pyrroles has been researched along with 2-hydroxyatorvastatin in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 8 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kantola, T; Kivistö, KT; Neuvonen, PJ | 1 |
| Barrett, B; Borek-Dohalský, V; Huclová, J; Jelínek, I; Nemec, B; Ulc, I | 1 |
| Benet, LZ; Frassetto, L; Huang, Y; Lau, YY | 1 |
| Chaikin, P; Dvorchik, B; Mori, A; Rao, N; Sussman, N; Uchimura, T; Wang, H; Yamamoto, K | 1 |
| Jani, AJ; Mehta, AA; Rathnam, S | 1 |
| Brunet, M; Cofán, F; Cofán, M; Guillén, D; Millán, O; Rimola, A; Ros, E | 1 |
| Chung, JY; Jang, SB; Lee, MG; Lee, YJ; Lim, LA | 1 |
| Abel, R; Alvey, C; Bullen, W; Hartman, D; Porcari, AR; Whitfield, LR | 1 |
| Alarcón, E; Ebensperger, R; González-Béjar, M; Gorelsky, S; Lopez-Alarcón, C; Netto-Ferreira, JC; Scaiano, JC | 1 |
| Dong, FY; Gu, XL; He, BX; Hong, CJ; Li, R; Qiu, J; Shi, L; Tao, L; Yang, L; Zeng, XH; Zhao, SJ | 1 |
| Chakraborty, BS; Gaur, S; Ghosh, C; Jain, I; Patel, N; Upadhyay, A | 1 |
| Cho, JY; Jang, IJ; Kim, SE; Kim, TE; Lee, MG; Shin, KH; Shin, SG; Song, IS; Yoon, SH; Yu, KS | 1 |
| Buianova, SV; Korobov, GD; Osochuk, SS | 1 |
| Jacob, RF; Mason, RP; Self-Medlin, Y; Walter, MF | 1 |
7 trial(s) available for pyrroles and 2-hydroxyatorvastatin
| Article | Year |
|---|---|
Effect of itraconazole on the pharmacokinetics of atorvastatin.
Topics: Adult; Anticholesteremic Agents; Antifungal Agents; Area Under Curve; Atorvastatin; Cross-Over Studies; Double-Blind Method; Drug Interactions; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl CoA Reductases; Itraconazole; Male; Pyrroles; Smoking | 1998 |
effect of OATP1B transporter inhibition on the pharmacokinetics of atorvastatin in healthy volunteers.
Topics: Administration, Oral; Adolescent; Adult; Area Under Curve; Atorvastatin; Bile; Binding, Competitive; Biological Transport; Cell Line; Cross-Over Studies; Enzyme Inhibitors; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infusions, Intravenous; Liver; Liver-Specific Organic Anion Transporter 1; Male; Middle Aged; Organic Anion Transporters; Pyrroles; Rifampin; Substrate Specificity; Tablets; Transfection | 2007 |
A study of the pharmacokinetic interaction of istradefylline, a novel therapeutic for Parkinson's disease, and atorvastatin.
Topics: Administration, Oral; Antiparkinson Agents; Atorvastatin; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biotransformation; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Double-Blind Method; Drug Interactions; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Purines; Pyrroles | 2008 |
Phenotyping of cytochrome P450 3A enzyme in Gujarat population.
Topics: Adult; Atorvastatin; Cytochrome P-450 CYP3A; Female; Gene Frequency; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; India; Isoenzymes; Male; Phenotype; Polymorphism, Genetic; Pyrroles; Young Adult | 2008 |
Effects of SLCO1B1 and ABCB1 genotypes on the pharmacokinetics of atorvastatin and 2-hydroxyatorvastatin in healthy Korean subjects.
Topics: Adult; Alleles; Area Under Curve; Asian People; Atorvastatin; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 CYP3A; Female; Genotype; Half-Life; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Korea; Lactones; Liver-Specific Organic Anion Transporter 1; Male; Organic Anion Transporters; Pyrroles; Young Adult | 2010 |
Effect of gemfibrozil and fenofibrate on the pharmacokinetics of atorvastatin.
Topics: Adult; Atorvastatin; Biotransformation; Cross-Over Studies; Drug Interactions; Enzyme Inhibitors; Female; Fenofibrate; Gemfibrozil; Half-Life; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Lactones; Male; Middle Aged; Pyrroles | 2011 |
The effect of the newly developed angiotensin receptor II antagonist fimasartan on the pharmacokinetics of atorvastatin in relation to OATP1B1 in healthy male volunteers.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Area Under Curve; Atorvastatin; Biphenyl Compounds; Cross-Over Studies; Drug Interactions; Estrone; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver-Specific Organic Anion Transporter 1; Male; Organic Anion Transporters; Pyrimidines; Pyrroles; RNA, Complementary; Tetrazoles; Young Adult | 2011 |
7 other study(ies) available for pyrroles and 2-hydroxyatorvastatin
| Article | Year |
|---|---|
Validated HPLC-MS-MS method for simultaneous determination of atorvastatin and 2-hydroxyatorvastatin in human plasma-pharmacokinetic study.
Topics: Anticholesteremic Agents; Atorvastatin; Chromatography, High Pressure Liquid; Heptanoic Acids; Humans; Pyrroles; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2006 |
Determination of atorvastatin and its metabolite ortho-hydroxyatorvastatin in human plasma by on-line anion-exchange solid-phase extraction and liquid chromatography tandem mass spectrometry.
Topics: Adult; Aged; Anions; Atorvastatin; Chromatography, Liquid; Female; Heptanoic Acids; Humans; Male; Middle Aged; Online Systems; Pyrroles; Solid Phase Extraction; Tandem Mass Spectrometry | 2009 |
Photophysical characterization of atorvastatin (Lipitor®) ortho-hydroxy metabolite: role of hydroxyl group on the drug photochemistry.
Topics: Atorvastatin; Energy Transfer; Heptanoic Acids; Hydrogen; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Methanol; Photochemical Processes; Photolysis; Pyrroles; Quantum Theory; Singlet Oxygen; Thermodynamics | 2010 |
Quantitative determination of atorvastatin and ortho-hydroxy atorvastatin in human plasma by liquid chromatography tandem mass spectrometry and pharmacokinetic evaluation.
Topics: Area Under Curve; Atorvastatin; Chromatography, High Pressure Liquid; Heptanoic Acids; Humans; Pyrroles; Reproducibility of Results; Tandem Mass Spectrometry; Time Factors | 2010 |
Simultaneous estimation of atorvastatin and its two metabolites from human plasma by ESI-LC-MS/MS.
Topics: Atorvastatin; Calibration; Chromatography, High Pressure Liquid; Drug Stability; Heptanoic Acids; Humans; Molecular Structure; Pyrroles; Reproducibility of Results; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Therapeutic Equivalency | 2011 |
[The composition of blood lipoproteins of donors 2 hours later after single atorvastatin intake].
Topics: Anticholesteremic Agents; Atorvastatin; Biological Transport, Active; Female; Heptanoic Acids; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Male; Pyrroles; Sex Characteristics; Time Factors | 2011 |
Atorvastatin active metabolite inhibits oxidative modification of small dense low-density lipoprotein.
Topics: Antioxidants; Atorvastatin; Chemical Phenomena; Copper Sulfate; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Peroxides; Lipoproteins, LDL; Lipoproteins, VLDL; Liposomes; Osmolar Concentration; Oxidants; Oxidation-Reduction; Oxidative Stress; Particle Size; Prodrugs; Pyrroles; Ultracentrifugation; Unilamellar Liposomes | 2013 |