Page last updated: 2024-08-18

pyrroles and 1-methylimidazole

pyrroles has been researched along with 1-methylimidazole in 40 studies

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (10.00)	18.2507
2000's	24 (60.00)	29.6817
2010's	12 (30.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Baird, EE; Dervan, PB; Kelly, JJ	1
Baird, EE; Dervan, PB; Gottesfeld, JM; Neely, L; Trauger, JW	1
Baird, EE; Bremer, RE; Dervan, PB	1
Baird, EE; Breslauer, KJ; Dervan, PB; Pilch, DS; Poklar, N	1
Baraldi, PG; Bianchi, N; Cozzi, P; Gambari, R; Mongelli, N; Romagnoli, R; Spalluto, G	1
Baird, EE; Baliga, R; Crothers, DM; Dervan, PB; Herman, DM; Melander, C	1
Baird, EE; Dervan, PB; Nguyen, DH; Szewczyk, JW	1
Fen Zhao, Y; Jin Zhu, C; Liu, D; Liu, Y; Tang, F; Wang, J; Yuan, G	1
Dervan, PB; Weyermann, P	1
Arora, PS; Beerman, TA; Belitsky, JM; Dervan, PB; Leslie, SJ	1
Baird, EE; Dervan, PB; Hawkins, CA; Wemmer, DE	1
Huang, W; Tang, F; Xiao, J; Yuan, G; Zhou, Y	1
Dervan, PB; Jitianu, C; Olenyuk, B	1
Bando, T; Kawakami, W; Narita, A; Oyoshi, T; Sugiyama, H	1
Bando, T; Narita, A; Saito, I; Sugiyama, H	1
Liu, Y; Tang, F; Yuan, G; Zhao, YF; Zhu, CJ	1
Yuan, G; Zhou, J	3
Asada, K; Ayame, H; Bando, T; Narita, A; Sugiyama, H	1
Dervan, PB; Doss, RM; Foister, S; Marques, MA	1
Wang, J; Yuan, G; Zhou, J	1
Li, H; Tang, F; Yuan, G; Zhou, J	1
Cao, S; Niu, M; Ye, Y; Zhang, Z; Zhao, Y	1
Cai, S; Hui, L; Ji, Z; Li, J; Yuan, G; Zhou, J	1
Bando, T; Kashiwazaki, G; Minoshima, M; Nishijima, S; Shinohara, K; Sugiyama, H	2
Gao, PH; Jiang, YY; Li, P; Zhang, DZ; Zhu, SL	1
Burley, GA; Dondi, R; Gray, SJ; Su, W	1
Bando, T; Shinohara, K; Sugiyama, H	1
Aoyama, T; Bando, T; Fukuda, N; Katakawa, M; Matsuda, H; Matsui, S; Matsumoto, K; Matsumoto, Y; Nagase, H; Saito, K; Sugiyama, H; Ueno, T; Wang, X; Watanabe, T	1
He, X; Li, S; Lin, S; Xu, M; Yuan, G; Zhou, J	1
Bando, T; Hashiya, K; Kashiwazaki, G; Kitano, M; Sugiyama, H; Takagaki, T	1
Li, D; Wu, C; Yu, N; Zang, H	1
Asamitsu, S; Bando, T; Hashiya, K; Kawamoto, Y; Nagase, H; Sugiyama, H; Takenaka, T; Taylor, RD; Yamamoto, M	1
Bando, T; Hashiya, K; Kawamoto, Y; Sugiyama, H; Taylor, RD	1
Han, YW; Harada, Y; Sugiyama, H	1
Ansari, AZ; Bhimsaria, D; Eguchi, A; Erwin, GS; Grieshop, MP; Rodríguez-Martínez, JA	1
Bando, T; Chandran, A; Li, Y; Sato, S; Sugiyama, H; Syed, J	1
Ansari, AZ; Blainey, PC; Erwin, GS; Xiong, K	1

Reviews

2 review(s) available for pyrroles and 1-methylimidazole

Article	Year
[Advances in the chemical and biological studies of polyamides]. Yao xue xue bao = Acta pharmaceutica Sinica, 2008, Volume: 43, Issue:11 Topics: Animals; Base Pairing; DNA; DNA Footprinting; Gene Expression Regulation; Imidazoles; Nylons; Pyrroles	2008
Anticancer activities of alkylating pyrrole-imidazole polyamides with specific sequence recognition. Anti-cancer drugs, 2010, Volume: 21, Issue:3 Topics: Antineoplastic Agents, Alkylating; Base Sequence; Cell Line, Tumor; Gene Silencing; Humans; Imidazoles; Nylons; Pyrroles; Xenograft Model Antitumor Assays	2010

Other Studies

38 other study(ies) available for pyrroles and 1-methylimidazole

Article	Year
Binding site size limit of the 2:1 pyrrole-imidazole polyamide-DNA motif. Proceedings of the National Academy of Sciences of the United States of America, 1996, Jul-09, Volume: 93, Issue:14 Topics: Amides; Amino Acids; Base Sequence; Binding Sites; DNA; Imidazoles; Kinetics; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Oligodeoxyribonucleotides; Pyrroles; Structure-Activity Relationship	1996
Regulation of gene expression by small molecules. Nature, 1997, May-08, Volume: 387, Issue:6629 Topics: Animals; Binding Sites; Cell Line; DNA; DNA Footprinting; DNA-Binding Proteins; Gene Expression Regulation; Imidazoles; Molecular Structure; Nylons; Pyrroles; RNA, Ribosomal, 5S; RNA, Transfer; Transcription Factor TFIIIA; Transcription Factors; Transcription, Genetic; Xenopus; Zinc Fingers	1997
Inhibition of major-groove-binding proteins by pyrrole-imidazole polyamides with an Arg-Pro-Arg positive patch. Chemistry & biology, 1998, Volume: 5, Issue:3 Topics: DNA-Binding Proteins; Fungal Proteins; Imidazoles; Ligands; Nylons; Oligopeptides; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Pyrroles; Saccharomyces cerevisiae Proteins; Salts	1998
The thermodynamics of polyamide-DNA recognition: hairpin polyamide binding in the minor groove of duplex DNA. Biochemistry, 1999, Feb-16, Volume: 38, Issue:7 Topics: Base Pair Mismatch; beta-Alanine; Binding Sites; Circular Dichroism; DNA; gamma-Aminobutyric Acid; Imidazoles; Ligands; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Nylons; Pyrroles; Spectrophotometry, Ultraviolet; Thermodynamics	1999
DNA sequence-recognizing properties of minor groove alkylating agents. Effects of the replacement of N-methylpyrrole by an N-methylimidazole on tallimustine and its own homologue. Arzneimittel-Forschung, 2000, Volume: 50, Issue:3 Topics: Animals; Antineoplastic Agents, Alkylating; Distamycins; DNA; DNA Primers; Female; Genes, ras; Humans; Imidazoles; Leukemia L1210; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Nitrogen Mustard Compounds; Polymerase Chain Reaction; Pyrroles; Receptors, Estrogen; Structure-Activity Relationship	2000
Kinetic consequences of covalent linkage of DNA binding polyamides. Biochemistry, 2001, Jan-09, Volume: 40, Issue:1 Topics: 2-Aminopurine; Binding Sites; DNA; DNA-Binding Proteins; Imidazoles; Kinetics; Ligands; Nucleic Acid Conformation; Nylons; Pyrroles; Spectrometry, Fluorescence	2001
Alternative heterocycles for DNA recognition: an N-methylpyrazole/N-methylpyrrole pair specifies for A.T/T.A base pairs. Bioorganic & medicinal chemistry, 2001, Volume: 9, Issue:1 Topics: Base Pairing; Base Sequence; Binding Sites; DNA; Imidazoles; Molecular Sequence Data; Nylons; Pyrazoles; Pyrroles	2001
Electrospray ionization tandem mass spectrometric characteristics and fragmentation mechanisms of distamycin analogues. Rapid communications in mass spectrometry : RCM, 2002, Volume: 16, Issue:11 Topics: Antiviral Agents; Distamycins; Imidazoles; Molecular Structure; Pyrroles; Spectrometry, Mass, Electrospray Ionization	2002
Recognition of ten base pairs of DNA by head-to-head hairpin dimers. Journal of the American Chemical Society, 2002, Jun-19, Volume: 124, Issue:24 Topics: Base Sequence; Binding Sites; DNA; Hydrogen Bonding; Imidazoles; Kinetics; Molecular Sequence Data; Nucleic Acid Conformation; Nylons; Pyrroles	2002
Cellular uptake of N-methylpyrrole/N-methylimidazole polyamide-dye conjugates. Bioorganic & medicinal chemistry, 2002, Volume: 10, Issue:10 Topics: Boron Compounds; Cell Compartmentation; Cell Nucleus; Cytoplasm; Fluorescent Dyes; Humans; Imidazoles; Microscopy, Confocal; Nylons; Pyrroles; T-Lymphocytes; Tumor Cells, Cultured	2002
Analysis of hairpin polyamide complexes having DNA binding sites in close proximity. Journal of the American Chemical Society, 2002, Oct-30, Volume: 124, Issue:43 Topics: Binding Sites; DNA; Imidazoles; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Nylons; Pyrroles	2002
Synthesis of polyamides containing N-methylpyrrole and N-methylimidazole and their anticancer activity. Archives of pharmacal research, 2002, Volume: 25, Issue:5 Topics: Antineoplastic Agents; Drug Screening Assays, Antitumor; Imidazoles; Nylons; Pyrroles; Tumor Cells, Cultured	2002
Parallel synthesis of H-pin polyamides by alkene metathesis on solid phase. Journal of the American Chemical Society, 2003, Apr-23, Volume: 125, Issue:16 Topics: Alkenes; Base Sequence; DNA; Imidazoles; Kinetics; Molecular Sequence Data; Nucleic Acid Conformation; Nylons; Pyrroles; Substrate Specificity	2003
Inhibition of transcription at a coding sequence by alkylating polyamide. Journal of the American Chemical Society, 2003, Apr-23, Volume: 125, Issue:16 Topics: Alkylation; DNA; Electrophoresis, Polyacrylamide Gel; Imidazoles; Nylons; Pyrroles; RNA, Messenger; Transcription Factors; Transcription, Genetic	2003
Molecular design of hairpin imidazole-pyrrole polyamide for effective DNA alkylation. Nucleic acids research. Supplement (2001), 2001, Issue:1 Topics: Alkylation; DNA; Imidazoles; Nucleic Acid Conformation; Nylons; Purines; Pyrroles	2001
Fragmentation mechanisms of polyamides containing N-methylpyrrole and N-methylimidazole by electrospray ionization tandem mass spectrometry. Rapid communications in mass spectrometry : RCM, 2003, Volume: 17, Issue:17 Topics: Imidazoles; Indicators and Reagents; Nylons; Pyrroles; Spectrometry, Mass, Electrospray Ionization	2003
Electrospray ionization mass spectral fragmentation mechanisms of DNA-recognizing polyamides containing N-methylpyrrole and N-methylimidazol. Rapid communications in mass spectrometry : RCM, 2004, Volume: 18, Issue:12 Topics: DNA; Imidazoles; Pyrroles; Spectrometry, Mass, Electrospray Ionization	2004
Electrospray ionization mass spectrometric analysis of noncovalent complexes between DNA and polyamides containing N-methylpyrrole and N-methylimidazole. Rapid communications in mass spectrometry : RCM, 2004, Volume: 18, Issue:13 Topics: DNA; DNA, Single-Stranded; Imidazoles; Molecular Structure; Nylons; Pyrroles; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship	2004
Enantioselective DNA alkylation by a pyrrole-imidazole S-CBI conjugate. Journal of the American Chemical Society, 2004, Jul-28, Volume: 126, Issue:29 Topics: Alkylation; Chromatography, High Pressure Liquid; Cyclopropanes; DNA; Imidazoles; Indoles; Models, Molecular; Nucleic Acid Conformation; Oligonucleotides; Pyrroles; Stereoisomerism; Thermodynamics	2004
Expanding the repertoire of heterocycle ring pairs for programmable minor groove DNA recognition. Journal of the American Chemical Society, 2004, Aug-25, Volume: 126, Issue:33 Topics: Base Pairing; Benzimidazoles; Deoxyribonuclease I; DNA; DNA Footprinting; Imidazoles; Indazoles; Kinetics; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Nylons; Pyrroles	2004
Analysis of noncovalent complexes between human telomeric DNA and polyamides containing N-methylpyrrole and N-methylimidazole by using electrospray ionization mass spectrometry. Chemistry (Weinheim an der Bergstrasse, Germany), 2005, Feb-04, Volume: 11, Issue:4 Topics: DNA; Humans; Imidazoles; Molecular Structure; Nylons; Oligonucleotides; Pyrroles; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Telomere	2005
Electrospray negative ionization mass spectrometry of polyamides containing N-methylpyrrole and N-methylimidazole. Journal of mass spectrometry : JMS, 2005, Volume: 40, Issue:5 Topics: Imidazoles; Molecular Structure; Nylons; Pyrroles; Spectrometry, Mass, Electrospray Ionization	2005
Investigation of noncovalent complexes between beta-cyclodextrin and polyamide acids containing N-methylpyrrole and N-methylimidazole by electrospray ionization mass spectrometry. Journal of the American Society for Mass Spectrometry, 2006, Volume: 17, Issue:1 Topics: Algorithms; beta-Cyclodextrins; Imidazoles; Linear Models; Nylons; Pyrroles; Spectrometry, Mass, Electrospray Ionization	2006
Amino-catalyzed fragmentation characteristics of polyamides containing N-methylpyrrole and N-methylimidazole by electrospray negative ionization mass spectrometry. Rapid communications in mass spectrometry : RCM, 2006, Volume: 20, Issue:7 Topics: Catalysis; Imidazoles; Nylons; Pyrroles; Spectrometry, Mass, Electrospray Ionization	2006
Studies on electrochemical oxidation mechanisms of polyamides containing N-methylpyrrole and N-methylimidazole by electrospray ionization tandem mass spectrometry. The journal of physical chemistry. B, 2005, Sep-15, Volume: 109, Issue:36 Topics: Electrochemistry; Imidazoles; Nylons; Oxidation-Reduction; Pyrroles; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry	2005
Cooperative alkylation of double-strand human telomere repeat sequences by PI polyamides with 11-base-pair recognition based on a heterotrimeric design. Bioorganic & medicinal chemistry, 2009, Feb-01, Volume: 17, Issue:3 Topics: Alkylating Agents; Alkylation; Base Pairing; Base Sequence; Cell Line; Distamycins; DNA; Humans; Imidazoles; Jurkat Cells; Nylons; Pyrroles; Repetitive Sequences, Nucleic Acid; Telomere	2009
Highly efficient synthesis of DNA-binding hairpin polyamides via the use of a new triphosgene coupling strategy. Organic letters, 2009, Sep-03, Volume: 11, Issue:17 Topics: DNA; Imidazoles; Molecular Structure; Nylons; Pyrroles	2009
Cell permeability of Py-Im-polyamide-fluorescein conjugates: Influence of molecular size and Py/Im content. Bioorganic & medicinal chemistry, 2010, Jan-15, Volume: 18, Issue:2 Topics: Cell Line; Cell Membrane Permeability; Chromosome Mapping; Fluorescein; Humans; Imidazoles; K562 Cells; Molecular Structure; Molecular Weight; Nylons; Pyrroles; Stereoisomerism; Tissue Distribution	2010
Transcriptional inhibition of progressive renal disease by gene silencing pyrrole-imidazole polyamide targeting of the transforming growth factor-β1 promoter. Kidney international, 2011, Volume: 79, Issue:1 Topics: Amino Acids; Animals; Fibrosis; Gene Expression Regulation; Gene Silencing; Genetic Therapy; Glomerulosclerosis, Focal Segmental; Imidazoles; Kidney Glomerulus; Male; Nylons; Promoter Regions, Genetic; Pyrroles; Rats; Rats, Inbred Dahl; RNA, Messenger; Transcription, Genetic; Transforming Growth Factor beta1	2011
Investigation of non-covalent interaction of ANF promoter DNA and polyamides containing N-methylimidazole and N-methylpyrrole amino acids by electrospray ionization mass spectrometry. Rapid communications in mass spectrometry : RCM, 2011, Apr-15, Volume: 25, Issue:7 Topics: Atrial Natriuretic Factor; Binding Sites; Circular Dichroism; DNA; Gene Expression Regulation; Humans; Imidazoles; Nylons; Promoter Regions, Genetic; Pyrroles; Spectrometry, Mass, Electrospray Ionization	2011
Evaluation of PI polyamide conjugates with eight-base pair recognition and improvement of the aqueous solubility by PEGylation. Bioorganic & medicinal chemistry, 2011, Oct-01, Volume: 19, Issue:19 Topics: Antineoplastic Agents, Alkylating; Base Pairing; Cell Line, Tumor; Drug Design; Electrophoresis, Polyacrylamide Gel; Humans; Imidazoles; Nylons; Polyethylene Glycols; Pyrroles; Solubility; Water	2011
1-Methylimidazolium hydrogen sulfate catalyzed convenient synthesis of 2,5-dimethyl-N-substituted pyrroles under ultrasonic irradiation. Ultrasonics sonochemistry, 2013, Volume: 20, Issue:5 Topics: Catalysis; Imidazoles; Molecular Structure; Pyrroles; Sonication	2013
Sequence-specific DNA alkylation targeting for Kras codon 13 mutation by pyrrole-imidazole polyamide seco-CBI conjugates. Chemistry (Weinheim an der Bergstrasse, Germany), 2014, Jan-27, Volume: 20, Issue:5 Topics: Alanine; Alkylation; Base Pairing; Base Sequence; Codon; DNA; Humans; Imidazoles; Models, Molecular; Mutation; Nylons; Pyrroles; ras Proteins	2014
Sequence-specific DNA alkylation by tandem Py-Im polyamide conjugates. Chemistry, an Asian journal, 2014, Volume: 9, Issue:9 Topics: Alkylation; Base Sequence; DNA; Imidazoles; Models, Molecular; Molecular Structure; Nylons; Pyrroles	2014
The application of fluorescence-conjugated pyrrole/imidazole polyamides in the characterization of protein-DNA complex formation. Biomaterials science, 2016, Volume: 4, Issue:3 Topics: Base Sequence; DNA; Fluorescence; Imidazoles; Nucleosomes; Nylons; Pyrroles; Transcription Factors	2016
Genome-wide Mapping of Drug-DNA Interactions in Cells with COSMIC (Crosslinking of Small Molecules to Isolate Chromatin). Journal of visualized experiments : JoVE, 2016, Jan-20, Issue:107 Topics: Binding Sites; Chromatin; DNA; Genome-Wide Association Study; Humans; Imidazoles; Nylons; Pyrroles; Small Molecule Libraries	2016
Genome-Wide Assessment of the Binding Effects of Artificial Transcriptional Activators by High-Throughput Sequencing. Chembiochem : a European journal of chemical biology, 2016, 10-17, Volume: 17, Issue:20 Topics: Binding Sites; DNA; High-Throughput Nucleotide Sequencing; Humans; Hydroxamic Acids; Imidazoles; Molecular Structure; Nylons; Pyrroles; Vorinostat	2016
Sliding on DNA: From Peptides to Small Molecules. Angewandte Chemie (International ed. in English), 2016, 11-21, Volume: 55, Issue:48 Topics: DNA; Imidazoles; Molecular Conformation; Nylons; Peptides; Pyrroles	2016