Page last updated: 2024-08-18

pyrroles and allopurinol

pyrroles has been researched along with allopurinol in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19905 (18.52)18.7374
1990's1 (3.70)18.2507
2000's10 (37.04)29.6817
2010's11 (40.74)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hessinger, DA; Hosmane, RS; MacCartney, LB; Schneller, SW1
Hong, KW; Kim, CD; Lee, WS; Rhim, BY1
Mehlhorn, R; Sies, H1
Baker, BR; Siebeneick, HU1
Elion, GB; Hitchings, GH; Krenitsky, TA; Neil, SM1
Fridovich, I; Robertson, P1
Le Moigne, F; Mercier, A; Olive, G; Rockenbauer, A; Tordo, P1
Bifulco, G; Bruno, I; Casapullo, A; Cutignano, A; Debitus, C; Gomez-Paloma, L; Riccio, R1
Halpern, HJ; Ichikawa, K; Mailer, C; Nielsen, R; Pou, S; Robinson, BH; Rosen, GM; Tsai, P1
Ilangovan, G; Kuppusamy, P; Zweier, JL1
Chinje, E; Douglas, KT; Freeman, S; Gbaj, A; Reigan, P; Stratford, IJ1
Arslan, F; Kiliç, E; Yaşar, A1
Ishida, K; Iwanaga, T; Karakawa, T; Kitamado, M; Maruyama, K; Mitani, Y; Muramoto, Y; Nabeshima, T; Nakagawa, K; Sasamoto, K; Sato, K1
Jia, Z; Li, Y; Mahaney, JE; Misra, BR; Misra, HP; Zhu, H1
Bardelang, D; Finet, JP; Hardy, M; Jicsinszky, L; Karoui, H; Ouari, O; Rockenbauer, A; Rosas, R; Tordo, P1
Bouteiller, JC; Lauricella, RP; Tuccio, BN1
Alcaino, H; Castro, PF; Chiong, M; Gabrielli, LA; Garcia, L; Godoy, I; Greig, D; Lavandero, S; López, R; Mellado, R; Navarro, M; Nogerol, C; Tapia, F; Verdejo, HE1
Kohno, M; Mokudai, T; Niwano, Y; Sato, E1
Arslan, F; Çete, S; Dolmaci, N; Yaşar, A1
Catar, R; Chaykovska, L; Dragun, D; Fuller, TF; Haller, M; Hoff, U; Kusch, A; Pützer, J; Troppmair, J1
Amin, A; Badr El-Din, NK; Choi, SK; Kadowitz, P; Kevil, CG; Matrougui, K; Navar, LG; Osman-Elazeik, Y; Trebak, M1
Chen, YC; Cheng, KT; Lee, WR; Shen, SC; Tsai, HH; Wang, PH1
Arslan, H; Çete, S; Görgülü, M; Yaşar, A1
Abe, S; Azuma, A; Gemma, A; Kamio, K; Kubota, K; Matsuda, K; Saito, Y; Tanaka, T1
Abbas Ali Noma, S; Ateş, B; Kıbrız, İE; Saçmacı, M; Taşkın Tok, T; Yıldırım, İ1
Baldini, E; Bernardini, G; Jacomelli, G; Micheli, V; Mugnaini, C; Santucci, A1
Celik, E; Kaplan, M; Otles, S; Ozsoz, M; Sahyar, BY1

Trials

1 trial(s) available for pyrroles and allopurinol

ArticleYear
Xanthine-oxidase inhibitors and statins in chronic heart failure: effects on vascular and functional parameters.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2011, Volume: 30, Issue:4

    Topics: Allopurinol; Atorvastatin; Double-Blind Method; Endothelium, Vascular; Enzyme Inhibitors; Female; Heart Failure; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Oxidative Stress; Pyrroles; Regional Blood Flow; Treatment Outcome; Xanthine Oxidase

2011

Other Studies

26 other study(ies) available for pyrroles and allopurinol

ArticleYear
Synthesis and xanthine oxidase inhibitory analysis of 1H-pyrrolo[3,2-c]pyridine-4,6(5H,7H)-dione (3,7-dideazaxanthine) and two of its derivatives.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:9

    Topics: Kinetics; Pyridones; Pyrroles; Spectrophotometry, Ultraviolet; Xanthine Oxidase

1978
Similarities between effects of superoxide-mediated endothelium-derived relaxing factor and cromakalim.
    The American journal of physiology, 1992, Volume: 262, Issue:5 Pt 2

    Topics: Animals; Aorta, Thoracic; Benzopyrans; Cromakalim; Cyclic GMP; Female; Hypoxanthine; Hypoxanthines; Male; Mesenteric Arteries; Nitric Oxide; Pyrroles; Rabbits; Rubidium; Superoxides; Vasodilation; Vasodilator Agents; Xanthine Oxidase

1992
Mutagenicity of nitroxide-free radicals.
    Archives of biochemistry and biophysics, 1986, Nov-15, Volume: 251, Issue:1

    Topics: Cyclic N-Oxides; Free Radicals; Mutagenicity Tests; Mutagens; Pyrroles; Pyrrolidines; Salmonella typhimurium; Spin Labels; Xanthine Oxidase

1986
Affinity chromatography of guanine deaminase and xanthine oxidase.
    Methods in enzymology, 1974, Volume: 34

    Topics: Aminohydrolases; Animals; Cattle; Chromatography, Affinity; Guanine; Ligands; Pyrimidines; Pyrroles; Rats; Sepharose; Xanthine Oxidase

1974
A comparison of the specificities of xanthine oxidase and aldehyde oxidase.
    Archives of biochemistry and biophysics, 1972, Volume: 150, Issue:2

    Topics: Alcohols; Aldehydes; Amines; Animals; Cattle; Chlorine; Ferricyanides; Imidazoles; Ketones; Kinetics; Liver; Methylamines; Milk; Nitriles; Oxidoreductases; Pteridines; Purines; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Rabbits; Spectrophotometry; Structure-Activity Relationship; Sulfhydryl Compounds; Sulfides; Sulfones; Thiazoles; Xanthine Oxidase

1972
A reaction of the superoxide radical with tetrapyrroles.
    Archives of biochemistry and biophysics, 1982, Volume: 213, Issue:2

    Topics: Bilirubin; Biliverdine; Catalase; Kinetics; Oxygen; Pigments, Biological; Protoporphyrins; Pyrroles; Superoxide Dismutase; Superoxides; Tetrapyrroles; Uroporphyrins; Xanthine Oxidase

1982
2-ethoxycarbonyl-2-methyl-3,4-dihydro-2H-pyrrole-1-oxide: evaluation of the spin trapping properties.
    Free radical biology & medicine, 2000, Feb-01, Volume: 28, Issue:3

    Topics: Animals; Buffers; Cattle; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Erythrocytes; Free Radical Scavengers; Indicators and Reagents; Molecular Structure; Phosphates; Pyrroles; Spin Labels; Superoxide Dismutase; Xanthine Oxidase

2000
Makaluvamine P, a new cytotoxic pyrroloiminoquinone from Zyzzya cf. fuliginosa.
    Journal of natural products, 2001, Volume: 64, Issue:10

    Topics: Animals; Antineoplastic Agents; Australia; Enzyme Inhibitors; Humans; KB Cells; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Nasopharyngeal Neoplasms; Porifera; Pyrroles; Quinolones; Toxicity Tests; Tumor Cells, Cultured; Xanthine Oxidase

2001
Esters of 5-carboxyl-5-methyl-1-pyrroline N-oxide: a family of spin traps for superoxide.
    The Journal of organic chemistry, 2003, Oct-03, Volume: 68, Issue:20

    Topics: Binding, Competitive; Cyclic N-Oxides; Cytochromes c; Electron Spin Resonance Spectroscopy; Esters; Half-Life; Hydrogen-Ion Concentration; Kinetics; Pyrroles; Spin Labels; Spin Trapping; Superoxides; Xanthine; Xanthine Oxidase

2003
Microximetry: simultaneous determination of oxygen consumption and free radical production using electron paramagnetic resonance spectroscopy.
    Methods in enzymology, 2004, Volume: 381

    Topics: Animals; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Indoles; Molecular Probes; Organometallic Compounds; Oxygen; Oxygen Consumption; Pyrroles; Superoxides; Xanthine; Xanthine Oxidase

2004
Synthesis and enzymatic evaluation of xanthine oxidase-activated prodrugs based on inhibitors of thymidine phosphorylase.
    Bioorganic & medicinal chemistry letters, 2004, Nov-01, Volume: 14, Issue:21

    Topics: Antineoplastic Agents; Escherichia coli; Humans; Prodrugs; Pyrimidines; Pyrroles; Pyrrolidines; Thymidine Phosphorylase; Xanthine Oxidase

2004
An amperometric biosensor for xanthine determination prepared from xanthine oxidase immobilized in polypyrrole film.
    Artificial cells, blood substitutes, and immobilization biotechnology, 2006, Volume: 34, Issue:1

    Topics: Animals; Biosensing Techniques; Cattle; Electrochemistry; Enzymes, Immobilized; Humans; Polymers; Pyrroles; Sensitivity and Specificity; Xanthine; Xanthine Oxidase

2006
Applicability of new spin trap agent, 2-diphenylphosphinoyl-2-methyl-3,4-dihydro-2H-pyrrole N-oxide, in biological system.
    Biochemical and biophysical research communications, 2008, May-23, Volume: 370, Issue:1

    Topics: Cell Line; Cell-Free System; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Humans; Kinetics; Neutrophils; Pyrroles; Spin Labels; Spin Trapping; Superoxides; Tetradecanoylphorbol Acetate; Xanthine; Xanthine Oxidase

2008
EPR studies on the superoxide-scavenging capacity of the nutraceutical resveratrol.
    Molecular and cellular biochemistry, 2008, Volume: 313, Issue:1-2

    Topics: Dietary Supplements; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Oxygen Consumption; Pyrroles; Resveratrol; Spin Labels; Stilbenes; Superoxides; Uric Acid; Xanthine; Xanthine Oxidase

2008
Improving the trapping of superoxide radical with a beta-cyclodextrin- 5-diethoxyphosphoryl-5-methyl-1-pyrroline-N-oxide (DEPMPO) conjugate.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2009, Oct-26, Volume: 15, Issue:42

    Topics: beta-Cyclodextrins; Electron Spin Resonance Spectroscopy; Kinetics; Pyrroles; Spin Labels; Superoxides; Xanthine Oxidase

2009
Evidence of overestimation of rate constants for the superoxide trapping by nitrones in aqueous media.
    Physical chemistry chemical physics : PCCP, 2005, Jan-21, Volume: 7, Issue:2

    Topics: Cyclic N-Oxides; Hypoxanthine; Kinetics; Models, Molecular; Nitrogen Oxides; Pyrroles; Superoxides; Water; Xanthine; Xanthine Oxidase

2005
Kinetic analysis of reactive oxygen species generated by the in vitro reconstituted NADPH oxidase and xanthine oxidase systems.
    Journal of biochemistry, 2011, Volume: 150, Issue:2

    Topics: Cyclic N-Oxides; Flavin-Adenine Dinucleotide; Hydrogen Peroxide; Kinetics; NADP; NADPH Oxidases; Pyrroles; Reactive Oxygen Species; Spin Trapping; Superoxides; Xanthine Oxidase

2011
An amperometric biosensor for fish freshness detection from xanthine oxidase immobilized in polypyrrole-polyvinylsulphonate film.
    Artificial cells, blood substitutes, and immobilization biotechnology, 2012, Volume: 40, Issue:4

    Topics: Animals; Biocatalysis; Biosensing Techniques; Electrochemistry; Electrodes; Enzymes, Immobilized; Fishes; Food Analysis; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hypoxanthine; Methylene Blue; Polymers; Polyvinyls; Pyrroles; Reproducibility of Results; Sulfonic Acids; Temperature; Uric Acid; Xanthine; Xanthine Oxidase

2012
Protein kinase C inhibition ameliorates posttransplantation preservation injury in rat renal transplants.
    Transplantation, 2012, Oct-15, Volume: 94, Issue:7

    Topics: Adenosine; Allopurinol; Animals; Apoptosis; Biomarkers; Blotting, Western; Cell Proliferation; Cold Temperature; Creatinine; Cytokines; Cytoprotection; Delayed Graft Function; Glutathione; Immunohistochemistry; Inflammation Mediators; Insulin; Kidney; Kidney Transplantation; Male; Mycophenolic Acid; Organ Preservation; Organ Preservation Solutions; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles; Quinazolines; Raffinose; Rats; Rats, Inbred Lew; Real-Time Polymerase Chain Reaction; Reperfusion Injury; Signal Transduction; Time Factors

2012
Sodium nitrite therapy rescues ischemia-induced neovascularization and blood flow recovery in hypertension.
    Pflugers Archiv : European journal of physiology, 2012, Volume: 464, Issue:6

    Topics: Allopurinol; Angiotensin II; Animals; Arterial Pressure; Capillaries; Cyclic AMP; Cyclic GMP; Femoral Artery; Hindlimb; Hypertension; Indoles; Ischemia; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Neovascularization, Pathologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Proto-Oncogene Proteins c-akt; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Regional Blood Flow; Sodium Nitrite; Xanthine Dehydrogenase

2012
Propionibacterium acnes-induced iNOS and COX-2 protein expression via ROS-dependent NF-κB and AP-1 activation in macrophages.
    Journal of dermatological science, 2013, Volume: 69, Issue:2

    Topics: Allopurinol; Animals; Cell Line; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gram-Positive Bacterial Infections; Imidazoles; Luciferases; Macrophages; MAP Kinase Signaling System; Mice; NADPH Oxidases; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Propionibacterium acnes; Pyrroles; Reactive Oxygen Species; Transcription Factor AP-1; Xanthine Oxidase

2013
Preparing a new biosensor for hypoxanthine determination by immobilization of xanthine oxidase and uricase in polypyrrole-polyvinyl sulphonate film.
    Artificial cells, nanomedicine, and biotechnology, 2013, Volume: 41, Issue:5

    Topics: Animals; Arylsulfonates; Biosensing Techniques; Cell Extracts; Enzymes, Immobilized; Hypoxanthine; Muscles; Polymerization; Polymers; Polyvinyls; Protein Stability; Pyrroles; Salmon; Urate Oxidase; Xanthine Oxidase

2013
Cyclic mechanical stretch-induced oxidative stress occurs via a NOX-dependent mechanism in type II alveolar epithelial cells.
    Respiratory physiology & neurobiology, 2017, Volume: 242

    Topics: Alveolar Epithelial Cells; Cell Death; Cell Line; Cell Survival; Dinoprost; Enzyme Inhibitors; Humans; Imidazoles; Mitochondria; NADPH Oxidases; Oxidative Stress; Periodicity; Pyrazoles; Pyrazolones; Pyridines; Pyridones; Pyrroles; Reactive Oxygen Species; Stress, Physiological; Time Factors; Xanthine Oxidase

2017
Xanthine oxidase inhibitory activity of new pyrrole carboxamide derivatives: In vitro and in silico studies.
    Archiv der Pharmazie, 2018, Volume: 351, Issue:10

    Topics: Animals; Cattle; Dose-Response Relationship, Drug; Enzyme Inhibitors; Milk; Molecular Docking Simulation; Molecular Structure; Pyrroles; Structure-Activity Relationship; Xanthine Oxidase

2018
Inhibiting PNP for the therapy of hyperuricemia in Lesch-Nyhan disease: Preliminary in vitro studies with analogues of immucillin-G.
    Journal of inherited metabolic disease, 2019, Volume: 42, Issue:1

    Topics: Allopurinol; Cells, Cultured; Enzyme Inhibitors; Humans; Hyperuricemia; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Purine-Nucleoside Phosphorylase; Purines; Pyrimidinones; Pyrroles; Reproducibility of Results; Uric Acid; Xanthine

2019
Electrochemical xanthine detection by enzymatic method based on Ag doped ZnO nanoparticles by using polypyrrole.
    Bioelectrochemistry (Amsterdam, Netherlands), 2019, Volume: 130

    Topics: Biosensing Techniques; Electrochemical Techniques; Enzymes, Immobilized; Food Analysis; Limit of Detection; Nanoparticles; Polymers; Pyrroles; Seafood; Silver; Xanthine; Xanthine Oxidase; Zinc Oxide

2019