pyrroles has been researched along with colforsin in 101 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (2.97) | 18.7374 |
| 1990's | 42 (41.58) | 18.2507 |
| 2000's | 41 (40.59) | 29.6817 |
| 2010's | 14 (13.86) | 24.3611 |
| 2020's | 1 (0.99) | 2.80 |
| Authors | Studies |
|---|---|
| Kamei, C; Mukai, T; Tasaka, K | 1 |
| Kamata, K; Kasuya, Y; Miyata, N; Otomo, S; Tsuchida, K; Yamaura, H | 1 |
| Aikawa, T; Itabashi, S; Morikawa, M; Sasaki, H; Sekizawa, K; Takishima, T | 1 |
| Broadley, KJ; Urquhart, RA | 1 |
| Alibhai, KN; Huizinga, JD; Richardson, D | 1 |
| Duty, S; Weston, AH | 1 |
| Berry, JL; Boyle, JP; Chapman, ID; Elliott, KR; Foster, RW; Small, RC; Watt, AJ | 1 |
| Greger, R; Kunzelmann, K; Lindeman, S; Lindeman, V; Pavenstädt, H; Späth, M | 1 |
| Deguchi, K; Nishikawa, M; Saitoh, M; Shirakawa, S | 1 |
| Burkhart, CA; Heym, JH; Ives, JL; Lebel, LA; Macor, JE; Newman, ME; Nielsen, JA; Ryan, K; Schulz, DW; Torgersen, LK | 1 |
| Clark, KL; Drew, GM; Hilditch, A | 1 |
| Dale, MM; Obianime, AW | 1 |
| Fukuzaki, H; Shuntoh, H; Tanaka, C; Taniyama, K | 1 |
| Deguchi, K; Kobayashi, K; Nishikawa, M; Omay, SB; Shirakawa, S; Toyoda, H | 1 |
| Absood, A; Maruno, K; Said, SI | 1 |
| Jino, H; Kurahashi, K; Nakata, Y; Shimizu, Y; Shirahase, H; Usui, H | 1 |
| Maggi, CA; Morbidelli, L; Parenti, A; Santicioli, P; Ziche, M | 1 |
| Aston-Jones, G; Shiekhattar, R | 1 |
| Giuliani, S; Maggi, CA; Santicioli, P | 1 |
| Castillo, PE; Nicoll, RA; Weisskopf, MG; Zalutsky, RA | 1 |
| Heath, BM; Terrar, DA | 1 |
| Grimaldi, M; Navarra, P; Pozzoli, G; Preziosi, P; Schettini, G | 1 |
| Jackson, WF | 1 |
| Carl, A; Du, C; Keef, KD; Sanders, KM; Smith, TK | 1 |
| McGrath, JC; Smith, GC | 1 |
| Alouan, LA; Armour, CL; Black, JL; Johnson, PR; Marthan, R; McKay, KO; Savineau, JP; Tunon de Lara, JM; Villanove, X | 1 |
| Ko, FN; Lin, CH; Lu, ST; Teng, CM; Wu, YC | 1 |
| Bamba, N; Hishinuma, A; Kasai, K; Shimoda, SI; So, S; Yamanaka, T | 1 |
| Catravas, JD; Del Monte, MA; Marczin, N; Miyamoto, Y | 1 |
| Komalavilas, P; Lincoln, TM | 1 |
| Navaratnam, DS; Oberholtzer, JC; Scott, SP; Su, HS | 1 |
| Gidday, JM; Maceren, RG; Meier, JA; Shah, AR; Zhu, Y | 1 |
| Babenko, A; Vassort, G | 1 |
| Huang, Y; Kwok, KH | 1 |
| Barberá, M; Cortijo, J; Higueras, J; Maruenda, A; Morcillo, EJ; Ortiz, JL; Sarría, B | 1 |
| Cikós, T; Kalthoff, H; Krull, NB; Ungefroren, H | 1 |
| Akagi, M; Akagi, R; Fukuishi, N; Matsuura, S; Nakagawa, C; Sakaguchi, M | 1 |
| Allen, LF; Fatima, S; Kan, H; Malik, KU; Parmentier, JH; Ruan, Y | 1 |
| Fillion, G; Guezennec, Y; Liscia, P; Seguin, L | 1 |
| Endo, K; Nakamura, M; Nakata, K | 1 |
| Bobirnac, I; Bruinvels, AT; Danzeisen, M; Gazi, L; Geisse, S; Hoyer, D; Schoeffter, P; Schüpbach, E; Sommer, B; Tricklebank, M | 1 |
| Polte, T; Schröder, H | 1 |
| Ardenghi, P; Bevilaqua, L; Bianchin, M; Bromberg, E; Izquierdo, I; Medina, JH; Quevedo, J; Schaeffer, E; Schmitz, PK; Schröder, N; Walz, R | 1 |
| Branchek, TA; Zgombick, JM | 1 |
| Bryce, PJ; Dascombe, MJ; Hutchinson, IV | 1 |
| Bailly, JM; Deschamps, F; Fillion, G; Grimaldi, B; Kochanek, M; Lambrozo, J; Massot, O | 1 |
| Dick, JM; Lefebvre, RA | 1 |
| Coyne, MD; Gwathmey, JK; Kim, CS | 1 |
| Derweesh, IH; Weiss, RM; Wheeler, MA | 1 |
| Huang, YY; Kandel, ER; Martin, KC | 1 |
| Kamei, C; Kirino, Y; Mio, M | 1 |
| Hsu, WH; Prapong, T; Uemura, E | 1 |
| Akagawa, K; Kohara, K; Ogura, A; Yamaguchi, K | 1 |
| Karle, CA; Kathöfer, S; Kiehn, J; Schoels, W; Zhang, W; Zitron, E | 1 |
| Cho, KW; Cui, X; Jin, JY; Kim, SH; Kim, SZ; Lee, HS; Wen, JF; Xu, WX | 1 |
| Bełtowski, J; Górny, D; Marciniak, A; Wójcicka, G | 1 |
| Aravamudan, B; Broadie, K | 1 |
| Carlson, RR; Dudman, JT; Konradi, C; Macías, W | 1 |
| Facci, L; Franceschini, D; Pangallo, M; Skaper, SD; Stevens, DA; Strijbos, PJ | 1 |
| Binz, T; Brose, N; Matti, U; Nagy, G; Neher, E; Reim, K; Rettig, J; Sørensen, JB | 1 |
| Puggina, E; Sellitti, D | 1 |
| Dominguez, G; Kuhar, MJ | 1 |
| Fresno, M; Iñiguez, MA; Jimenez, JL; Muñoz-Fernández, MA | 1 |
| Binder, BR; Kaun, C; Okajima, K; Uchiba, M; Wojta, J | 1 |
| Ishisaki, A; Kanno, Y; Kozawa, O; Nakajima, K; Numata, O; Tokuda, H; Yoshida, M | 1 |
| Feng, L; Ji, Y; Lu, B; Pang, PT | 1 |
| Barnes, NY; Parent, AT; Sisodia, SS; Taniguchi, Y; Thinakaran, G | 1 |
| Chang, YC; Chen, IM; Chen, YH; Lin, CH; Lin, PJ; Lin, PL; Lu, KL; Tsai, MC | 1 |
| Cox, CL; Govindaiah, G | 1 |
| Baines, DL; Woollhead, AM | 1 |
| Kennedy, TE; Moore, SW | 1 |
| Abel, T; Isiegas, C; Nguyen, PV; Young, JZ | 1 |
| Kang, SK; Kim, CH; Kim, YH; Park, YG | 1 |
| Miller, GM; Xie, Z | 1 |
| Hirakawa, M; Ito, Y; Karashima, Y; Kimura, C; Oike, M; Watanabe, M | 1 |
| Eggo, MC; Susarla, R; Watkinson, JC | 1 |
| Fleischmann, BK; Hescheler, J; Reppel, M; Reuter, H; Sasse, P; Schunkert, H | 1 |
| Caruso-Neves, C; Einicker-Lamas, M; Masuda, CA; Nascimento, MT; Oliveira, MM | 1 |
| Bakiri, Y; Lafourcade, M; Manzoni, OJ; Mato, S; Robbe, D | 1 |
| Adwanikar, H; Fu, Y; Han, J; Ishola, T; Neugebauer, V; Ramsey, C; Scerbo, M | 1 |
| Tanaka, M; Watanabe, Y; Yoshimoto, K | 1 |
| Afif, H; Benderdour, M; Chabane, N; Duval, N; Fahmi, H; Martel-Pelletier, J; Mfuna-Endam, L; Motiani, RK; Pelletier, JP; Trebak, M; Zayed, N | 1 |
| Bhattacharjee, A; Nuwer, MO; Picchione, KE | 1 |
| Abbruzzese, A; Caraglia, M; Chiosi, E; Di Gesto, D; Illiano, F; Illiano, G; Marra, M; Naviglio, S; Romano, M; Sorrentino, A; Sorvillo, L; Spina, A | 1 |
| Chung, KC; Kim, SS; Seo, SR | 1 |
| Chioni, AM; Djamgoz, MB; Grose, R; Shao, D | 1 |
| Ikeda, T; Ishii, H; Kojima, Y; Masuda, Y; Sugimoto, K; Takada, K | 1 |
| Carter, BD; Limpert, AS | 1 |
| Chiosi, E; Di Gesto, D; Giordano, A; Illiano, F; Illiano, G; Naviglio, S; Spina, A | 1 |
| Ikeda, H; Kiritoshi, T; Murase, K | 1 |
| Berson, DM; Van Hook, MJ; Wong, KY | 1 |
| Dai, Y; Kobayashi, K; Kogure, Y; Noguchi, K; Wan, Y; Wang, S; Yamanaka, H; Zhang, W; Zhu, W | 1 |
| Harraz, OF; Welsh, DG | 1 |
| Berrout, J; Boukelmoune, N; Mamenko, M; O'Neil, RG; Pochynyuk, O; Zaika, OL | 1 |
| Bougnoux, P; Chantôme, A; Chevalier, S; Clarysse, L; Guéguinou, M; Potier-Cartereau, M; Vandecasteele, G; Vandier, C | 1 |
| Almami, I; Bonner, PL; Dickenson, JM; Hargreaves, AJ | 1 |
| Hsieh, PC; Hung, SC; Lin, SP; Wang, YL | 1 |
| Amano, T; Hara, T; Ide, S; Kaneda, K; Kaneko, T; Minami, M; Ohno, A; Takahashi, D; Yoshioka, M | 1 |
| Gerst, F; Häring, HU; Lutz, SZ; Ullrich, A; Ullrich, S | 1 |
| Baran, CN; Clason, TA; Girard, BM; Hardwick, JC; May, V; Merriam, LA; Parsons, RL; Tompkins, JD | 1 |
| Abe, M; Akiya, Y; Baba, S; Fukuda, N; Kobayashi, H; Matsumoto, T; Tsunemi, A | 1 |
101 other study(ies) available for pyrroles and colforsin
| Article | Year |
|---|---|
Histamine-induced depolarization and the cyclic AMP--protein kinase A system in isolated guinea pig adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Alprostadil; Animals; Carbazoles; Colforsin; Cyclic AMP; Electrophysiology; Epididymis; Guinea Pigs; Histamine; In Vitro Techniques; Indoles; Insulin; Isoproterenol; Male; Membrane Potentials; Protein Kinase C; Protein Kinases; Pyrroles; Rats; Rats, Wistar | 1992 |
Changes in responsiveness of the aorta to vasorelaxant agents in genetically diabetic rats: a study in WBN/Kob rats.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Colforsin; Cromakalim; Diabetes Mellitus, Experimental; Endothelium, Vascular; Isoproterenol; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Pyrroles; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Vasodilator Agents | 1992 |
The role of cyclic AMP in non-adrenergic non-cholinergic contraction in guinea-pig bronchi.
Topics: Animals; Autonomic Nervous System; Benzopyrans; Bronchi; Bronchodilator Agents; Bucladesine; Colforsin; Cromakalim; Cyclic AMP; Electric Stimulation; Ethanolamines; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurons, Afferent; Nitroprusside; Procaterol; Pyrroles; Substance P; Theophylline | 1992 |
The indirect negative inotropic effects of the P1-receptor agonist, L-phenylisopropyladenosine, in guinea-pig isolated cardiac preparations: comparison with cromakalim.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atrial Function; Atrial Function, Left; Benzopyrans; Cardiotonic Agents; Colforsin; Cromakalim; Depression, Chemical; Guinea Pigs; Heart Atria; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Phenylisopropyladenosine; Pyrroles; Stimulation, Chemical; Time Factors | 1992 |
On the pharmacological and physiological role of glibenclamide-sensitive potassium channels in colonic smooth muscle.
Topics: Animals; Benzopyrans; Carbachol; Colforsin; Colon; Cromakalim; Dogs; Drug Interactions; Electric Stimulation; Female; Gallopamil; Glyburide; Male; Muscle Contraction; Muscle, Smooth; Potassium Channels; Pyrroles; Stereoisomerism | 1992 |
Characteristics of the contractile response of rabbit aorta produced by cromakalim in calcium-free solution.
Topics: Animals; Aorta; Benzopyrans; Calcium; Colforsin; Cromakalim; Guanidines; Male; Microelectrodes; Minoxidil; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitroglycerin; Pinacidil; Potassium; Potassium Channels; Pyridines; Pyrroles; Rabbits; Vasoconstriction | 1992 |
Biochemical and electrical aspects of the tracheal relaxant action of AH 21-132.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Action Potentials; Airway Resistance; Animals; Benzopyrans; Biomechanical Phenomena; Cell Membrane; Colforsin; Cromakalim; Female; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Naphthyridines; Nucleotides, Cyclic; Papaverine; Pyrroles; Sodium Nitrite; Stereoisomerism; Trachea | 1991 |
Effect of depolarizing and hyperpolarizing agents on the membrane potential difference of primary cultures of rabbit aorta vascular smooth muscle cells.
Topics: Animals; Aorta; Benzopyrans; Cattle; Cells, Cultured; Colforsin; Cromakalim; Glyburide; Membrane Potentials; Muscle, Smooth, Vascular; Nucleotides; Pyrroles; Rabbits | 1991 |
[Intracellular actions of antiplatelet drugs which affect cyclic AMP metabolism in platelets--their effects on Ca2+ mobilization and protein phosphorylation in human platelets].
Topics: Alprostadil; Blood Platelets; Calcium; Carbazoles; Colforsin; Cyclic AMP; Humans; Indoles; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Kinase C; Pyrroles; Thromboxane A2 | 1990 |
3-(1,2,5,6-Tetrahydropyrid-4-yl)pyrrolo[3,2-b]pyrid-5-one: a potent and selective serotonin (5-HT1B) agonist and rotationally restricted phenolic analogue of 5-methoxy-3-(1,2,5,6-tetrahydropyrid-4-yl)indole.
Topics: Adenylyl Cyclase Inhibitors; Animals; Chemical Phenomena; Chemistry; Colforsin; Cyclization; Eating; Guinea Pigs; Hippocampus; Indoles; Molecular Structure; Paraventricular Hypothalamic Nucleus; Pyridines; Pyrroles; Rats; Receptors, Serotonin; Serotonin; Substantia Nigra | 1990 |
Potentiation of the effects of dopamine in the rabbit isolated splenic artery by 3-isobutyl-1-methylxanthine or forskolin.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Benzopyrans; Colforsin; Cromakalim; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Male; Parasympatholytics; Purinergic Antagonists; Purinones; Pyrroles; Rabbits; Splenic Artery; Theophylline | 1989 |
The effect of relaxants working through different transduction mechanisms on the tonic contraction produced in rat aorta by 4 beta-phorbol dibutyrate.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Colforsin; Cromakalim; In Vitro Techniques; Isoproterenol; Male; Methoxamine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Parasympatholytics; Phorbol 12,13-Dibutyrate; Pyrroles; Rats; Rats, Inbred Strains; Xanthines | 1989 |
Inhibition by cyclic AMP of phorbol ester-potentiated norepinephrine release from guinea pig brain cortical synaptosomes.
Topics: Alkaloids; Animals; Bucladesine; Carbazoles; Cerebral Cortex; Colforsin; Cyclic AMP; Enzyme Activation; Female; Guinea Pigs; Indoles; Male; Norepinephrine; Polymyxin B; Potassium; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Pyrroles; Staurosporine; Synaptosomes; Tetradecanoylphorbol Acetate | 1988 |
Forskolin potentiates G-CSF-induced proliferation of a murine myeloblastic leukemia cell line.
Topics: Animals; Carbazoles; Cell Division; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Drug Synergism; Enzyme Activation; Granulocyte Colony-Stimulating Factor; Indoles; Interleukin-3; Leukemia, Experimental; Leukemia, Myeloid, Acute; Mice; Mice, Inbred DBA; Pyrroles; Signal Transduction; Tumor Cells, Cultured | 1994 |
VIP inhibits basal and histamine-stimulated proliferation of human airway smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Carbazoles; Cell Cycle; Cell Division; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA; Dose-Response Relationship, Drug; Glucagon; Histamine; Histamine Antagonists; Humans; Indoles; Kinetics; Muscle, Smooth; Pyrroles; Thymidine; Trachea; Vasoactive Intestinal Peptide | 1995 |
Pharmacological natures of caffeine-induced endothelium-dependent and -independent contraction in canine mesenteric artery.
Topics: Adenylyl Cyclases; Animals; Benzopyrans; Caffeine; Calcium; Calcium Channel Blockers; Colforsin; Cromakalim; Dogs; Edetic Acid; Egtazic Acid; Endothelium, Vascular; Female; In Vitro Techniques; Magnesium; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitroglycerin; Potassium Channels; Pyrroles; Vasodilator Agents | 1995 |
Calcitonin gene-related peptide selectively increases cAMP levels in the guinea-pig ureter.
Topics: Animals; Benzopyrans; Calcitonin Gene-Related Peptide; Colforsin; Cromakalim; Cyclic AMP; Cyclic GMP; Drug Interactions; Glyburide; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Potassium Channels; Pyrroles; Ureter | 1995 |
Activation of adenylate cyclase attenuates the hyperpolarization following single action potentials in brain noradrenergic neurons independently of protein kinase A.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Adenylyl Cyclases; Alkaloids; Animals; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; In Vitro Techniques; Indoles; Isoquinolines; Locus Coeruleus; Neurons; Norepinephrine; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Sprague-Dawley; Staurosporine; Thionucleotides | 1994 |
Multiple mechanisms in the smooth muscle relaxant action of calcitonin gene-related peptide (CGRP) in the guinea-pig ureter.
Topics: Action Potentials; Animals; Arginine; Benzopyrans; Calcitonin Gene-Related Peptide; Colforsin; Cromakalim; Dose-Response Relationship, Drug; Electric Stimulation; Glyburide; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Nitroarginine; Parasympatholytics; Pyrroles; Ureter | 1994 |
Mediation of hippocampal mossy fiber long-term potentiation by cyclic AMP.
Topics: Animals; Calcium; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Indoles; Isoquinolines; Long-Term Potentiation; Models, Biological; Nerve Fibers; Presynaptic Terminals; Pyramidal Cells; Pyrroles; Sulfonamides; Synaptic Transmission | 1994 |
Effect of glibenclamide, forskolin, and isoprenaline on the parallel activation of KATP and reduction of IK by cromakalim in cardiac myocytes.
Topics: Animals; Benzopyrans; Cells, Cultured; Colforsin; Cromakalim; Glyburide; Guinea Pigs; Isoproterenol; Myocardium; Potassium Channels; Pyrroles; Sodium-Potassium-Exchanging ATPase; Vasodilator Agents | 1994 |
Vasoactive intestinal peptide and forskolin stimulate interleukin 6 production by rat cortical astrocytes in culture via a cyclic AMP-dependent, prostaglandin-independent mechanism.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Astrocytes; Bucladesine; Carbazoles; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprost; Dinoprostone; Indoles; Interleukin-6; Prostaglandins; Pyrroles; Radioimmunoassay; Rats; Rats, Wistar; Vasoactive Intestinal Peptide | 1994 |
Arteriolar tone is determined by activity of ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Animals; Arterioles; Benzopyrans; Bucladesine; Colforsin; Cricetinae; Cromakalim; Epoprostenol; Glyburide; Guanidines; Isoproterenol; Male; Mesocricetus; Methacholine Chloride; Muscle Tonus; Muscle, Smooth, Vascular; Muscles; Nitroprusside; Pinacidil; Potassium Channels; Pyrroles; Quaternary Ammonium Compounds; Vasoconstriction; Vasodilation; Vasodilator Agents | 1993 |
Mechanism of cyclic AMP-induced hyperpolarization in canine colon.
Topics: Animals; Benzopyrans; Calcium; Colforsin; Colon; Cromakalim; Cyclic AMP; Dogs; Female; In Vitro Techniques; Male; Membrane Potentials; Potassium Channels; Pyrroles | 1994 |
Characterisation of the effect of oxygen tension on response of fetal rabbit ductus arteriosus to vasodilators.
Topics: Adenosine; Animals; Atrial Natriuretic Factor; Benzopyrans; Colforsin; Cromakalim; Culture Techniques; Cyclooxygenase Inhibitors; Dinoprostone; Ductus Arteriosus; Epoprostenol; Flurbiprofen; Indomethacin; Nifedipine; Nitroprusside; Norepinephrine; Oxygen; Pyrroles; Rabbits; Vasodilator Agents | 1993 |
Sensitization decreases relaxation in human isolated airways.
Topics: Asthma; Benzopyrans; Bronchi; Bucladesine; Carbachol; Colforsin; Cromakalim; Dose-Response Relationship, Drug; Humans; Immunization, Passive; Immunoglobulin E; In Vitro Techniques; Isoproterenol; Muscle Relaxation; Muscle Tonus; Parasympatholytics; Pyrroles; Verapamil | 1993 |
The relaxant actions on guinea-pig trachealis of atherosperminine isolated from Fissistigma glaucescens.
Topics: Alkaloids; Animals; Benzopyrans; Calcium; Calmodulin; Colforsin; Cromakalim; Cyclic AMP; Cyclic GMP; Egtazic Acid; Epithelium; Female; Glyburide; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nifedipine; Nitroprusside; Phenanthrenes; Plants, Medicinal; Propranolol; Pyrroles; Theophylline; Trachea; Vasodilator Agents | 1993 |
Growth regulation of the human papillary thyroid cancer cell line by protein tyrosine kinase and cAMP-dependent protein kinase.
Topics: Adult; Bucladesine; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cystadenoma, Papillary; Enzyme Inhibitors; Female; Growth Substances; Humans; Indoles; Protein-Tyrosine Kinases; Pyrroles; Thyroid Neoplasms; Thyrotropin; Tumor Cells, Cultured | 1994 |
Cholera toxin enhances taurine uptake in cultures of human retinal pigment epithelial cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Carbazoles; Carrier Proteins; Cell Line; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Indoles; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Phosphodiesterase Inhibitors; Pigment Epithelium of Eye; Pyrroles; Taurine | 1996 |
Phosphorylation of the inositol 1,4,5-trisphosphate receptor. Cyclic GMP-dependent protein kinase mediates cAMP and cGMP dependent phosphorylation in the intact rat aorta.
Topics: Alkaloids; Angiotensin II; Animals; Aorta; Calcium Channels; Carbazoles; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Indoles; Inositol 1,4,5-Trisphosphate Receptors; Male; Nitroprusside; Phosphorylation; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Thionucleotides; Time Factors | 1996 |
Proliferation in the auditory receptor epithelium mediated by a cyclic AMP-dependent signaling pathway.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Carbazoles; Chickens; Cochlea; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA Replication; Enzyme Activation; Enzyme Inhibitors; Gentamicins; Hair Cells, Auditory; Hearing Loss, Sensorineural; Indoles; Isoquinolines; Organ Culture Techniques; Pyrroles; Regeneration; Signal Transduction; Sulfonamides | 1996 |
KATP channels mediate adenosine-induced hyperemia in retina.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Benzopyrans; Colforsin; Cromakalim; Cyclic AMP; Dose-Response Relationship, Drug; Fluorescein Angiography; Glyburide; Hyperemia; Muscle, Smooth, Vascular; Potassium Channel Blockers; Potassium Channels; Pyrroles; Regional Blood Flow; Retinal Vessels; Second Messenger Systems; Signal Transduction; Swine; Vasodilation; Vasodilator Agents | 1996 |
Enhancement of the ATP-sensitive K+ current by extracellular ATP in rat ventricular myocytes. Involvement of adenylyl cyclase-induced subsarcolemmal ATP depletion.
Topics: Adenine; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Animals; Benzopyrans; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Colforsin; Cromakalim; Deoxyadenine Nucleotides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Space; GTP-Binding Proteins; Guanidines; Guanosine Triphosphate; Heart Ventricles; Male; Patch-Clamp Techniques; Peptide Fragments; Pinacidil; Potassium Channels; Pyrroles; Rats; Rats, Wistar; Uncoupling Agents | 1997 |
Effects of putative K+ channel blockers on beta-adrenoceptor-mediated vasorelaxation of rat mesenteric artery.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Barium; Benzopyrans; Calcium; Charybdotoxin; Colforsin; Cromakalim; Cyclic AMP; Dose-Response Relationship, Drug; Fenoterol; Glyburide; Isoproterenol; Male; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Potassium Channel Blockers; Pyrroles; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents; Vasodilator Agents | 1997 |
Halothane inhibits endothelium-dependent relaxation elicited by acetylcholine in human isolated pulmonary arteries.
Topics: Acetylcholine; Adenylyl Cyclases; Anesthetics, Inhalation; Benzopyrans; Colforsin; Cromakalim; Drug Evaluation, Preclinical; Endothelium, Vascular; Enzyme Activation; Guanylate Cyclase; Halothane; Humans; Immunoglobulin E; In Vitro Techniques; Nitroprusside; Pulmonary Artery; Pyrroles; Vasodilator Agents | 1997 |
Biglycan gene promoter activity in osteosarcoma cells is regulated by cyclic AMP.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Biglycan; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Extracellular Matrix Proteins; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Indoles; Osteosarcoma; Plasmids; Promoter Regions, Genetic; Proteoglycans; Pyrroles; RNA, Messenger; Sequence Deletion; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1997 |
The mechanisms of compound 48/80-induced superoxide generation mediated by A-kinase in rat peritoneal mast cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blotting, Western; Bucladesine; Carbazoles; Colforsin; Cyclic AMP-Dependent Protein Kinases; Granulomatous Disease, Chronic; Immunohistochemistry; Indoles; Isoproterenol; Male; Mast Cells; NADPH Oxidases; p-Methoxy-N-methylphenethylamine; Phosphoproteins; Protein Kinase C; Pyrroles; Rats; Rats, Wistar; Recombinant Proteins; Superoxides; Terpenes | 1997 |
Alpha-1A adrenergic receptor stimulation with phenylephrine promotes arachidonic acid release by activation of phospholipase D in rat-1 fibroblasts: inhibition by protein kinase A.
Topics: Adenine; Adenylate Cyclase Toxin; Animals; Arachidonic Acid; Calcimycin; Carbazoles; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Glycerides; GTP-Binding Proteins; Indoles; Lipase; Phenylephrine; Phospholipase D; Phospholipases A; Phospholipases A2; Prazosin; Pyrroles; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-1; Transfection; Virulence Factors, Bordetella | 1998 |
Effects of moderate and intensive training on functional activity of central 5-HT1B receptors in the rat substantia nigra.
Topics: Adenylyl Cyclases; Animals; Colforsin; Enzyme Induction; Male; Physical Conditioning, Animal; Pyridines; Pyrroles; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Restraint, Physical; Serotonin Receptor Agonists; Substantia Nigra | 1998 |
Mucin-like glycoprotein secretion is mediated by cyclic-AMP and protein kinase C signal transduction pathways in rat corneal epithelium.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbazoles; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelium, Corneal; Indoles; Male; Mucins; Naphthalenes; Protein Kinase C; Pyrroles; Rats; Rats, Sprague-Dawley; Signal Transduction | 1998 |
The agonist activities of the putative antipsychotic agents, L-745,870 and U-101958 in HEK293 cells expressing the human dopamine D4.4 receptor.
Topics: Aminopyridines; Antipsychotic Agents; Cell Line; Clozapine; Colforsin; Cyclic AMP; Dopamine; Dopamine Agonists; Dopamine Antagonists; Humans; Kidney; Piperidines; Pyridines; Pyrroles; Raclopride; Receptors, Dopamine D2; Receptors, Dopamine D4; Recombinant Proteins; Salicylamides; Spiperone | 1998 |
Cyclic AMP mediates endothelial protection by nitric oxide.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Alkaloids; Animals; Carbazoles; Cattle; Cell Line; Cell Survival; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic N-Oxides; Dideoxyadenosine; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Imidazoles; Indoles; Kinetics; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Penicillamine; Pulmonary Artery; Pyrroles; Quinoxalines; S-Nitroso-N-Acetylpenicillamine; Tumor Necrosis Factor-alpha | 1998 |
Drugs acting upon the cyclic adenosine monophosphate/protein kinase A signalling pathway modulate memory consolidation when given late after training into rat hippocampus but not amygdala.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Amygdala; Animals; Avoidance Learning; Benzazepines; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine Agonists; Dopamine Antagonists; Hippocampus; Indoles; Male; Memory; Norepinephrine; Piperazines; Pyrroles; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Dopamine D1; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction; Time Factors; Timolol | 1997 |
Native 5-HT1B receptors expressed in OK cells display dual coupling to elevation of intracellular calcium concentrations and inhibition of adenylate cyclase.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Calcium; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Kidney; Methiothepin; Opossums; Oxadiazoles; Pertussis Toxin; Pindolol; Piperazines; Pyridines; Pyrroles; Radioligand Assay; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Virulence Factors, Bordetella | 1998 |
Immunomodulatory effects of pharmacological elevation of cyclic AMP in T lymphocytes proceed via a protein kinase A independent mechanism.
Topics: Adjuvants, Immunologic; Carbazoles; Colforsin; Cyclic AMP; Enzyme Inhibitors; Humans; Indoles; Interferon-gamma; Interleukin-2; Isoquinolines; Lymphocyte Activation; Protein Kinase C; Pyrroles; Sulfonamides; T-Lymphocytes; Thionucleotides | 1999 |
Magnetic field desensitizes 5-HT(1B) receptor in brain: pharmacological and functional studies.
Topics: Animals; Binding, Competitive; Cell Membrane; Cerebral Cortex; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electromagnetic Fields; Guanosine Triphosphate; Guinea Pigs; Humans; In Vitro Techniques; Ligands; Protein Conformation; Pyridines; Pyrroles; Rats; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Synaptosomes; Temperature; Transfection | 2000 |
Interplay between nitric oxide and vasoactive intestinal polypeptide in the pig gastric fundus smooth muscle.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Amidines; Animals; Arginine; Benzylamines; Carbazoles; Colforsin; Cyclic AMP; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gastric Fundus; In Vitro Techniques; Indoles; Isoquinolines; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; Oxadiazoles; Protein Kinase Inhibitors; Pyrroles; Quinoxalines; Sulfonamides; Swine; Thionucleotides; Vasoactive Intestinal Peptide | 2000 |
Voltage-dependent calcium channels in ventricular cells of rainbow trout: effect of temperature changes in vitro.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Adaptation, Physiological; Animals; Barium; Body Temperature; Cadmium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cardiotonic Agents; Cold Temperature; Colforsin; Heart Ventricles; In Vitro Techniques; Ion Channel Gating; Isoproterenol; Membrane Potentials; Muscle Fibers, Skeletal; Myocardial Contraction; Myocardium; Nifedipine; Oncorhynchus mykiss; Patch-Clamp Techniques; Pyrroles; Tetrodotoxin | 2000 |
Alterations in G-proteins and beta-adrenergic responsive adenylyl cyclase in rat urinary bladder during aging.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Blotting, Western; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; GTP-Binding Proteins; Indoles; Isoproterenol; Muscle, Smooth; Pertussis Toxin; Pyrroles; Rats; Receptors, Adrenergic, beta; Urinary Bladder; Virulence Factors, Bordetella | 2000 |
Both protein kinase A and mitogen-activated protein kinase are required in the amygdala for the macromolecular synthesis-dependent late phase of long-term potentiation.
Topics: Amygdala; Animals; Auditory Cortex; Carbazoles; Cerebral Cortex; Colforsin; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; In Vitro Techniques; Indoles; Isoproterenol; Long-Term Potentiation; Mitogen-Activated Protein Kinases; Phosphorylation; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Signal Transduction; Thalamus; Transcription, Genetic | 2000 |
Desensitization of beta2-adrenoceptor and hypersensitization to phosphodiesterase inhibitors elicited by beta2-agonists in guinea pig eosinophils.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Bucladesine; Calcimycin; Carbazoles; Cells, Cultured; Clenbuterol; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Eosinophil Peroxidase; Eosinophils; Fenoterol; Guinea Pigs; Indoles; Intracellular Fluid; Ionophores; Male; Peroxidases; Phosphodiesterase Inhibitors; Pyrroles; Receptors, Adrenergic, beta-2; Theophylline; Time Factors | 2000 |
G protein and cAMP-dependent protein kinase mediate amyloid beta-peptide inhibition of neuronal glucose uptake.
Topics: Adenylyl Cyclases; Amyloid beta-Peptides; Animals; Bucladesine; Carbazoles; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucose; GTP-Binding Proteins; Hippocampus; Indoles; Neurons; Peptide Fragments; Pyrroles; Rats; Rats, Sprague-Dawley | 2001 |
Increase in number of functional release sites by cyclic AMP-dependent protein kinase in cultured neurons isolated from hippocampal dentate gyrus.
Topics: Animals; Animals, Newborn; Calcium; Carbazoles; Cells, Cultured; Colforsin; Cyclic AMP; Dentate Gyrus; Enzyme Inhibitors; Exocytosis; Extracellular Space; Indoles; Long-Term Potentiation; Neurotransmitter Agents; Potassium Chloride; Presynaptic Terminals; Protein Kinases; Pyrroles; Rats; Signal Transduction; Strontium; Synaptic Transmission; Thionucleotides | 2001 |
Rapid component I(Kr) of the guinea-pig cardiac delayed rectifier K(+) current is inhibited by beta(1)-adrenoreceptor activation, via cAMP/protein kinase A-dependent pathways.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Depression, Chemical; Enzyme Inhibitors; Guinea Pigs; Imidazoles; Indoles; Isoproterenol; Myocardium; Patch-Clamp Techniques; Potassium Channels, Inwardly Rectifying; Pyrroles; Xamoterol | 2002 |
Protein kinase-dependent and Ca(2+)-independent cAMP inhibition of ANP release in beating rabbit atria.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Atrial Function; Atrial Natriuretic Factor; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Indoles; Myocardial Contraction; Myocardium; Nifedipine; Phosphodiesterase Inhibitors; Protein Kinase Inhibitors; Protein Kinases; Pyrroles; Rabbits; Staurosporine | 2002 |
The opposite effects of cyclic AMP-protein kinase a signal transduction pathway on renal cortical and medullary Na+,K+-ATPase activity.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Alkaloids; Animals; Arachidonic Acid; Bucladesine; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytochrome P-450 Enzyme System; Enzyme Activation; Enzyme Inhibitors; Hydroxyeicosatetraenoic Acids; Indoles; Kidney Cortex; Kidney Medulla; Male; Okadaic Acid; Phosphodiesterase Inhibitors; Pyrroles; Rats; Rats, Wistar; Signal Transduction; Sodium-Potassium-Exchanging ATPase | 2002 |
Synaptic Drosophila UNC-13 is regulated by antagonistic G-protein pathways via a proteasome-dependent degradation mechanism.
Topics: Acetylcysteine; Animals; Antibodies; Blotting, Western; Caenorhabditis elegans Proteins; Carbazoles; Carrier Proteins; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cysteine Endopeptidases; Drosophila; Drosophila Proteins; Drug Interactions; Enzyme Inhibitors; Estrenes; GTP-Binding Proteins; Helminth Proteins; Horseradish Peroxidase; Immunohistochemistry; Indoles; Insect Proteins; Maleimides; Microscopy, Confocal; Multienzyme Complexes; Mutation; Neomycin; Neuromuscular Junction; Oligopeptides; Phorbol Esters; Phospholipid Ethers; Presynaptic Terminals; Proteasome Endopeptidase Complex; Pyrroles; Pyrrolidinones; Synapses; Tumor Suppressor Proteins; Type C Phospholipases | 2003 |
Striatal proenkephalin gene induction: coordinated regulation by cyclic AMP and calcium pathways.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antihypertensive Agents; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Carcinogens; Cells, Cultured; Colforsin; Corpus Striatum; Cyclic AMP; Drug Interactions; Embryo, Mammalian; Enkephalins; Enzyme Inhibitors; Gene Expression Regulation, Developmental; Humans; Isoquinolines; Neurons; Nifedipine; Protein Precursors; Pyrroles; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetradecanoylphorbol Acetate; Transcriptional Activation; Transfection | 2003 |
Corticotropin-releasing factor (CRF) and related peptides confer neuroprotection via type 1 CRF receptors.
Topics: 1-Methyl-3-isobutylxanthine; Amphibian Proteins; Amyloid beta-Peptides; Animals; Animals, Newborn; Apoptosis; Blotting, Western; Cell Survival; Cells, Cultured; Cerebellum; Cerebral Cortex; Chromatin; Chromones; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Glycogen Synthase Kinase 3; Hippocampus; In Situ Nick-End Labeling; Inhibitory Concentration 50; L-Lactate Dehydrogenase; Mitogen-Activated Protein Kinase Kinases; Morpholines; Neurons; Neuroprotective Agents; Peptide Fragments; Peptide Hormones; Peptides; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Thionucleotides; Time Factors; Urocortins; Urotensins; Vasodilator Agents | 2003 |
Regulation of releasable vesicle pool sizes by protein kinase A-dependent phosphorylation of SNAP-25.
Topics: Alanine; Animals; Blotting, Western; Calcineurin; Calcium; Carbazoles; Carrier Proteins; Catecholamines; Cattle; Cells, Cultured; Chromaffin Cells; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Exocytosis; Humans; Indoles; Intracellular Signaling Peptides and Proteins; Kidney; Membrane Potentials; Membrane Proteins; Models, Biological; Mutation; Nerve Tissue Proteins; Patch-Clamp Techniques; Peptide Fragments; Phosphorylation; Photolysis; Pyrethrins; Pyrroles; Secretory Vesicles; Synaptosomal-Associated Protein 25; Threonine; Time Factors; Transfection | 2004 |
Cyclic adenosine monophosphate (cAMP) increases natriuretic peptide receptor C (NPR-C) expression in human aortic smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; Aorta; Atrial Natriuretic Factor; Bucladesine; Carbazoles; Cell Culture Techniques; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Guanylate Cyclase; Humans; Indoles; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Protein Binding; Pyrroles; Receptors, Atrial Natriuretic Factor; RNA, Messenger; Signal Transduction | 2004 |
Transcriptional regulation of the CART promoter in CATH.a cells.
Topics: Animals; Cell Line; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation; Locus Coeruleus; Mice; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Neurotransmitter Agents; Promoter Regions, Genetic; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; RNA, Messenger; Transcription, Genetic | 2004 |
Effect of phosphodiesterase 4 inhibitors on NFAT-dependent cyclooxygenase-2 expression in human T lymphocytes.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Carbazoles; Colforsin; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclooxygenase 2; DNA; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Immunoblotting; Indoles; Isoquinolines; Jurkat Cells; Luciferases; Membrane Proteins; NFATC Transcription Factors; Nuclear Proteins; Plasmids; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Protein Binding; Pyrroles; RNA, Messenger; Rolipram; Sulfonamides; T-Lymphocytes; Transcription Factors; Transcriptional Activation; Transfection | 2004 |
Inhibition of the endothelial cell activation by antithrombin in vitro.
Topics: Anti-Inflammatory Agents; Antithrombins; Blotting, Western; Carbazoles; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA; Dose-Response Relationship, Drug; E-Selectin; Endothelial Cells; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Heparin; Humans; Immunohistochemistry; Immunoprecipitation; In Vitro Techniques; Indoles; Interleukin-1; Lipopolysaccharides; NF-kappa B; Nuclear Proteins; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Binding; Pyrroles; RNA, Messenger; Time Factors; Trans-Activators; Tumor Necrosis Factor-alpha; Umbilical Veins | 2004 |
Adenylyl cyclase-cAMP system inhibits thyroid hormone-stimulated osteocalcin synthesis in osteoblasts.
Topics: Adenylyl Cyclases; Adjuvants, Immunologic; Animals; Animals, Newborn; Bucladesine; Carbazoles; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Indoles; Mice; Nerve Growth Factors; Neuropeptides; Neurotransmitter Agents; Osteoblasts; Osteocalcin; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein Kinase C; Pyrroles; Triiodothyronine | 2005 |
Cyclic AMP controls BDNF-induced TrkB phosphorylation and dendritic spine formation in mature hippocampal neurons.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic beta-Agonists; Amino Acids; Analysis of Variance; Animals; Animals, Newborn; Blotting, Western; Brain-Derived Neurotrophic Factor; Carbazoles; Cell Count; Cells, Cultured; Colforsin; Cyclic AMP; Dendritic Spines; Disks Large Homolog 4 Protein; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Fluorescent Antibody Technique; Gene Expression Regulation; Green Fluorescent Proteins; Hippocampus; Immunoprecipitation; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Isoproterenol; Membrane Proteins; Microtubule-Associated Proteins; Nerve Tissue Proteins; Neurons; Phosphorylation; Protein Kinase Inhibitors; Pseudopodia; Pyrroles; Rats; Receptor, trkB; Thionucleotides; Transfection | 2005 |
Presenilin attenuates receptor-mediated signaling and synaptic function.
Topics: Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Carbamates; Carbazoles; Cell Adhesion Molecules; Cell Line, Tumor; Cell Membrane; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DCC Receptor; Dipeptides; Endopeptidases; Excitatory Postsynaptic Potentials; Genes, DCC; Glutamic Acid; Indoles; Lidocaine; Membrane Proteins; Memory; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurites; Neuroblastoma; Neurons; Piperazines; Presenilin-1; Protein Processing, Post-Translational; Pyrroles; Quinoxalines; Rats; Receptors, Cell Surface; Recombinant Fusion Proteins; Second Messenger Systems; Synaptic Transmission; Transfection; Tumor Suppressor Proteins | 2005 |
Effects of rolipram on induction of action potential bursts in central snail neurons.
Topics: Action Potentials; Animals; Carbazoles; Cell Membrane; Central Nervous System; Colforsin; Cyclic AMP; Estrenes; Ganglia, Invertebrate; Indoles; Magnesium; Neurons; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Phospholipases; Phosphoric Diester Hydrolases; Pyrroles; Pyrrolidinones; Rolipram; Signal Transduction; Snails; Synaptic Transmission | 2005 |
Excitatory actions of dopamine via D1-like receptors in the rat lateral geniculate nucleus.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Action Potentials; Adrenergic alpha-Antagonists; Analysis of Variance; Anesthetics, Local; Animals; Animals, Newborn; Benzazepines; Bromocriptine; Carbazoles; Colforsin; Cyclic AMP; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Geniculate Bodies; In Vitro Techniques; Indoles; Neurons; Patch-Clamp Techniques; Prazosin; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Tetrodotoxin; Thionucleotides | 2005 |
Forskolin-induced cell shrinkage and apical translocation of functional enhanced green fluorescent protein-human alphaENaC in H441 lung epithelial cell monolayers.
Topics: Amiloride; Biological Transport; Biotinylation; Brefeldin A; Carbazoles; Cell Line; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Epithelial Cells; Epithelial Sodium Channels; Genistein; Green Fluorescent Proteins; Humans; Immunoblotting; Immunoprecipitation; Indoles; Ions; Lung; Microscopy, Confocal; Protein Structure, Tertiary; Protein Transport; Protein-Tyrosine Kinases; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium; Sodium Channels; Transfection | 2006 |
Protein kinase A regulates the sensitivity of spinal commissural axon turning to netrin-1 but does not switch between chemoattraction and chemorepulsion.
Topics: Animals; Axons; Blotting, Western; Carbazoles; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Humans; Indoles; Nerve Growth Factors; Netrin-1; Neurons; Pyrroles; Rats; Rats, Sprague-Dawley; Spinal Cord; Time Factors; Tumor Suppressor Proteins | 2006 |
Metaplasticity of the late-phase of long-term potentiation: a critical role for protein kinase A in synaptic tagging.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electric Stimulation; Female; Hippocampus; In Vitro Techniques; Indoles; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Okadaic Acid; Pyrroles; Signal Transduction; Synapses | 2006 |
cAMP-PKA signaling pathway regulates bone resorption mediated by processing of cathepsin K in cultured mouse osteoclasts.
Topics: Animals; Antibodies; Bone Resorption; Carbazoles; Cathepsin K; Cathepsins; Cells, Cultured; Chloroquine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Indoles; Isoquinolines; Lysosomes; Mannose; Mice; Monensin; Naphthalenes; Osteoclasts; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Pyrroles; Receptor, IGF Type 2; Signal Transduction; Sulfonamides | 2006 |
Trace amine-associated receptor 1 is a modulator of the dopamine transporter.
Topics: Animals; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Indoles; Luciferases; Macaca mulatta; Methamphetamine; Methylphenidate; Phosphorylation; Protein Kinase C; Pyrroles; Receptors, G-Protein-Coupled; Stimulation, Chemical | 2007 |
Protein kinase A inhibits lysophosphatidic acid-induced migration of airway smooth muscle cells.
Topics: Actins; Amides; Animals; Bucladesine; Carbazoles; Cattle; Cell Membrane; Cell Movement; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoskeleton; Indoles; Intracellular Signaling Peptides and Proteins; Isoproterenol; Lysophospholipids; Myocytes, Smooth Muscle; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Pyridines; Pyrroles; rho-Associated Kinases; Theophylline; Trachea | 2007 |
Regulation of plasminogen activators in human thyroid follicular cells and their relationship to differentiated function.
Topics: Adenylyl Cyclases; Aprotinin; Cell Differentiation; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activators; Epidermal Growth Factor; Fibroblast Growth Factors; Flavonoids; Humans; Indoles; Insulin; Iodine; Iodine Radioisotopes; Maleimides; Mesylates; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Plasminogen Inactivators; Protein Kinase C; Protein Kinase C beta; Protein Kinase Inhibitors; Pyrroles; RNA, Messenger; Serine Proteinase Inhibitors; Signal Transduction; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Time Factors; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator | 2007 |
Regulation of the Na+/Ca2+ exchanger (NCX) in the murine embryonic heart.
Topics: Adenosine Triphosphate; Alkaline Phosphatase; Animals; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Fetal Development; Gestational Age; Heart; Heart Ventricles; Indoles; Mice; Myocytes, Cardiac; Patch-Clamp Techniques; Phosphorylation; Protein Kinase C; Pyrroles; Sodium-Calcium Exchanger; Tetradecanoylphorbol Acetate | 2007 |
Trypanosoma cruzi epimastigotes: regulation of myo-inositol transport by effectors of protein kinases A and C.
Topics: Animals; Biological Transport; Bucladesine; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Indoles; Inositol; Kinetics; Phosphorylation; Protein Kinase C; Pyrroles; Signal Transduction; Sphingosine; Staurosporine; Trypanosoma cruzi | 2007 |
Role of the cyclic-AMP/PKA cascade and of P/Q-type Ca++ channels in endocannabinoid-mediated long-term depression in the nucleus accumbens.
Topics: 4-Aminopyridine; Action Potentials; Animals; Barium Compounds; Calcium; Calcium Channel Blockers; Calcium Channels, P-Type; Cannabinoid Receptor Modulators; Carbazoles; Chlorides; Colforsin; Cyclic AMP; Electric Stimulation; Endocannabinoids; Enzyme Inhibitors; In Vitro Techniques; Indoles; Long-Term Synaptic Depression; Male; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Patch-Clamp Techniques; Potassium Channel Blockers; Pyrroles; Signal Transduction | 2008 |
PKA and ERK, but not PKC, in the amygdala contribute to pain-related synaptic plasticity and behavior.
Topics: Amygdala; Animals; Arthritis; Behavior; Butadienes; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Indoles; Male; Maleimides; Neuronal Plasticity; Neurons; Nitriles; Pain; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Thionucleotides | 2008 |
Regulation of relaxin 3 gene expression via cAMP-PKA in a neuroblastoma cell line.
Topics: Animals; Base Sequence; Brain Stem; Bucladesine; Carbazoles; Cell Line, Tumor; Colforsin; Conserved Sequence; Corticotropin-Releasing Hormone; Gene Expression; Intracellular Signaling Peptides and Proteins; Isoquinolines; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Promoter Regions, Genetic; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Relaxin; Sulfonamides | 2009 |
Inhibition of interleukin-1beta-induced matrix metalloproteinases 1 and 13 production in human osteoarthritic chondrocytes by prostaglandin D2.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aged; Antibodies; Carbazoles; Cells, Cultured; Chondrocytes; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme-Linked Immunosorbent Assay; Humans; Interleukin-1beta; Isoquinolines; Matrix Metalloproteinase 1; Matrix Metalloproteinase 13; Osteoarthritis; Prostaglandin D2; Pyrroles; Receptors, Immunologic; Receptors, Leukotriene B4; Receptors, Prostaglandin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfonamides; Th2 Cells | 2008 |
cAMP-dependent kinase does not modulate the Slack sodium-activated potassium channel.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Sequence; Animals; Calcineurin; Carbazoles; Cell Line; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Humans; Kinetics; Membrane Potentials; Models, Genetic; Nerve Tissue Proteins; Patch-Clamp Techniques; Phosphorylation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Sodium-Activated; Pyrroles; Rats; Transfection | 2009 |
Leptin enhances growth inhibition by cAMP elevating agents through apoptosis of MDA-MB-231 breast cancer cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Apoptosis; Breast Neoplasms; Carbazoles; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclin-Dependent Kinase Inhibitor p27; Female; G1 Phase; Humans; Leptin; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Signal Transduction | 2009 |
Activation of adenylate cyclase by forskolin increases the protein stability of RCAN1 (DSCR1 or Adapt78).
Topics: Adenylyl Cyclases; Calcineurin; Carbazoles; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Enzyme Activation; Half-Life; Humans; Intracellular Signaling Peptides and Proteins; Isoquinolines; Muscle Proteins; Neurons; Protein Kinase Inhibitors; Protein Stability; Pyrroles; Sulfonamides | 2009 |
Protein kinase A and regulation of neonatal Nav1.5 expression in human breast cancer cells: activity-dependent positive feedback and cellular migration.
Topics: Animals; Breast Neoplasms; Carbazoles; Cell Line, Tumor; Cell Movement; Colforsin; Cyclic AMP-Dependent Protein Kinases; Feedback, Physiological; Gene Expression Regulation, Neoplastic; Humans; Infant, Newborn; Muscle Proteins; NAV1.5 Voltage-Gated Sodium Channel; Neoplasm Invasiveness; Phosphorylation; Pyrroles; Rats; Sodium Channels; Stromal Cells; Tetrodotoxin; Up-Regulation | 2010 |
Expression of thrombin-activatable fibrinolysis inhibitor (TAFI) is up-regulated by increase in intracellular cyclic AMP levels in cultured HepG2 cells.
Topics: Base Sequence; Bucladesine; Carbazoles; Carboxypeptidase B2; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Dactinomycin; DNA Primers; Humans; Promoter Regions, Genetic; Protein Kinase Inhibitors; Pyrroles; Recombinant Proteins; RNA Processing, Post-Transcriptional; RNA Stability; RNA, Messenger; Signal Transduction; Transcription, Genetic; Transfection; Up-Regulation | 2009 |
Axonal neuregulin 1 type III activates NF-kappaB in Schwann cells during myelin formation.
Topics: Animals; Axons; Chlorocebus aethiops; Colforsin; COS Cells; Gene Deletion; Mice; Models, Biological; Myelin Sheath; Neuregulin-1; NF-kappa B; Protein Isoforms; Protein Structure, Tertiary; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Schwann Cells; Signal Transduction | 2010 |
Leptin potentiates antiproliferative action of cAMP elevation via protein kinase A down-regulation in breast cancer cells.
Topics: Antineoplastic Agents; Breast Neoplasms; Carbazoles; Cell Line, Tumor; Cell Proliferation; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Activators; Female; Humans; Leptin; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Protein Kinase Inhibitors; Pyrroles; Recombinant Proteins; Signal Transduction; STAT3 Transcription Factor; Time Factors; Up-Regulation | 2010 |
Long-term potentiation of neuronal excitation in the central nucleus of the rat amygdala revealed by imaging with a voltage-sensitive dye.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Animals, Newborn; Anisomycin; Biophysics; Calcium; Carbazoles; Colforsin; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; In Vitro Techniques; Long-Term Potentiation; Neurons; Patch-Clamp Techniques; Protein Synthesis Inhibitors; Pyrroles; Rats; Rats, Wistar; Time Factors; Valine; Voltage-Sensitive Dye Imaging | 2010 |
Dopaminergic modulation of ganglion-cell photoreceptors in rat.
Topics: 1-Methyl-3-isobutylxanthine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Actins; Animals; Carbazoles; Cells, Cultured; Colforsin; Cyclic AMP; Dopamine; Dopamine Agonists; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Gene Expression Regulation; In Vitro Techniques; Light; Light Signal Transduction; Male; Membrane Potentials; Patch-Clamp Techniques; Photic Stimulation; Photoreceptor Cells; Pyrroles; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Retina; Retinal Ganglion Cells; Rod Opsins; Sodium Channel Blockers; Tetrodotoxin; Visual Pathways | 2012 |
Potentiation of the P2X3 ATP receptor by PAR-2 in rat dorsal root ganglia neurons, through protein kinase-dependent mechanisms, contributes to inflammatory pain.
Topics: Adenosine Triphosphate; Animals; Carbazoles; Colforsin; Cyclic AMP-Dependent Protein Kinases; Ganglia, Spinal; Indoles; Inflammation; Male; Maleimides; MAP Kinase Signaling System; Membrane Potentials; Neurons; Pain; Phosphorylation; Protein Kinase C; Protein Transport; Purinergic P2X Receptor Agonists; Purinergic P2X Receptor Antagonists; Pyrroles; Rats, Sprague-Dawley; Receptor, PAR-2; Receptors, Purinergic P2X3; Tetradecanoylphorbol Acetate | 2012 |
Protein kinase A regulation of T-type Ca2+ channels in rat cerebral arterial smooth muscle.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Carbazoles; Cations, Divalent; Cerebral Arteries; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endothelial Cells; Endothelium, Vascular; Female; Gene Expression Regulation; Isoproterenol; Nickel; Nifedipine; Patch-Clamp Techniques; Pyrroles; Rats; Rats, Sprague-Dawley; Signal Transduction | 2013 |
Discrete control of TRPV4 channel function in the distal nephron by protein kinases A and C.
Topics: Animals; Calcium; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Fura-2; In Vitro Techniques; Indoles; Isoquinolines; Kidney Tubules, Collecting; Maleimides; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Morpholines; Nephrons; Perfusion; Phorbol Esters; Protein Kinase C; Protein Kinase Inhibitors; Protein Transport; Pyrroles; Signal Transduction; Sulfonamides; TRPV Cation Channels | 2013 |
cAMP-PKA inhibition of SK3 channel reduced both Ca2+ entry and cancer cell migration by regulation of SK3-Orai1 complex.
Topics: Adrenergic beta-Agonists; Azepines; Calcium; Calcium Channels; Carbazoles; Cell Line, Tumor; Cell Movement; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; HEK293 Cells; Humans; Isoproterenol; Membrane Microdomains; Niacinamide; ORAI1 Protein; Phosphodiesterase 4 Inhibitors; Protein Binding; Protein Kinase Inhibitors; Pyrroles; Small-Conductance Calcium-Activated Potassium Channels | 2014 |
Modulation of transglutaminase 2 activity in H9c2 cells by PKC and PKA signalling: a role for transglutaminase 2 in cytoprotection.
Topics: Animals; Carbazoles; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoprotection; GTP-Binding Proteins; Indoles; Protein Glutamine gamma Glutamyltransferase 2; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Transglutaminases | 2014 |
Concomitant beige adipocyte differentiation upon induction of mesenchymal stem cells into brown adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adipocytes, Beige; Adipocytes, Brown; Carbazoles; Cell Differentiation; Colforsin; Culture Media; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dexamethasone; Gene Expression Regulation; Humans; Indomethacin; Insulin; Mesenchymal Stem Cells; Mitochondria; Primary Cell Culture; Pyrroles; RNA, Small Interfering; Triiodothyronine | 2016 |
Activation of adenylate cyclase-cyclic AMP-protein kinase A signaling by corticotropin-releasing factor within the dorsolateral bed nucleus of the stria terminalis is involved in pain-induced aversion.
Topics: Adenylyl Cyclases; Animals; Carbazoles; Colforsin; Conditioning, Classical; Corticotropin-Releasing Hormone; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Male; Pain; Pyrroles; Rats; Rats, Sprague-Dawley; Septal Nuclei; Signal Transduction | 2016 |
Sunitinib specifically augments glucose-induced insulin secretion.
Topics: Aniline Compounds; Animals; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Extracellular Signal-Regulated MAP Kinases; Glucose; Indoles; Insulin; Insulin Secretion; Insulin-Like Growth Factor I; Isoquinolines; Phenylpropionates; Phosphorylation; Protein Kinase Inhibitors; Pyrroles; Rats; Signal Transduction; Sulfonamides; Sunitinib | 2017 |
Recruitment of endosomal signaling mediates the forskolin modulation of guinea pig cardiac neuron excitability.
Topics: Adenylyl Cyclases; Animals; Carbazoles; Clathrin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endosomes; Flavonoids; Guinea Pigs; Heart; Humans; MAP Kinase Signaling System; Myocardium; Neurons; Pituitary Adenylate Cyclase-Activating Polypeptide; Pyrroles; Receptors, G-Protein-Coupled; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I | 2017 |
Development of gene silencer pyrrole-imidazole polyamides targeting GSK3β for treatment of polycystic kidney diseases.
Topics: Animals; Colforsin; Cysts; Glycogen Synthase Kinase 3 beta; Imidazoles; Kidney; Mice; Nylons; Polycystic Kidney Diseases; Polycystic Kidney, Autosomal Dominant; Pyrroles | 2023 |