pyrroles has been researched along with alprostadil in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (21.05) | 18.7374 |
| 1990's | 9 (47.37) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 3 (15.79) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kamei, C; Mukai, T; Tasaka, K | 1 |
| Deguchi, K; Komada, F; Morita, K; Nishikawa, M; Shirakawa, S | 1 |
| Adachi, H; Irie, T; Noda, K; Saita, M; Uekama, K; Yano, T | 1 |
| Adachi, H; Irie, T; Manako, T; Saita, M; Uekama, K; Yano, T | 1 |
| Deguchi, K; Nishikawa, M; Saitoh, M; Shirakawa, S | 1 |
| Lanza, FL | 1 |
| Aspinall, RL; Davis, RE; Lanza, FL; Rack, MF; Rubin, A; Swabb, EA | 1 |
| Heleniak, EP; Lamola, SW | 1 |
| Imazu, C; Ishii, K; Kadokawa, T; Nakamura, H; Shimizu, M; Yokoyama, Y | 1 |
| Donatucci, CF; Hsu, GL; Lue, TF; Martinez-Piñeiro, L; Tanagho, EA; Trigo-Rocha, F | 1 |
| al-Rashed, S; Hellewell, PG; Rossi, AG; Teixeira, MM | 1 |
| Champion, HC; Kadowitz, PJ | 1 |
| Huang, LJ; Kuo, SC; Raung, SL; Wang, JP | 1 |
| Conde, M; Porras, T; Rosado, JA; Sage, SO | 1 |
| Kamio, K; Kawasaki, S; Kobayashi, T; Liu, X; Mao, LJ; Rennard, SI; Shen, L; Sugiura, H; Togo, S; Wang, XQ | 1 |
| Hussar, DA | 1 |
| Fang, W; Li, H; Liang, Y; Mu, Y; Su, L; Zhou, L | 1 |
| Hayashi, Y; Liu, X; Morinaga, S; Nakanishi, H; Wu, Z; Yokoyama, T; Zhang, J | 1 |
| Fu, Y; He, YH; Li, Y; Lin, SD; Liu, QC; Long, J; Mu, MY; Yang, FW | 1 |
2 trial(s) available for pyrroles and alprostadil
| Article | Year |
|---|---|
A double-blind study of prophylactic effect of misoprostol on lesions of gastric and duodenal mucosa induced by oral administration of tolmetin in healthy subjects.
Topics: Administration, Oral; Adult; Alprostadil; Anti-Ulcer Agents; Clinical Trials as Topic; Double-Blind Method; Duodenum; Endoscopy; Female; Gastric Mucosa; Humans; Intestinal Mucosa; Male; Misoprostol; Pyrroles; Tolmetin | 1986 |
Double-blind, placebo-controlled endoscopic comparison of the mucosal protective effects of misoprostol versus cimetidine on tolmetin-induced mucosal injury to the stomach and duodenum.
Topics: Adult; Alprostadil; Anti-Ulcer Agents; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Duodenal Ulcer; Duodenoscopy; Gastric Mucosa; Gastroscopy; Humans; Intestinal Mucosa; Middle Aged; Misoprostol; Pyrroles; Stomach Ulcer; Tolmetin | 1988 |
17 other study(ies) available for pyrroles and alprostadil
| Article | Year |
|---|---|
Histamine-induced depolarization and the cyclic AMP--protein kinase A system in isolated guinea pig adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adipose Tissue; Alprostadil; Animals; Carbazoles; Colforsin; Cyclic AMP; Electrophysiology; Epididymis; Guinea Pigs; Histamine; In Vitro Techniques; Indoles; Insulin; Isoproterenol; Male; Membrane Potentials; Protein Kinase C; Protein Kinases; Pyrroles; Rats; Rats, Wistar | 1992 |
Inhibition of platelet aggregation by the cAMP-phosphodiesterase inhibitor, cilostamide, may not be associated with activation of cAMP-dependent protein kinase.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Alprostadil; Blood Platelets; Calcium; Carbazoles; Cyclic AMP; Humans; Indoles; Phosphorylation; Platelet Aggregation Inhibitors; Protein Kinases; Pyrroles; Quinolones; Thromboxane A2 | 1992 |
Improved transdermal delivery of prostaglandin E1 through hairless mouse skin: combined use of carboxymethyl-ethyl-beta-cyclodextrin and penetration enhancers.
Topics: Administration, Cutaneous; Alprostadil; Animals; Azepines; beta-Cyclodextrins; Cyclodextrins; Drug Carriers; Female; Mice; Mice, Hairless; Ointments; Pyrroles; Regional Blood Flow; Skin; Skin Absorption | 1992 |
Inhibitory effect of prostaglandin E1 on laurate-induced peripheral vascular occlusive sequelae in rabbits: optimized topical formulation with beta-cyclodextrin derivative and penetration enhancer HPE-101.
Topics: Administration, Topical; Alprostadil; Animals; Cyclodextrins; Drug Carriers; Drug Combinations; Ear; Lauric Acids; Male; Ointments; Peripheral Vascular Diseases; Pyrroles; Rabbits | 1992 |
[Intracellular actions of antiplatelet drugs which affect cyclic AMP metabolism in platelets--their effects on Ca2+ mobilization and protein phosphorylation in human platelets].
Topics: Alprostadil; Blood Platelets; Calcium; Carbazoles; Colforsin; Cyclic AMP; Humans; Indoles; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Kinase C; Pyrroles; Thromboxane A2 | 1990 |
A new prostaglandin disturbance syndrome in schizophrenia: delta-6-pyroluria.
Topics: Alprostadil; Aspartate Aminotransferases; Fatty Acid Desaturases; Fatty Acids, Essential; Humans; Insulin; Linoleic Acid; Linoleic Acids; Linoleoyl-CoA Desaturase; Mutation; Prostaglandins; Pyrroles; Schizophrenia; Syndrome | 1986 |
Site of analgesic action of zomepirac sodium, a potent non-narcotic analgesic in experimental animals.
Topics: Alprostadil; Analgesics; Animals; Ascitic Fluid; Bradykinin; Dogs; Hypertension; Injections, Intraventricular; Male; Naloxone; Pain; Prostaglandins E; Pyrroles; Rats; Rats, Inbred Strains; Tolmetin | 1983 |
Intracellular mechanism of penile erection in monkeys.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Animals; Benzopyrans; Cromakalim; Cyclic AMP; Cyclic GMP; Ethylmaleimide; Macaca nemestrina; Male; Methylene Blue; Nitroprusside; Penile Erection; Penis; Phosphodiesterase Inhibitors; Purinones; Pyrroles; Ultrasonography | 1994 |
Characterization of the prostanoid receptors mediating inhibition of PAF-induced aggregation of guinea-pig eosinophils.
Topics: Alprostadil; Analysis of Variance; Animals; Anti-Ulcer Agents; Carbazoles; Cell Aggregation; Dinoprostone; Dose-Response Relationship, Drug; Eosinophils; Female; Guinea Pigs; Indoles; Misoprostol; Oxytocics; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prostaglandin D2; Prostaglandins E, Synthetic; Prostanoic Acids; Protein Kinase C; Pyrroles; Receptors, Prostaglandin; Structure-Activity Relationship | 1997 |
Vasodilator responses to acetylcholine, bradykinin, and substance P are mediated by a TEA-sensitive mechanism.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Albuterol; Alprostadil; Analysis of Variance; Angiotensin II; Animals; Benzopyrans; Blood Pressure; Bradykinin; Cats; Cromakalim; Endothelium, Vascular; Female; Glyburide; Heart Rate; Hindlimb; Hydrazines; Isradipine; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitrogen Oxides; Nitroprusside; Norepinephrine; Penicillamine; Prostaglandin Endoperoxides, Synthetic; Pyrroles; S-Nitroso-N-Acetylpenicillamine; Substance P; Tetraethylammonium; Tetraethylammonium Compounds; Thromboxane A2; Vasoactive Intestinal Peptide; Vasodilation; Vasodilator Agents | 1997 |
Involvement of cyclic AMP generation in the inhibition of respiratory burst by 2-phenyl-4-quinolone (YT-1) in rat neutrophils.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Bucladesine; Calcium; Carbazoles; Cardiotonic Agents; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cytosol; Indoles; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Protein Kinase C; Pyrroles; Quinolones; Rats; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
Cyclic nucleotides modulate store-mediated calcium entry through the activation of protein-tyrosine phosphatases and altered actin polymerization in human platelets.
Topics: Actins; Adenosine Diphosphate; Alprostadil; Arsenicals; Blood Platelets; Calcium; Carbazoles; Cyclic AMP; Cyclic GMP; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Humans; In Vitro Techniques; Indoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitroprusside; Phosphorylation; Platelet Activation; Platelet Aggregation Inhibitors; Protein Tyrosine Phosphatases; Pyrroles; Thapsigargin; Thrombin; Vanadates | 2001 |
Prostaglandin E(2) protects human lung fibroblasts from cigarette smoke extract-induced apoptosis via EP(2) receptor activation.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Apoptosis; Carbazoles; Caspases; Cell Line; Cyclic AMP-Dependent Protein Kinases; Dideoxyadenosine; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Humans; Indoles; Lung; Nicotiana; Pyrroles; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; RNA, Small Interfering; Signal Transduction; Smoke; Thiophenes; Triazoles | 2007 |
New drugs 07, part I.
Topics: Abatacept; Acetanilides; Alprostadil; Anidulafungin; Antidiuretic Hormone Receptor Antagonists; Antifungal Agents; Antineoplastic Agents; Arabinonucleosides; Benzazepines; Benzenesulfonates; Drug Approval; Drug Interactions; Drug Monitoring; Drug Therapy; Echinocandins; Fatty Acids; Humans; Hypoglycemic Agents; Immunoconjugates; Immunosuppressive Agents; Indoles; Insulin; Insulin Detemir; Insulin, Long-Acting; Intercellular Signaling Peptides and Proteins; Lenalidomide; Lubiprostone; Niacinamide; Patient Education as Topic; Peptides, Cyclic; Phenylurea Compounds; Piperazines; Pyridines; Pyrroles; Ranolazine; Sorafenib; Sunitinib; Thalidomide; United States | 2007 |
Effect of prostaglandin E1 on TNF-induced vascular inflammation in human umbilical vein endothelial cells.
Topics: Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Atorvastatin; Cell Adhesion; Cell Line; Cell Survival; E-Selectin; Endothelial Cells; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Heptanoic Acids; Humans; Intercellular Adhesion Molecule-1; Pyrroles; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2010 |
An EP2 Agonist Facilitates NMDA-Induced Outward Currents and Inhibits Dendritic Beading through Activation of BK Channels in Mouse Cortical Neurons.
Topics: Alprostadil; Animals; Carbazoles; Dinoprostone; In Vitro Techniques; Indoles; Large-Conductance Calcium-Activated Potassium Channels; Male; Methyl Ethers; Mice; Mice, Inbred C57BL; Pyrroles; Receptors, N-Methyl-D-Aspartate; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype | 2016 |
Prostaglandin E1 protects hepatocytes against endoplasmic reticulum stress-induced apoptosis via protein kinase A-dependent induction of glucose-regulated protein 78 expression.
Topics: Alprostadil; Apoptosis; Carbazoles; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Eukaryotic Initiation Factor-2; Heat-Shock Proteins; Hep G2 Cells; Hepatocytes; Humans; Isoquinolines; Phosphorylation; Pyrroles; RNA Interference; RNA, Small Interfering; Signal Transduction; Sulfonamides; Thapsigargin; Transcription Factor CHOP; Unfolded Protein Response; X-Box Binding Protein 1 | 2017 |