pyrroles has been researched along with cgp 77675 in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 13 (92.86) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Feyen, J; Glatt, M; Green, J; Jeschke, M; Missbach, M; Müller, K; Susa, M | 1 |
| Crespo, J; Luong-Nguyen, NH; Maier, R; McMaster, G; Missbach, M; Susa, M | 1 |
| Freitas, F; Jeschke, M; Majstorovic, I; Mueller, DR; Schindler, P; Susa, M; Van Oostrum, J; Voshol, H | 1 |
| Kornilova, ES; Melikova, MS; Nikol'skiĭ, NN; Zheleznova, NN | 2 |
| Chen, YH; Goodenough, DA; Jeansonne, B; Lu, Q | 1 |
| Abrahamsen, H; Andersson, Y; Christoffersen, T; Guren, TK; Susa, M; Thoresen, GH; Ødegård, J; Østby, E | 1 |
| Bologna, M; Fabbro, D; Festuccia, C; Longo, M; MacKay, AR; Migliaccio, S; Recchia, I; Rucci, N; Susa, M; Teti, A | 1 |
| Fabbro, D; Funari, A; Kneissel, M; Longo, M; Migliaccio, S; Recchia, I; Rucci, N; Susa, M; Taranta, A; Teti, A | 1 |
| Jackson, EK; Jackson, TC; Mi, Z | 1 |
| Breitenlechner, CB; Engh, RA; Greiter, E; Honold, K; Huber, R; Kairies, NA; Koch, S; Koll, H; Schäfer, W; Scheiblich, S | 1 |
| Matsumura, F; Park, S | 1 |
| Fairchild, RL; Miller, GG; Reich, MB; Zhang, Q | 1 |
| Alghisi, GC; Ponsonnet, L; Rüegg, C | 1 |
14 other study(ies) available for pyrroles and cgp 77675
| Article | Year |
|---|---|
A novel inhibitor of the tyrosine kinase Src suppresses phosphorylation of its major cellular substrates and reduces bone resorption in vitro and in rodent models in vivo.
Topics: 3T3 Cells; Animals; Bone Diseases, Metabolic; Bone Resorption; Cell Adhesion Molecules; Cell Survival; CSK Tyrosine-Protein Kinase; Cytoskeletal Proteins; Disease Models, Animal; Enzyme Inhibitors; Female; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Male; Mice; Oncogene Protein pp60(v-src); Osteoblasts; Ovariectomy; Paxillin; Phosphoproteins; Phosphorylation; Pregnancy; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; src-Family Kinases | 1999 |
Active recombinant human tyrosine kinase c-Yes: expression in baculovirus system, purification, comparison to c-Src, and inhibition by a c-Src inhibitor.
Topics: Animals; Baculoviridae; Blotting, Western; Cell Line; CSK Tyrosine-Protein Kinase; Enzyme Inhibitors; Humans; Insecta; Precipitin Tests; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-yes; Pyrimidines; Pyrroles; Recombinant Proteins; src-Family Kinases | 2000 |
Fluoroaluminate stimulates phosphorylation of p130 Cas and Fak and increases attachment and spreading of preosteoblastic MC3T3-E1 cells.
Topics: Aluminum; Amino Acid Sequence; Animals; Cell Adhesion; Cell Movement; Collagen; Crk-Associated Substrate Protein; Epidermal Growth Factor; Fluorine; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; GTP-Binding Proteins; Insulin; Lysophospholipids; Mice; Molecular Sequence Data; Osteoblasts; Pertussis Toxin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Pyrimidines; Pyrroles; Retinoblastoma-Like Protein p130; Signal Transduction; src-Family Kinases; Stem Cells; Tyrosine; Virulence Factors, Bordetella | 2002 |
[The role of Src-kinase in the regulation of endocytosis of EGF-receptor complexes. I. Dynamics of EGF internalization, recycling, sorting, and degradation during inhibition of Src-kinase activity].
Topics: Animals; Cell Line; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Kinetics; Mice; Mice, Knockout; Pyrimidines; Pyrroles; src-Family Kinases | 2001 |
[The role of Src-kinase in the regulation of endocytosis of EGF-receptor complexes. Distribution of clathrin after stimulation of EGR endocytosis in various cell lines during inhibition of Src-kinase activity].
Topics: Animals; Cell Line; Clathrin; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Fluorescent Antibody Technique, Direct; Humans; Mice; Mice, Knockout; Pyrimidines; Pyrroles; src-Family Kinases | 2001 |
Nonreceptor tyrosine kinase c-Yes interacts with occludin during tight junction formation in canine kidney epithelial cells.
Topics: Animals; Blotting, Western; Calcium; Dogs; Epithelial Cells; Gene Expression Regulation; Membrane Proteins; Microscopy, Confocal; Microscopy, Fluorescence; Occludin; Phosphorylation; Precipitin Tests; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-yes; Pyrimidines; Pyrroles; src-Family Kinases; Tight Junctions; Time Factors; Tyrosine | 2002 |
EGF receptor-mediated, c-Src-dependent, activation of Stat5b is downregulated in mitogenically responsive hepatocytes.
Topics: Animals; Cell Division; Cells, Cultured; DNA; DNA-Binding Proteins; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Growth Hormone; Hepatocytes; Male; Milk Proteins; Mitogens; Phosphorylation; Phosphoserine; Phosphotyrosine; Prolactin; Protein Binding; Proto-Oncogene Proteins pp60(c-src); Pyrimidines; Pyrroles; Rats; Rats, Wistar; STAT5 Transcription Factor; Trans-Activators; Transforming Growth Factor alpha | 2003 |
Pyrrolopyrimidine c-Src inhibitors reduce growth, adhesion, motility and invasion of prostate cancer cells in vitro.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Adhesion; Cell Division; Cell Movement; Cell Size; CSK Tyrosine-Protein Kinase; Drug Screening Assays, Antitumor; Humans; Male; Matrix Metalloproteinases; Neoplasm Invasiveness; Prostatic Neoplasms; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; src-Family Kinases; Tumor Cells, Cultured | 2003 |
Reduction of c-Src activity by substituted 5,7-diphenyl-pyrrolo[2,3-d]-pyrimidines induces osteoclast apoptosis in vivo and in vitro. Involvement of ERK1/2 pathway.
Topics: Actins; Adenocarcinoma, Clear Cell; Animals; Apoptosis; Bone Resorption; Caspases; Cell Adhesion; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Female; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Osteoclasts; Proto-Oncogene Proteins pp60(c-src); Pyrimidines; Pyrroles; Rats; Rats, Wistar | 2004 |
Modulation of cyclic AMP production by signal transduction pathways in preglomerular microvessels and microvascular smooth muscle cells.
Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Cyclic AMP; Estrenes; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Platelet Aggregation Inhibitors; Pyrimidines; Pyrroles; Pyrrolidinones; Rats; Signal Transduction | 2004 |
Crystal structures of active SRC kinase domain complexes.
Topics: Animals; Binding Sites; Crystallography, X-Ray; Humans; Models, Molecular; Molecular Sequence Data; Molecular Structure; Multienzyme Complexes; Protein Binding; Protein Structure, Tertiary; Purines; Pyrimidines; Pyrroles; src-Family Kinases | 2005 |
Characterization of anti-apoptotic action of TCDD as a defensive cellular stress response reaction against the cell damaging action of ultra-violet irradiation in an immortalized normal human mammary epithelial cell line, MCF10A.
Topics: Adaptation, Physiological; alpha 1-Antitrypsin; Apoptosis; bcl-2-Associated X Protein; Benzoflavones; Butadienes; Cell Line; DNA Fragmentation; Epidermal Growth Factor; Epithelial Cells; Female; Ferric Compounds; Flavonoids; Glutathione; Humans; Hydrogen Peroxide; Lipopolysaccharides; Mitogen-Activated Protein Kinases; Nitriles; Nitro Compounds; Phenanthrolines; Polychlorinated Dibenzodioxins; Pyrimidines; Pyrroles; Quaternary Ammonium Compounds; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transforming Growth Factor alpha; Ultraviolet Rays | 2006 |
Inhibition of Src kinases combined with CD40 ligand blockade prolongs murine cardiac allograft survival.
Topics: Animals; Antibodies; CD40 Ligand; CD8-Positive T-Lymphocytes; Graft Rejection; Graft Survival; Heart; Heart Transplantation; Mice; Mice, Inbred C57BL; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; src-Family Kinases; Transplantation, Homologous | 2005 |
The integrin antagonist cilengitide activates alphaVbeta3, disrupts VE-cadherin localization at cell junctions and enhances permeability in endothelial cells.
Topics: Animals; Antigens, CD; Cadherins; Cell Adhesion; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Enzyme Induction; Focal Adhesion Protein-Tyrosine Kinases; Humans; Integrin alphaVbeta3; Integrin beta1; Intercellular Junctions; Permeability; Phosphorylation; Pyrimidines; Pyrroles; Snake Venoms; src-Family Kinases | 2009 |