Page last updated: 2024-08-18

pyrroles and carfilzomib

pyrroles has been researched along with carfilzomib in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (13.33)29.6817
2010's11 (73.33)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
Fuchs, O; Kuzelova, K; Marinov, I; Provaznikova, D; Spicka, I1
Orlowski, RZ; Shah, JJ1
Kay, LE; Ruschak, AM; Schimmer, AD; Slassi, M1
Gallastegui, N; Groll, M1
Attkisson, E; Dasmahapatra, G; Dent, P; Fisher, RI; Friedberg, JW; Grant, S; Lembersky, D; Patel, H; Peterson, D; Son, MP1
Abe, M; Fujii, S1
Hu, Y; Wu, P; Zhang, J1
Mateos, MV; Ocio, EM; San Miguel, JF1
Kuroda, J1
Kłoczko, J; Ołdziej, AE; Romaniuk, W; Zińczuk, J1
Bocchia, M; Brambilla, CZ; Candi, V; Gozzetti, A; Papini, G; Sirianni, S1
Ma, H; Su, Z; Sun, F; Zhao, N1
Grammatico, S; Petrucci, MT; Scalzulli, E; Vozella, F1
Li, J; Sherman, DJ1
Deng, K; Ding, C; Hong, B; Li, H; Lin, WC; Liu, XL; Lui, VWY; Lv, XT; Shi, WH; Yin, YP1

Reviews

10 review(s) available for pyrroles and carfilzomib

ArticleYear
Antiproliferative and proapoptotic effects of proteasome inhibitors and their combination with histone deacetylase inhibitors on leukemia cells.
    Cardiovascular & hematological disorders drug targets, 2009, Volume: 9, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Boronic Acids; Bortezomib; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Humans; Lactones; Leukemia; Oligopeptides; Protease Inhibitors; Pyrazines; Pyrroles

2009
Proteasome inhibitors in the treatment of multiple myeloma.
    Leukemia, 2009, Volume: 23, Issue:11

    Topics: Antineoplastic Agents; Boronic Acids; Bortezomib; Humans; Lactones; Multiple Myeloma; Oligopeptides; Protease Inhibitors; Pyrazines; Pyrroles

2009
Novel proteasome inhibitors to overcome bortezomib resistance.
    Journal of the National Cancer Institute, 2011, Jul-06, Volume: 103, Issue:13

    Topics: Allosteric Site; Animals; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Cell Line, Tumor; Chloroquine; Clioquinol; Drug Resistance, Neoplasm; Humans; Hydroxyquinolines; Lactones; Neoplasms; Oligopeptides; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Pyrroles; Threonine; Ubiquitinated Proteins; Ubiquitination

2011
Clinical and marketed proteasome inhibitors for cancer treatment.
    Current medicinal chemistry, 2013, Volume: 20, Issue:20

    Topics: Boron Compounds; Boronic Acids; Bortezomib; Glycine; Humans; Lactones; Neoplasms; Oligopeptides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Pyrroles; Structure-Activity Relationship; Threonine

2013
Novel generation of agents with proven clinical activity in multiple myeloma.
    Seminars in oncology, 2013, Volume: 40, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Humans; Immunologic Factors; Lactones; Multiple Myeloma; Oligopeptides; Proteasome Inhibitors; Pyrroles; Recurrence; Thalidomide; Treatment Outcome

2013
[Current status of clinical trials of novel agents for multiple myeloma].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:10

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Drug Approval; Drug Discovery; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Lactones; Molecular Targeted Therapy; Multiple Myeloma; Oligopeptides; Pyrroles; Thalidomide; Vorinostat

2014
[Proteasome inhibitors in cancer therapy].
    Postepy higieny i medycyny doswiadczalnej (Online), 2015, Dec-31, Volume: 69

    Topics: Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Caspases; Dipeptides; Humans; Lactones; Multiple Myeloma; Neoplasms; Oligopeptides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proteolysis; Pyrroles; Thiazoles; Threonine

2015
Second Generation Proteasome Inhibitors in Multiple Myeloma.
    Anti-cancer agents in medicinal chemistry, 2017, Volume: 17, Issue:7

    Topics: Animals; Boronic Acids; Bortezomib; Central Nervous System Neoplasms; Drug Discovery; Humans; Lactones; Multiple Myeloma; Neoplasm Recurrence, Local; Oligopeptides; Proteasome Inhibitors; Pyrroles; Threonine

2017
Proteasome inhibitors for the treatment of multiple myeloma.
    Expert opinion on pharmacotherapy, 2018, Volume: 19, Issue:4

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Boron Compounds; Bortezomib; Glycine; Hematologic Diseases; Humans; Lactones; Multiple Myeloma; Neoplasm Recurrence, Local; Oligopeptides; Proteasome Inhibitors; Pyrroles

2018
Proteasome Inhibitors: Harnessing Proteostasis to Combat Disease.
    Molecules (Basel, Switzerland), 2020, Feb-05, Volume: 25, Issue:3

    Topics: Antineoplastic Agents; Boron Compounds; Bortezomib; Glycine; Humans; Lactones; Molecular Targeted Therapy; Multiple Myeloma; Oligopeptides; Proteasome Inhibitors; Proteostasis; Pyrroles

2020

Other Studies

5 other study(ies) available for pyrroles and carfilzomib

ArticleYear
Analysing properties of proteasome inhibitors using kinetic and X-ray crystallographic studies.
    Methods in molecular biology (Clifton, N.J.), 2012, Volume: 832

    Topics: Antineoplastic Agents; Boronic Acids; Bortezomib; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Lactones; Multiple Myeloma; Oligopeptides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Pyrroles; Saccharomyces cerevisiae; Threonine

2012
Obatoclax interacts synergistically with the irreversible proteasome inhibitor carfilzomib in GC- and ABC-DLBCL cells in vitro and in vivo.
    Molecular cancer therapeutics, 2012, Volume: 11, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Bcl-2-Like Protein 11; Cell Line, Tumor; Drug Synergism; Germinal Center; Histones; Humans; Indoles; Lymphoma, Large B-Cell, Diffuse; MAP Kinase Kinase 4; Membrane Proteins; Mice; Mice, Nude; Myeloid Cell Leukemia Sequence 1 Protein; Oligopeptides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Xenograft Model Antitumor Assays

2012
[Molecular targeting agents for multiple myeloma].
    Nihon rinsho. Japanese journal of clinical medicine, 2012, Volume: 70 Suppl 8

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Boron Compounds; Boronic Acids; Bortezomib; Glycine; Histone Deacetylases; Humans; Immunologic Factors; Lactones; Lenalidomide; Molecular Targeted Therapy; Multiple Myeloma; Oligopeptides; Proteasome Inhibitors; Pyrazines; Pyrroles; Thalidomide

2012
The activity and safety of novel proteasome inhibitors strategies (single, doublet and triplet) for relapsed/refractory multiple myeloma.
    Acta oncologica (Stockholm, Sweden), 2018, Volume: 57, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Boron Compounds; Glycine; Humans; Lactones; Multiple Myeloma; Neoplasm Recurrence, Local; Oligopeptides; Proteasome Inhibitors; Pyrroles; Retrospective Studies

2018
Combinations of proteasome inhibitors with obatoclax are effective for small cell lung cancer.
    Acta pharmacologica Sinica, 2021, Volume: 42, Issue:8

    Topics: Animals; Antineoplastic Agents; Apoptosis; Bortezomib; Cell Line, Tumor; Drug Synergism; Forkhead Box Protein M1; HEK293 Cells; Humans; Indoles; Lung Neoplasms; Mice, Nude; Myeloid Cell Leukemia Sequence 1 Protein; Oligopeptides; Proteasome Inhibitors; Pyrroles; Small Cell Lung Carcinoma; Up-Regulation; Xenograft Model Antitumor Assays

2021