pyrroles has been researched along with acetylcysteine in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 16 (50.00) | 29.6817 |
| 2010's | 14 (43.75) | 24.3611 |
| 2020's | 2 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Baillie, TA; Davis, MR; Doss, G; Kari, PH; Vyas, KP; Zhang, KE | 1 |
| Green, MP; Hayes, CJ; Prodger, JC; Sherlock, AE | 1 |
| Aravamudan, B; Broadie, K | 1 |
| Hoff, HF; Hoppe, G; O'Neil, J; Salomon, RL; Wu, Z | 1 |
| Liu, J; Sayre, LM; Xu, G; Yuan, Q; Zhang, WH | 1 |
| Diehl, JF; Dimmeler, S; Haendeler, J; Hoffmann, J; Spyridopoulos, I; Vasa, M; Zeiher, AM | 1 |
| Li, L; Renier, G; Sawamura, T | 1 |
| Baer, BR; Henne, KR; Rettie, AE | 1 |
| Mahendran, R; Pook, SH; Toh, CK | 1 |
| Bowen, EG; Wardrop, DJ | 1 |
| Demura, Y; Scerbavicius, R; Taraseviciene-Stewart, L; Tuder, RM; Voelkel, NF | 1 |
| Bacon, KB; Benet-Buchholz, J; Bitzer, J; Gantner, F; Mayer-Bartschmid, A; Müller, H; Reinemer, P; Stadler, M; Tichy, HV | 1 |
| Fukuda, N; Kanai, M; Shibasaki, M | 1 |
| Chen, P; Edwards, PA; Guo, AM; Scicli, AG; Trick, G | 1 |
| Lóopez-Marure, R; Massó, FA; Montaño, LF; Páez, A; Rodríguez, E; Sánchez, CA; Varela, E; Zapata, E | 1 |
| Tsukamoto, S; Yokosawa, H | 1 |
| Amato, M; Bellandi, F; Gallopin, M; Leoncini, M; Maioli, M; Manzone, C; Micheletti, C; Tedeschi, D; Toso, A | 1 |
| Alemdar, R; Aydin, M; Basar, C; Caglar, O; Erden, I; Ordu, S; Ozhan, H; Yalcin, S | 1 |
| Biswas, D; Biswas, T; Sarkar, A; Sen, G | 1 |
| Lu, D; Peterson, LA; Phillips, MB; Sullivan, MM | 1 |
| Bianco, A; Briguori, C; Colombo, A; Condorelli, G; De Micco, F; Donnarumma, E; Fiore, D; Focaccio, A; Golia, B; Quintavalle, C; Ricciardelli, B; Troncone, G; Visconti, G; Zabatta, MA | 1 |
| Cai, DQ; Kim, CS; Kim, DH; Kim, SK; Lee, KJ; Qi, XF; Qin, JW; Wu, Z; Yu, YH; Zheng, L | 1 |
| Brodsky, SV; Hebert, LA; Ivanov, I; Muni, N; Nadasdy, G; Nadasdy, T; Rovin, BH; Satoskar, AA; Vance, JC; Ware, KM | 1 |
| Andrade, V; Batoréu, MC; dos Santos, AP; Gonçalves, LL; Mateus, ML; Torres, ME | 1 |
| Inoue, M; Nagatomo, M; Yoshioka, S | 1 |
| Butini, S; Campiani, G; Lennon, JC; O'Meara, A; Williams, DC; Zisterer, DM | 1 |
| Chung, MH; Hahm, KB; Han, YM; Jeong, M; Ko, KH; Kwon, CI; Park, JM | 1 |
| Fu, PP; He, X; Ma, L; Xia, Q | 1 |
| Nagatomo, M | 1 |
| Guo, X; Han, L; Jia, Y; Li, W; Peng, Y; Zhang, Z; Zhao, Y; Zheng, J | 1 |
| Braitberg, G; Hodgson, SE; Koutsogiannis, Z; Stanley, B; Sulaeman, SJ | 1 |
| Ciesielska, K; Muńko, M; Pluskota-Karwatka, D | 1 |
3 review(s) available for pyrroles and acetylcysteine
| Article | Year |
|---|---|
Total synthesis of lactacystin and salinosporamide A.
Topics: Acetylcysteine; Enzyme Inhibitors; Lactones; Molecular Structure; Proteasome Inhibitors; Pyrroles; Stereoisomerism | 2007 |
Targeting the proteasome pathway.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Biological Products; Boronic Acids; Bortezomib; Drug Delivery Systems; Drug Discovery; Humans; Lactones; Neoplasms; Peptides; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Pyrroles; Structure-Activity Relationship; Ubiquitin; Ubiquitin-Activating Enzymes; Ubiquitins | 2009 |
[Development of Synthetic Strategies for Densely Oxygenated Natural Products: Total Synthesis of Lactacystin and Zaragozic Acid C Using Photochemical C(sp
Topics: Acetylcysteine; Acylation; Alkylation; Biological Products; Bridged Bicyclo Compounds, Heterocyclic; Carbon; Enzyme Inhibitors; Farnesyl-Diphosphate Farnesyltransferase; Free Radicals; Gluconates; Lactones; Oxidation-Reduction; Oxygen; Photochemical Processes; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrroles; Stereoisomerism | 2019 |
3 trial(s) available for pyrroles and acetylcysteine
| Article | Year |
|---|---|
Usefulness of atorvastatin (80 mg) in prevention of contrast-induced nephropathy in patients with chronic renal disease.
Topics: Acetylcysteine; Acute Kidney Injury; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticholesteremic Agents; Atorvastatin; Biomarkers; Contrast Media; Coronary Angiography; Creatinine; Female; Fluid Therapy; Heptanoic Acids; Humans; Male; Prospective Studies; Pyrroles; Renal Insufficiency, Chronic; Risk Factors | 2010 |
Efficacy of short-term high-dose atorvastatin for prevention of contrast-induced nephropathy in patients undergoing coronary angiography.
Topics: Acetylcysteine; Acute Kidney Injury; Adult; Atorvastatin; Contrast Media; Coronary Angiography; Creatinine; Female; Glomerular Filtration Rate; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Pyrroles | 2010 |
Impact of a high loading dose of atorvastatin on contrast-induced acute kidney injury.
Topics: Acetylcysteine; Acute Kidney Injury; Aged; Animals; Atorvastatin; Cells, Cultured; Contrast Media; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; JNK Mitogen-Activated Protein Kinases; Male; Middle Aged; Pyrroles; Tumor Suppressor Protein p53 | 2012 |
26 other study(ies) available for pyrroles and acetylcysteine
| Article | Year |
|---|---|
Metabolism of A dopamine D(4)-selective antagonist in rat, monkey, and humans: formation of A novel mercapturic acid adduct.
Topics: Acetylcysteine; Animals; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Humans; Macaca mulatta; Male; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D4 | 2000 |
A convenient method for 3-pyrroline synthesis.
Topics: Acetylcysteine; Alkylation; Anti-Bacterial Agents; Combinatorial Chemistry Techniques; Cyclization; Lactams; Pyrroles; Stereoisomerism | 2001 |
Synaptic Drosophila UNC-13 is regulated by antagonistic G-protein pathways via a proteasome-dependent degradation mechanism.
Topics: Acetylcysteine; Animals; Antibodies; Blotting, Western; Caenorhabditis elegans Proteins; Carbazoles; Carrier Proteins; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cysteine Endopeptidases; Drosophila; Drosophila Proteins; Drug Interactions; Enzyme Inhibitors; Estrenes; GTP-Binding Proteins; Helminth Proteins; Horseradish Peroxidase; Immunohistochemistry; Indoles; Insect Proteins; Maleimides; Microscopy, Confocal; Multienzyme Complexes; Mutation; Neomycin; Neuromuscular Junction; Oligopeptides; Phorbol Esters; Phospholipid Ethers; Presynaptic Terminals; Proteasome Endopeptidase Complex; Pyrroles; Pyrrolidinones; Synapses; Tumor Suppressor Proteins; Type C Phospholipases | 2003 |
Phospholipid hydroxyalkenals: biological and chemical properties of specific oxidized lipids present in atherosclerotic lesions.
Topics: Acetylcysteine; Aldehydes; Animals; Arteriosclerosis; Biological Transport; Cathepsin B; Cholesterol Esters; Chromatography, Liquid; Humans; Intracellular Membranes; Lipoproteins, LDL; Lysine; Lysosomes; Macrophages, Peritoneal; Mice; Oxidation-Reduction; Phosphatidylcholines; Phospholipids; Pyrroles; Spectrometry, Mass, Electrospray Ionization | 2003 |
Model studies on protein side chain modification by 4-oxo-2-nonenal.
Topics: Acetylcysteine; Aldehydes; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Histidine; Imidazoles; Linoleic Acid; Lysine; Magnetic Resonance Spectroscopy; Oxygen; Proteins; Pyrroles; Ribonucleases; Stereoisomerism; Structure-Activity Relationship | 2003 |
Antioxidants inhibit nuclear export of telomerase reverse transcriptase and delay replicative senescence of endothelial cells.
Topics: Acetylcysteine; Antioxidants; Atorvastatin; Cell Nucleus; Cells, Cultured; Cellular Senescence; Depression, Chemical; DNA Replication; DNA-Binding Proteins; DNA, Mitochondrial; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; Heptanoic Acids; Humans; Hydrogen Peroxide; Oxidation-Reduction; Oxidative Stress; Protein Transport; Pyrimidines; Pyrroles; Reactive Oxygen Species; src-Family Kinases; Telomerase | 2004 |
Glucose enhances human macrophage LOX-1 expression: role for LOX-1 in glucose-induced macrophage foam cell formation.
Topics: Acetylcysteine; Adult; Aged; Anti-Infective Agents; Antioxidants; Arteriosclerosis; Cells, Cultured; Curcumin; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Female; Flavonoids; Foam Cells; Gene Expression Regulation; Glucose; Glycation End Products, Advanced; Humans; Hyperglycemia; Macrophages; Male; MAP Kinase Signaling System; Mesylates; Middle Aged; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NF-kappa B; Nitriles; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Protein Processing, Post-Translational; Pyrroles; Receptors, LDL; RNA, Messenger; Signal Transduction; Sulfones; Transcription Factor AP-1; Tumor Necrosis Factor-alpha | 2004 |
Bioactivation of 4-ipomeanol by CYP4B1: adduct characterization and evidence for an enedial intermediate.
Topics: Acetylcysteine; Aldehydes; Animals; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 Enzyme System; Glutathione; Humans; Liver; Lung; Lysine; NADP; Pyrroles; Rabbits; Spectrometry, Mass, Electrospray Ionization; Terpenes | 2005 |
Combination of thiol antioxidant Silibinin with Brostallicin is associated with increase in the anti-apoptotic protein Bcl-2 and decrease in caspase 3 activity.
Topics: Acetylcysteine; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspases; Cell Line, Tumor; Down-Regulation; Drug Antagonism; Drug Screening Assays, Antitumor; Enzyme Activation; Guanidines; Humans; Nasopharyngeal Neoplasms; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Signal Transduction; Silybin; Silymarin; Sulfhydryl Compounds; Up-Regulation | 2006 |
A formal synthesis of (+)-lactacystin.
Topics: Acetylcysteine; Alkylation; Hydrocarbons; Methane; Molecular Structure; Pyrroles | 2005 |
N-acetylcysteine treatment protects against VEGF-receptor blockade-related emphysema.
Topics: Acetylcysteine; Animals; Apoptosis; Disease Models, Animal; Dose-Response Relationship, Drug; Emphysema; Heme Oxygenase-1; Hypertrophy, Right Ventricular; Indoles; Lung; Male; Oxidative Stress; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Vascular Endothelial Growth Factor | 2004 |
Cinnabaramides A-G: analogues of lactacystin and salinosporamide from a terrestrial streptomycete.
Topics: Acetylcysteine; Crystallography, X-Ray; Humans; Lactones; Molecular Conformation; Molecular Structure; Proteasome Inhibitors; Pyrroles; Streptomyces | 2007 |
Role of NADPH oxidase and ANG II in diabetes-induced retinal leukostasis.
Topics: Acetophenones; Acetylcysteine; Angiogenesis Inhibitors; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Imidazoles; Indoles; Leukostasis; Losartan; Male; NADPH Oxidases; Pyridines; Pyrroles; Rats; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Retinal Diseases; Vascular Endothelial Growth Factor A; Vasoconstrictor Agents | 2007 |
Statin-induced inhibition of MCF-7 breast cancer cell proliferation is related to cell cycle arrest and apoptotic and necrotic cell death mediated by an enhanced oxidative stress.
Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis; Atorvastatin; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Membrane; Cell Proliferation; DNA Replication; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Membrane Potential, Mitochondrial; Necrosis; Oxidative Stress; Pyrroles; Reactive Oxygen Species; Simvastatin | 2008 |
Atorvastatin acts synergistically with N-acetyl cysteine to provide therapeutic advantage against Fas-activated erythrocyte apoptosis during chronic arsenic exposure in rats.
Topics: Acetylcysteine; Animals; Anticholesteremic Agents; Apoptosis; Arsenic; Arsenic Poisoning; Atorvastatin; Cell Membrane; Drug Synergism; Environmental Pollutants; Erythrocytes; fas Receptor; Free Radical Scavengers; Glutathione; Heptanoic Acids; Male; Oxidative Stress; Pyrroles; Rats; Rats, Sprague-Dawley; Signal Transduction | 2011 |
Polyamines are traps for reactive intermediates in furan metabolism.
Topics: Acetylcysteine; Aldehydes; Animals; Biotransformation; Carcinogens; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Environmental Pollution; Furans; Glutamine; Glutathione; Hepatocytes; Humans; Liver; Lysine; Mass Spectrometry; Ornithine; Oxidation-Reduction; Putrescine; Pyrroles; Rats; Spermidine | 2011 |
HMG-CoA reductase inhibitors induce apoptosis of lymphoma cells by promoting ROS generation and regulating Akt, Erk and p38 signals via suppression of mevalonate pathway.
Topics: Acetylcysteine; Acyl Coenzyme A; Animals; Antioxidants; Apoptosis; Atorvastatin; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; DNA Fragmentation; Extracellular Signal-Regulated MAP Kinases; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lymphoma; Membrane Potential, Mitochondrial; Mevalonic Acid; Mice; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Reactive Oxygen Species; Signal Transduction; Simvastatin | 2013 |
Oral warfarin and the thrombin inhibitor dabigatran increase blood pressure in rats: hidden danger of anticoagulants?
Topics: Acetylcysteine; Animals; Anticoagulants; Antifibrinolytic Agents; Antithrombins; Benzimidazoles; beta-Alanine; Blood Pressure; Dabigatran; Disease Models, Animal; Dose-Response Relationship, Drug; Free Radical Scavengers; Nephrectomy; Pyrroles; Quinazolines; Rats; Receptor, PAR-1; Renal Insufficiency, Chronic; Vitamin K; Warfarin | 2015 |
Role of N-acetylcysteine in protecting against 2,5-hexanedione neurotoxicity in a rat model: changes in urinary pyrroles levels and motor activity performance.
Topics: Acetylcysteine; Animals; Chromatography, Liquid; Hexanones; Male; Motor Activity; Neuroprotective Agents; Neurotoxins; Norleucine; Pyrroles; Rats; Rats, Wistar; Tandem Mass Spectrometry | 2014 |
Application of two direct C(sp3)-H functionalizations for total synthesis of (+)-lactacystin.
Topics: Acetylcysteine; Acylation; Biological Products; Molecular Structure; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrroles; Stereoisomerism | 2015 |
Involvement of AMP-activated protein kinase in mediating pyrrolo-1,5-benzoxazepine-induced apoptosis in neuroblastoma cells.
Topics: Acetyl-CoA Carboxylase; Acetylcysteine; AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Carboplatin; Cell Line, Tumor; Female; Humans; Mechanistic Target of Rapamycin Complex 1; Mice, Inbred BALB C; Mice, Nude; Myeloid Cell Leukemia Sequence 1 Protein; Neuroblastoma; Oxazepines; Phosphorylation; Pyrroles; Reactive Oxygen Species; Tubulin Modulators; Tumor Burden | 2016 |
Synthetic 8-hydroxydeoxyguanosine inhibited metastasis of pancreatic cancer through concerted inhibitions of ERM and Rho-GTPase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Claudin-1; Deoxyguanosine; DNA-Binding Proteins; Epithelial-Mesenchymal Transition; Focal Adhesion Kinase 1; Gene Expression Regulation, Neoplastic; GTPase-Activating Proteins; Humans; Hyaluronan Receptors; Imidazoles; Lung Neoplasms; Matrix Metalloproteinases; Mice; Mice, Nude; NADPH Oxidases; Pancreatic Neoplasms; Pyrroles; rho-Associated Kinases; Signal Transduction; Transcription Factors; Vimentin; Xenograft Model Antitumor Assays; Zonula Occludens-1 Protein | 2017 |
7-N-Acetylcysteine-pyrrole conjugate-A potent DNA reactive metabolite of pyrrolizidine alkaloids.
Topics: Acetylcysteine; Animals; DNA; Humans; Pyrroles; Pyrrolizidine Alkaloids; Rats; Rats, Inbred F344 | 2016 |
Metabolic Activation of Tofacitinib Mediated by Myeloperoxidase
Topics: Acetylcysteine; Activation, Metabolic; Animals; Antirheumatic Agents; Hypochlorous Acid; Leukocytes; Leukopenia; Peroxidase; Piperidines; Pyrimidines; Pyrroles; Rats, Sprague-Dawley | 2019 |
Toceranib: Isolated acute liver injury following ingestion of a canine tyrosine kinase inhibitor treated with N-acetylcysteine.
Topics: Acetylcysteine; Animals; Dogs; Eating; Humans; Liver; Protein Kinase Inhibitors; Pyrroles | 2022 |
New insight into the molecular mechanism of protein cross-linking induced by cis-2-butene-1,4-dial, the metabolite of furan: Formation of 2-substituted pyrrole cross-links involving the cysteine and lysine residues.
Topics: Acetylcysteine; Aldehydes; Animals; Biomarkers; Carcinogens; Chromatography, High Pressure Liquid; Furans; Lysine; Pyrroles; Rats; Tandem Mass Spectrometry | 2022 |