pyrroles has been researched along with chlorambucil in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Garbiras, BJ; Hartley, JA; Haskell, MK; Lee, M; Souhami, RL; Wyatt, MD | 1 |
| Denny, WA | 1 |
| Alvarez, D; Chou, CJ; Dervan, PB; Farkas, ME; Gottesfeld, JM; Tsai, SM | 1 |
| Bando, T; Minoshima, M; Shinohara, K; Sugiyama, H | 1 |
| Bando, T; Kashiwazaki, G; Minoshima, M; Nishijima, S; Shinohara, K; Sugiyama, H | 1 |
| Arora, PS; Dervan, PB; Gottesfeld, JM; James Chou, C; Jespersen, C; Soragni, E | 1 |
| Asamitsu, S; Bando, T; Hashiya, F; Hashiya, K; Kawamoto, Y; Kizaki, S; Sugiyama, H; Yamamoto, M | 1 |
| Bando, T; Hashiya, K; Maeda, R; Obata, S; Ohno, T; Sato, S; Sugiyama, H | 1 |
| Bando, T; Hashiya, K; Hirose, Y; Sugiyama, H | 1 |
1 review(s) available for pyrroles and chlorambucil
| Article | Year |
|---|---|
DNA minor groove alkylating agents.
Topics: Alkylating Agents; Animals; Anthramycin; Antibiotics, Antineoplastic; Benzofurans; Bisbenzimidazole; Chlorambucil; Cyclohexanecarboxylic Acids; Cyclohexenes; Distamycins; DNA; Duocarmycins; Humans; Indoles; Netropsin; Nitrogen Mustard Compounds; Pyrroles; Structure-Activity Relationship | 2001 |
8 other study(ies) available for pyrroles and chlorambucil
| Article | Year |
|---|---|
Structure-activity relationship of a series of nitrogen mustard- and pyrrole-containing minor groove-binding agents related to distamycin.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Benzoates; Benzoic Acid; Binding Sites; Cattle; Cell Death; Chlorambucil; Circular Dichroism; Cross-Linking Reagents; Distamycins; DNA; Ethidium; Humans; Nitrogen Mustard Compounds; Plasmids; Poly dA-dT; Pyrroles; Structure-Activity Relationship; Tumor Cells, Cultured | 1994 |
Small molecules targeting histone H4 as potential therapeutics for chronic myelogenous leukemia.
Topics: Alkylation; Animals; Base Sequence; Blotting, Western; Cell Cycle; Cell Proliferation; Cell Survival; Chlorambucil; Female; Histones; Humans; Imidazoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mice, Nude; Molecular Sequence Data; Nylons; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2008 |
Molecular design of sequence specific DNA alkylating agents.
Topics: Antineoplastic Agents, Alkylating; Base Sequence; Cell Survival; Chlorambucil; DNA; Humans; Imidazoles; K562 Cells; Nylons; Pyrroles | 2009 |
Comparative analysis of DNA alkylation by conjugates between pyrrole-imidazole hairpin polyamides and chlorambucil or seco-CBI.
Topics: Antineoplastic Agents, Alkylating; Cell Line, Tumor; Cell Survival; Chlorambucil; DNA; Humans; Imidazoles; Lymphocytes; Molecular Structure; Neoplasms; Nylons; Pyrroles | 2010 |
Chromatin structure determines accessibility of a hairpin polyamide-chlorambucil conjugate at histone H4 genes in pancreatic cancer cells.
Topics: Acetylation; Antineoplastic Agents, Alkylating; Cell Cycle Checkpoints; Cell Line, Tumor; Chlorambucil; Chromatin; Chromatin Immunoprecipitation; Down-Regulation; HEK293 Cells; Histones; Humans; Imidazoles; Nylons; Organ Specificity; Pancreatic Neoplasms; Pyrroles; RNA, Messenger; Transcription, Genetic | 2012 |
Sequence-specific DNA alkylation and transcriptional inhibition by long-chain hairpin pyrrole-imidazole polyamide-chlorambucil conjugates targeting CAG/CTG trinucleotide repeats.
Topics: Alkylation; Chlorambucil; DNA; Imidazoles; Nylons; Pyrroles; Structure-Activity Relationship; Transcription, Genetic; Trinucleotide Repeats | 2014 |
Molecular Characteristics of DNA-Alkylating PI Polyamides Targeting RUNX Transcription Factors.
Topics: Alkylating Agents; Alkylation; Antineoplastic Agents; Cell Line, Tumor; Chlorambucil; DNA; Humans; Imidazoles; Nylons; Protein Binding; Pyrroles; Transcription Factors | 2019 |
Evaluation of the DNA Alkylation Properties of a Chlorambucil-Conjugated Cyclic Pyrrole-Imidazole Polyamide.
Topics: Alkylation; Chlorambucil; DNA; Imidazoles; Nylons; Pyrroles | 2021 |