pyrroles has been researched along with antalarmin in 170 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (4.12) | 18.2507 |
| 2000's | 80 (47.06) | 29.6817 |
| 2010's | 78 (45.88) | 24.3611 |
| 2020's | 5 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Chrousos, GP; Lewis, DB; Rice, KC; Torpy, DJ; Webster, EL; Zachman, EK | 1 |
| Bornstein, SR; Chrousos, GP; Igel, M; Joost, HG; Lewis, DB; Mitsiades, N; Rice, KC; Richman, SJ; Torpy, DJ; Tsokos, M; Webster, EL | 1 |
| Chan, EC; Chrousos, GP; Falconer, J; Madsen, G; Rice, KC; Smith, R; Webster, EL | 1 |
| Chrousos, GP; Deak, T; Ehrlich, AL; Gold, PW; Licinio, J; Maier, SF; Nguyen, KT; Spencer, RL; Watkins, LR; Webster, E; Wong, ML | 1 |
| Martinez, V; Nozu, T; Rivier, J; Taché, Y | 1 |
| Grigoriadis, DE; Heinrichs, SC; McCarthy, JR | 1 |
| Bornstein, S; Chrousos, GP; Ehrhart-Bornstein, M; Gold, PW; Licinio, J; Park, CS; Phu, P; Rice, KC; Spokes, H; Webster, EL; Wong, ML | 1 |
| Kirby, LG; Rice, KC; Valentino, RJ | 1 |
| Bornstein, SR; Chrousos, GP; Goretzki, PE; Hiroi, N; Päth, G; Scherbaum, WA; Willenberg, HS | 1 |
| Atkinson, AJ; Champoux, M; Chrousos, GP; Contoreggi, C; Gold, PW; Habib, KE; Higley, JD; Listwak, S; McCann, SM; Pushkas, J; Rice, KC; Schulkin, J; Suomi, SJ; Webster, EL; Weld, KP | 1 |
| Baird, TJ; Briscoe, RJ; Cabrera, CL; Rice, KC; Woods, JH | 1 |
| Chrousos, GP; Coukos, G; Coutifaris, C; Gravanis, A; Kalantaridou, S; Makrigiannakis, A; Margioris, AN; Rice, KC; Zoumakis, E | 1 |
| Barrientos, RM; Chrousos, GP; Contoreggi, C; Gabry, KE; Gold, PW; Isaac, MG; Ligier, S; McCarthy, EF; Rice, KC; Sternberg, EM; Webster, EL | 1 |
| Chrousos, GP; Gabry, KE; Gold, PW; McCann, SM; Mostafa, RM; Negrao, AB; Rice, KC; Sternberg, E; Webster, EL | 1 |
| Canny, BJ; Chan, EC; Chrousos, GP; Smith, R; Veldhuis, JD; Young, IR | 1 |
| Anton, PM; Karalis, K; Liu, J; Mykoniatis, A; Pan, A; Pothoulakis, C; Venihaki, M; Wang, CC; Wlk, M; Zacks, J; Zhao, D | 1 |
| Koob, GF; Markou, A; Nozulak, J; Valdez, GR; Zorrilla, EP | 1 |
| Agelaki, S; Gravanis, A; Margioris, AN; Tsatsanis, C | 1 |
| Broadbear, JH; Rice, KC; Winger, G; Woods, JH | 1 |
| Commons, KG; Peoples, A; Roche, M; Valentino, RJ | 1 |
| Lawrence, AJ; Lodge, DJ | 2 |
| Desvignes, C; Mons, G; Rodier, D; Rouquier, L; Soubrié, P; Souilhac, J; Steinberg, R | 1 |
| Belzung, C; Ducottet, C; Griebel, G | 1 |
| Bale, TL; Vale, WW | 1 |
| Chrousos, G; Gravanis, A; Kalantaridou, S; Makrigiannakis, A; Zoumakis, E | 2 |
| Curtis, AL; Pernar, L; Rivier, JE; Vale, WW; Valentino, RJ | 1 |
| Broadbear, JH; Rice, KC; Rivier, JE; Winger, G; Woods, JH | 1 |
| Crowe, PD; Grigoriadis, DE; Hoare, SR; Ling, N; Schwarz, DA; Sullivan, SK; Vale, WW | 1 |
| Gounko, NV; Gramsbergen, A; IJkema-Paassen, J; Metzger, F; Swinny, JD; van der Want, JJ | 1 |
| Cador, M; Koob, GF; Stinus, L; Zorrilla, EP | 1 |
| Pfeffer, LM; Slominski, AT; Zbytek, B | 1 |
| Chrousos, GP; Kalantaridou, SN; Makrigiannakis, A; Zoumakis, E | 1 |
| Ashkenazi, S; Chrousos, GP; Ovadia, H; Weizman, A; Yuhas, Y | 1 |
| Carey, GJ; Gold, LH; Nielsen, DM | 1 |
| Ayala, AR; Calis, KA; Chrousos, GP; Cizza, G; Gerald, M; Gold, PW; Higley, JD; Lindell, S; Pacak, K; Pushkas, J; Rice, KC; Ronsaville, D | 1 |
| Ma, S; Morilak, D; Russell, JA; Shipston, MJ | 1 |
| Chen, WK; Lumley, LA; Meyerhoff, JL; Rice, KC; Robison, CL; Saviolakis, GA | 1 |
| Houshyar, H; Hsin, LW; Jutkiewicz, EM; Rice, KC; Wood, SK; Woods, JH | 1 |
| Cizza, G; Fox, SD; Issaq, HJ; Roman, JM; Veenstra, TD | 1 |
| Gibson, M; Greenwood Van-Meerveld, B; Myers, DA; Schulkin, J | 1 |
| Cochrane, S; Greenwood-Van Meerveld, B; Johnson, AC; Myers, DA; Schulkin, J | 1 |
| Adelson, DA; Bayati, A; Chrousos, GP; Gauthier, A; Maillot, C; Mattsson, H; Million, M; Nozu, T; Rivier, J; Taché, Y | 1 |
| Card, K; Chen, F; Finkelstein, DI; Horne, MK; Krstew, EV; Lawrence, AJ; Lodge, DJ; Parish, CL | 1 |
| Challis, JR; Li, W | 1 |
| Armando, I; Bregonzio, C; Juorio, A; Macova, M; Pavel, J; Saavedra, JM; Sanchez-Lemus, E | 1 |
| Epstein, DH; Ghitza, UE; Gray, SM; Rice, KC; Shaham, Y | 1 |
| Ganesh, A; Grigoriadis, DE; Hale, L; Kiddoo, DA; Leiser, SC; Valentino, RJ; Zderic, S | 1 |
| Fischbach, PS; Rice, KC; Savit, AZ; Verhoeven, RE; Wood, SK; Woods, JH | 1 |
| Card, K; Djouma, E; Lawrence, AJ; Lodge, DJ | 1 |
| Brown, BE; Choi, EH; Crumrine, D; Demerjian, M; Elias, PM; Feingold, KR; Mauro, T | 1 |
| Funk, CK; Koob, GF; Lee, MJ; Rice, KC; Zorrilla, EP | 1 |
| Cottone, P; Koob, GF; Lee, MJ; Rice, KC; Sabino, V; Steardo, L; Zorrilla, EP | 1 |
| Berger, H; Beyermann, M; Bienert, M; Heinrich, N; Wietfeld, D | 1 |
| Graziani, G; Muzi, A; Navarra, P; Pozzoli, G; Tentori, L; Tringali, G; Vergati, M | 1 |
| Martinez, V; Taché, Y | 1 |
| Chrousos, GP; Gold, PW; Rice, KC; Zoumakis, E | 1 |
| Mello, NK; Mendelson, JH; Negus, SS; Rice, KC | 1 |
| Fimmel, S; Glass, E; Krause, K; Schnitger, A; Zouboulis, CC | 1 |
| Golab, M; Skwarlo-Sonta, K | 1 |
| Akkaraju, GR; Boehm, GW; Day, CE; Kohman, RA; Paquet, A; Sparkman, NL; Tarr, AJ | 1 |
| Fite, JE; Fix, H; French, JA; Jensen, H; Jones, B; Maxwell, H; Oparowski, K; Pacer, M; Power, ML; Rukstalis, MR; Schulkin, J | 1 |
| Chu, K; Cole, M; Koob, GF; Roberts, AJ; Zorrilla, EP | 1 |
| Lee, KF; Rissman, RA; Sawchenko, PE; Vale, W | 1 |
| Miranda, A; Nordstrom, E; Sengupta, JN; Smith, C | 1 |
| Funk, D; Harding, S; Juzytsch, W; Lê, AD; Marinelli, PW; Rice, KC; Shaham, Y | 1 |
| Amano, T; Ariga, H; Ishida, T; Kimura, T; Matsueda, K; Tajiri, H; Torii, A; Uehara, H; Yamato, S | 1 |
| Forster, GL; Lukkes, JL; Renner, KJ; Summers, CH | 1 |
| Reyes, BA; Valentino, RJ; Van Bockstaele, EJ | 1 |
| Boutrel, B; Koob, GF; O'Dell, LE; Specio, SE; Wee, S; Zorrilla, EP | 1 |
| Calis, KA; Charney, DS; Cizza, G; Contoreggi, C; Curry, PT; Glaze, ER; Gold, PW; Harder, JB; Horn, TL; Johnson, WD; McCormick, DL; Mellick, PW; Morrissey, RL; Parchment, RE; Rice, KC; Tomaszewski, JE | 1 |
| Glaze, E; Jain, P; Karlage, KL; Machatha, SG; Mogalian, E; Myrdal, PB; Narazaki, R; Sanghvi, R; Tabibi, SE; Yalkowsky, SH | 1 |
| Ness, TJ; Robbins, MT | 1 |
| Burke, AR; Forster, GL; Lowry, CA; Mouw, NJ; Pringle, RB; Renner, KJ; Summers, CH; Vuong, SM; Watt, MJ | 1 |
| Negus, SS; Rice, KC | 1 |
| Adamik, A; Telegdy, G | 1 |
| Døving, KB; Höglund, E; Lastein, S; Overli, O | 1 |
| Chotiwat, C; Harris, RB | 1 |
| Futami, Y; Izumi, T; Matsumoto, M; Ohmura, Y; Togashi, H; Yamaguchi, T; Yoshida, T; Yoshioka, M | 1 |
| Bagosi, Z; Földesi, I; Jászberényi, M; Szabó, G; Telegdy, G; Thurzó, B | 1 |
| D'Anna, KL; Gammie, SC | 1 |
| Chowen, JA; de Lecea, L; Frago, LM; Huitron-Resendiz, S; Pañeda, C; Picetti, R; Roberts, AJ | 1 |
| Arai, K; Iwasaki-Sekino, A; Mano-Otagiri, A; Ohata, H; Shibasaki, T | 1 |
| Banerjee, A; Bathgate, RA; Gundlach, AL; Ma, S; Shen, PJ | 1 |
| Arregi, A; Azpiroz, A; Beitia, G; Garmendia, L; Vegas, O | 1 |
| Blendy, JA; Briand, L; Cleck, JN; Ecke, L; Kreibich, AS; Rice, KC | 1 |
| Kalantaridou, SN; Makrigiannakis, A; Zoumakis, E | 1 |
| Berrendero, F; de Lecea, L; Maldonado, R; Martín-García, E; Plaza-Zabala, A | 1 |
| Cheng, H; Du, F; Feng, G; Liu, Z; Shi, M; Wu, Z; Xu, X; Yin, L; Zhang, G; Zhao, G | 1 |
| Rose, JC; Valego, NK | 1 |
| Bansod, K; Bhutada, P; Mundhada, D; Mundhada, Y; Quazi, M; Ubgade, A; Umathe, S | 1 |
| Boyko, M; Dubilet, M; Klin, Y; Kotz, R; Ohayon, S; Shapira, Y; Teichberg, VI; Zlotnik, A | 1 |
| Gougoura, S; Koukoulis, GN; Liakos, P | 1 |
| Gkountelias, K; Javitch, JA; Liapakis, G; Papadokostaki, M | 1 |
| Cameron, JL; Herod, SM; Pohl, CR | 1 |
| Androulidaki, A; Arranz, A; Dermitzaki, E; Gomariz, RP; Margioris, AN; Mol, B; Rassouli, O; Ripoll, J; Stathopoulos, EN; Tsatsanis, C; Venihaki, M | 1 |
| Backström, T; Johansson, V; Pettersson, A; Winberg, S | 1 |
| Bledsoe, AC; Forster, GL; Oliver, KM; Scholl, JL | 1 |
| Bhargava, A; Li, Q; Liao, M; Liu, L; Mehta, K; Pasricha, PJ; Sapolsky, R | 1 |
| Gianoulakis, C; Lam, MP | 2 |
| Ohata, H; Shibasaki, T | 1 |
| Baker, DA; Blacktop, JM; Ferda, N; Graf, EN; Lee, G; Mantsch, JR; Seubert, C | 1 |
| Ohata, H; Shibasaki, T; Takahashi, C | 1 |
| Abd El-Aziz, SM; Abdel-Wahab, BA | 1 |
| Ciccocioppo, R; Cippitelli, A; Damadzic, R; Eskay, RL; Heilig, M; Singley, E; Thorsell, A | 1 |
| Ambrozewicz, MA; Liu, X; Sanford, LD; Tang, X; Wellman, LL; Yang, L | 1 |
| Abid Masood, M; Bazin, M; Bunnage, ME; Fancy, SA; Farrant, E; Morao, I; Peakman, T; Perez, M | 1 |
| Akimoto, K; Hasegawa, G; Kageyama, K; Suda, T; Tamasawa, N; Yamagata, S | 1 |
| Aimiuwu, O; Friedman, TC; Gomez, R; Liu, Y; Lutfy, K; Mangubat, M; Nerio, N; Shin, CS | 1 |
| Cui, X; Gao, L; Gu, H; Li, Y; Lv, C; Ni, X; Xu, C | 1 |
| Henderson, LP; Oberlander, JG | 1 |
| Justice, NJ; Lee, AR; Rice, KC; Rissman, RA; Sawchenko, PE; Staup, MA; Vale, W | 1 |
| Chen, Y; Ni, X; Sheng, H; Xu, Y; Zhang, Y | 1 |
| Bhutada, PS; Mundhada, YR; Umathe, SN | 1 |
| Gao, L; Gu, H; Hu, T; Liu, J; Liu, W; Ni, X; Tao, Y; Xu, C; You, X | 1 |
| Franci, CR; Traslaviña, GA | 1 |
| Batalha, VL; Coelho, JE; Diógenes, MJ; Ferreira, DG; Gomes, R; Lopes, LV; Sebastião, AM; Valadas, JS | 1 |
| Homma, I; Onimaru, H; Suzuki, H; Takeyama, Y; Tanabe, A | 1 |
| Chen, XQ; Du, JZ; Fan, JM; Hao, K; Wang, X; Yuan, Y | 1 |
| Anagnostou, E; Chrousos, GP; Dinopoulou, V; Drakakis, P; Loutradis, D; Makrigiannakis, A; Mavrogianni, D; Partsinevelos, GA | 1 |
| Agrogiannis, G; Elkouris, M; Karalis, KP; Kemerli, M; Koutmani, Y; Patsouris, E; Politis, PK; Remboutsika, E | 1 |
| Ambrozewicz, MA; Machida, M; Sanford, LD; Wellman, LL; Yang, L | 1 |
| Carr, JA; Gao, M; Garcia, C; Li, W; Lustgarten, J; Smith, EE; Wages, M; Zhang, B | 1 |
| Arregi, A; Azpiroz, A; Garmendia, L; Gómez-Lázaro, E; Pérez-Tejada, J; Vegas, O | 1 |
| Gershon, E; Vale, WW | 1 |
| Li, JS; Mei, YY | 1 |
| de la Tremblaye, PB; Merali, Z; Milot, MR; Plamondon, H; Raymond, J | 1 |
| Bittencourt, JC; Céspedes, IC; Nascimento, JO; Viana, MB; Vicentini, JE | 1 |
| Chen, X; Kirouac, GJ; Li, S | 1 |
| Baker, DA; Lim, Y; Makky, K; Mantsch, JR; McReynolds, JR; Thao, M; Vranjkovic, O | 1 |
| Fang, X; Jin, L; Li, C; Li, R; Li, S; Sun, Z | 1 |
| Foris, L; Jászberényi, M; Telegdy, G | 1 |
| Cordomi, A; Gkountelias, K; Liapakis, G; Logothetis, DE; Margioris, AN; Matsoukas, MT; Mavromoustakos, T; Papadokostaki, M; Pardo, L; Spyridaki, K | 1 |
| Akhtar, S; Csernansky, JG; Dong, H; Li, F; Meltzer, HY; Montalvo-Ortiz, J; Rice, KC; Shi, J; Tucker, C; Wang, S; Zeng, Z | 1 |
| Bittencourt, JC; Céspedes, IC; Nascimento, JO; Pereira, BA; Silva, MS; Viana, MB | 1 |
| Coen, K; Funk, D; Lê, AD | 1 |
| Sergio, Tde O; Spiacci, A; Zangrossi, H | 1 |
| Ayanwuyi, LO; Barbier, E; Carvajal, F; Ciccocioppo, R; Cippitelli, A; Domi, E; Heilig, M; Lerma-Cabrera, JM; Li, H; Roberto, M; Scuppa, G; Ubaldi, M | 1 |
| Buckley, MM; Dinan, TG; O'Halloran, KD; O'Malley, D; Rae, MG | 1 |
| Jia, J; Li, JT; Liao, XM; Liu, R; Schmidt, MV; Si, TM; Su, YA; Uribe-Mariño, A; Wang, XD; Xie, XM; Yang, XD | 1 |
| Higgins, M; Johnson, ZP; Moore, CJ; Toufexis, D; Wilson, ME | 1 |
| Cosme, CV; Gutman, AL; LaLumiere, RT | 1 |
| Cao, C; Jin, L; Li, C; Li, S; Wang, X; Yuan, J; Zhu, C | 1 |
| Csabafi, K; Lipták, N; Szabó, G; Szakács, J | 1 |
| Chang, M; Han, RW; Jiang, JH; Li, MS; Peng, YL; Wang, P; Wang, R; Xue, HX; Zhang, PJ | 1 |
| Dawe, GS; Farooq, U; Rajkumar, R; Tan, WH; Wu, Y | 1 |
| Li, JT; Liao, XM; Liu, R; Si, TM; Su, YA; Wang, XD; Xie, XM; Yang, XD | 1 |
| Maguire, J; Mody, I | 1 |
| Aurelian, L; Bell, KA; Cook, J; Gondré-Lewis, MC; June, HL; Lüddens, H; Rabe, H; Tiruveedhula, VV; Wang, H; Warnock, KT | 1 |
| Aebischer, B; Akboga, MK; Akdamar, G; Alcalay, RN; Álvarez-Pérez, S; Aydogdu, S; Balci, KG; Barcaro, G; Bišová, K; Blanco, JL; Brewer, SH; Caruthers, SD; Ceylan, O; Chadwick, JA; Chang, DD; Che, JM; Chen, QQ; Chen, W; Chen, Z; Chung, M; Chung, W; Colecraft, HM; Coteli, E; Dogan, H; Dong, S; Elsig, S; Fahn, S; Fang, XJ; Feng, MG; Fenlon, EE; Floyd, KT; Fokdal, L; Ford, B; Fortunelli, A; Freudenberg, R; Gan-Or, Z; García, ME; Gillham, C; Giovannelli, D; Goertz, RS; Gulati, V; Haie-Meder, C; Hao, YY; Hatano, K; Hines, KJ; Hines, SM; Hirakawa, H; Hoskin, P; Hu, JH; Huang, P; Huang, Y; Hubicka, U; Inoue, Y; Ishii, N; Janssen, PM; Jin, Z; Johnson, A; Jürgenliemk-Schultz, I; Kaineder, K; Kamei, K; Kang, U; Karatas, F; Kash, TL; Katayama, Y; Keupp, J; Kirisits, C; Kisacik, H; Kodama, K; Kotzerke, J; Kryczyk, A; Kuhness, D; Kuo, S; Lanza, GM; Le Bris, N; Levin, DE; Levy, OA; Li, B; Li, H; Li, X; Liang, GD; Liang, Y; Liao, RQ; Lin, JT; Lindegaard, JC; Liong, C; Liu, B; Liu, C; Liu, GH; Liu, L; Liu, Q; Liu, X; Lowe, J; Lowery-Gionta, EG; Ma, YH; Maden, O; Mankad, V; Marder, KS; Marshall, SA; Martínez-Nevado, E; Maucksch, U; Mazeron, R; Mazzone, CM; Mazzoni, P; Mezricky, D; Mizokami, Y; Naumann, A; Navarro, M; Netzer, FP; Neurath, MF; Nie, Q; Oliva, P; Ozeke, O; Peláez, T; Pfeifer, L; Pleil, KE; Pomp, S; Pötter, R; Puckerin, AA; Rafael-Fortney, JA; Raman, SV; Rastogi, N; Řezanka, M; Řezanka, T; Rinker, JA; Rouleau, GA; Runge, R; Sahin, MD; Sakai, A; Schmieder, AH; Schmitz, AJ; Schultz, EJ; Šegedin, B; Sementa, L; Shen, Y; Shiotsuki, I; Shirahama, M; Staley, J; Starovoytov, V; Sterrer, M; Strobel, D; Sturdza, A; Subramanyam, P; Surnev, S; Swager, SA; Taeymans, J; Tan, H; Tan, LT; Tanderup, K; Temizhan, A; Terao, T; Thiele, TE; Tran, T; Tucker, MJ; Vetriani, C; Vítová, M; Wang, JP; Wang, L; Wang, M; Wang, X; Waters, CH; Weng, SX; Wickline, SA; Wildner, D; Wodarcyk, AJ; Wolf, P; Wu, L; Wu, YL; Wunderlich, G; Xiong, L; Xu, P; Yang, GS; Yang, XN; Yang, Y; Yayla, C; Ying, SH; Zachleder, V; Zhang, XG; Zhang, XK; Zhang, Y; Zheng, JY; Zhong, WZ; Zhu, J; Zhu, YJ; Żmudzki, P | 1 |
| Asok, A; Rosen, JB; Schulkin, J | 1 |
| Bagosi, Z; Csabafi, K; Czébely-Lénárt, A; Jászberényi, M; Karasz, G; Telegdy, G | 1 |
| Chen, X; Chen, Y; Guo, Y; He, D; Qiu, D; Wang, J; Xia, C; Yan, X; Zeng, M | 1 |
| Benoit, SM; de la Tremblaye, PB; Plamondon, H; Schock, S | 1 |
| Bhat, S; Georgiou, P; Gould, TD; McCarthy, MM; Merchenthaler, IJ; Tracy, JK; Zanos, P | 1 |
| Csernansky, J; Dong, H; Gallardo, C; Hong, E; Keegan, JM; Montalvo-Ortiz, J; Rice, KC; Wang, B | 1 |
| Fitzpatrick, ME; Machida, M; Sanford, LD; Sutton, AM; Wellman, LL; Williams, BL | 1 |
| Beierlein, M; Chan, CS; Dasgupta, R; Hunt, AJ; Jiang, Z; Justice, NJ; Rajamanickam, S | 1 |
| Alderman, SL; Bernier, NJ; Fuzzen, MLM; Leishman, EM | 1 |
| Krząścik, P; Lehner, M; Maciejak, P; Płaźnik, A; Skórzewska, A; Sobolewska, A; Szyndler, J; Turzyńska, D; Wisłowska-Stanek, A | 1 |
| Appleyard, CB; Flores, I; Rivera-Lopez, LL; Torres-Reverón, A | 1 |
| Bashiri, H; Kosari-Nasab, M; Sadeghi, T; Salari, AA; Shokouhi, G | 1 |
| Aoki, Y; Inamura, S; Ito, H; Matsuta, Y; Seki, M; Taga, M; Yokoyama, O; Zha, XM | 1 |
| Appleyard, CB; Gorabi, V; Rana, M; Rivera-Lopez, LL; Torres-Reverón, A | 1 |
| Bernier, NJ; Williams, TA | 1 |
| Chen, P; Chen, R; Han, Z; Kuang, L; Lv, Y; Solanki, B; Tao, F; Yao, Y; Zhou, W | 1 |
| Christian, RJ; Fuchs, RA; Galliou, JMC; Grogan, SR; Ibarra, CK; Qi, S; Ritchie, JL; Savenkova, MI; Walters, JL | 1 |
| Feng, Y; Li, Y; Liu, L; Liu, X; Liu, Y; Wang, L; Wu, Q; Zhang, L | 1 |
8 review(s) available for pyrroles and antalarmin
| Article | Year |
|---|---|
Recent advances with the CRF1 receptor: design of small molecule inhibitors, receptor subtypes and clinical indications.
Topics: Animals; Anxiety; Depression; Drug Design; Humans; Kinetics; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Seizures; Substance-Related Disorders | 1999 |
Uterine and embryonic trophoblast CRH promotes implantation and maintenance of early pregnancy.
Topics: Animals; Apoptosis; Cells, Cultured; Corticotropin-Releasing Hormone; Embryo Implantation; Endometrium; Female; Gestational Age; Humans; Pregnancy; Pregnancy, Animal; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Sensitivity and Specificity; Stromal Cells; Trophoblasts | 2003 |
Participation of maternal and fetal CRH in early phases of human implantation: the role of antalarmin.
Topics: Animals; Corticotropin-Releasing Hormone; Embryo Implantation; Female; Humans; Pregnancy; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone | 2004 |
Reproductive functions of corticotropin-releasing hormone. Research and potential clinical utility of antalarmins (CRH receptor type 1 antagonists).
Topics: Animals; Corticotropin-Releasing Hormone; Embryo Implantation; Estrogens; Fas Ligand Protein; fas Receptor; Female; Glucocorticoids; Humans; Hypothalamo-Hypophyseal System; Membrane Glycoproteins; Mice; Models, Biological; Parturition; Pituitary-Adrenal System; Placenta; Pregnancy; Pyrimidines; Pyrroles; Rats; Receptors, Corticotropin-Releasing Hormone; Reproduction | 2004 |
CRF1 receptors as a therapeutic target for irritable bowel syndrome.
Topics: Animals; Brain; Corticotropin-Releasing Hormone; Gastrointestinal Motility; Gastrointestinal Tract; Hormone Antagonists; Humans; Hyperalgesia; Intestinal Mucosa; Irritable Bowel Syndrome; Peptide Fragments; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Stress, Psychological; Urocortins | 2006 |
Potential uses of corticotropin-releasing hormone antagonists.
Topics: Animals; Anxiety; Corticotropin-Releasing Hormone; Depression; Humans; Macaca; Mood Disorders; Neurodegenerative Diseases; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Urocortins | 2006 |
CRH-like peptides in human reproduction.
Topics: Amino Acid Sequence; Corticotropin-Releasing Hormone; Female; Humans; Molecular Sequence Data; Pregnancy; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Reproduction; Urocortins | 2009 |
Topics: AC133 Antigen; Acenaphthenes; Acer; Acrosome Reaction; Adult; Agaricales; Aged; Aged, 80 and over; Animals; Animals, Zoo; Anti-Bacterial Agents; Anticoagulants; Antifungal Agents; Antimanic Agents; Antioxidants; Aortic Valve; Area Under Curve; ATP Binding Cassette Transporter, Subfamily G, Member 2; Bacillus; Bacterial Toxins; Bacterial Typing Techniques; Base Composition; Beauveria; Binge Drinking; Biomarkers; Bipolar Disorder; Blood Coagulation; Blotting, Western; Brachytherapy; Calcium Channels, L-Type; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Wall; Cells, Cultured; Ceramics; Chi-Square Distribution; China; Chlorophyll; Chlorophyta; Chloroplasts; Cholesterol, HDL; Chromatography, High Pressure Liquid; Chromobacterium; Clostridium perfringens; Clozapine; Constriction, Pathologic; Coronary Artery Bypass; Corticotropin-Releasing Hormone; Cross-Sectional Studies; Cytochrome P-450 CYP2C9; Dental Porcelain; Dental Restoration Failure; Dental Stress Analysis; Designer Drugs; Diaminopimelic Acid; DNA Fingerprinting; DNA, Bacterial; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Dosage Calculations; Drug Evaluation, Preclinical; Drug Resistance, Bacterial; Elasticity Imaging Techniques; Epsilonproteobacteria; Equipment Design; Ericaceae; Excitatory Amino Acid Antagonists; False Negative Reactions; Fatty Acids; Female; Food Analysis; Fresh Water; Gene Expression Regulation, Neoplastic; Glutathione; Graft Occlusion, Vascular; Heart Valve Prosthesis Implantation; Heart Ventricles; HEK293 Cells; Hemolymph; Humans; Hyaluronan Receptors; Hydrogen Peroxide; Hydrothermal Vents; Indoles; Inflammation Mediators; Inhibitory Concentration 50; Insecta; International Normalized Ratio; Isotope Labeling; Itraconazole; Kidney; Kinetics; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lamotrigine; Lanthanoid Series Elements; Limit of Detection; Linear Models; Lipid Peroxidation; Liver; Liver Cirrhosis; Logistic Models; Lung Neoplasms; Lymph Node Excision; Lymphatic Metastasis; Male; Malondialdehyde; Mediastinum; Metronidazole; Mice; Mice, Nude; Mice, Transgenic; Microbial Sensitivity Tests; Microscopy, Fluorescence; Middle Aged; Monocytes; Monomeric GTP-Binding Proteins; Multivariate Analysis; Myocytes, Cardiac; Neoplasm Staging; Neoplastic Stem Cells; Neural Pathways; Nitrates; Nucleic Acid Hybridization; Octamer Transcription Factor-3; Odds Ratio; Oxidation-Reduction; Oxidative Stress; Peptidoglycan; Phantoms, Imaging; Pharmacogenetics; Pharmacogenomic Variants; Phenotype; Phospholipids; Photolysis; Photosynthesis; Phylogeny; Plant Extracts; Polychaeta; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Positron Emission Tomography Computed Tomography; Predictive Value of Tests; Preoperative Care; Prostatic Neoplasms; Pseudomonas aeruginosa; Pyrimidines; Pyrroles; Quorum Sensing; Radiology, Interventional; Radiopharmaceuticals; Radiotherapy Dosage; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Reference Values; Regression Analysis; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; Rhizosphere; Risk Factors; RNA, Ribosomal, 16S; ROC Curve; Rutin; Saphenous Vein; Seawater; Selenium; Semen Preservation; Sensitivity and Specificity; Septal Nuclei; Sequence Analysis, DNA; Serum Albumin; Serum Albumin, Human; Shear Strength; Sodium Pertechnetate Tc 99m; Sodium-Hydrogen Exchangers; Soil Microbiology; SOXB1 Transcription Factors; Spain; Species Specificity; Sperm Motility; Spermatozoa; Spheroids, Cellular; Spores, Fungal; Stroke; Superoxide Dismutase; Swine; Tandem Mass Spectrometry; Technetium Compounds; Technetium Tc 99m Exametazime; Technetium Tc 99m Sestamibi; Temperature; Thiosulfates; Thrombosis; Thyroid Neoplasms; Transducers; Transfection; Transplantation, Heterologous; Treatment Outcome; Triazines; Tumor Burden; Urocortins; Uterine Cervical Neoplasms; Vacuoles; Valproic Acid; Ventral Tegmental Area; Vitamin K 2; Vitamin K Epoxide Reductases; Warfarin; Water Microbiology; Young Adult | 2016 |
162 other study(ies) available for pyrroles and antalarmin
| Article | Year |
|---|---|
In vivo and in vitro characterization of antalarmin, a nonpeptide corticotropin-releasing hormone (CRH) receptor antagonist: suppression of pituitary ACTH release and peripheral inflammation.
Topics: Adrenocorticotropic Hormone; Animals; Binding, Competitive; Carrageenan; Cerebellum; Corticotropin-Releasing Hormone; Frontal Lobe; Inflammation; Injections, Subcutaneous; Male; Myocardium; Pituitary Gland; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Sheep | 1996 |
Chronic effects of a nonpeptide corticotropin-releasing hormone type I receptor antagonist on pituitary-adrenal function, body weight, and metabolic regulation.
Topics: Adipose Tissue; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Apoptosis; Blotting, Northern; Body Weight; Corticosterone; Leptin; Male; Metabolism; Microscopy, Electron; Pituitary Gland; Proteins; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; RNA, Messenger | 1998 |
A corticotropin-releasing hormone type I receptor antagonist delays parturition in sheep.
Topics: Adrenocorticotropic Hormone; Animals; Female; Fetal Blood; Fetus; Hydrocortisone; Injections, Intravenous; Labor, Obstetric; Pharmaceutical Vehicles; Pregnancy; Pregnancy, Animal; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Sheep | 1998 |
The impact of the nonpeptide corticotropin-releasing hormone antagonist antalarmin on behavioral and endocrine responses to stress.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Animals; Behavior, Animal; Conditioning, Operant; Corticotropin-Releasing Hormone; Electroshock; Escape Reaction; Fear; Male; Pituitary-Adrenal System; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Stress, Physiological | 1999 |
Peripheral urocortin delays gastric emptying: role of CRF receptor 2.
Topics: Animals; Corticotropin-Releasing Hormone; Gastric Emptying; Humans; Injections, Intravenous; Intestinal Obstruction; Male; Peptide Fragments; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Recombinant Proteins; Urocortins | 1999 |
Chronic administration of the non-peptide CRH type 1 receptor antagonist antalarmin does not blunt hypothalamic-pituitary-adrenal axis responses to acute immobilization stress.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Hypothalamo-Hypophyseal System; Pituitary-Adrenal System; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Restraint, Physical; Stress, Physiological | 1999 |
Effects of corticotropin-releasing factor on neuronal activity in the serotonergic dorsal raphe nucleus.
Topics: Animals; Cerebral Ventricles; Corticotropin-Releasing Hormone; Immunohistochemistry; Infusions, Parenteral; Injections, Intraventricular; Male; Neurons; Pyrimidines; Pyrroles; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Serotonin | 2000 |
Effects of a novel corticotropin-releasing-hormone receptor type I antagonist on human adrenal function.
Topics: Adrenal Cortex; Adrenal Medulla; Adrenocorticotropic Hormone; Adult; Animals; Cell Line; Cells, Cultured; Chromaffin Cells; Coculture Techniques; Corticotropin-Releasing Hormone; Gene Expression Regulation; Haplorhini; Humans; Hydrocortisone; Pituitary Gland; Pyrimidines; Pyrroles; Rats; Receptors, Corticotropin-Releasing Hormone; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic | 2000 |
Oral administration of a corticotropin-releasing hormone receptor antagonist significantly attenuates behavioral, neuroendocrine, and autonomic responses to stress in primates.
Topics: Administration, Oral; Adrenocorticotropic Hormone; Animals; Anti-Anxiety Agents; Anxiety; Arginine Vasopressin; Corticotropin-Releasing Hormone; Double-Blind Method; Drug Evaluation, Preclinical; Epinephrine; Exploratory Behavior; Fear; Hydrocortisone; Hypothalamo-Hypophyseal System; Macaca mulatta; Male; Norepinephrine; Pituitary-Adrenal System; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Sexual Behavior, Animal; Social Dominance; Stress, Psychological | 2000 |
Antalarmin blockade of corticotropin releasing hormone-induced hypertension in rats.
Topics: Animals; Blood Pressure; Corticotropin-Releasing Hormone; Hypertension; Male; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone | 2000 |
Corticotropin-releasing hormone promotes blastocyst implantation and early maternal tolerance.
Topics: Animals; Apoptosis; Blastocyst; Cells, Cultured; Corticotropin-Releasing Hormone; Decidua; Embryo Implantation; Endometrium; Fas Ligand Protein; fas Receptor; Female; Gene Expression Regulation; Histocompatibility; Humans; Inflammation; Litter Size; Membrane Glycoproteins; Pregnancy; Pyrimidines; Pyrroles; Rats; Rats, Inbred F344; Rats, Nude; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; T-Lymphocyte Subsets; Trophoblasts | 2001 |
Corticotropin releasing hormone (CRH) antagonist attenuates adjuvant induced arthritis: role of CRH in peripheral inflammation.
Topics: Animals; Arthritis, Experimental; Corticotropin-Releasing Hormone; Disease Models, Animal; Female; Immunohistochemistry; Male; Multivariate Analysis; Probability; Pyrimidines; Pyrroles; Rats; Rats, Inbred F344; Rats, Inbred Lew; Receptors, Corticotropin-Releasing Hormone; Reference Values; Sensitivity and Specificity; Treatment Outcome | 2002 |
Marked suppression of gastric ulcerogenesis and intestinal responses to stress by a novel class of drugs.
Topics: Analysis of Variance; Animals; Bupropion; Buspirone; Colon; Corticotropin-Releasing Hormone; Diazepam; Dose-Response Relationship, Drug; Fluoxetine; Gastric Mucosa; Male; Mucins; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Stomach Ulcer | 2002 |
Effect of antalarmin, a novel corticotropin-releasing hormone antagonist, on the dynamic function of the preterm ovine fetal hypothalamo-pituitary-adrenal axis.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Corticotropin-Releasing Hormone; Cosyntropin; Female; Fetal Hypoxia; Gestational Age; Hydrocortisone; Hypothalamus; Kinetics; Oxygen; Pituitary Gland; Pregnancy; Pyrimidines; Pyrroles; Sheep | 2002 |
Corticotropin-releasing hormone antagonists possess anti-inflammatory effects in the mouse ileum.
Topics: Animals; Anti-Inflammatory Agents; Bacterial Toxins; Corticotropin-Releasing Hormone; Enteritis; Hormone Antagonists; Ileum; Male; Mice; Pyrimidines; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2002 |
Effects of antalarmin, a CRF type 1 receptor antagonist, on anxiety-like behavior and motor activation in the rat.
Topics: Animals; Anxiety; Corticotropin-Releasing Hormone; Humans; Male; Maze Learning; Motor Activity; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone | 2002 |
Corticotropin-releasing hormone augments proinflammatory cytokine production from macrophages in vitro and in lipopolysaccharide-induced endotoxin shock in mice.
Topics: Animals; Cell Line; Corticosterone; Corticotropin-Releasing Hormone; Cytokines; Hypothalamo-Hypophyseal System; Lethal Dose 50; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred BALB C; Pituitary-Adrenal System; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Shock, Septic | 2002 |
Antalarmin, a putative CRH-RI antagonist, has transient reinforcing effects in rhesus monkeys.
Topics: Adrenocorticotropic Hormone; Anesthetics, Intravenous; Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Hydrocortisone; Hypothalamo-Hypophyseal System; Macaca mulatta; Male; Methohexital; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Reinforcement, Psychology; Self Administration; Time Factors | 2002 |
Circuitry underlying regulation of the serotonergic system by swim stress.
Topics: Animals; Biomarkers; Cell Count; Corticotropin-Releasing Hormone; gamma-Aminobutyric Acid; Male; Neural Pathways; Neurons; Proto-Oncogene Proteins c-fos; Pyrimidines; Pyrroles; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Serotonin; Stress, Physiological; Swimming | 2003 |
The CRF1 receptor antagonist antalarmin reduces volitional ethanol consumption in isolation-reared fawn-hooded rats.
Topics: Alcohol Drinking; Animals; Pyrimidines; Pyrroles; Rats; Receptors, Corticotropin-Releasing Hormone; Social Isolation; Volition | 2003 |
Control by tachykinin NK(2) receptors of CRF(1) receptor-mediated activation of hippocampal acetylcholine release in the rat and guinea-pig.
Topics: Acetylcholine; Animals; Benzamides; Dose-Response Relationship, Drug; Guinea Pigs; Hippocampus; Injections, Intraventricular; Male; Microdialysis; Neurokinin-1 Receptor Antagonists; Physical Stimulation; Piperidines; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Receptors, Neurokinin-2; Species Specificity; Stereoisomerism; Tetrazoles | 2003 |
Effects of the selective nonpeptide corticotropin-releasing factor receptor 1 antagonist antalarmin in the chronic mild stress model of depression in mice.
Topics: Animals; Depression; Disease Models, Animal; Drug Therapy, Combination; Fluoxetine; Male; Mice; Mice, Inbred BALB C; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Selective Serotonin Reuptake Inhibitors; Stress, Psychological | 2003 |
Increased depression-like behaviors in corticotropin-releasing factor receptor-2-deficient mice: sexually dichotomous responses.
Topics: Animals; Behavior, Animal; Depression; Disease Models, Animal; Female; Male; Mice; Mice, Neurologic Mutants; Motor Activity; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Sex Factors; Stress, Physiological; Swimming | 2003 |
The effect of chronic CRF1 receptor blockade on the central CCK systems of Fawn-Hooded rats.
Topics: Animals; Brain; Cholecystokinin; Corticotropin-Releasing Hormone; Pyrimidines; Pyrroles; Rats; Receptors, Corticotropin-Releasing Hormone; RNA, Messenger | 2003 |
Selective activation of corticotropin-releasing factor-2 receptors on neurochemically identified neurons in the rat dorsal raphe nucleus reveals dual actions.
Topics: Animals; Area Under Curve; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Drug Administration Routes; Iontophoresis; Ligands; Male; Neural Inhibition; Neurons; Peptide Fragments; Pyrimidines; Pyrroles; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Serotonin; Urocortins | 2004 |
Corticotropin-releasing hormone antagonists, astressin B and antalarmin: differing profiles of activity in rhesus monkeys.
Topics: Adrenocorticotropic Hormone; Animals; Area Under Curve; Behavior, Animal; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Female; Hydrocortisone; Hypothalamo-Hypophyseal System; Macaca mulatta; Male; Motor Activity; Peptide Fragments; Pituitary-Adrenal System; Pyrimidines; Pyrroles | 2004 |
Ligand affinity for amino-terminal and juxtamembrane domains of the corticotropin releasing factor type I receptor: regulation by G-protein and nonpeptide antagonists.
Topics: Amphibian Proteins; Aniline Compounds; Animals; Binding, Competitive; Cell Line; Corticotropin-Releasing Hormone; Extracellular Space; GTP-Binding Proteins; Humans; Ligands; Models, Chemical; Peptide Fragments; Peptide Hormones; Peptides; Protein Binding; Protein Structure, Tertiary; Pyrazoles; Pyrimidines; Pyrroles; Rats; Receptors, Corticotropin-Releasing Hormone; Triazines; Urocortins | 2004 |
Corticotropin-releasing factor and urocortin differentially modulate rat Purkinje cell dendritic outgrowth and differentiation in vitro.
Topics: Analysis of Variance; Animals; Animals, Newborn; Calbindins; Carbazoles; Cell Count; Cell Differentiation; Corticotropin-Releasing Hormone; Dendrites; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Flavonoids; Hippocampus; Humans; Immunohistochemistry; In Vitro Techniques; Indoles; Linear Models; Neuroprotective Agents; Purkinje Cells; Pyrimidines; Pyrroles; Rats; S100 Calcium Binding Protein G; Time Factors; Urocortins | 2004 |
Buprenorphine and a CRF1 antagonist block the acquisition of opiate withdrawal-induced conditioned place aversion in rats.
Topics: Acamprosate; Analgesics, Opioid; Animals; Antidepressive Agents, Second-Generation; Avoidance Learning; Buprenorphine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Implants; Fluoxetine; Lisuride; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Substance Withdrawal Syndrome; Taurine | 2005 |
Corticotropin-releasing hormone stimulates NF-kappaB in human epidermal keratinocytes.
Topics: Adult; Blotting, Western; Calcium-Binding Proteins; Cell Nucleus; Cells, Cultured; Chloramphenicol O-Acetyltransferase; Corticotropin-Releasing Hormone; Cytoplasm; DNA; Electrophoretic Mobility Shift Assay; Gene Expression; Genes, Reporter; Humans; I-kappa B Proteins; Keratinocytes; Membrane Glycoproteins; Microscopy, Confocal; Nerve Tissue Proteins; NF-kappa B; Peptide Fragments; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Stimulation, Chemical; Synaptotagmin I; Synaptotagmins; Translocation, Genetic | 2004 |
Involvement of the neuropeptide corticotropin-releasing hormone in an animal model of Shigella-related seizures.
Topics: Animals; Corticotropin-Releasing Hormone; Disease Models, Animal; Male; Mice; Mice, Inbred ICR; Pentylenetetrazole; Pyrimidines; Pyrroles; Seizures; Shigella; Time Factors | 2004 |
Antidepressant-like activity of corticotropin-releasing factor type-1 receptor antagonists in mice.
Topics: Animals; Antidepressive Agents; Clorgyline; Desipramine; Dose-Response Relationship, Drug; Fluoxetine; Hindlimb Suspension; Male; Mice; Morpholines; Motor Activity; Paroxetine; Pyrazoles; Pyrimidines; Pyrroles; Reboxetine; Receptors, Corticotropin-Releasing Hormone; Selegiline; Swimming; Tranylcypromine; Triazines | 2004 |
Behavioral, adrenal, and sympathetic responses to long-term administration of an oral corticotropin-releasing hormone receptor antagonist in a primate stress paradigm.
Topics: Administration, Oral; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Behavior, Animal; Catecholamines; Corticotropin-Releasing Hormone; Hydrocortisone; Macaca mulatta; Male; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Stress Disorders, Traumatic; Sympathetic Nervous System | 2004 |
Reduced hypothalamic vasopressin secretion underlies attenuated adrenocorticotropin stress responses in pregnant rats.
Topics: Adrenocorticotropic Hormone; Animals; Dose-Response Relationship, Drug; Female; Hypothalamus; In Situ Hybridization; Pregnancy; Pregnancy, Animal; Pro-Opiomelanocortin; Pyrimidines; Pyrroles; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Receptors, Vasopressin; RNA, Messenger; Time Factors; Vasopressins | 2005 |
A CRH1 antagonist into the amygdala of mice prevents defeat-induced defensive behavior.
Topics: Aggression; Amygdala; Animals; Conflict, Psychological; Fear; Injections; Interpersonal Relations; Memory; Mice; Mice, Inbred C57BL; Motor Activity; Olfactory Bulb; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone | 2004 |
The effects of CRF antagonists, antalarmin, CP154,526, LWH234, and R121919, in the forced swim test and on swim-induced increases in adrenocorticotropin in rats.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Corticotropin-Releasing Hormone; Hypothalamo-Hypophyseal System; Male; Pituitary-Adrenal System; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Restraint, Physical; Stress, Psychological; Swimming; Triazoles | 2005 |
Quantitative determination of antalarmin, a novel corticotropin-releasing hormone receptor-1 antagonist, in canine plasma by HPLC-MS.
Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Mass Spectrometry; Molecular Structure; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone | 2005 |
Corticosterone implants to the amygdala and type 1 CRH receptor regulation: effects on behavior and colonic sensitivity.
Topics: Amygdala; Animals; Behavior, Animal; Colon; Corticosterone; Drug Delivery Systems; Drug Interactions; Male; Maze Learning; Muscle Contraction; Pempidine; Pyrimidines; Pyrroles; Radioimmunoassay; Rats; Rats, Inbred F344; Receptors, Corticotropin-Releasing Hormone; Stress, Psychological; Time Factors | 2005 |
Corticotropin-releasing factor 1 receptor-mediated mechanisms inhibit colonic hypersensitivity in rats.
Topics: Animals; Anxiety; Colon; Colonic Diseases; Corticotropin-Releasing Hormone; Hormone Antagonists; Irritable Bowel Syndrome; Physical Stimulation; Pyrimidines; Pyrroles; Rats; Rats, Inbred F344; Rats, Inbred WKY; Receptors, Corticotropin-Releasing Hormone; Reflex; Species Specificity | 2005 |
Peripheral injection of sauvagine prevents repeated colorectal distension-induced visceral pain in female rats.
Topics: Abdominal Pain; Amphibian Proteins; Animals; Colon; Dilatation, Pathologic; Female; Injections, Subcutaneous; Muscle Contraction; Peptide Hormones; Peptides; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Rectum | 2005 |
Chronic corticotropin-releasing factor type 1 receptor antagonism with antalarmin regulates the dopaminergic system of Fawn-Hooded rats.
Topics: Amygdala; Animals; Basal Ganglia; Brain; Corticotropin-Releasing Hormone; Dendritic Spines; Dopamine; Drug Administration Schedule; Male; Mesencephalon; Neural Pathways; Presynaptic Terminals; Pyrimidines; Pyrroles; Rats; Receptors, Corticotropin-Releasing Hormone; Receptors, Dopamine D1; Reinforcement, Psychology; Reward; RNA, Messenger; Synaptic Transmission; Tyrosine 3-Monooxygenase; Up-Regulation | 2005 |
Corticotropin-releasing hormone and urocortin induce secretion of matrix metalloproteinase-9 (MMP-9) without change in tissue inhibitors of MMP-1 by cultured cells from human placenta and fetal membranes.
Topics: Amnion; Cells, Cultured; Chorion; Corticotropin-Releasing Hormone; Extraembryonic Membranes; Humans; Matrix Metalloproteinase 9; Peptide Fragments; Placenta; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Trophoblasts; Urocortins | 2005 |
A centrally acting, anxiolytic angiotensin II AT1 receptor antagonist prevents the isolation stress-induced decrease in cortical CRF1 receptor and benzodiazepine binding.
Topics: Amphibian Proteins; Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Autoradiography; Behavior, Animal; Benzimidazoles; Benzodiazepines; Biphenyl Compounds; Cerebral Cortex; Disease Models, Animal; Flunitrazepam; GABA Modulators; In Situ Hybridization; Male; Maze Learning; Peptide Hormones; Peptides; Protein Binding; Pyrimidines; Pyrroles; Rats; Receptor, Angiotensin, Type 2; Receptors, Corticotropin-Releasing Hormone; RNA, Messenger; Social Isolation; Stress, Physiological; Tetrazoles; Tyrosine 3-Monooxygenase | 2006 |
The anxiogenic drug yohimbine reinstates palatable food seeking in a rat relapse model: a role of CRF1 receptors.
Topics: Adrenergic alpha-Antagonists; Animals; Anxiety; Behavior, Animal; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Extinction, Psychological; Food Preferences; Interpersonal Relations; Male; Pyrimidines; Pyrroles; Rats; Rats, Long-Evans; Receptors, Corticotropin-Releasing Hormone; Yohimbine | 2006 |
Impact of state of arousal and stress neuropeptides on urodynamic function in freely moving rats.
Topics: Animals; Arousal; Corticotropin-Releasing Hormone; Electroencephalography; Hormone Antagonists; Injections, Spinal; Male; Movement; Neuropeptides; Peptide Fragments; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Sleep; Urocortins; Urodynamics; Wakefulness | 2006 |
Facilitation of cardiac vagal activity by CRF-R1 antagonists during swim stress in rats.
Topics: Animals; Bradycardia; Cholinergic Antagonists; Corticotropin-Releasing Hormone; Death, Sudden, Cardiac; Disease Models, Animal; Exercise Tolerance; Fatigue; Heart Rate; Hypothalamo-Hypophyseal System; Hypothermia, Induced; Male; Mifepristone; Peptide Fragments; Psychomotor Agitation; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Stress, Psychological; Swimming; Vagus Nerve; Vagus Nerve Diseases | 2006 |
The CRF1 receptor antagonist, antalarmin, reverses isolation-induced up-regulation of dopamine D2 receptors in the amygdala and nucleus accumbens of fawn-hooded rats.
Topics: Amygdala; Animals; Behavior, Animal; Benzazepines; Brain-Derived Neurotrophic Factor; Dopamine Agonists; Dopamine Antagonists; Male; Nucleus Accumbens; Pyrimidines; Pyrroles; Rats; Rats, Inbred Strains; Receptor, trkB; Receptors, Corticotropin-Releasing Hormone; Receptors, Dopamine D1; Receptors, Dopamine D2; Salicylamides; Social Isolation; Up-Regulation | 2006 |
Glucocorticoid blockade reverses psychological stress-induced abnormalities in epidermal structure and function.
Topics: Animals; Dose-Response Relationship, Drug; Epidermis; Female; Glucocorticoids; Mice; Mice, Hairless; Mifepristone; Pyrimidines; Pyrroles; Skin Diseases; Stress, Psychological | 2006 |
Corticotropin-releasing factor 1 antagonists selectively reduce ethanol self-administration in ethanol-dependent rats.
Topics: Alcoholism; Animals; Behavior, Animal; Central Nervous System Depressants; Conditioning, Operant; Corticotropin-Releasing Hormone; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Hormone Antagonists; Male; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Self Administration; Triazines | 2007 |
Dissociation between opioid and CRF1 antagonist sensitive drinking in Sardinian alcohol-preferring rats.
Topics: Alcohol Drinking; Animals; Behavior, Addictive; Central Nervous System Agents; Drinking; Ethanol; Male; Naltrexone; Narcotic Antagonists; Pyrimidines; Pyrroles; Rats; Rats, Inbred Strains; Receptors, Corticotropin-Releasing Hormone; Reinforcement, Psychology; Self Administration; Stress, Psychological; Triazines | 2006 |
Evidence that corticotropin-releasing factor receptor type 1 couples to Gs- and Gi-proteins through different conformations of its J-domain.
Topics: Allosteric Regulation; Amphibian Proteins; Binding, Competitive; Cell Line; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Hormone Antagonists; Humans; Models, Molecular; Peptide Fragments; Peptide Hormones; Peptides; Protein Conformation; Protein Structure, Tertiary; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Signal Transduction; Transfection; Urocortins | 2006 |
Evidence that corticotropin-releasing hormone inhibits cell growth of human breast cancer cells via the activation of CRH-R1 receptor subtype.
Topics: Autocrine Communication; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Estradiol; Female; Hormones; Humans; Paracrine Communication; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone | 2007 |
Effects of the CRF1 antagonist antalarmin on cocaine self-administration and discrimination in rhesus monkeys.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Corticotropin-Releasing Hormone; Discrimination, Psychological; Female; Hypothalamo-Hypophyseal System; Macaca mulatta; Male; Pituitary-Adrenal System; Pyrimidines; Pyrroles; Self Administration | 2006 |
Corticotropin-releasing hormone skin signaling is receptor-mediated and is predominant in the sebaceous glands.
Topics: Amphibian Proteins; Carrier Proteins; Cell Proliferation; Cell Survival; Corticotropin-Releasing Hormone; Interleukin-1; Interleukin-6; Interleukin-8; Peptide Hormones; Peptides; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Sebaceous Glands; Signal Transduction; Skin; Skin Physiological Phenomena; Urocortins; Urotensins | 2007 |
Mechanisms involved in the anti-inflammatory action of inhaled tea tree oil in mice.
Topics: Administration, Inhalation; Animals; Anti-Inflammatory Agents; Cell Count; Cyclooxygenase Inhibitors; Hypothalamo-Hypophyseal System; Immunologic Factors; Leukocytes; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Models, Biological; Peritoneal Cavity; Pituitary-Adrenal System; Prostaglandin-Endoperoxide Synthases; Pyrimidines; Pyrroles; Reactive Oxygen Species; Receptors, Corticotropin-Releasing Hormone; Tea Tree Oil; Tetradecanoylphorbol Acetate; Thiophenes; Zymosan | 2007 |
Alleviation of the effects of endotoxin exposure on behavior and hippocampal IL-1beta by a selective non-peptide antagonist of corticotropin-releasing factor receptors.
Topics: Analysis of Variance; Animals; Association Learning; Avoidance Learning; Corticotropin-Releasing Hormone; Hippocampus; Hormone Antagonists; Interleukin-1beta; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Statistics, Nonparametric | 2007 |
Treatment with CRH-1 antagonist antalarmin reduces behavioral and endocrine responses to social stressors in marmosets (Callithrix kuhlii).
Topics: Animals; Behavior, Animal; Callithrix; Female; Hydrocortisone; Male; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Sexual Behavior, Animal; Social Behavior; Social Isolation; Stress, Psychological | 2007 |
Dependence-induced increases in ethanol self-administration in mice are blocked by the CRF1 receptor antagonist antalarmin and by CRF1 receptor knockout.
Topics: Alcoholism; Animals; Conditioning, Operant; Ethanol; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Self Administration | 2007 |
Corticotropin-releasing factor receptors differentially regulate stress-induced tau phosphorylation.
Topics: Adrenalectomy; Analysis of Variance; Animals; Antibodies, Monoclonal; Corticosterone; Corticotropin-Releasing Hormone; Gene Expression Regulation; Immunoprecipitation; Injections, Intraventricular; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; Protein Kinases; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Stress, Physiological; tau Proteins; Time Factors | 2007 |
Neonatal gastric suctioning results in chronic visceral and somatic hyperalgesia: role of corticotropin releasing factor.
Topics: Abdominal Pain; Animals; Animals, Newborn; Catheterization; Chronic Disease; Corticotropin-Releasing Hormone; Gastric Mucosa; Hot Temperature; Hyperalgesia; Intubation, Gastrointestinal; Male; Manometry; Nociceptors; Pyrimidines; Pyrroles; Rats; Rats, Long-Evans; Receptors, Corticotropin-Releasing Hormone; Suction | 2007 |
The CRF1 receptor antagonist antalarmin attenuates yohimbine-induced increases in operant alcohol self-administration and reinstatement of alcohol seeking in rats.
Topics: Adrenergic alpha-Antagonists; Alcoholism; Animals; Behavior, Addictive; Conditioning, Operant; Dose-Response Relationship, Drug; Ethanol; Male; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Self Administration; Yohimbine | 2007 |
Urocortin I is present in the enteric nervous system and exerts an excitatory effect via cholinergic and serotonergic pathways in the rat colon.
Topics: Animals; Atropine; Colon; Corticotropin-Releasing Hormone; Dioxanes; Electric Stimulation; Enteric Nervous System; Gastrointestinal Motility; Hexamethonium; Immunohistochemistry; Male; NG-Nitroarginine Methyl Ester; Ondansetron; Peptide Fragments; Piperidines; Pyrimidines; Pyrroles; Rats; Receptors, Corticotropin-Releasing Hormone; Serotonin 5-HT3 Receptor Antagonists; Serotonin 5-HT4 Receptor Antagonists; Tetrodotoxin; Urocortins | 2007 |
Corticotropin-releasing factor 1 and 2 receptors in the dorsal raphé differentially affect serotonin release in the nucleus accumbens.
Topics: Animals; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Humans; Male; Microdialysis; Nucleus Accumbens; Peptide Fragments; Pyrimidines; Pyrroles; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Serotonin; Time Factors | 2008 |
Stress-induced intracellular trafficking of corticotropin-releasing factor receptors in rat locus coeruleus neurons.
Topics: Animals; Cell Compartmentation; Corticotropin-Releasing Hormone; Hormone Antagonists; Locus Coeruleus; Male; Neurons; Protein Transport; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Stress, Physiological; Swimming; Tissue Distribution | 2008 |
CRF(1) receptor antagonists attenuate escalated cocaine self-administration in rats.
Topics: Animals; Behavior, Addictive; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Self Administration; Time Factors | 2008 |
Integration of in vivo and in vitro approaches to characterize the toxicity of Antalarmin, a corticotropin-releasing hormone receptor antagonist.
Topics: Animals; Bone Marrow Cells; Cell Line, Tumor; Colony-Forming Units Assay; Dogs; Female; Humans; Kidney; Liver; Male; Mice; Mutagenicity Tests; No-Observed-Adverse-Effect Level; Pyrimidines; Pyrroles; Rats; Rats, Inbred F344; Receptors, Corticotropin-Releasing Hormone; Salmonella typhimurium; Vomiting | 2008 |
Preformulation and pharmacokinetic studies on antalarmin: a novel stress inhibitor.
Topics: Animals; Chemistry, Pharmaceutical; Male; Pyrimidines; Pyrroles; Rats; Rats, Inbred F344; Receptors, Corticotropin-Releasing Hormone; Solubility; Stress, Physiological | 2009 |
Footshock-induced urinary bladder hypersensitivity: role of spinal corticotropin-releasing factor receptors.
Topics: Animals; Corticotropin-Releasing Hormone; Electromyography; Electroshock; Female; Foot; Injections, Spinal; Peptide Fragments; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Spinal Cord; Stress, Psychological; Urinary Bladder; Urinary Bladder, Overactive; Urocortins; Urodynamics | 2008 |
Corticotropin-releasing factor in the dorsal raphe nucleus increases medial prefrontal cortical serotonin via type 2 receptors and median raphe nucleus activity.
Topics: Amygdala; Animals; Corticotropin-Releasing Hormone; Electric Stimulation; Male; Microdialysis; Peptide Fragments; Prefrontal Cortex; Pyrimidines; Pyrroles; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Serotonin | 2008 |
Mechanisms of withdrawal-associated increases in heroin self-administration: pharmacologic modulation of heroin vs food choice in heroin-dependent rhesus monkeys.
Topics: Adrenergic Agents; Adrenergic Agonists; Amphetamine; Animals; Behavior, Addictive; Choice Behavior; Clonidine; Dopamine Agents; Dose-Response Relationship, Drug; Food; Heroin; Heroin Dependence; Macaca mulatta; Male; Morphine; Narcotic Antagonists; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Self Administration; Substance Withdrawal Syndrome | 2009 |
Involvement of CRH receptors in urocortin-induced hyperthermia.
Topics: Animals; Body Temperature; Colon; Corticotropin-Releasing Hormone; Hyperthermia, Induced; Injections, Intraventricular; Male; Peptide Fragments; Peptides, Cyclic; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Urocortins | 2008 |
Effects of antalarmin, a CRF receptor 1 antagonist, on fright reaction and endocrine stress response in crucian carp (Carassius carassius).
Topics: Animals; Behavior, Animal; Carps; Fear; Hydrocortisone; Motor Activity; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Smell; Stereotyped Behavior; Stress, Physiological | 2008 |
Antagonism of specific corticotropin-releasing factor receptor subtypes selectively modifies weight loss in restrained rats.
Topics: Animals; Corticosterone; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Eating; Feeding Behavior; Infusions, Parenteral; Injections, Subcutaneous; Male; Peptide Fragments; Prosencephalon; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Restraint, Physical; Stress, Psychological; Time Factors; Weight Loss | 2008 |
Corticotropin releasing factor enhances attentional function as assessed by the five-choice serial reaction time task in rats.
Topics: Animals; Appetite; Attention; Choice Behavior; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Hormones; Impulsive Behavior; Injections, Intraventricular; Male; Motivation; Motor Activity; Neuropsychological Tests; Psychomotor Performance; Pyrimidines; Pyrroles; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Corticotropin-Releasing Hormone; Serial Learning | 2009 |
Endocrine, behavioral and autonomic effects of neuropeptide AF.
Topics: Adrenocorticotropic Hormone; Animals; Anti-Anxiety Agents; Behavior, Animal; Body Temperature; Brain; Central Nervous System Agents; Corticosterone; Diazepam; Dopamine; Dopamine Antagonists; Haloperidol; Heart Rate; Hypothalamo-Hypophyseal System; In Vitro Techniques; Male; Motor Activity; Oligopeptides; Peptide Fragments; Peptides, Cyclic; Pituitary-Adrenal System; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone | 2009 |
Activation of corticotropin-releasing factor receptor 2 in lateral septum negatively regulates maternal defense.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Female; Maternal Behavior; Mice; Mice, Inbred ICR; Proto-Oncogene Proteins c-fos; Pyrimidines; Pyrroles; Reaction Time; Receptors, Corticotropin-Releasing Hormone; Septum of Brain; Urocortins | 2009 |
Neuropeptide S reinstates cocaine-seeking behavior and increases locomotor activity through corticotropin-releasing factor receptor 1 in mice.
Topics: Analysis of Variance; Animals; Anxiety; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Extinction, Psychological; Injections, Intraventricular; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neuropeptides; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Self Administration | 2009 |
Nicotine suppresses energy storage through activation of sympathetic outflow to brown adipose tissue via corticotropin-releasing factor type 1 receptor.
Topics: Adipose Tissue, Brown; Animals; Energy Metabolism; Injections, Intraperitoneal; Male; Nicotine; Norepinephrine; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Sympathetic Nervous System | 2009 |
Swim stress excitation of nucleus incertus and rapid induction of relaxin-3 expression via CRF1 activation.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Gene Expression Regulation; Male; Nerve Tissue Proteins; Neurons; Paraventricular Hypothalamic Nucleus; Pons; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Relaxin; RNA, Messenger; Stress, Psychological; Swimming; Time Factors | 2010 |
Effects of antalarmin and nadolol on the relationship between social stress and pulmonary metastasis development in male OF1 mice.
Topics: Adrenergic beta-Antagonists; Aggression; Animals; Central Nervous System Agents; Corticosterone; Interferon-gamma; Lung; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Nadolol; Neoplasms, Experimental; Pyrimidines; Pyrroles; Random Allocation; Receptors, Corticotropin-Releasing Hormone; Social Behavior; Stress, Psychological | 2009 |
Stress-induced potentiation of cocaine reward: a role for CRF R1 and CREB.
Topics: Animals; Cocaine; Conditioning, Classical; Cyclic AMP Response Element-Binding Protein; Dopamine Uptake Inhibitors; Mice; Mice, Knockout; Nucleus Accumbens; Phosphorylation; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Reward; Septum of Brain; Space Perception; Stress, Psychological; Swimming; Time Factors | 2009 |
Hypocretins regulate the anxiogenic-like effects of nicotine and induce reinstatement of nicotine-seeking behavior.
Topics: Animals; Anxiety; Arginine Vasopressin; Behavior, Addictive; Benzoxazoles; Conditioning, Operant; Corticotropin-Releasing Hormone; Extinction, Psychological; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Naphthyridines; Neurons; Neuropeptides; Nicotine; Orexin Receptors; Orexins; Paraventricular Hypothalamic Nucleus; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Self Administration; Tobacco Use Disorder; Urea | 2010 |
Involvement of microglial cells in infrasonic noise-induced stress via upregulated expression of corticotrophin releasing hormone type 1 receptor.
Topics: Acoustic Stimulation; Acoustics; Animals; Cells, Cultured; Gliosis; Hypothalamus; Immunohistochemistry; Male; Microglia; Noise; Paraventricular Hypothalamic Nucleus; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Reverse Transcriptase Polymerase Chain Reaction; Stress, Physiological; Up-Regulation | 2010 |
A specific CRH antagonist attenuates ACTH-stimulated cortisol secretion in ovine adrenocortical cells.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Cells, Cultured; Corticotropin-Releasing Hormone; Female; Hydrocortisone; Peptide Fragments; Pregnancy; Pyrimidines; Pyrroles; Sheep | 2010 |
Reversal by quercetin of corticotrophin releasing factor induced anxiety- and depression-like effect in mice.
Topics: Analysis of Variance; Animals; Antioxidants; Anxiety; Behavior, Animal; Corticotropin-Releasing Hormone; Depression; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Mice; Motor Activity; Pyrimidines; Pyrroles; Quercetin; Receptors, Corticotropin-Releasing Hormone; Social Behavior; Stress, Psychological; Swimming | 2010 |
Regulation of blood L-glutamate levels by stress as a possible brain defense mechanism.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adrenocorticotropic Hormone; Animals; Corticotropin-Releasing Hormone; Epinephrine; Glutamic Acid; Head Injuries, Closed; Hypothalamo-Hypophyseal System; Isoproterenol; Male; Pituitary-Adrenal System; Propranolol; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Corticotropin-Releasing Hormone; Stress, Physiological | 2010 |
Effect of CRH on NO bioavailability, ROS production and antioxidant defense systems in endothelial EAhy926 cells.
Topics: Antioxidants; Catalase; Cell Line; Corticotropin-Releasing Hormone; Culture Media, Conditioned; Endothelial Cells; Glutathione; Humans; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Peptide Fragments; Peptides, Cyclic; Pyrimidines; Pyrroles; Reactive Oxygen Species; Receptors, Corticotropin-Releasing Hormone; Superoxide Dismutase; Tyrosine | 2010 |
Exploring the binding site crevice of a family B G protein-coupled receptor, the type 1 corticotropin releasing factor receptor.
Topics: Amphibian Proteins; Binding Sites; Binding, Competitive; Cell Line; Cell Membrane; Ethyl Methanesulfonate; Humans; Ligands; Mutagenesis, Site-Directed; Peptide Hormones; Protein Binding; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Receptors, G-Protein-Coupled | 2010 |
Treatment with a CRH-R1 antagonist prevents stress-induced suppression of the central neural drive to the reproductive axis in female macaques.
Topics: Animals; Anovulation; Anti-Anxiety Agents; Central Nervous System; Circadian Rhythm; Diet; Female; Hydrocortisone; Infertility, Female; Injections, Intravenous; Luteinizing Hormone; Macaca fascicularis; Pyrimidines; Pyrroles; Random Allocation; Receptors, Corticotropin-Releasing Hormone; Social Environment; Stress, Psychological | 2011 |
The impact of stress on tumor growth: peripheral CRF mediates tumor-promoting effects of stress.
Topics: Animals; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Corticotropin-Releasing Hormone; Female; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Mice; Mice, Inbred BALB C; Pyrimidines; Pyrroles; Radioimmunoassay; Reverse Transcriptase Polymerase Chain Reaction; Stress, Physiological | 2010 |
CRF and urotensin I effects on aggression and anxiety-like behavior in rainbow trout.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aggression; Animals; Anxiety; Behavior, Animal; Corticotropin-Releasing Hormone; Dopamine; Hydrocortisone; Hydroxyindoleacetic Acid; Oncorhynchus mykiss; Peptide Fragments; Pyrimidines; Pyrroles; Rats; Serotonin; Social Dominance; Urotensins | 2011 |
Anxiety states induced by post-weaning social isolation are mediated by CRF receptors in the dorsal raphe nucleus.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Anxiety; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Maze Learning; Peptide Fragments; Pyrimidines; Pyrroles; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Social Isolation | 2011 |
Transient gastric irritation in the neonatal rats leads to changes in hypothalamic CRF expression, depression- and anxiety-like behavior as adults.
Topics: Animals; Animals, Newborn; Anxiety; Behavior, Animal; Corticotropin-Releasing Hormone; Depression; Dyspepsia; Hypothalamus; Male; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley | 2011 |
Effects of acute ethanol on corticotropin-releasing hormone and β-endorphin systems at the level of the rat central amygdala.
Topics: Amygdala; Animals; Behavior, Animal; beta-Endorphin; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Ethanol; Injections, Intraperitoneal; Male; Microdialysis; Microinjections; Peptide Fragments; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone | 2011 |
Involvement of CRF2 receptor in the brain regions in restraint-induced anorexia.
Topics: Animals; Anorexia; Disease Models, Animal; Dose-Response Relationship, Drug; Feeding Behavior; Male; Microinjections; Peptide Fragments; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Restraint, Physical; Septal Nuclei; Septum of Brain | 2011 |
Augmented cocaine seeking in response to stress or CRF delivered into the ventral tegmental area following long-access self-administration is mediated by CRF receptor type 1 but not CRF receptor type 2.
Topics: Aminopyridines; Analysis of Variance; Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Conditioning, Operant; Corticotropin-Releasing Hormone; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Extinction, Psychological; Flavonoids; Food Preferences; Glucosides; Male; Peptide Fragments; Peptides, Cyclic; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Reinforcement, Psychology; Self Administration; Stress, Psychological; Ventral Tegmental Area | 2011 |
Effects of corticotropin-releasing hormone receptor antagonists on the ethanol-induced increase of dynorphin A1-8 release in the rat central amygdala.
Topics: Amphibian Proteins; Amygdala; Animals; Corticotropin-Releasing Hormone; Dynorphins; Ethanol; Male; Microdialysis; Microinjections; Peptide Fragments; Peptide Hormones; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone | 2011 |
Corticotropin-releasing factor (CRF) receptor subtypes in mediating neuronal activation of brain areas involved in responses to intracerebroventricular CRF and stress in rats.
Topics: Amygdala; Animals; Immunohistochemistry; Infusions, Intraventricular; Male; Neurons; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Proto-Oncogene Proteins c-fos; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Restraint, Physical; Signal Transduction; Stress, Physiological; Time Factors | 2011 |
Urocortin 1 inhibits guinea pig gallbladder contractility in vitro via corticotropin-releasing factor receptor 2.
Topics: Acetylcholine; Animals; DNA, Complementary; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Gallbladder; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Muscles; Peptide Fragments; Peptides, Cyclic; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Signal Transduction; Urocortins | 2011 |
Pharmacological blockade of corticotropin-releasing hormone receptor 1 (CRH1R) reduces voluntary consumption of high alcohol concentrations in non-dependent Wistar rats.
Topics: Alcohol Deterrents; Alcohol Drinking; Alcoholic Intoxication; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drinking; Ethanol; Male; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Secondary Prevention; Stress, Psychological; Time Factors | 2012 |
Antagonizing corticotropin-releasing factor in the central nucleus of the amygdala attenuates fear-induced reductions in sleep but not freezing.
Topics: Amygdala; Animals; Corticotropin-Releasing Hormone; Electrodes, Implanted; Electroencephalography; Electromyography; Fear; Freezing Reaction, Cataleptic; Male; Proto-Oncogene Proteins c-fos; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Sleep; Sleep, REM | 2011 |
Lead diversification. Application to existing drug molecules: mifepristone 1 and antalarmin 8.
Topics: Biomimetics; Carbon; Chemistry, Pharmaceutical; Chlorine; Drug Design; Humans; Hydrogen; Inhibitory Concentration 50; Metalloporphyrins; Metals; Microsomes, Liver; Mifepristone; Models, Chemical; Oxygen; Pyrimidines; Pyrroles; Structure-Activity Relationship | 2012 |
Differential regulation of gonadotropin-releasing hormone by corticotropin-releasing factor family peptides in hypothalamic N39 cells.
Topics: Animals; Cell Line; Corticotropin-Releasing Hormone; Gene Expression Regulation; Gonadotropin-Releasing Hormone; Hypothalamus; Mice; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Receptors, Neuropeptide; Urocortins | 2012 |
Nicotine stimulates secretion of corticosterone via both CRH and AVP receptors.
Topics: Analysis of Variance; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Corticosterone; Corticotropin-Releasing Hormone; Drug Interactions; Indoles; Male; Mice; Mice, Inbred C57BL; Nicotine; Nicotinic Agonists; Peptide Fragments; Pyrimidines; Pyrroles; Pyrrolidines; Receptors, Corticotropin-Releasing Hormone; Receptors, Vasopressin | 2012 |
Differential regulation of glucose transporters mediated by CRH receptor type 1 and type 2 in human placental trophoblasts.
Topics: Corticotropin-Releasing Hormone; Female; Gene Expression Regulation, Developmental; Glucose Transport Proteins, Facilitative; Glucose Transporter Type 1; Glucose Transporter Type 3; Humans; Models, Biological; Peptide Fragments; Placenta; Pregnancy; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; RNA Interference; Trophoblasts | 2012 |
Corticotropin-releasing factor modulation of forebrain GABAergic transmission has a pivotal role in the expression of anabolic steroid-induced anxiety in the female mouse.
Topics: Acoustic Stimulation; Action Potentials; Amygdala; Analysis of Variance; Androgens; Animals; Anxiety; Corticotropin-Releasing Hormone; Disease Models, Animal; Dose-Response Relationship, Drug; Female; GABAergic Neurons; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Injections, Intraventricular; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Prosencephalon; Proto-Oncogene Proteins c-fos; Pyrimidines; Pyrroles; RNA, Messenger; Sensory Gating; Time Factors | 2012 |
Corticotropin-releasing factor receptor-dependent effects of repeated stress on tau phosphorylation, solubility, and aggregation.
Topics: Animals; Blotting, Western; Dentate Gyrus; Detergents; Female; Fluorescent Antibody Technique; Green Fluorescent Proteins; Hippocampus; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Microscopy, Immunoelectron; Neurons; Phosphorylation; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Solubility; Stress, Psychological; tau Proteins | 2012 |
Corticotropin-releasing hormone stimulates mitotic kinesin-like protein 1 expression via a PLC/PKC-dependent signaling pathway in hippocampal neurons.
Topics: Animals; Carbazoles; Cells, Cultured; Corticotropin-Releasing Hormone; Estrenes; GTP-Binding Protein alpha Subunits, Gs; Hippocampus; Kinesins; Microtubule-Associated Proteins; Neurons; Peptide Fragments; Protein Kinase C; Pyrimidines; Pyrroles; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Signal Transduction; Transcription, Genetic; Transcriptional Activation; Type C Phospholipases | 2012 |
Differential effects of acute morphine, and chronic morphine-withdrawal on obsessive-compulsive behavior: inhibitory influence of CRF receptor antagonists on chronic morphine-withdrawal.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice; Morphine; Motor Activity; Narcotics; Obsessive-Compulsive Disorder; Peptide Fragments; Peptides, Cyclic; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Substance Withdrawal Syndrome | 2012 |
Regulation of estradiol and progesterone production by CRH-R1 and -R2 is through divergent signaling pathways in cultured human placental trophoblasts.
Topics: Adult; Benzophenanthridines; Cells, Cultured; Enzyme Inhibitors; Estradiol; Estrenes; Female; Humans; Peptide Fragments; Peptides, Cyclic; Placenta; Pregnancy; Progesterone; Protein Kinase C; Pyrimidines; Pyrroles; Pyrrolidinones; Receptors, Corticotropin-Releasing Hormone; Signal Transduction; Trophoblasts | 2012 |
Divergent roles of the CRH receptors in the control of gonadotropin secretion induced by acute restraint stress at proestrus.
Topics: Animals; Corticotropin-Releasing Hormone; Female; Follicle Stimulating Hormone; Locus Coeruleus; Luteinizing Hormone; Neurons; Peptide Fragments; Peptides, Cyclic; Proestrus; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Restraint, Physical; Stress, Physiological; Tyrosine 3-Monooxygenase | 2012 |
Neuroprotection afforded by adenosine A2A receptor blockade is modulated by corticotrophin-releasing factor (CRF) in glutamate injured cortical neurons.
Topics: Adenosine A2 Receptor Antagonists; Animals; Cerebral Cortex; Corticotropin-Releasing Hormone; Glutamic Acid; Neural Inhibition; Neurons; Neuroprotective Agents; Primary Cell Culture; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Triazoles | 2012 |
Effects of corticotropin-releasing factor on intermediolateral cell column neurons of newborn rats.
Topics: Animals; Animals, Newborn; Biophysical Phenomena; Corticotropin-Releasing Hormone; Electric Stimulation; Excitatory Postsynaptic Potentials; In Vitro Techniques; Menthol; Neurons; Patch-Clamp Techniques; Pyrimidines; Pyrroles; Rats; Receptors, Corticotropin-Releasing Hormone; Spinal Cord | 2012 |
Upregulation of PVN CRHR1 by gestational intermittent hypoxia selectively triggers a male-specific anxiogenic effect in rat offspring.
Topics: Animals; Anxiety; Behavior, Animal; Female; Hypoxia; Male; Paraventricular Hypothalamic Nucleus; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Sex Factors | 2013 |
The effect of CRH and its inhibitor, antalarmin, on in vitro growth of preantral mouse follicles, early embryo development, and steroidogenesis.
Topics: Animals; Chorionic Gonadotropin, beta Subunit, Human; Corticotropin-Releasing Hormone; Embryonic Development; Estradiol; Female; Male; Mice; Ovarian Follicle; Pregnancy; Progesterone; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Reverse Transcriptase Polymerase Chain Reaction | 2013 |
Corticotropin-releasing hormone exerts direct effects on neuronal progenitor cells: implications for neuroprotection.
Topics: Animals; Apoptosis; Brain; Cell Proliferation; Corticotropin-Releasing Hormone; Dexamethasone; Humans; Mice; Mice, Knockout; Neurogenesis; Neuroprotective Agents; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Signal Transduction; Stem Cells | 2013 |
Basolateral amygdala and the regulation of fear-conditioned changes in sleep: role of corticotropin-releasing factor.
Topics: Amygdala; Animals; Behavior, Animal; Conditioning, Psychological; Corticotropin-Releasing Hormone; Electroencephalography; Electromyography; Electroshock; Fear; Habituation, Psychophysiologic; Memory; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Sleep; Sleep, REM | 2013 |
An intrinsic CRF signaling system within the optic tectum.
Topics: Animals; Anura; Appetite; Eating; Pyrimidines; Pyrroles; Real-Time Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Superior Colliculi; Xenopus laevis | 2013 |
Coping with chronic social stress in mice: hypothalamic-pituitary-adrenal/ sympathetic-adrenal-medullary axis activity, behavioral changes and effects of antalarmin treatment: implications for the study of stress-related psychopathologies.
Topics: Adaptation, Psychological; Adrenal Medulla; Animals; Hypothalamo-Hypophyseal System; Interpersonal Relations; Male; Mice; Pituitary-Adrenal System; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Stress, Psychological | 2013 |
CRF type 2 receptors mediate the metabolic effects of ghrelin in C2C12 cells.
Topics: Animals; Antibodies, Blocking; Biological Transport; Cell Line; Cell Membrane; Gene Expression Regulation; Ghrelin; Glucose; Glucose Transporter Type 4; Ion Channels; Mice; Mitochondrial Proteins; Myoblasts; Protein Transport; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Receptors, Ghrelin; Retinol-Binding Proteins, Plasma; Signal Transduction; Uncoupling Protein 2; Uncoupling Protein 3; Urocortins | 2014 |
Involvements of stress hormones in the restraint-induced conditioned place preference.
Topics: Animals; Association Learning; Conditioning, Operant; Corticosterone; Male; Mifepristone; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Stress, Physiological | 2013 |
Evidence of lasting dysregulation of neuroendocrine and HPA axis function following global cerebral ischemia in male rats and the effect of Antalarmin on plasma corticosterone level.
Topics: Animals; Behavior, Animal; Brain Ischemia; CA1 Region, Hippocampal; Central Amygdaloid Nucleus; Corticosterone; Corticotropin-Releasing Hormone; Hypothalamo-Hypophyseal System; Limbic System; Locus Coeruleus; Male; Memory, Short-Term; Neurosecretory Systems; Paraventricular Hypothalamic Nucleus; Pituitary-Adrenal System; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Receptors, Glucocorticoid; Stress, Psychological; Time Factors; Tyrosine 3-Monooxygenase | 2014 |
CRF type 1 receptors of the medial amygdala modulate inhibitory avoidance responses in the elevated T-maze.
Topics: Animals; Avoidance Learning; Behavior, Animal; Corticomedial Nuclear Complex; Corticotropin-Releasing Hormone; Inhibition, Psychological; Male; Maze Learning; Motor Activity; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone | 2014 |
Blocking of corticotrophin releasing factor receptor-1 during footshock attenuates context fear but not the upregulation of prepro-orexin mRNA in rats.
Topics: Animals; Behavior, Animal; Electroshock; Fear; Intracellular Signaling Peptides and Proteins; Male; Motor Activity; Neuropeptides; Orexins; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; RNA, Messenger; Up-Regulation; Vocalization, Animal | 2014 |
Beta-2 adrenergic receptors mediate stress-evoked reinstatement of cocaine-induced conditioned place preference and increases in CRF mRNA in the bed nucleus of the stria terminalis in mice.
Topics: Adrenergic beta-Agonists; Animals; Behavior, Addictive; Clenbuterol; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corticotropin-Releasing Hormone; Dopamine Uptake Inhibitors; Extinction, Psychological; Male; Mice; Pyrimidines; Pyrroles; Receptors, Adrenergic, beta-2; Receptors, Corticotropin-Releasing Hormone; Recurrence; Reward; Self Administration; Septal Nuclei; Stress, Psychological | 2014 |
Corticotropin-releasing hormone receptors mediate apoptosis via cytosolic calcium-dependent phospholipase A₂ and migration in prostate cancer cell RM-1.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; Cell Movement; Corticotropin-Releasing Hormone; Dactinomycin; Down-Regulation; HEK293 Cells; Humans; Interleukin-1beta; Male; Mice; Mitomycin; Peptide Fragments; Phospholipases A2; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; RNA Interference; RNA, Messenger; RNA, Small Interfering; Thapsigargin; Tumor Necrosis Factor-alpha; Up-Regulation; Urocortins | 2014 |
Urocortin 3 administration impairs fear motivated learning in mice is mediated by transmitters.
Topics: Adrenergic alpha-Antagonists; Animals; Arginine; Atropine; Avoidance Learning; Bicuculline; Corticotropin-Releasing Hormone; Dopamine Antagonists; Fear; GABA-A Receptor Antagonists; Haloperidol; Male; Memory; Mice; Mice, Inbred Strains; Motivation; Muscarinic Antagonists; Peptide Fragments; Phenoxybenzamine; Pyrimidines; Pyrroles; Urocortins | 2014 |
Structural-functional analysis of the third transmembrane domain of the corticotropin-releasing factor type 1 receptor: role in activation and allosteric antagonism.
Topics: Allosteric Regulation; Amino Acid Sequence; Cell Membrane; Conserved Sequence; HEK293 Cells; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Sequence Alignment; Structure-Activity Relationship | 2014 |
Effects of corticotrophin-releasing factor receptor 1 antagonists on amyloid-β and behavior in Tg2576 mice.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Corticotropin-Releasing Hormone; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Hippocampus; Male; Memory; Mice; Mice, Transgenic; Neurons; Plaque, Amyloid; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Signal Transduction | 2014 |
Dorsomedial hypothalamus CRF type 1 receptors selectively modulate inhibitory avoidance responses in the elevated T-maze.
Topics: Animals; Anxiety; Avoidance Learning; Corticotropin-Releasing Hormone; Escape Reaction; Hypothalamus; Male; Maze Learning; Motor Activity; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone | 2014 |
The role of kappa opioid receptors in stress-induced reinstatement of alcohol seeking in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Behavior, Addictive; Behavior, Animal; Cues; Drug-Seeking Behavior; Ethanol; Male; Naltrexone; Narcotic Antagonists; Pyrimidines; Pyrroles; Rats; Rats, Long-Evans; Receptors, Corticotropin-Releasing Hormone; Receptors, Opioid, kappa; Self Administration; Stress, Physiological; Yohimbine | 2014 |
Effects of dorsal periaqueductal gray CRF1- and CRF2-receptor stimulation in animal models of panic.
Topics: Animals; Anxiety; Behavior, Animal; Corticotropin-Releasing Hormone; Disease Models, Animal; Male; Microinjections; Panic; Periaqueductal Gray; Pyrimidines; Pyrroles; Rats; Receptors, Corticotropin-Releasing Hormone; Urocortins | 2014 |
Polymorphism in the corticotropin-releasing factor receptor 1 (CRF1-R) gene plays a role in shaping the high anxious phenotype of Marchigian Sardinian alcohol-preferring (msP) rats.
Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Conditioning, Classical; Ethanol; Fear; Freezing Reaction, Cataleptic; Genotype; Male; Phenotype; Polymorphism, Single Nucleotide; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone | 2015 |
Modulation of enteric neurons by interleukin-6 and corticotropin-releasing factor contributes to visceral hypersensitivity and altered colonic motility in a rat model of irritable bowel syndrome.
Topics: Adolescent; Adult; Aged; Animals; Antibodies, Monoclonal; Case-Control Studies; Disease Models, Animal; Enteric Nervous System; Female; Gastrointestinal Motility; Humans; Interleukin-6; Irritable Bowel Syndrome; Male; Middle Aged; Myenteric Plexus; Neuroimmunomodulation; Neurosecretory Systems; Pain Threshold; Pyrimidines; Pyrroles; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Receptors, Interleukin-6; Visceral Pain; Young Adult | 2014 |
Stress during a critical postnatal period induces region-specific structural abnormalities and dysfunction of the prefrontal cortex via CRF1.
Topics: Animals; Animals, Newborn; Anxiety Disorders; Cognition Disorders; Dendritic Spines; Disease Models, Animal; Female; Hormone Antagonists; Male; Mice, Inbred C57BL; Prefrontal Cortex; Pyramidal Cells; Pyrimidines; Pyrroles; Random Allocation; Receptors, Corticotropin-Releasing Hormone; Stress, Psychological | 2015 |
Antagonism of corticotrophin-releasing factor type 1 receptors attenuates caloric intake of free feeding subordinate female rhesus monkeys in a rich dietary environment.
Topics: Animals; Diet; Energy Intake; Feeding Behavior; Female; Macaca mulatta; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone | 2015 |
The Dorsal Agranular Insular Cortex Regulates the Cued Reinstatement of Cocaine-Seeking, but not Food-Seeking, Behavior in Rats.
Topics: Analysis of Variance; Animals; Baclofen; Cerebral Cortex; Cocaine; Conditioning, Operant; Cues; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Food; GABA Agonists; Male; Microinjections; Muscimol; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration | 2015 |
Urocortin attenuates TGFβ1-induced Snail1 and slug expressions: inhibitory role of Smad7 in Smad2/3 signaling in breast cancer cells.
Topics: Breast Neoplasms; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Peptide Fragments; Pyrimidines; Pyrroles; Signal Transduction; Smad2 Protein; Smad3 Protein; Smad7 Protein; Snail Family Transcription Factors; Transcription Factors; Transforming Growth Factor beta1; Urocortins | 2015 |
The effect of obestatin on anxiety-like behaviour in mice.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Corticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Exploratory Behavior; Ghrelin; Male; Maze Learning; Mice; Oligopeptides; Pyrimidines; Pyrroles | 2015 |
Neuropeptide S Increases locomotion activity through corticotropin-releasing factor receptor 1 in substantia nigra of mice.
Topics: Animals; Gene Expression Regulation; Locomotion; Male; Mice; Neuropeptides; Proto-Oncogene Proteins c-fos; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Substantia Nigra | 2015 |
Stress activates the nucleus incertus and modulates plasticity in the hippocampo-medial prefrontal cortical pathway.
Topics: Animals; Brain Stem; Catheters, Indwelling; Cold Temperature; Disease Models, Animal; Electrodes, Implanted; Fluorescent Antibody Technique; Hippocampus; Long-Term Potentiation; Male; Neural Pathways; Neurons; Neurotransmitter Agents; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Pyrimidines; Pyrroles; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Stress, Psychological; Swimming | 2016 |
Early postnatal stress suppresses the developmental trajectory of hippocampal pyramidal neurons: the role of CRHR1.
Topics: Animals; CA3 Region, Hippocampal; Dendritic Spines; Female; Male; Mice; Mice, Inbred C57BL; Pyramidal Cells; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Stress, Psychological | 2016 |
Behavioral Deficits in Juveniles Mediated by Maternal Stress Hormones in Mice.
Topics: Animals; Anxiety; Behavior, Animal; Depression; Depression, Postpartum; Disease Models, Animal; Female; Maternal Behavior; Mice; Mice, Knockout; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Receptors, GABA-A | 2016 |
Early life stress is a risk factor for excessive alcohol drinking and impulsivity in adults and is mediated via a CRF/GABA(A) mechanism.
Topics: Alcohol Drinking; Amygdala; Animals; Conditioning, Operant; Corticotropin-Releasing Hormone; Ethanol; Female; Impulsive Behavior; Male; Maternal Deprivation; Prefrontal Cortex; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Receptors, GABA-A; Risk Factors; Self Administration; Stress, Psychological; Vitamin B 12 | 2016 |
Corticotropin releasing factor type-1 receptor antagonism in the dorsolateral bed nucleus of the stria terminalis disrupts contextually conditioned fear, but not unconditioned fear to a predator odor.
Topics: Animals; Behavior, Animal; Conditioning, Classical; Corticotropin-Releasing Hormone; Emotions; Fear; Male; Odorants; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Septal Nuclei; Thiazoles | 2016 |
The effects of CRF and urocortins on the sociability of mice.
Topics: Animals; Behavior, Animal; Corticotropin-Releasing Hormone; Male; Mice; Peptide Fragments; Peptides, Cyclic; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Social Behavior; Urocortins | 2017 |
Corticotropin-releasing hormone modulates airway vagal preganglionic neurons of Sprague-Dawley rats at multiple synaptic sites via activation of its type 1 receptors: Implications for stress-associated airway vagal excitation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Autonomic Fibers, Preganglionic; Bicuculline; Corticotropin-Releasing Hormone; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA-A Receptor Antagonists; Male; Medulla Oblongata; Neurons; Peptide Fragments; Peptides, Cyclic; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Sodium Channel Blockers; Synapses; Tetrodotoxin; Vagus Nerve | 2017 |
CRHR1 exacerbates the glial inflammatory response and alters BDNF/TrkB/pCREB signaling in a rat model of global cerebral ischemia: implications for neuroprotection and cognitive recovery.
Topics: Animals; Anxiety; Brain; Brain Ischemia; Brain-Derived Neurotrophic Factor; Central Nervous System Agents; Cognition; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Male; Neuroglia; Neuroimmunomodulation; Neuronal Plasticity; Neuroprotection; Pyrimidines; Pyrroles; Rats, Wistar; Receptor, trkB; Receptors, Corticotropin-Releasing Hormone; Recovery of Function; RNA, Messenger; Signal Transduction | 2017 |
Dopamine and Stress System Modulation of Sex Differences in Decision Making.
Topics: Adrenergic alpha-2 Receptor Antagonists; Amygdala; Animals; Behavior, Animal; Decision Making; Dopamine Agonists; Dopamine D2 Receptor Antagonists; Female; Male; Pyrimidines; Pyrroles; Quinpirole; Rats; Rats, Long-Evans; Receptors, Corticotropin-Releasing Hormone; Receptors, Dopamine D2; Salicylamides; Sex Characteristics; Yohimbine | 2018 |
Corticotrophin releasing factor receptor 1 antagonists prevent chronic stress-induced behavioral changes and synapse loss in aged rats.
Topics: Age Factors; Animals; Anxiety; Behavior; Behavior, Animal; Corticotropin-Releasing Hormone; Depression; Disease Models, Animal; Female; Hypothalamo-Hypophyseal System; Male; Pituitary-Adrenal System; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Stress, Psychological; Synapses | 2018 |
Antagonism of corticotropin releasing factor in the basolateral amygdala of resilient and vulnerable rats: Effects on fear-conditioned sleep, temperature and freezing.
Topics: Adaptation, Psychological; Animals; Basolateral Nuclear Complex; Body Temperature; Corticotropin-Releasing Hormone; Electroencephalography; Fear; Freezing Reaction, Cataleptic; Male; Memory; Physical Conditioning, Animal; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Sleep; Sleep, REM | 2018 |
Paraventricular hypothalamic and amygdalar CRF neurons synapse in the external globus pallidus.
Topics: Action Potentials; Amygdala; Animals; Corticotropin-Releasing Hormone; Female; Globus Pallidus; Green Fluorescent Proteins; In Vitro Techniques; Luminescent Proteins; Male; Mice; Mice, Transgenic; Neurons; Neurotransmitter Agents; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Red Fluorescent Protein; Synapses; Transduction, Genetic | 2018 |
Corticotropin-releasing factor regulates caspase-3 and may protect developing zebrafish from stress-induced apoptosis.
Topics: Animals; Apoptosis; Caspase 3; Corticotropin-Releasing Hormone; Gene Expression Regulation, Developmental; Heat-Shock Response; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Stress, Physiological; Zebrafish | 2018 |
The effect of a corticotropin-releasing factor receptor 1 antagonist on the fear conditioning response in low- and high-anxiety rats after chronic corticosterone administration.
Topics: Animals; Anxiety; Brain; Conditioning, Classical; Corticosterone; Corticotropin-Releasing Hormone; Emotions; Fear; Hypothalamo-Hypophyseal System; Individuality; Male; Pituitary-Adrenal System; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Stress, Psychological | 2019 |
Antagonizing the corticotropin releasing hormone receptor 1 with antalarmin reduces the progression of endometriosis.
Topics: Animals; Disease Models, Animal; Disease Progression; Endometriosis; Female; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Treatment Outcome | 2018 |
The blockade of corticotropin-releasing factor 1 receptor attenuates anxiety-related symptoms and hypothalamus-pituitary-adrenal axis reactivity in mice with mild traumatic brain injury.
Topics: Adrenocorticotropic Hormone; Animals; Anxiety; Anxiety Disorders; Brain Concussion; Corticosterone; Corticotropin-Releasing Hormone; Disease Models, Animal; Hypothalamo-Hypophyseal System; Male; Mice; Mice, Inbred Strains; Pituitary-Adrenal System; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Stress, Physiological | 2019 |
Role of corticotropin-releasing factor on bladder function in rats with psychological stress.
Topics: Animals; Case-Control Studies; Corticotropin-Releasing Hormone; Disease Models, Animal; Injections, Intraperitoneal; Male; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Corticotropin-Releasing Hormone; Stress, Psychological; Urinary Bladder; Urination | 2019 |
Short treatment with antalarmin alters adrenal gland receptors in the rat model of endometriosis.
Topics: Adrenal Glands; Animals; Disease Models, Animal; Endometriosis; Female; Pituitary-Adrenal System; Pyrimidines; Pyrroles; Rats; Receptors, Corticotropin-Releasing Hormone; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; RNA, Messenger; Up-Regulation | 2020 |
Corticotropin-releasing factor protects against ammonia neurotoxicity in isolated larval zebrafish brains.
Topics: Ammonia; Animals; Brain; Cell Death; Corticotropin-Releasing Hormone; Dizocilpine Maleate; Gene Expression Regulation, Developmental; Larva; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Receptors, N-Methyl-D-Aspartate; Zebrafish | 2020 |
Role of corticotropin-releasing hormone in the impact of chronic stress during pregnancy on inducing depression in male offspring mice.
Topics: Animals; Behavior, Animal; Corticotropin-Releasing Hormone; Depression; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Hormone Antagonists; Male; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Receptors, N-Methyl-D-Aspartate; Stress, Psychological | 2020 |
Basolateral amygdala corticotropin-releasing factor receptor type 1 regulates context-cocaine memory strength during reconsolidation in a sex-dependent manner.
Topics: Animals; Basolateral Nuclear Complex; Cocaine; Cocaine-Related Disorders; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Female; Male; Memory; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone | 2021 |
Corticotropin-Releasing Factor Aggravates Ischemic Stroke Injury by the Inflammatory Activation of Microglia.
Topics: Animals; Corticotropin-Releasing Hormone; Disease Models, Animal; Inflammation; Ischemic Stroke; Male; Mice; Microglia; Neurons; NF-kappa B; Peptide Fragments; Peptides, Cyclic; Phosphorylation; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone | 2022 |