Page last updated: 2024-08-18

pyrroles and ageladine a

pyrroles has been researched along with ageladine a in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (36.36)29.6817
2010's12 (54.55)24.3611
2020's2 (9.09)2.80

Authors

AuthorsStudies
Fujita, M; Fusetani, N; Itoh, Y; Matsunaga, S; Nakao, Y; Seiki, M; Van Soest, RW; Yamashita, J1
Meketa, ML; Weinreb, SM2
Karuso, P; Shengule, SR1
Fusetani, N; Meketa, ML; Nakao, Y; Weinreb, SM1
Ando, N; Terashima, S3
Bickmeyer, U; Grube, A; Klings, KW; Köck, M1
Horne, DA; Jove, R; Ma, Y; Nam, S; Yakushijin, K1
Bickmeyer, U; Heine, M; Karuso, P; Köck, M; Münd, D; Podbielski, I1
Blairvacq, M; Karuso, P; Loa-Kum-Cheung, WL; Meijer, L; Nakao, Y; Parish, CR; Shengule, SR1
Bickmeyer, U1
Bickmeyer, U; Obermann, D; Wägele, H1
Abele, D; Bickmeyer, U; Rivera-Ingraham, GA1
Abele, D; Bickmeyer, U; Dringen, R; Petters, C; Rivera-Ingraham, G; Tietje, K1
Awal, S; Bickmeyer, U; Dringen, R; Jordan, S; Mordhorst, T; Petters, C; Sartoris, L1
Arai, D; Fukase, K; Iwata, T; Kurbangalieva, A; Nakao, Y; Otsuka, S; Tanaka, K; Tsubokura, K1
Kaufman, TS; Larghi, EL; Vargas, DF1
Bickmeyer, U; Koch, F; Petety Mukagatare, L; Sartoris, FJ; Silalahi, R; Thoms, S1
Bickmeyer, U; Koch, F; Peter, C; Sartoris, FJ; Thoms, S2

Reviews

1 review(s) available for pyrroles and ageladine a

ArticleYear
The 6π-azaelectrocyclization of azatrienes. Synthetic applications in natural products, bioactive heterocycles, and related fields.
    Natural product reports, 2019, 02-20, Volume: 36, Issue:2

    Topics: Alkaloids; Aza Compounds; Biological Products; Chemistry Techniques, Synthetic; Cyclization; Histamine Agonists; Piperidines; Pyridines; Pyrroles; Quinazolines; Quinolizines; Sesquiterpenes

2019

Other Studies

21 other study(ies) available for pyrroles and ageladine a

ArticleYear
Ageladine A: an antiangiogenic matrixmetalloproteinase inhibitor from the marine sponge Agelas nakamurai.
    Journal of the American Chemical Society, 2003, Dec-24, Volume: 125, Issue:51

    Topics: Alkaloids; Angiogenesis Inhibitors; Animals; Enzyme Inhibitors; Matrix Metalloproteinase Inhibitors; Nuclear Magnetic Resonance, Biomolecular; Porifera; Pyrroles; Spectrometry, Mass, Fast Atom Bombardment

2003
Total synthesis of ageladine A, an angiogenesis inhibitor from the marine sponge Agelas nakamurai.
    Organic letters, 2006, Mar-30, Volume: 8, Issue:7

    Topics: Agelas; Angiogenesis Inhibitors; Animals; Catalysis; Hydrocarbons, Brominated; Marine Biology; Molecular Structure; Pyrroles

2006
Concise total synthesis of the marine natural product ageladine A.
    Organic letters, 2006, Aug-31, Volume: 8, Issue:18

    Topics: Agelas; Animals; Molecular Structure; Pyrroles

2006
A new total synthesis of the zinc matrixmetalloproteinase inhibitor ageladine A featuring a biogenetically patterned 6pi-2-azatriene electrocyclization.
    Organic letters, 2007, Mar-01, Volume: 9, Issue:5

    Topics: Aza Compounds; Cyclization; Electrons; Heterocyclic Compounds; Metalloproteases; Molecular Structure; Protease Inhibitors; Pyrroles; Zinc

2007
Application of a 6pi-1-azatriene electrocyclization strategy to the total synthesis of the marine sponge metabolite ageladine A and biological evaluation of synthetic analogues.
    The Journal of organic chemistry, 2007, Jun-22, Volume: 72, Issue:13

    Topics: Animals; Aza Compounds; Cyclization; Electrons; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Molecular Structure; Oceans and Seas; Porifera; Pyrroles

2007
Synthesis and matrix metalloproteinase (MMP)-12 inhibitory activity of ageladine A and its analogs.
    Bioorganic & medicinal chemistry letters, 2007, Aug-15, Volume: 17, Issue:16

    Topics: Matrix Metalloproteinase Inhibitors; Molecular Structure; Pyrroles; Structure-Activity Relationship

2007
Ageladine A, a pyrrole-imidazole alkaloid from marine sponges, is a pH sensitive membrane permeable dye.
    Biochemical and biophysical research communications, 2008, Aug-29, Volume: 373, Issue:3

    Topics: Agelas; Alkaloids; Animals; Cell Membrane; Fluorescence; Fluorescent Dyes; Hydrogen-Ion Concentration; Imidazoles; PC12 Cells; Permeability; Pyrroles; Rats

2008
Synthesis of novel ageladine A analogs showing more potent matrix metalloproteinase (MMP)-12 inhibitory activity than the natural product.
    Bioorganic & medicinal chemistry letters, 2009, Sep-15, Volume: 19, Issue:18

    Topics: Agelas; Animals; Matrix Metalloproteinase 12; Matrix Metalloproteinase Inhibitors; Pyrroles; Structure-Activity Relationship

2009
Synthesis and anticancer activities of ageladine A and structural analogs.
    Bioorganic & medicinal chemistry letters, 2010, Jan-01, Volume: 20, Issue:1

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Imidazoles; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Oxidation-Reduction; Pyrroles; Structure-Activity Relationship

2010
Tracking of fast moving neuronal vesicles with ageladine A.
    Biochemical and biophysical research communications, 2010, Nov-19, Volume: 402, Issue:3

    Topics: Animals; Cytoplasmic Vesicles; Fluorescent Dyes; Hippocampus; Neurons; PC12 Cells; Pyrroles; Rats; Staining and Labeling

2010
A one-pot synthesis and biological activity of ageladine A and analogues.
    Journal of medicinal chemistry, 2011, Apr-14, Volume: 54, Issue:7

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Matrix Metalloproteinase Inhibitors; Neovascularization, Pathologic; Protein Kinase Inhibitors; Protein Kinases; Pyrroles

2011
Synthesis and matrix metalloproteinase-12 inhibitory activity of ageladine A analogs.
    Chemical & pharmaceutical bulletin, 2011, Volume: 59, Issue:5

    Topics: Antineoplastic Agents; Bromine; Imidazoles; Matrix Metalloproteinase Inhibitors; Models, Chemical; Pyrroles; Structure-Activity Relationship

2011
The alkaloid Ageladine A, originally isolated from marine sponges, used for pH-sensitive imaging of transparent marine animals.
    Marine drugs, 2012, Volume: 10, Issue:1

    Topics: Animals; Hydrogen-Ion Concentration; Platyhelminths; Porifera; Pyrroles; Scyphozoa; Sea Anemones

2012
Incorporated nematocysts in Aeolidiella stephanieae (Gastropoda, Opisthobranchia, Aeolidoidea) mature by acidification shown by the pH sensitive fluorescing alkaloid Ageladine A.
    Toxicon : official journal of the International Society on Toxinology, 2012, Volume: 60, Issue:6

    Topics: Alkaloids; Animals; Cnidaria; Fluorescence; Fluorescent Dyes; Gastropoda; Hydrogen-Ion Concentration; Nematocyst; Pyrroles

2012
The physiological response of the marine platyhelminth Macrostomum lignano to different environmental oxygen concentrations.
    The Journal of experimental biology, 2013, Jul-15, Volume: 216, Issue:Pt 14

    Topics: Animals; Dicarbethoxydihydrocollidine; Environment; Fluoresceins; Fluorometry; Hydrogen-Ion Concentration; Membrane Potential, Mitochondrial; Mitochondria; Oxygen; Oxygen Consumption; Platyhelminths; Pyrroles; Reactive Oxygen Species

2013
Reporter dyes demonstrate functional expression of multidrug resistance proteins in the marine flatworm Macrostomum lignano: the sponge-derived dye Ageladine A is not a substrate of these transporters.
    Marine drugs, 2013, Oct-16, Volume: 11, Issue:10

    Topics: Aniline Compounds; Animals; Astrocytes; Biological Transport; Brain; Cells, Cultured; Coloring Agents; Fluoresceins; Fluorescent Dyes; Fura-2; Glutathione; Multidrug Resistance-Associated Proteins; Platyhelminths; Probenecid; Pyrroles; Rats; Rats, Wistar; Rhodamines; Verapamil; Xanthenes

2013
The chemically synthesized ageladine A-derivative LysoGlow84 stains lysosomes in viable mammalian brain cells and specific structures in the marine flatworm Macrostomum lignano.
    Marine drugs, 2015, Feb-11, Volume: 13, Issue:2

    Topics: Animals; Astrocytes; Brain; Cell Survival; Cells, Cultured; Coloring Agents; Fluorescent Dyes; Indicators and Reagents; Lysosomes; Mass Spectrometry; Materials Testing; Microscopy, Confocal; Microscopy, Fluorescence; Platyhelminths; Pyrroles; Rats; Rats, Wistar

2015
One-Pot Evolution of Ageladine A through a Bio-Inspired Cascade towards Selective Modulators of Neuronal Differentiation.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2016, Oct-04, Volume: 22, Issue:41

    Topics: Aniline Compounds; Animals; Biomimetics; Cell Differentiation; Dyrk Kinases; Guanidines; Humans; Imidazoles; Mice; Molecular Structure; Neural Stem Cells; Neurons; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyrroles; Small Molecule Libraries; Structure-Activity Relationship

2016
Enhancement of photosynthesis in Synechococcus bacillaris by sponge-derived Ageladine A.
    PloS one, 2019, Volume: 14, Issue:3

    Topics: Animals; Oxygen; Photosynthesis; Photosystem II Protein Complex; Porifera; Pyrroles; Symbiosis; Synechococcus; Ultraviolet Rays

2019
Sponge-derived Ageladine A affects the in vivo fluorescence emission spectra of microalgae.
    PloS one, 2020, Volume: 15, Issue:11

    Topics: Agelas; Animals; Chlorophyll A; Fluorescence; Micrasterias; Microalgae; Photosynthesis; Phycobilisomes; Phycoerythrin; Pigments, Biological; Pyrroles; Species Specificity; Spectrometry, Fluorescence; Symbiosis; Synechococcus; Ultraviolet Rays

2020
Effects of sponge-derived Ageladine A on the photosynthesis of different microalgal species and strains.
    PloS one, 2020, Volume: 15, Issue:12

    Topics: Agelas; Animals; Microalgae; Photosynthesis; Pyrroles; Symbiosis

2020