Page last updated: 2024-08-18

pyrroles and adenosine diphosphate

pyrroles has been researched along with adenosine diphosphate in 40 studies

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (15.00)	18.7374
1990's	10 (25.00)	18.2507
2000's	19 (47.50)	29.6817
2010's	3 (7.50)	24.3611
2020's	2 (5.00)	2.80

Authors

Authors	Studies
Illiano, S; Nagao, T; Vanhoutte, PM	1
Kurachi, Y; Machulda, MM; Shen, WK; Tung, RT	1
Aspinall, RJ; Dunne, MJ; Petersen, OH	1
Meister, A; Seddon, AP; Zhao, KY	1
Brown, PR; Parks, RE	1
Caldwell, IC; Chu, SY; Henderson, JF; Mikoshiba, A	1
Clement-Metral, JD; Fanica-Gaignier, M	1
Hashimoto, Y; Hoshina, K; Ishimoto, S; Jimba, M; Komoriya, K; Kurozumi, S; Naruchi, T; Ohtsu, A; Wakabayashi, T	1
Ayton, BA; Dunne, MJ; Harding, EA; Jaggar, JH	1
Deutsch, N; Weiss, JN	1
Kamouchi, M; Kitamura, K	1
Ayton, BJ; Dunne, MJ; Harding, EA; Jaggar, JH	1
Morimoto, Y; Oda, M; Yamamoto, N; Yamashita, A; Yokota, K	1
Forrest, CR; He, W; Hopper, R; Neligan, P; Pang, CY; Xu, H; Zhong, A	1
Fein, A; Tertyshnikova, S	1
Altomare, C; Borisova, TN; Carotti, A; Cellamare, S; Summo, L; Varlamov, AV; Voskressensky, LG	1
Conde, M; Porras, T; Rosado, JA; Sage, SO	1
Elcock, AH; Rockey, WM	1
Altomare, C; Borisova, TN; Carotti, A; de Candia, M; Kulikova, LN; Varlamov, AV; Voskressensky, LG	1
ALBERS, RW; FAHN, S; KOVAL, GJ	1
Elisaf, M; Goudevenos, JA; Mitsios, JV; Papathanasiou, AI; Rodis, FI; Tselepis, AD	1
Martus, P; Piorkowski, M; Rauch, U; Schultheiss, HP; Schwimmbeck, PL; Weikert, U	1
Aznar, J; Gabriel, F; Guiral, V; Labiós, M; Martínez, E; Martínez, M	1
Bellia, A; Carnevale, R; Ferro, D; Lauro, R; Lenti, L; Pignatelli, P; Sanguigni, V; Sorge, R; Tesauro, M; Violi, F	1
Inoue, K; Koizumi, S; Nasu-Tada, K	1
Elisaf, M; Goudevenos, JA; Mitsios, JV; Papathanasiou, AI; Tselepis, AD	1
Aherne, GW; Barrie, SE; Boxall, KJ; Garrett, MD; Mittnacht, S; Oliver, AW; Paul, A; Pearl, LH	1
Bianchi, C; Boodhwani, M; Feng, J; Laham, R; Li, J; Mieno, S; Nakai, Y; Ramlawi, B; Sellke, FW; Voisine, P	1
Nisanci, Y; Oflaz, H; Pamukcu, B; Tirnaksiz, E	1
Bestehorn, HP; Büttner, HJ; Frundi, D; Hochholzer, W; Neumann, FJ; Stratz, C; Trenk, D; Valina, CM	1
Auger, KR; Carson, JD; Coales, SJ; Copeland, RA; Dhanak, D; Hamuro, Y; Huang, PS; Jackson, JR; Luo, L; Molnar, KS; Sudakin, V; Sung, CM; Tummino, PJ; Tuske, SJ	1
Fu, E; Gong, R; Sun, Y; Zhong, C	1
Shen, J; Zhang, Q; Zhang, RY	1
Jobson, AG; Lountos, GT; Pommier, Y; Shoemaker, RH; Tropea, JE; Waugh, DS; Zhang, D	1
Borzilleri, R; Burford, N; Chen, Z; Crews, D; Doyle, M; Duke, GJ; Goldfarb, V; Gottardis, M; Kiefer, SE; Kim, K; Kut, S; Lombardo, L; Lu, S; McDonnell, PA; Metzler, W; Newitt, JA; Ortega, M; Roussell, DL; Shen, H; Tao, L; Tarby, C; Vaccaro, W; Yanchunas, J	1
Ak, K; Arsan, S; Eksioglu-Demiralp, E; Iqbal, O; Isbir, S; Tetik, S; Yardimci, T	1
Ahn, JH; Bliden, KP; Gho, EH; Gurbel, PA; Hwang, JY; Hwang, SJ; Jeong, YH; Kim, S; Kwak, CH; Kwon, TJ; Park, JR; Park, Y; Tantry, US	1
Chu, LX; He, LP; Liang, ZS; Mo, CG; Qin, YQ; Wang, XD; Xie, J; Yang, F; Zhou, SX	1
Aoyama, Y; Asakai, R; Kamei, Y; Koushi, M	1
Goto, M; Igarashi, Y; Imura, T; Inagaki, A	1

Trials

8 trial(s) available for pyrroles and adenosine diphosphate

Article	Year
Atorvastatin does not affect the antiplatelet potency of clopidogrel when it is administered concomitantly for 5 weeks in patients with acute coronary syndromes. Circulation, 2004, Mar-23, Volume: 109, Issue:11 Topics: Acute Disease; Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Atorvastatin; CD40 Ligand; Clopidogrel; Combined Modality Therapy; Coronary Disease; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Administration Schedule; Drug Interactions; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inactivation, Metabolic; Male; Middle Aged; P-Selectin; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Pravastatin; Pyrroles; Stents; Ticlopidine; Treatment Outcome	2004
ADP induced platelet degranulation in healthy individuals is reduced by clopidogrel after pretreatment with atorvastatin. Thrombosis and haemostasis, 2004, Volume: 92, Issue:3 Topics: Adenosine Diphosphate; Adolescent; Adult; Atorvastatin; Cell Degranulation; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Fibrinogen; Heptanoic Acids; Humans; Middle Aged; P-Selectin; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Pyrroles; Ticlopidine	2004
Short-term treatment with atorvastatin reduces platelet CD40 ligand and thrombin generation in hypercholesterolemic patients. Circulation, 2005, Feb-01, Volume: 111, Issue:4 Topics: Adenosine Diphosphate; Atorvastatin; Biomarkers; Blood Coagulation; Blood Platelets; CD40 Ligand; Collagen; Coronary Disease; Female; Fibrinolytic Agents; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Monocytes; Multifactorial Inheritance; Peptide Fragments; Prothrombin; Pyrroles; Solubility; Thrombin; Thromboplastin; Treatment Outcome	2005
Effect of high dose statin therapy on platelet function; statins reduce aspirin-resistant platelet aggregation in patients with coronary heart disease. Journal of thrombosis and thrombolysis, 2009, Volume: 27, Issue:1 Topics: Adenosine Diphosphate; Adult; Aged; Aspirin; Atorvastatin; Cholesterol, HDL; Cholesterol, LDL; Collagen; Coronary Disease; Diabetes Complications; Drug Resistance; Epinephrine; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Male; Middle Aged; Platelet Aggregation; Platelet Function Tests; Pyrroles; Smoking	2009
Impact of cytochrome P450 3A4-metabolized statins on the antiplatelet effect of a 600-mg loading dose clopidogrel and on clinical outcome in patients undergoing elective coronary stent placement. Thrombosis and haemostasis, 2008, Volume: 99, Issue:1 Topics: Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Atorvastatin; Blood Platelets; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Coronary Disease; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Female; Flow Cytometry; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kaplan-Meier Estimate; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Pyrroles; Simvastatin; Stents; Ticlopidine; Time Factors; Treatment Outcome	2008
[Impact of statins on clopidogrel platelet inhibition in patients with acute coronary syndrome or stable angina]. Zhonghua xin xue guan bing za zhi, 2008, Volume: 36, Issue:9 Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Aged; Angina Pectoris; Atorvastatin; Clopidogrel; Drug Interactions; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Pravastatin; Prospective Studies; Pyrroles; Ticlopidine	2008
Clopidogrel provides significantly greater inhibition of platelet activity than aspirin when combined with atorvastatin after coronary artery bypass grafting: a prospective randomized study. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2010, Volume: 16, Issue:2 Topics: Adenosine Diphosphate; Aged; Aspirin; Atorvastatin; Clopidogrel; Comorbidity; Coronary Artery Bypass; Coronary Disease; Drug Therapy, Combination; Female; Fibrinogen; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Lipoproteins, LDL; Male; Middle Aged; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Postoperative Complications; Prospective Studies; Pyrroles; Ticlopidine	2010
Accelerated platelet inhibition by switching from atorvastatin to a non-CYP3A4-metabolized statin in patients with high platelet reactivity (ACCEL-STATIN) study. European heart journal, 2012, Volume: 33, Issue:17 Topics: Adenosine Diphosphate; Aspirin; Atorvastatin; Calcium Channel Blockers; Clopidogrel; Coronary Artery Disease; Cytochrome P-450 CYP3A; Drug Substitution; Drug Therapy, Combination; Female; Fluorobenzenes; Genotype; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Percutaneous Coronary Intervention; Platelet Aggregation; Platelet Aggregation Inhibitors; Pravastatin; Prospective Studies; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Sulfonamides; Ticlopidine	2012

Other Studies

32 other study(ies) available for pyrroles and adenosine diphosphate

Article	Year
Calmidazolium, a calmodulin inhibitor, inhibits endothelium-dependent relaxations resistant to nitro-L-arginine in the canine coronary artery. British journal of pharmacology, 1992, Volume: 107, Issue:2 Topics: Adenosine Diphosphate; Adrenergic beta-Antagonists; Animals; Arginine; Benzopyrans; Bradykinin; Calcimycin; Calmodulin; Coronary Vessels; Cromakalim; Dogs; Endothelium, Vascular; Ethanolamines; Imidazoles; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Nebivolol; Nitric Oxide; Nitroarginine; Pyrroles; Vasodilator Agents	1992
Essential role of nucleotide diphosphates in nicorandil-mediated activation of cardiac ATP-sensitive K+ channel. A comparison with pinacidil and lemakalim. Circulation research, 1991, Volume: 69, Issue:4 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Guanidines; Myocardium; Niacinamide; Nicorandil; Phosphorylation; Pinacidil; Potassium Channels; Pyrroles; Vasodilator Agents	1991
The effects of cromakalim on ATP-sensitive potassium channels in insulin-secreting cells. British journal of pharmacology, 1990, Volume: 99, Issue:1 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Benzopyrans; Cell Line; Cromakalim; Diazoxide; Insulin; Insulin Secretion; Islets of Langerhans; Potassium Channels; Potassium Radioisotopes; Pyrroles; Rubidium Radioisotopes; Sodium	1990
Activation of glutamate by gamma-glutamate kinase: formation of gamma-cis-cycloglutamyl phosphate, an analog of gamma-glutamyl phosphate. The Journal of biological chemistry, 1989, Jul-05, Volume: 264, Issue:19 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aldehyde Oxidoreductases; Chromatography, High Pressure Liquid; Drug Stability; Escherichia coli; Glutamate-5-Semialdehyde Dehydrogenase; Glutamates; Glutamic Acid; Hydroxamic Acids; Kinetics; Molecular Conformation; NADP; Organophosphorus Compounds; Phosphates; Phosphotransferases; Phosphotransferases (Carboxyl Group Acceptor); Pyrroles; Pyrrolidonecarboxylic Acid	1989
Incorporation of nucleosides into the nucleotide pools of human erythrocytes. Adenosine and its analogs. Biochemistry, 1973, Aug-14, Volume: 12, Issue:17 Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aminohydrolases; Antibiotics, Antineoplastic; Aza Compounds; Carbohydrate Metabolism; Deoxyadenosines; Erythrocytes; Fluorine; Humans; Inosine; Mercaptopurine; Nucleosides; Phosphotransferases; Pyrazoles; Pyrimidines; Pyrimidinones; Pyrroles; Ribonucleosides; Structure-Activity Relationship	1973
Kinetic studies of adenosine kinase from Ehrlich ascites tumor cells. The Journal of biological chemistry, 1972, Apr-10, Volume: 247, Issue:7 Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Binding Sites; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Feedback; Kinetics; Mercaptopurine; Phosphotransferases; Protein Binding; Pyrimidines; Pyrroles; Ribonucleosides; Ribonucleotides; Structure-Activity Relationship	1972
ATP inhibition of aminolevulinate (ALA) synthetase activity in Rhodopseudomonas spheroides Y. Biochemical and biophysical research communications, 1971, Jul-02, Volume: 44, Issue:1 Topics: Acyltransferases; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Ammonium Sulfate; Chemical Precipitation; Chlorophyll; Chromatography, Gel; Chromatography, Ion Exchange; Coenzyme A; Glycine; Iron; Levulinic Acids; Pyrroles; Rhodopseudomonas; Succinates	1971
Inhibition of platelet aggregation by novel benzoylpyrrole derivatives. Advances in prostaglandin and thromboxane research, 1980, Volume: 6 Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Biological Assay; Blood Platelets; Cattle; Collagen; Epinephrine; Humans; Indomethacin; Male; Platelet Aggregation; Prostaglandin Endoperoxides; Pyrroles; Rabbits; Rats	1980
Activation of potassium channels by diazoxide and cromakalim in insulin-secreting cells is dependent upon internal ADP and channel run-down. Biochemical Society transactions, 1993, Volume: 21, Issue:4 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Benzopyrans; Cell Line; Cromakalim; Diazoxide; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Kinetics; Pancreatic Neoplasms; Potassium Channels; Pyrroles; Tumor Cells, Cultured	1993
Effects of trypsin on cardiac ATP-sensitive K+ channels. The American journal of physiology, 1994, Volume: 266, Issue:2 Pt 2 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Benzopyrans; Cells, Cultured; Cromakalim; Female; Glyburide; Glyoxal; Guinea Pigs; Heart; Magnesium; Male; Membrane Potentials; Phenylglyoxal; Potassium Channels; Pyrroles; Trypsin	1994
Regulation of ATP-sensitive K+ channels by ATP and nucleotide diphosphate in rabbit portal vein. The American journal of physiology, 1994, Volume: 266, Issue:5 Pt 2 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Egtazic Acid; Guanidines; In Vitro Techniques; Ion Channel Gating; Magnesium; Male; Membrane Potentials; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Pinacidil; Portal Vein; Potassium Channels; Probability; Pyrroles; Rabbits; Ribonucleotides; Time Factors; Vasodilator Agents	1994
Interaction of diazoxide and cromakalim with ATP-regulated K+ channels in rodent and clonal insulin-secreting cells. Journal of molecular endocrinology, 1993, Volume: 10, Issue:1 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Benzopyrans; Cells, Cultured; Cromakalim; Diazoxide; Insulin; Insulin Secretion; Islets of Langerhans; Models, Biological; Potassium Channels; Pyrroles; Rats	1993
Effect of KBT-3022, a new diphenylthiazole derivative, on platelet functions. The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:9 Topics: Adenosine Diphosphate; Administration, Oral; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Collagen; Edema; Erythema; Gastric Mucosa; Guinea Pigs; Humans; Mice; Platelet Aggregation Inhibitors; Pyrroles; Rabbits; Rats; Serotonin; Species Specificity; Thiazoles; Thrombin; Ultraviolet Rays	1995
Role of ATP-sensitive K+ channels in ischemic preconditioning of skeletal muscle against infarction. The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 2 Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Energy Metabolism; Hypoxanthine; Infarction; Ischemic Preconditioning; Muscle, Skeletal; Phosphocreatine; Potassium Channels; Pyrroles; Reperfusion; Surgical Flaps; Swine; Vasodilator Agents; Xanthine; Xanthines	1997
Inhibition of inositol 1,4,5-trisphosphate-induced Ca2+ release by cAMP-dependent protein kinase in a living cell. Proceedings of the National Academy of Sciences of the United States of America, 1998, Feb-17, Volume: 95, Issue:4 Topics: Adenosine Diphosphate; Animals; Calcium; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoplasm; Enzyme Inhibitors; Epoprostenol; Indoles; Inositol 1,4,5-Trisphosphate; Megakaryocytes; Platelet Aggregation Inhibitors; Pyrroles; Rats; Rats, Wistar	1998
Pyrrolo[3,2-c]pyridine derivatives as inhibitors of platelet aggregation. Bioorganic & medicinal chemistry letters, 2000, Mar-20, Volume: 10, Issue:6 Topics: Adenosine Diphosphate; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Humans; In Vitro Techniques; Lipids; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridines; Pyrroles; Structure-Activity Relationship; Ticlopidine	2000
Cyclic nucleotides modulate store-mediated calcium entry through the activation of protein-tyrosine phosphatases and altered actin polymerization in human platelets. The Journal of biological chemistry, 2001, May-11, Volume: 276, Issue:19 Topics: Actins; Adenosine Diphosphate; Alprostadil; Arsenicals; Blood Platelets; Calcium; Carbazoles; Cyclic AMP; Cyclic GMP; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Humans; In Vitro Techniques; Indoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitroprusside; Phosphorylation; Platelet Activation; Platelet Aggregation Inhibitors; Protein Tyrosine Phosphatases; Pyrroles; Thapsigargin; Thrombin; Vanadates	2001
Progress toward virtual screening for drug side effects. Proteins, 2002, Sep-01, Volume: 48, Issue:4 Topics: Adenosine Diphosphate; Algorithms; Azepines; Benzamides; Binding Sites; Computational Biology; Computer Simulation; Drug Delivery Systems; Enzyme Inhibitors; Guanosine Diphosphate; Imatinib Mesylate; Models, Molecular; Piperazines; Protein Binding; Protein Kinases; Pyrimidines; Pyrroles; Receptors, Drug; Receptors, Purinergic P2; Sensitivity and Specificity; Static Electricity	2002
Investigation on the antiplatelet activity of pyrrolo[3,2-c]pyridine-containing compounds. The Journal of pharmacy and pharmacology, 2003, Volume: 55, Issue:3 Topics: Adenosine Diphosphate; Adult; Chemical Phenomena; Chemistry, Physical; Dose-Response Relationship, Drug; Epinephrine; Humans; In Vitro Techniques; Indicators and Reagents; Magnetic Resonance Spectroscopy; Middle Aged; Nephelometry and Turbidimetry; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridines; Pyrroles; Structure-Activity Relationship	2003
ELECTROPHORUS ADENOSINE TRIPHOSPHATASE: SODIUM-ACTIVATED EXCHANGE AFTER N-ETHYLALEIMIDE TREATMENT. Science (New York, N.Y.), 1964, Jul-17, Volume: 145, Issue:3629 Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Chlorides; Eels; Electric Organ; Electrophorus; Ions; Lithium; Magnesium; Microsomes; Pharmacology; Potassium; Pyrroles; Research; Sodium; Sodium Chloride	1964
Effect of atorvastatin upon platelet activation in hypercholesterolemia, evaluated by flow cytometry. Thrombosis research, 2005, Volume: 115, Issue:4 Topics: Adenosine Diphosphate; Adult; Aged; Atorvastatin; Blood Platelets; Case-Control Studies; Cholesterol; Cholesterol, LDL; Female; Flow Cytometry; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; In Vitro Techniques; Male; Middle Aged; P-Selectin; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrroles; Risk Factors; Thrombin; Thrombosis	2005
Involvement of beta1 integrin in microglial chemotaxis and proliferation on fibronectin: different regulations by ADP through PKA. Glia, 2005, Nov-01, Volume: 52, Issue:2 Topics: Adenosine Diphosphate; Animals; Carbazoles; Cell Membrane; Cell Proliferation; Cell Separation; Cells, Cultured; Chemotaxis; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Fibronectins; Fluorescent Antibody Technique; Immunohistochemistry; Indoles; Integrin beta1; Membrane Proteins; Microglia; Pyrroles; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y12	2005
The inhibitory potency of clopidogrel on ADP-induced platelet activation is not attenuated when it is co-administered with atorvastatin (20 mg/day) for 5 weeks in patients with acute coronary syndromes. Platelets, 2005, Volume: 16, Issue:5 Topics: Acute Disease; Adenosine Diphosphate; Aged; Angioplasty, Balloon, Coronary; Anticholesteremic Agents; Atorvastatin; Blood Platelets; CD40 Ligand; Cholesterol; Cholesterol, LDL; Clopidogrel; Coronary Disease; Drug Administration Schedule; Drug Interactions; Female; Flow Cytometry; Heptanoic Acids; Humans; Male; Middle Aged; P-Selectin; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrroles; Ticlopidine; Triglycerides	2005
Trans-activation of the DNA-damage signalling protein kinase Chk2 by T-loop exchange. The EMBO journal, 2006, Jul-12, Volume: 25, Issue:13 Topics: Adenosine Diphosphate; Ataxia Telangiectasia Mutated Proteins; Azepines; Catalytic Domain; Cell Cycle Proteins; Checkpoint Kinase 2; Dimerization; DNA Damage; DNA-Binding Proteins; Enzyme Activation; Humans; Models, Molecular; Phosphorylation; Protein Conformation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Pyrroles; Signal Transduction; Trans-Activators; Tumor Suppressor Proteins	2006
High-dose atorvastatin improves hypercholesterolemic coronary endothelial dysfunction without improving the angiogenic response. Circulation, 2006, Jul-04, Volume: 114, Issue:1 Suppl Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Angiostatins; Animals; Apoptosis; Apoptosis Inducing Factor; Arterioles; Atorvastatin; Caspase 3; Caspases; Cholesterol; Coronary Circulation; Coronary Vessels; Drug Evaluation, Preclinical; Endostatins; Endothelium, Vascular; Female; Fibroblast Growth Factor 2; Gene Expression Regulation; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Matrix Metalloproteinase 9; Myocardial Ischemia; Neovascularization, Physiologic; Nitric Oxide; Nitric Oxide Synthase Type III; Nitroprusside; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Receptor, TIE-2; Swine; Swine, Miniature; Vascular Endothelial Growth Factor A; Vasodilation	2006
Conformation-dependent ligand regulation of ATP hydrolysis by human KSP: activation of basal hydrolysis and inhibition of microtubule-stimulated hydrolysis by a single, small molecule modulator. Journal of the American Chemical Society, 2008, Jun-18, Volume: 130, Issue:24 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Binding, Competitive; Cell Line; Cell Proliferation; Deuterium; Humans; Hydrocarbons, Fluorinated; Hydrogen; Hydrolysis; Kinesins; Ligands; Maleates; Microtubules; Pyrroles; Spindle Apparatus	2008
A highly selective fluorescent probe for pyrophosphate in aqueous solution. Organic & biomolecular chemistry, 2008, Sep-07, Volume: 6, Issue:17 Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Biosensing Techniques; Diphosphates; Fluorescent Dyes; Guanidine; Models, Molecular; Molecular Probes; Pyrroles; Solutions; Water	2008
Crystal structure of checkpoint kinase 2 in complex with NSC 109555, a potent and selective inhibitor. Protein science : a publication of the Protein Society, 2009, Volume: 18, Issue:1 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Azepines; Carbanilides; Catalytic Domain; Checkpoint Kinase 2; Crystallography, X-Ray; Drug Design; Humans; Models, Molecular; Protein Binding; Protein Serine-Threonine Kinases; Pyrroles; Structure-Activity Relationship; Substrate Specificity	2009
Assessing compound binding to the Eg5 motor domain using a thermal shift assay. Analytical biochemistry, 2009, Sep-01, Volume: 392, Issue:1 Topics: Adenosine Diphosphate; Biochemistry; Biophysical Phenomena; Calorimetry; Cell Line, Tumor; Circular Dichroism; Humans; Kinesins; Magnetic Resonance Spectroscopy; Models, Molecular; Protein Binding; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Pyrroles; Temperature; Triazines	2009
Pravastatin and C reactive protein modulate protease- activated receptor-1 expression in vitro blood platelets. Cellular and molecular biology (Noisy-le-Grand, France), 2016, Feb-29, Volume: 62, Issue:2 Topics: Adenosine Diphosphate; Blood Platelets; C-Reactive Protein; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gene Expression Regulation; Humans; Immunoblotting; P-Selectin; Platelet Aggregation; Pravastatin; Pyrroles; Quinazolines; Receptor, PAR-1; Receptors, Thromboxane A2, Prostaglandin H2; Scavenger Receptors, Class E; Thrombin	2016
Bisindolylpyrrole triggers transient mitochondrial permeability transitions to cause apoptosis in a VDAC1/2 and cyclophilin D-dependent manner via the ANT-associated pore. Scientific reports, 2020, 10-12, Volume: 10, Issue:1 Topics: Adenosine Diphosphate; Animals; Apoptosis; Calcium; Cytoprotection; Gene Knockdown Techniques; HeLa Cells; Humans; Mitochondria, Liver; Mitochondrial ADP, ATP Translocases; Mitochondrial Transmembrane Permeability-Driven Necrosis; Peptidyl-Prolyl Isomerase F; Protein Kinase C; Pyrroles; Rats; RNA, Small Interfering; Voltage-Dependent Anion Channel 1; Voltage-Dependent Anion Channel 2	2020
Optimization of dye solutions for detecting damaged pancreatic tissues during islet isolation procedures. PloS one, 2021, Volume: 16, Issue:8 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coloring Agents; DNA; Glucose; Humans; Indigo Carmine; Insulin; Islets of Langerhans; Pancreas; Phenols; Pyrroles; Swine	2021