Page last updated: 2024-08-18

pyrroles and benzofurans

pyrroles has been researched along with benzofurans in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.86)18.7374
1990's8 (22.86)18.2507
2000's12 (34.29)29.6817
2010's12 (34.29)24.3611
2020's2 (5.71)2.80

Authors

AuthorsStudies
Huang, TF; Ko, FN; Su, MJ; Teng, CM; Wang, ML; Wu, TS; Yu, SM1
Hayes, ES; Pugsley, MK; Saint, DA; Walker, MJ1
Headley, PM; Herrero, JF1
Angel, F; Chevalier, E; Dahl, SG; Friese, N; Junien, JL; Pascaud, X; Riviere, PJ1
Hughes, J; Hunter, JC; Moreton, JE; Robles, L; Rose, J; Tortella, FC1
DeCoster, MA; Tortella, FC1
Ebisu, H; Fukuda, Y; Furuta, H; Kusama, Y; Oomori, Y; Terashima, S1
Holtzman, SG; Powell, KR1
Cheng, YJ; Duh, CY; Wang, SK1
Bergman, J; Carey, GJ1
Denny, WA1
Bowen, JP; Handl, HL; Hartley, JA; Hubbard, RB; Hudson, SJ; Kiakos, K; Lee, M; Madsen, EC; Price, CA; Toth, JL1
INUBUSHI, Y; KONITA, T; MATSUMOTO, S; TSUDA, Y1
Bennani, YL; Cowart, M; Esbenshade, TA; Hancock, AA; Pratt, JK; Stewart, AO1
Ishibashi, A; Kobayashi, S; Nagai, M; Seino, K; Shikata, K; Tokuhara, N; Yamauchi, T1
Handl, HL; Hartley, JA; Kiakos, K; Lee, M; Lingerfelt, BM; Price, CA1
Baraldi, PG; Borgatti, M; Carrion, MD; Gambari, R; Heilmann, J; Iaconinoto, MA; Romagnoli, R; Tabrizi, MA1
Allen, LT; Byrne, A; Gallagher, WM; Hall, MJ; McDonnell, SO; O'Shea, DF1
Lynch, DE; Narasegowda, RS; Narasimhamurthy, T; Rathore, RS; Yathirajan, HS1
Hess, M; Lehr, M; Schulze Elfringhoff, A1
Kim, J; Kim, Y; Park, SB1
Pyne, SG; Swamy, NK; Yazici, A1
Gerard, B; Lajkiewicz, NJ; Porco, JA; Roche, SP1
Liu, J; Moonsin, P; Nguyen, TQ; Phan, H; Promarak, V; Sharenko, A; Walker, B; Zhang, Y1
Asano, K; Boyd, SA; De Meese, LA; Endo, S; Fukumoto, S; Gauthier, C; Habuka, N; Hasui, T; Matsui, H; Mizukami, A; Ohra, T; Ohyabu, N; Siedem, CS; Sogabe, S; Tang, TP1
Ichii, Y; Ito, Y; Kakiuchi, M; Miyata, O; Shono, H; Ueda, M1
Hilmy, A; Lajkiewicz, NJ; Porco, JA; Stone, SD; Whitesell, L1
Ben Ammar, H; Ben Hassine, B; Doucet, H; Hfaiedh, A; Soulé, JF; Yuan, K1
Banerjee, P; Ghosh, A; Pandey, AK1
Hartwig, JF; Nakao, Y; Schramm, Y; Semba, K; Takeuchi, M1
Li, YD; Liu, XM; Lu, Y; Qin, YH; Wu, YQ; Xia, JJ1
Bao, JK; Bao, MY; Li, JZ; Li, YY; Liang, DF; Lu, KM; Luo, H; Sun, R; Wang, X1
Chen, XY; Jiang, JF; Zhong, DF1
Morinobu, A1
Bertrand, B; Chang, L; Dechoux, L; Fischer-Durand, N; Gontard, G; Thorimbert, S1

Reviews

4 review(s) available for pyrroles and benzofurans

ArticleYear
Kappa opioids: therapeutic considerations in epilepsy and CNS injury.
    Clinical neuropharmacology, 1994, Volume: 17, Issue:5

    Topics: Analgesics, Opioid; Animals; Anticonvulsants; Benzofurans; Central Nervous System Diseases; Epilepsy; Humans; Pyrroles; Pyrrolidines; Receptors, Opioid, kappa; Thiophenes

1994
DNA minor groove alkylating agents.
    Current medicinal chemistry, 2001, Volume: 8, Issue:5

    Topics: Alkylating Agents; Animals; Anthramycin; Antibiotics, Antineoplastic; Benzofurans; Bisbenzimidazole; Chlorambucil; Cyclohexanecarboxylic Acids; Cyclohexenes; Distamycins; DNA; Duocarmycins; Humans; Indoles; Netropsin; Nitrogen Mustard Compounds; Pyrroles; Structure-Activity Relationship

2001
[Metabolic research of domestically developed small molecule tyrosine kinase inhibitors].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2016, Volume: 51, Issue:2

    Topics: Acrylamides; Aniline Compounds; Antineoplastic Agents; Benzofurans; China; Crown Ethers; Drug Interactions; Humans; Indoles; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrroles; Quinazolines

2016
JAK inhibitors for the treatment of rheumatoid arthritis.
    Immunological medicine, 2020, Volume: 43, Issue:4

    Topics: Adamantane; Antirheumatic Agents; Arthritis, Rheumatoid; Azetidines; Benzofurans; Cardiovascular Diseases; Herpes Zoster; Humans; Janus Kinases; Molecular Targeted Therapy; Neutropenia; Niacinamide; Piperidines; Protein Kinase Inhibitors; Purines; Pyrazoles; Pyrimidines; Pyrroles; Sulfonamides; Venous Thromboembolism

2020

Other Studies

31 other study(ies) available for pyrroles and benzofurans

ArticleYear
Vasorelaxing effect in rat thoracic aorta caused by fraxinellone and dictamine isolated from the Chinese herb Dictamnus dasycarpus Turcz: comparison with cromakalim and Ca2+ channel blockers.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 345, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alkaloids; Animals; Aorta, Thoracic; Benzofurans; Benzopyrans; Calcium; Calcium Channel Blockers; Cromakalim; Cyclic AMP; Cyclic GMP; Drugs, Chinese Herbal; Female; Glyburide; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Potassium Channels; Potassium Chloride; Pyrroles; Quinolines; Rats; Rats, Inbred Strains; Verapamil

1992
Do related kappa agonists produce similar effects on cardiac ion channels?
    Proceedings of the Western Pharmacology Society, 1995, Volume: 38

    Topics: Animals; Anti-Arrhythmia Agents; Benzofurans; Blood Pressure; Electric Stimulation; Electrocardiography; Heart; Heart Rate; Heart Ventricles; Ion Channels; Male; Myocardium; Pyrroles; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Stereoisomerism; Thiophenes

1995
Functional evidence for multiple receptor activation by kappa-ligands in the inhibition of spinal nociceptive reflexes in the rat.
    British journal of pharmacology, 1993, Volume: 110, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Anticonvulsants; Benzeneacetamides; Benzofurans; Blood Pressure; Decerebrate State; Male; Naloxone; Nociceptors; Piperazines; Pyrroles; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, kappa; Reflex; Spinal Cord; Thiophenes

1993
Reversal by kappa-agonists of peritoneal irritation-induced ileus and visceral pain in rats.
    Life sciences, 1997, Volume: 60, Issue:9

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetic Acid; Analgesics; Animals; Benzofurans; Benzomorphans; Cyclazocine; Fentanyl; Gastric Emptying; Intestinal Pseudo-Obstruction; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Peritoneum; Pyrroles; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Thiophenes

1997
EEG spectral analysis of the neuroprotective kappa opioids enadoline and PD117302.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 282, Issue:1

    Topics: Animals; Benzofurans; Electroencephalography; Male; Narcotics; Neuroprotective Agents; Pyrroles; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Thiophenes

1997
Novel cyclopropapyrroloindole derivative (AT-3510) bearing methoxycarbonyl and trifluoromethyl groups.
    Journal of medicinal chemistry, 1999, Apr-22, Volume: 42, Issue:8

    Topics: Animals; Antineoplastic Agents; Benzofurans; Drug Screening Assays, Antitumor; Female; Humans; Mice; Mice, Inbred BALB C; Prodrugs; Pyrroles; Stereoisomerism; Structure-Activity Relationship; Transplantation, Heterologous; Tumor Cells, Cultured

1999
Differential antagonism of the rate-decreasing effects of kappa-opioid receptor agonists by naltrexone and norbinaltorphimine.
    European journal of pharmacology, 1999, Jul-14, Volume: 377, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Behavior, Animal; Benzeneacetamides; Benzofurans; Benzomorphans; Conditioning, Operant; Dose-Response Relationship, Drug; Ethylketocyclazocine; Nalorphine; Naltrexone; Narcotic Antagonists; Pyrroles; Pyrrolidines; Receptors, Opioid, kappa; Reinforcement Schedule; Saimiri; Thiophenes

1999
Cytotoxic constituents from leaves of Aglaia elliptifolia.
    Journal of natural products, 2001, Volume: 64, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Benzene Derivatives; Benzofurans; China; Chromatography, Thin Layer; Diamide; Drug Screening Assays, Antitumor; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Plant Leaves; Plants, Medicinal; Pyrroles; Spectrophotometry, Infrared; Tumor Cells, Cultured

2001
Enadoline discrimination in squirrel monkeys: effects of opioid agonists and antagonists.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:1

    Topics: Animals; Benzofurans; Discrimination Learning; Dose-Response Relationship, Drug; Male; Nalbuphine; Naltrexone; Narcotic Antagonists; Pyrroles; Pyrrolidines; Receptors, Opioid, kappa; Receptors, Opioid, mu; Saimiri; Thiophenes

2001
Sequence selective recognition of DNA by hairpin conjugates of a racemic seco-cyclopropaneindoline-2-benzofurancarboxamide and polyamides.
    Bioorganic & medicinal chemistry letters, 2002, Aug-19, Volume: 12, Issue:16

    Topics: Alkylation; Amides; Base Sequence; Benzofurans; Binding Sites; DNA; Imidazoles; Molecular Conformation; Pyrroles; Substrate Specificity

2002
SHIHUNINE: A NEW PHTHALIDE-PYRROLIDINE ALKALOID.
    Chemical & pharmaceutical bulletin, 1964, Volume: 12

    Topics: Alkaloids; Benzofurans; Chemistry, Pharmaceutical; Lactones; Phthalic Acids; Pyrroles; Pyrrolidines; Research

1964
A new class of potent non-imidazole H(3) antagonists: 2-aminoethylbenzofurans.
    Bioorganic & medicinal chemistry letters, 2004, Feb-09, Volume: 14, Issue:3

    Topics: Amines; Animals; Benzofurans; Central Nervous System; Histamine Antagonists; Humans; Imidazoles; Molecular Structure; Piperidines; Pyrroles; Pyrrolidines; Rats; Receptors, Histamine H3; Structure-Activity Relationship

2004
Effect of E6060 [4-{5-[7-fluoro-4-(trifluoromethyl)benzo[b]furan-2-yl]-1H-2-pyrrolyl}benzoic acid], a novel subtype-selective retinoid, on lupus-like nephritis in female (NZBxNZW)F1 mice.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 312, Issue:3

    Topics: Animals; Antibodies, Antinuclear; Benzoates; Benzofurans; Blood Urea Nitrogen; Female; Immunoglobulin G; Immunoglobulin M; Interleukin-12; Kidney; Lupus Nephritis; Mice; Mice, Inbred NZB; Proteinuria; Pyrroles; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Survival Rate

2005
Sequence specific recognition of DNA by tailor-made hairpin conjugates of achiral seco-cyclopropaneindoline-2-benzofurancarboxamide and pyrrole-imidazole polyamides.
    Bioorganic & medicinal chemistry letters, 2005, Jun-15, Volume: 15, Issue:12

    Topics: Amides; Antigens, Neoplasm; AT Rich Sequence; Benzofurans; Binding Sites; DNA; DNA Topoisomerases, Type II; DNA-Binding Proteins; GC Rich Sequence; Hot Temperature; Imidazoles; Molecular Conformation; Nucleic Acid Conformation; Promoter Regions, Genetic; Pyrroles; Substrate Specificity; Thermodynamics

2005
Synthesis and biological activity of alpha-bromoacryloyl lexitropsin conjugates.
    European journal of medicinal chemistry, 2005, Volume: 40, Issue:11

    Topics: Animals; Antineoplastic Agents, Alkylating; Benzofurans; Drug Screening Assays, Antitumor; Heterocyclic Compounds; Humans; Imidazoles; Mice; Molecular Structure; Netropsin; Pyrazoles; Pyrroles; Structure-Activity Relationship; Thiophenes; Tumor Cells, Cultured

2005
Supramolecular photonic therapeutic agents.
    Journal of the American Chemical Society, 2005, Nov-30, Volume: 127, Issue:47

    Topics: Benzofurans; Boron Compounds; Electron Transport; Oxidation-Reduction; Photosensitizing Agents; Pyrroles; Substrate Specificity

2005
Conformations of three heterocyclic perhydropyrrolobenzofurans and polymeric assembly via co-operative intermolecular C-H...O hydrogen bonds.
    Acta crystallographica. Section C, Crystal structure communications, 2006, Volume: 62, Issue:Pt 5

    Topics: Benzofurans; Crystallography, X-Ray; Hydrogen Bonding; Molecular Conformation; Molecular Structure; Polymers; Pyrroles

2006
Design and synthesis of 3-pyrrol-3-yl-3H-isobenzofuran-1-ones as inhibitors of human cytosolic phospholipase A2alpha.
    Journal of enzyme inhibition and medicinal chemistry, 2008, Volume: 23, Issue:6

    Topics: Benzofurans; Blood Platelets; Drug Design; Enzyme Inhibitors; Group IV Phospholipases A2; Humans; Molecular Structure; Pyrroles; Structure-Activity Relationship

2008
Regioselective synthesis of tetrasubstituted pyrroles by 1,3-dipolar cycloaddition and spontaneous decarboxylation.
    Organic letters, 2009, Jan-01, Volume: 11, Issue:1

    Topics: Benzofurans; Crystallography, X-Ray; Cyclization; Decarboxylation; Lactones; Models, Molecular; Molecular Structure; Pyrroles; Stereoisomerism

2009
Copper-mediated cyclization-halogenation and cyclization-cyanation reactions of beta-hydroxyalkynes and o-alkynylphenols and anilines.
    The Journal of organic chemistry, 2010, May-21, Volume: 75, Issue:10

    Topics: Alkynes; Aniline Compounds; Benzofurans; Copper; Cyclization; Indoles; Molecular Structure; Phenols; Pyrroles; Stereoisomerism

2010
Enantioselective photocycloaddition of 3-hydroxyflavones: total syntheses and absolute configuration assignments of (+)-ponapensin and (+)-elliptifoline.
    Journal of the American Chemical Society, 2012, Aug-08, Volume: 134, Issue:31

    Topics: Benzofurans; Flavonoids; Heterocyclic Compounds, 3-Ring; Molecular Conformation; Oxidation-Reduction; Photochemical Processes; Pyrroles; Stereoisomerism

2012
Effects of stereoisomerism on the crystallization behavior and optoelectrical properties of conjugated molecules.
    Advanced materials (Deerfield Beach, Fla.), 2013, Jul-19, Volume: 25, Issue:27

    Topics: Benzofurans; Crystallization; Molecular Structure; Particle Size; Photochemical Processes; Pyrroles; Pyrrolidinones; Stereoisomerism; Surface Properties

2013
Design, synthesis, and structure-activity relationships of dihydrofuran-2-one and dihydropyrrol-2-one derivatives as novel benzoxazin-3-one-based mineralocorticoid receptor antagonists.
    Bioorganic & medicinal chemistry, 2013, Oct-01, Volume: 21, Issue:19

    Topics: Animals; Benzofurans; Benzoxazines; Chlorocebus aethiops; COS Cells; Crystallography, X-Ray; Drug Design; Inhibitory Concentration 50; Mineralocorticoid Receptor Antagonists; Protein Binding; Pyrroles; Structure-Activity Relationship

2013
Direct synthesis of benzofuro[2,3-b]pyrroles through a radical addition/[3,3]-sigmatropic rearrangement/cyclization/lactamization cascade.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2014, May-26, Volume: 20, Issue:22

    Topics: Benzofurans; Cyclization; Free Radicals; Oximes; Pyrroles; Pyrrolidines; Stereoisomerism

2014
Biomimetic kinetic resolution: highly enantio- and diastereoselective transfer hydrogenation of aglain ketones to access flavagline natural products.
    Journal of the American Chemical Society, 2015, Jan-14, Volume: 137, Issue:1

    Topics: Benzofurans; Biological Products; Biomimetic Materials; Crystallography, X-Ray; Heterocyclic Compounds, 3-Ring; Hydrogenation; Ketones; Kinetics; Models, Molecular; Molecular Structure; Pyrroles; Quantum Theory; Stereoisomerism

2015
Eco-friendly solvents for palladium-catalyzed desulfitative C-H bond arylation of heteroarenes.
    ChemSusChem, 2015, May-22, Volume: 8, Issue:10

    Topics: Benzofurans; Catalysis; Diethyl Pyrocarbonate; Ethers; Indoles; Palladium; Pyrroles; Solvents; Sulfones; Thiophenes

2015
Lewis Acid Catalyzed Annulation of Donor-Acceptor Cyclopropane and N-Tosylaziridinedicarboxylate: One-Step Synthesis of Functionalized 2H-Furo[2,3-c]pyrroles.
    The Journal of organic chemistry, 2015, Jul-17, Volume: 80, Issue:14

    Topics: Aziridines; Benzofurans; Catalysis; Cyclopropanes; Lewis Acids; Molecular Structure; Oxidation-Reduction; Pyrroles; Pyrrolidinones

2015
Anti-Markovnikov hydroheteroarylation of unactivated alkenes with indoles, pyrroles, benzofurans, and furans catalyzed by a nickel-N-heterocyclic carbene system.
    Journal of the American Chemical Society, 2015, Sep-30, Volume: 137, Issue:38

    Topics: Alkenes; Benzofurans; Catalysis; Furans; Indoles; Methane; Molecular Structure; Nickel; Organometallic Compounds; Pyrroles

2015
A new benzofuran derivative from Nicotiana tabacum.
    Journal of Asian natural products research, 2016, Volume: 18, Issue:8

    Topics: Antineoplastic Agents, Phytogenic; Benzofurans; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Humans; Molecular Structure; Nicotiana; Nuclear Magnetic Resonance, Biomolecular; Plant Leaves; Pyrroles

2016
In silico identification of potential inhibitors targeting Streptococcus mutans sortase A.
    International journal of oral science, 2017, Volume: 9, Issue:1

    Topics: Aminoacyltransferases; Bacterial Adhesion; Bacterial Proteins; Benzofurans; Biofilms; Computer Simulation; Cysteine Endopeptidases; Dental Caries; Pyrroles; Streptococcus mutans; Thiadiazoles

2017
A Solvent-free, Catalyst-free Formal [3+3] Cycloaddition Dearomatization Strategy: Towards New Fluorophores for Biomolecules Labelling.
    ChemSusChem, 2021, Apr-22, Volume: 14, Issue:8

    Topics: Anisoles; Benzofurans; Catalysis; Cycloaddition Reaction; Fluorescent Dyes; Heterocyclic Compounds; Hydrocarbons, Aromatic; Immunoglobulin G; Indoles; Molecular Structure; Optical Imaging; Pyrones; Pyrroles; Serum Albumin, Bovine; Solvents

2021