ethanolamines; Gene Expression Regulation, Neoplastic; Human Umbilical Vein Endothelial Cells; Humans; Indoles; Kidney Tubules, Proximal; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mitochondria; Neoplasm Metastasis; Neovascularization, Pathologic; Oxidation-Reduction; Pyrroles; Rats; Sunitinib; Transcription, Genetic; Vascular Endothelial Growth Factor Receptor-1; Wound Healing | 2013 |
Concurrent inhibition of PI3K and mTORC1/mTORC2 overcomes resistance to rapamycin induced apoptosis by down-regulation of Mcl-1 in mantle cell lymphoma.
Topics: Amino Acid Chloromethyl Ketones; Antibiotics, Antineoplastic; Apoptosis; bcl-X Protein; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin D1; Down-Regulation; Drug Resistance, Neoplasm; Humans; Imidazoles; Indoles; Lymphoma, Mantle-Cell; Mechanistic Target of Rapamycin Complex 1; Mechanistic Target of Rapamycin Complex 2; Multiprotein Complexes; Myeloid Cell Leukemia Sequence 1 Protein; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Quinolines; RNA Interference; RNA, Small Interfering; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases | 2013 |
Curcumin potentiates the ability of sunitinib to eliminate the VHL-lacking renal cancer cells 786-O: rapid inhibition of Rb phosphorylation as a preamble to cyclin D1 inhibition.
Topics: Antineoplastic Agents; CDC2 Protein Kinase; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Survival; Curcumin; Cyclin D1; Cyclin-Dependent Kinase 4; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Indoles; Inhibitory Concentration 50; Niacinamide; Phenylurea Compounds; Phosphorylation; Pyrroles; Retinoblastoma Protein; Signal Transduction; Sorafenib; Sunitinib | 2013 |
Antiproliferative and proapoptotic activity of sunitinib on endothelial and anaplastic thyroid cancer cells via inhibition of Akt and ERK1/2 phosphorylation and by down-regulation of cyclin-D1.
Topics: Animals; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Down-Regulation; Endothelial Cells; ErbB Receptors; Humans; Indoles; Male; MAP Kinase Signaling System; Mice; Mice, Nude; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrroles; Skin; Sunitinib; Thyroid Neoplasms; Vascular Endothelial Growth Factor Receptor-2 | 2013 |
Synthesis, DNA-binding abilities and anticancer activities of triazole-pyrrolo[2,1-c][1,4]benzodiazepines hybrid scaffolds.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzodiazepines; Cell Line, Tumor; Cyclin D1; DNA; Down-Regulation; G1 Phase Cell Cycle Checkpoints; Humans; Isomerism; Mice; Pyrroles; Triazoles; Up-Regulation | 2013 |
IGF1 induces cell proliferation in human pituitary tumors - functional blockade of IGF1 receptor as a novel therapeutic approach in non-functioning tumors.
Topics: Adenoma; Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cyclin D3; Female; Humans; Insulin-Like Growth Factor I; Male; Middle Aged; Pituitary Neoplasms; Protein Processing, Post-Translational; Pyrimidines; Pyrroles; Rats | 2014 |
Dissecting histone deacetylase role in pulmonary arterial smooth muscle cell proliferation and migration.
Topics: Animals; Cell Movement; Cell Proliferation; Cells, Cultured; Cyclin D1; Gene Expression Regulation, Enzymologic; Gene Silencing; Histone Deacetylase Inhibitors; Histone Deacetylases; Hydroxamic Acids; Male; Myocytes, Smooth Muscle; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-akt; Pulmonary Artery; Pyrroles; Rats; Rats, Sprague-Dawley | 2014 |
Pan-Bcl-2 inhibitor obatoclax delays cell cycle progression and blocks migration of colorectal cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Cadherins; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; G1 Phase Cell Cycle Checkpoints; Gene Expression; Humans; Indoles; Nitrophenols; Piperazines; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Sulfonamides | 2014 |
Metformin enhances the anti-adipogenic effects of atorvastatin via modulation of STAT3 and TGF-β/Smad3 signaling.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Atorvastatin; Cell Differentiation; Cell Survival; Cyclin D1; Heptanoic Acids; Homeostasis; Hypoglycemic Agents; Kruppel-Like Transcription Factors; Metformin; Mice; Pyrroles; Signal Transduction; Smad3 Protein; Smad7 Protein; STAT3 Transcription Factor; Transforming Growth Factor beta; Tumor Suppressor Protein p53 | 2015 |
Identification of a novel E-box binding pyrrole-imidazole polyamide inhibiting MYC-driven cell proliferation.
Topics: Animals; Apoptosis; Binding Sites; Burkitt Lymphoma; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase 4; DNA-Binding Proteins; E-Box Elements; Eukaryotic Initiation Factor-4G; Humans; Imidazoles; Mice; Mice, SCID; Nylons; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-myc; Pyrroles; Xenograft Model Antitumor Assays | 2015 |
Differences in gene expression and alterations in cell cycle of acute myeloid leukemia cell lines after treatment with JAK inhibitors.
Topics: bcl-X Protein; Cell Cycle; Cell Line, Tumor; Cyclin D1; Down-Regulation; Gene Expression; Humans; Imidazoles; Janus Kinases; Leukemia, Myeloid, Acute; Nitriles; Piperidines; Protein Kinase Inhibitors; Pyrazoles; Pyridazines; Pyrimidines; Pyrroles; Pyrrolidines; Sulfonamides | 2015 |
Fludioxonil induced the cancer growth and metastasis via altering epithelial-mesenchymal transition via an estrogen receptor-dependent pathway in cellular and xenografted breast cancer models.
Topics: Animals; Antigens, CD; Antineoplastic Agents; Breast Neoplasms; Cadherins; Cathepsin D; Cell Movement; Cell Proliferation; Cell Shape; Cyclin D1; Dioxoles; Epithelial-Mesenchymal Transition; Female; Humans; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Pyrroles; Receptors, Estrogen; Signal Transduction; Tumor Burden; Xenograft Model Antitumor Assays | 2017 |
A Study of Angiogenesis Markers in Patients with Renal Cell Carcinoma Undergoing Therapy with Sunitinib.
Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antigens, Neoplasm; Becaplermin; Biomarkers, Tumor; Carbonic Anhydrase IX; Carcinoma, Renal Cell; Cyclin D1; Disease-Free Survival; Female; Humans; Indoles; Kaplan-Meier Estimate; Kidney Neoplasms; Male; Middle Aged; Neovascularization, Pathologic; Proto-Oncogene Proteins c-sis; Pyrroles; Receptors, Platelet-Derived Growth Factor; Receptors, Vascular Endothelial Growth Factor; Sunitinib; Treatment Outcome; Vascular Endothelial Growth Factor A | 2017 |
Obatoclax, a Pan-BCL-2 Inhibitor, Targets Cyclin D1 for Degradation to Induce Antiproliferation in Human Colorectal Carcinoma Cells.
Topics: Carcinoma; Cell Proliferation; Colorectal Neoplasms; Cyclin D1; Down-Regulation; G1 Phase Cell Cycle Checkpoints; HCT116 Cells; HT29 Cells; Humans; Indoles; Proteolysis; Proto-Oncogene Proteins c-bcl-2; Pyrroles | 2016 |
The homologous recombination protein RAD51 is a promising therapeutic target for cervical carcinoma.
Topics: Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; DNA Breaks, Double-Stranded; DNA Damage; DNA Repair; Female; HeLa Cells; Homologous Recombination; Humans; Molecular Targeted Therapy; Morpholines; Pyrroles; Rad51 Recombinase; Uterine Cervical Neoplasms | 2017 |
Obatoclax, a BH3 Mimetic, Enhances Cisplatin-Induced Apoptosis and Decreases the Clonogenicity of Muscle Invasive Bladder Cancer Cells via Mechanisms That Involve the Inhibition of Pro-Survival Molecules as Well as Cell Cycle Regulators.
Topics: bcl-X Protein; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Dose-Response Relationship, Drug; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Indoles; Neoplasm Invasiveness; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Urinary Bladder; Urinary Bladder Neoplasms | 2019 |
Effects of Fludioxonil on the Cell Growth and Apoptosis in T and B Lymphocytes.
Topics: B-Lymphocytes; bcl-2-Associated X Protein; Caspase 3; Cell Cycle; Cell Line; Cell Proliferation; Cell Survival; Cyclin D1; Cyclin E; Dioxoles; Fungicides, Industrial; Gene Expression Regulation; Humans; Jurkat Cells; Membrane Potential, Mitochondrial; Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyrroles; T-Lymphocytes; Time Factors; Tumor Suppressor Protein p53 | 2019 |
Pyruvate Kinase M2 Tetramerization Protects against Hepatic Stellate Cell Activation and Liver Fibrosis.
Topics: Acetylation; Animals; Cyclin D1; Female; Hepatic Stellate Cells; Histones; Humans; Liver Cirrhosis; Male; Mice; Organic Chemicals; Protein Multimerization; Proto-Oncogene Proteins c-myc; Pyridazines; Pyrroles; Pyruvate Kinase | 2020 |