Page last updated: 2024-08-18

pyrroles and atogepant

pyrroles has been researched along with atogepant in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's25 (100.00)2.80

Authors

AuthorsStudies
Tepper, D1
Boinpally, R; Bondiskey, P; Colón-González, F; Dockendorf, MF; Kraft, WK; Liu, W; Matthews, CZ; Min, KC; Mixson, L; Panebianco, D; Xu, J1
Adams, AM; Brin, MF; Burstein, R; Melo-Carrillo, A; Schain, AJ; Strassman, AM1
Boinpally, R; Borbridge, L; Butler, M; Jakate, A; Periclou, A1
Boinpally, R; Borbridge, L; Butler, M; McGeeney, D; McNamee, B; Periclou, A; Yao, L1
Ailani, J; Finnegan, M; Goadsby, PJ; Guo, H; Lipton, RB; Miceli, R; Severt, L; Trugman, JM1
Ailani, J; Dabruzzo, B; Finnegan, M; Guo, H; Lipton, RB; Lu, K; Miceli, R; Schwedt, TJ; Severt, L; Silberstein, SD; Tassorelli, C; Trugman, JM1
Deeks, ED1
Boinpally, R; Butler, M; Jakate, A; Periclou, A1
Dai, Q; Meng, J; Tao, X; Wang, W; Wang, Z; Yan, Z; Zhou, Q1
Balasundaram, MK; Singh, A1
Avallone, R; Ferrari, A; Rustichelli, C1
Adams, A; Brin, MF; Burstein, R; Houle, TT; Melo-Carrillo, A; Strassman, AM1
da Silva, MRR; Dos Santos, JBR1
Harris, PWR; Hay, DL; Walker, CS1
Conway, C; Howell, BA; Siler, SQ; Watkins, PB; Woodhead, JL1
Altamura, C; Brunelli, N; Fofi, L; Marcosano, M; Vernieri, F1
Blumenfeld, AM; Dabruzzo, B; Dodick, DW; Finnegan, M; Li, Y; Lipton, RB; Lu, K; McAllister, P; Miceli, R; Pozo-Rosich, P; Severt, L; Trugman, JM1
Heinz, BA; Huang, X; Johnson, KW; Li, B; Li, X; Yu, J1
Ailani, J; Bedrin, K1
Abreu, J; Li, D; Tepper, SJ1
Ashina, M; Dabruzzo, B; Gandhi, P; Halker Singh, RB; Lipton, RB; Ma, J; McVige, J; Mechtler, L; Stokes, J; Yu, SY1

Reviews

6 review(s) available for pyrroles and atogepant

ArticleYear
Atogepant: First Approval.
    Drugs, 2022, Volume: 82, Issue:1

    Topics: Calcitonin Gene-Related Peptide Receptor Antagonists; Drug Approval; Drug Interactions; Humans; Migraine Disorders; Piperidines; Pyridines; Pyrroles; Spiro Compounds; United States; United States Food and Drug Administration

2022
The efficacy and safety of atogepant for the prophylactic treatment of migraine: evidence from randomized controlled trials.
    The journal of headache and pain, 2022, Jan-29, Volume: 23, Issue:1

    Topics: Analgesics; Humans; Migraine Disorders; Piperidines; Pyridines; Pyrroles; Randomized Controlled Trials as Topic; Spiro Compounds; Treatment Outcome

2022
Atogepant for Migraine Prevention: A Systematic Review of Efficacy and Safety.
    Clinical drug investigation, 2022, Volume: 42, Issue:4

    Topics: Analgesics; Calcitonin Gene-Related Peptide; Double-Blind Method; Headache; Humans; Migraine Disorders; Multicenter Studies as Topic; Piperidines; Pyridines; Pyrroles; Randomized Controlled Trials as Topic; Spiro Compounds; Treatment Outcome

2022
Small molecule CGRP receptor antagonists for the preventive treatment of migraine: A review.
    European journal of pharmacology, 2022, May-05, Volume: 922

    Topics: Adult; Analgesics; Calcitonin Gene-Related Peptide Receptor Antagonists; Humans; Migraine Disorders; Piperidines; Pyridines; Pyrroles; Quality of Life; Spiro Compounds

2022
Gepants - a long way to cure: a narrative review.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2022, Volume: 43, Issue:9

    Topics: Antibodies, Monoclonal; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Humans; Migraine Disorders; Piperidines; Pyridines; Pyrroles; Randomized Controlled Trials as Topic; Spiro Compounds

2022
A Brief Review of Gepants.
    Current pain and headache reports, 2023, Volume: 27, Issue:9

    Topics: Calcitonin Gene-Related Peptide Receptor Antagonists; Humans; Migraine Disorders; Pyridines; Pyrroles; Raynaud Disease

2023

Trials

9 trial(s) available for pyrroles and atogepant

ArticleYear
Atogepant Is Not Associated With Clinically Meaningful Alanine Aminotransferase Elevations in Healthy Adults.
    Clinical and translational science, 2021, Volume: 14, Issue:2

    Topics: Administration, Oral; Adult; Alanine Transaminase; Dose-Response Relationship, Drug; Double-Blind Method; Female; Healthy Volunteers; Humans; Liver; Liver Function Tests; Male; Middle Aged; Migraine Disorders; Piperidines; Placebos; Pyridines; Pyrroles; Spiro Compounds; Young Adult

2021
Single-Dose Pharmacokinetics and Safety of Atogepant in Adults With Hepatic Impairment: Results From an Open-Label, Phase 1 Trial.
    Clinical pharmacology in drug development, 2021, Volume: 10, Issue:7

    Topics: Administration, Oral; Aged; Calcitonin Gene-Related Peptide Receptor Antagonists; Female; Half-Life; Humans; Liver Diseases; Male; Middle Aged; Piperidines; Pyridines; Pyrroles; Severity of Illness Index; Spiro Compounds

2021
A Single Supratherapeutic Dose of Atogepant Does Not Affect Cardiac Repolarization in Healthy Adults: Results From a Randomized, Single-Dose, Phase 1 Crossover Trial.
    Clinical pharmacology in drug development, 2021, Volume: 10, Issue:9

    Topics: Adolescent; Adult; Area Under Curve; Calcitonin Gene-Related Peptide Receptor Antagonists; Cross-Over Studies; Double-Blind Method; Electrocardiography; Female; Humans; Long QT Syndrome; Male; Moxifloxacin; Piperidines; Pyridines; Pyrroles; Spiro Compounds; Young Adult

2021
Atogepant for the Preventive Treatment of Migraine.
    The New England journal of medicine, 2021, 08-19, Volume: 385, Issue:8

    Topics: Adolescent; Adult; Aged; Calcitonin Gene-Related Peptide Receptor Antagonists; Constipation; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Intention to Treat Analysis; Male; Middle Aged; Migraine Disorders; Nausea; Piperidines; Pyridines; Pyrroles; Spiro Compounds; Young Adult

2021
Time course of efficacy of atogepant for the preventive treatment of migraine: Results from the randomized, double-blind ADVANCE trial.
    Cephalalgia : an international journal of headache, 2022, Volume: 42, Issue:1

    Topics: Analgesics; Double-Blind Method; Humans; Migraine Disorders; Piperidines; Pyridines; Pyrroles; Spiro Compounds; Treatment Outcome

2022
Literature Commentary.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2021, 12-01, Volume: 41, Issue:4

    Topics: Aged; Aspirin; Humans; Ophthalmology; Piperidines; Pyridines; Pyrroles; Retrospective Studies; Spiro Compounds; Stroke

2021
Atogepant and sumatriptan: no clinically relevant drug-drug interactions in a randomized, open-label, crossover trial.
    Pain management, 2022, Volume: 12, Issue:4

    Topics: Adult; Area Under Curve; Cross-Over Studies; Drug Interactions; Humans; Piperidines; Pyridines; Pyrroles; Spiro Compounds; Sumatriptan

2022
Rates of Response to Atogepant for Migraine Prophylaxis Among Adults: A Secondary Analysis of a Randomized Clinical Trial.
    JAMA network open, 2022, 06-01, Volume: 5, Issue:6

    Topics: Adult; Analgesics; Double-Blind Method; Female; Humans; Male; Migraine Disorders; Piperidines; Pyridines; Pyrroles; Spiro Compounds; Treatment Outcome

2022
Patient-reported migraine-specific quality of life, activity impairment and headache impact with once-daily atogepant for preventive treatment of migraine in a randomized, 52-week trial.
    Cephalalgia : an international journal of headache, 2023, Volume: 51, Issue:8

    Topics: Calcitonin Gene-Related Peptide Receptor Antagonists; Drug Administration Schedule; Humans; Migraine Disorders; Patient Reported Outcome Measures; Piperidines; Pyridines; Pyrroles; Quality of Life; Spiro Compounds

2023

Other Studies

10 other study(ies) available for pyrroles and atogepant

ArticleYear
Gepants.
    Headache, 2020, Volume: 60, Issue:5

    Topics: Calcitonin Gene-Related Peptide Receptor Antagonists; Humans; Migraine Disorders; Piperidines; Pyridines; Pyrroles; Spiro Compounds

2020
Combined onabotulinumtoxinA/atogepant treatment blocks activation/sensitization of high-threshold and wide-dynamic range neurons.
    Cephalalgia : an international journal of headache, 2021, Volume: 41, Issue:1

    Topics: Analgesics; Animals; Botulinum Toxins, Type A; Calcitonin; Humans; Migraine Disorders; Nerve Fibers, Unmyelinated; Piperidines; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Spiro Compounds

2021
Atogepant.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2022, Jan-24, Volume: 79, Issue:3

    Topics: Analgesics; Humans; Migraine Disorders; Piperidines; Pyridines; Pyrroles; Spiro Compounds

2022
Atogepant (Qulipta) for migraine prevention.
    The Medical letter on drugs and therapeutics, 2021, Nov-01, Volume: 63, Issue:1636

    Topics: Administration, Oral; Calcitonin Gene-Related Peptide Receptor Antagonists; Drug Interactions; Humans; Migraine Disorders; Piperidines; Pyridines; Pyrroles; Receptors, Calcitonin Gene-Related Peptide; Signal Transduction; Spiro Compounds; Treatment Outcome

2021
Atogepant: an emerging treatment for migraine.
    Expert opinion on pharmacotherapy, 2022, Volume: 23, Issue:6

    Topics: Adult; Antibodies, Monoclonal; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Humans; Migraine Disorders; Piperidines; Pyridines; Pyrroles; Spiro Compounds

2022
Atogepant - an orally-administered CGRP antagonist - attenuates activation of meningeal nociceptors by CSD.
    Cephalalgia : an international journal of headache, 2022, Volume: 42, Issue:9

    Topics: Animals; Bayes Theorem; Calcitonin Gene-Related Peptide; Male; Migraine Disorders; Nerve Fibers, Unmyelinated; Nociceptors; Piperidines; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Spiro Compounds

2022
Atogepant (Qulipta®) for migraine prevention.
    Trends in pharmacological sciences, 2022, Volume: 43, Issue:8

    Topics: Analgesics; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Humans; Migraine Disorders; Piperidines; Pyridines; Pyrroles; Spiro Compounds

2022
Comparing the Liver Safety Profiles of 4 Next-Generation CGRP Receptor Antagonists to the Hepatotoxic CGRP Inhibitor Telcagepant Using Quantitative Systems Toxicology Modeling.
    Toxicological sciences : an official journal of the Society of Toxicology, 2022, 06-28, Volume: 188, Issue:1

    Topics: Azepines; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Chemical and Drug Induced Liver Injury; Computer Simulation; Drug-Related Side Effects and Adverse Reactions; Humans; Imidazoles; Piperidines; Pyridines; Pyrroles; Spiro Compounds

2022
Characterization of transit rates in the large intestine of mice following treatment with a CGRP antibody, CGRP receptor antibody, and small molecule CGRP receptor antagonists.
    Headache, 2022, Volume: 62, Issue:7

    Topics: Animals; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Charcoal; Constipation; Female; Humans; Intestine, Large; Ligands; Male; Mice; Mice, Transgenic; Piperidines; Pyridines; Pyrroles; Receptor Activity-Modifying Protein 1; Receptors, Calcitonin Gene-Related Peptide; Spiro Compounds

2022
Atogepant for migraine.
    Drugs of today (Barcelona, Spain : 1998), 2022, Volume: 58, Issue:8

    Topics: Analgesics; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Humans; Migraine Disorders; Piperidines; Pyridines; Pyrroles; Spiro Compounds

2022