pyrroles has been researched along with anthramycin in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (20.00) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 5 (33.33) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Gairola, C; Hurley, LH; Zmijewski, M | 1 |
| Artico, M; Filacchioni, G; Porretta, GC; Scalzo, M; Scicchitano, G | 1 |
| Bell, SM; Dee, A; Smith, PJ; Sykes, H | 1 |
| Davey, CL; Jenkins, TC; Jones, GB; Kamal, A; Kneale, GG; Neidle, S; Thurston, DE; Webster, GD | 1 |
| Hopfinger, AJ; Mabilia, M; Remers, WA | 1 |
| Asai, A; Mizukami, T; Nakano, H; Yano, K | 1 |
| Barcella, S; Gregson, SJ; Howard, PW; Jenkins, TC; Kelland, LR; Nakamya, A; Thurston, DE | 1 |
| Denny, WA | 1 |
| Bibby, MC; Burger, AM; Fiebig, HH; Loadman, PM; Schultz, R; Thurston, DE | 1 |
| Gerratana, B | 1 |
| Gerratana, B; Li, W; Rokita, SE; Saha, S | 1 |
| Jackson, PJ; Karu, K; Mantaj, J; Rahman, KM; Thurston, DE | 1 |
| Jackson, PJ; Mantaj, J; Rahman, KM; Thurston, DE | 1 |
| Basher, MA; Fox, KR; Jackson, PJM; Rahman, KM; Thurston, DE | 1 |
| Pedroni, J; Sakaine, G; Smits, G; Ture, A | 1 |
4 review(s) available for pyrroles and anthramycin
| Article | Year |
|---|---|
DNA minor groove alkylating agents.
Topics: Alkylating Agents; Animals; Anthramycin; Antibiotics, Antineoplastic; Benzofurans; Bisbenzimidazole; Chlorambucil; Cyclohexanecarboxylic Acids; Cyclohexenes; Distamycins; DNA; Duocarmycins; Humans; Indoles; Netropsin; Nitrogen Mustard Compounds; Pyrroles; Structure-Activity Relationship | 2001 |
Biosynthesis, synthesis, and biological activities of pyrrolobenzodiazepines.
Topics: Actinobacteria; Aminoglycosides; Anthramycin; Antineoplastic Agents, Alkylating; Benzodiazepines; DNA; Models, Molecular; Multigene Family; Pyrroles; Structure-Activity Relationship | 2012 |
From Anthramycin to Pyrrolobenzodiazepine (PBD)-Containing Antibody-Drug Conjugates (ADCs).
Topics: Anthramycin; Antibiotics, Antineoplastic; Antibodies; Benzodiazepines; Cell Proliferation; Female; Humans; Leukemia; Molecular Structure; Ovarian Neoplasms; Pyrroles | 2017 |
Isolation, chemistry, and biology of pyrrolo[1,4]benzodiazepine natural products.
Topics: Anthramycin; Antineoplastic Agents; Benzodiazepines; Biological Products; Biology; Humans; Pyrroles | 2022 |
11 other study(ies) available for pyrroles and anthramycin
| Article | Year |
|---|---|
Pyrrolo(1,4)benzodiazepine antitumor antibiotics. In vitro interaction of anthramycin, sibiromycin and tomaymycin with DNA using specifically radiolabelled molecules.
Topics: Anthramycin; Antibiotics, Antineoplastic; Benzodiazepinones; Binding Sites; Binding, Competitive; Chemical Phenomena; Chemistry; DNA; Drug Stability; Hydrogen-Ion Concentration; Models, Chemical; Polydeoxyribonucleotides; Proteins; Pyrroles; RNA; Thymus Gland | 1977 |
[Research on agents with antineoplastic activity. LXIII. Anthramycin and analogous compounds. X. Synthesis of 11-phenyl-5H-pyrrolo[2,1-c] [1,4] benzodiazepine derivatives].
Topics: Anthramycin; Antineoplastic Agents; Benzodiazepines; Benzodiazepinones; Cyclization; Hydrolysis; Indicators and Reagents; Oxidation-Reduction; Pyrroles | 1979 |
Involvement of DNA topoisomerase II in the selective resistance of a mammalian cell mutant to DNA minor groove ligands: ligand-induced DNA-protein crosslinking and responses to topoisomerase poisons.
Topics: Amsacrine; Animals; Anthramycin; Benzimidazoles; Benzodiazepinones; Cell Line; Cell Survival; Distamycins; DNA; DNA Damage; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance; Intercalating Agents; Ligands; Mice; Mitoxantrone; Mutation; Nuclear Proteins; Pyrroles | 1990 |
The non-covalent interaction of pyrrolo[2, 1-c] [1, 4]benzodiazepine-5, 11-diones with DNA.
Topics: Anthramycin; Antibiotics, Antineoplastic; Benzodiazepinones; Chemical Phenomena; Chemistry; Computer Simulation; DNA; Drug Interactions; Pyrroles; Stereoisomerism; Structure-Activity Relationship | 1990 |
Conformations of complexes between pyrrolo[1,4]benzodiazepines and DNA segments.
Topics: Anthramycin; Base Sequence; Benzodiazepinones; Chemical Phenomena; Chemistry; DNA; Models, Molecular; Molecular Conformation; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Pyrroles | 1986 |
Characterization of a duocarmycin-DNA adduct-recognizing protein in cancer cells.
Topics: Animals; Anthramycin; Antibiotics, Antineoplastic; Apoptosis; Binding, Competitive; Cattle; Cell Nucleus; DNA; DNA Adducts; DNA-Binding Proteins; Duocarmycins; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Humans; Indoles; Leucomycins; Nuclear Proteins; Oligonucleotides; Pyrroles; Ribonucleoproteins; Thymus Gland; Tumor Cells, Cultured | 1999 |
Effect of C2/C3-endo unsaturation on the cytotoxicity and DNA-binding reactivity of pyrrolo[2,1-c][1,4]benzodiazepines.
Topics: Anthramycin; Antibiotics, Antineoplastic; Benzodiazepines; Chemistry, Organic; DNA; Drug Screening Assays, Antitumor; Female; Humans; Molecular Structure; Organic Chemistry Phenomena; Ovarian Neoplasms; Pyrroles; Tumor Cells, Cultured | 2000 |
Preclinical pharmacology of the pyrrolobenzodiazepine (PBD) monomer DRH-417 (NSC 709119).
Topics: Animals; Anthramycin; Antibiotics, Antineoplastic; Benzodiazepines; Cell Proliferation; Chromatography, High Pressure Liquid; Gene Expression Profiling; Humans; Mass Spectrometry; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Pyrroles; Transplantation, Heterologous | 2007 |
Identification of the dioxygenase-generated intermediate formed during biosynthesis of the dihydropyrrole moiety common to anthramycin and sibiromycin.
Topics: Aminoglycosides; Anthramycin; Dioxygenases; Magnetic Resonance Spectroscopy; Molecular Structure; Pyrroles | 2015 |
Covalent Bonding of Pyrrolobenzodiazepines (PBDs) to Terminal Guanine Residues within Duplex and Hairpin DNA Fragments.
Topics: Anthramycin; Benzodiazepines; DNA; DNA Breaks; Guanine; Molecular Dynamics Simulation; Nucleic Acid Conformation; Pyrroles | 2016 |
Sequence-selective binding of C8-conjugated pyrrolobenzodiazepines (PBDs) to DNA.
Topics: Anthramycin; Base Sequence; Benzodiazepines; Binding Sites; Deoxyribonuclease I; DNA; DNA Footprinting; Guanine; Molecular Dynamics Simulation; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligonucleotides; Pyrroles; Spectrometry, Fluorescence; Temperature | 2017 |