Page last updated: 2024-09-04

pyrrole-2,3,5-tricarboxylic acid and pyrroles

pyrrole-2,3,5-tricarboxylic acid has been researched along with pyrroles in 31 studies

Compound Research Comparison

Studies
(pyrrole-2,3,5-tricarboxylic acid)
Trials
(pyrrole-2,3,5-tricarboxylic acid)
Recent Studies (post-2010)
(pyrrole-2,3,5-tricarboxylic acid)
Studies
(pyrroles)
Trials
(pyrroles)
Recent Studies (post-2010) (pyrroles)
340926,1292,81512,100

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (25.81)18.2507
2000's13 (41.94)29.6817
2010's7 (22.58)24.3611
2020's3 (9.68)2.80

Authors

AuthorsStudies
Brinck, C; Carstam, R; Hindemith-Augustsson, A; Rorsman, H; Rosengren, E1
Carstam, R; Hindemith, A; Odh, G; Paulson, J; Rorsman, H; Rosengren, E1
Ito, S; Wakamatsu, K2
Cuevas, AA; García-Castiñeiras, S1
Ito, S; Ozeki, H; Thody, AJ; Wakamatsu, K1
Ishiguro, I; Ito, S; Ozeki, H; Wakamatsu, K1
Ito, S; Nakamura, A; Niwa, T; Shiojiri, N; Wakamatsu, K1
Ahlner, J; Förstberg-Peterson, S; Kågedal, B; Kronstrand, R; Larson, G1
Di Donato, P; Monfrecola, G; Napolitano, A; Prota, G; Vincensi, MR1
Bhardwaj, R; Blanchard, J; Brooks, C; Dorr, RT; Dvorakova, K; Hadley, ME1
Abe, H; Hirobe, T; Ito, S; Kawa, Y; Mizoguchi, M; Wakamatsu, K1
Anderson, PJ; Morris, JG; Rogers, QR1
Arstrand, K; Johansson, M; Kågedal, B; Lenner, L; Takasaki, A1
Fujikawa, K; Ito, S; Wakamatsu, K; Zecca, L; Zucca, FA1
Hirobe, T; Ito, S; Wakamatsu, K2
Innocenti, R; Loria, DI; Mossotti, R; Rosso, S; Zanetti, R; Zoccola, M2
Brown, R; Fountain, S; Kindt, E; Szekely-Klepser, G; Wade, K; Woolson, D1
Hirobe, T; Ito, S; Kawa, Y; Mizoguchi, M; Soma, Y; Wakamatsu, K1
Balzi, D; Barbera, C; Chirlaque, MD; Fabbrocini, G; Greinert, R; Lauria, C; Loria, D; Mercier, M; Miranda, A; Nieto, A; Rosso, S; Sánchez, MJ; Sancho-Garnier, H; Zanetti, R; Zoccola, M; Østerlind, A1
d'Ischia, M; Manini, P; Monfrecola, G; Napolitano, A; Panzella, L1
Adachi, K; Ito, S; Kato, K; Matsubara, H; Nomura, K; Tanaka, H; Wakamatsu, K1
Brilliant, MH; Ito, S; Kolbe, L; Nakanishi, Y; Valenzuela, RK; Wakamatsu, K1
Bernard, BA; Commo, S; Ito, S; Loussouarn, G; Lozano, I; Panhard, S; Wakamatsu, K1
Ito, S; Sarna, T; Wakamatsu, K1
Meier, SI; Petzel-Witt, S; Schubert-Zsilavecz, M; Toennes, SW1
Del Bino, S; Hirobe, T; Ito, S; Wakamatsu, K1
Angeli, I; Bergamaschi, RF; Brini, AT; Casati, S; Giannasi, C; Guzzi, A; Minoli, M; Orioli, M; Ravelli, A1
Angeli, I; Bergamaschi, RF; Binelli, G; Casati, S; Minoli, M; Orioli, M; Ravelli, A1

Reviews

2 review(s) available for pyrrole-2,3,5-tricarboxylic acid and pyrroles

ArticleYear
Diversity of human hair pigmentation as studied by chemical analysis of eumelanin and pheomelanin.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2011, Volume: 25, Issue:12

    Topics: Hair Color; Humans; Hydrogen Peroxide; Melanins; Oxidation-Reduction; Pyrroles

2011
Photodegradation of Eumelanin and Pheomelanin and Its Pathophysiological Implications.
    Photochemistry and photobiology, 2018, Volume: 94, Issue:3

    Topics: Carboxylic Acids; Eye; Humans; Hydrogen Peroxide; Light; Melanins; Melanosomes; Pyrroles; Reactive Oxygen Species; Retinal Pigment Epithelium; Skin; Skin Aging; Thiazoles; Tyrosine; Ultraviolet Rays

2018

Other Studies

29 other study(ies) available for pyrrole-2,3,5-tricarboxylic acid and pyrroles

ArticleYear
The neuromelanin of the human substantia nigra.
    Biochimica et biophysica acta, 1991, Sep-23, Volume: 1097, Issue:2

    Topics: Chromatography, High Pressure Liquid; Cysteine; Dopamine; Glutathione; Humans; Melanins; Pyrroles; Substantia Nigra; Tyramine; Tyrosine

1991
Melanins in IGR 1 melanoma cells.
    Pigment cell research, 1994, Volume: 7, Issue:6

    Topics: Chromatography, Liquid; Cysteinyldopa; Dicarboxylic Acids; Humans; Hydrolysis; Mass Spectrometry; Melanins; Melanoma; Monophenol Monooxygenase; Neoplasm Proteins; Oxidation-Reduction; Potassium Permanganate; Pyrroles; Sulfur; Thiazoles; Tumor Cells, Cultured; Tyrosine

1994
An improved modification of permanganate oxidation of eumelanin that gives a constant yield of pyrrole-2,3,5-tricarboxylic acid.
    Pigment cell research, 1994, Volume: 7, Issue:3

    Topics: Animals; Chromatography, High Pressure Liquid; Hair; Humans; Liver; Melanins; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Potassium Permanganate; Pyrroles; Tumor Cells, Cultured

1994
Melanins and lens pigments: a comparative study.
    Puerto Rico health sciences journal, 1993, Volume: 12, Issue:2

    Topics: Cataract; Chromatography, High Pressure Liquid; Dicarboxylic Acids; Lens, Crystalline; Melanins; Pigments, Biological; Pyrroles; Thiazoles

1993
Spectrophotometric characterization of eumelanin and pheomelanin in hair.
    Pigment cell research, 1996, Volume: 9, Issue:5

    Topics: Animals; Chromatography, High Pressure Liquid; Hair; Humans; Melanins; Mice; Pyrroles; Sheep; Spectrophotometry; Tyrosine

1996
Chemical characterization of eumelanins with special emphasis on 5,6-dihydroxyindole-2-carboxylic acid content and molecular size.
    Analytical biochemistry, 1997, May-15, Volume: 248, Issue:1

    Topics: Animals; Dihydroxyphenylalanine; Humans; Indoles; Melanins; Mice; Molecular Weight; Polymers; Pyrroles; Quaternary Ammonium Compounds; Solvents; Spectrophotometry; Tyrosine

1997
Chemical analysis of melanin pigments in feather germs of Japanese quail Bh (black at hatch) mutants.
    Pigment cell research, 1999, Volume: 12, Issue:4

    Topics: Animals; Chromatography, High Pressure Liquid; Coturnix; Embryo, Nonmammalian; Feathers; Female; Heterozygote; Homozygote; Male; Melanins; Mice; Mice, Inbred C57BL; Mutation; Pigmentation; Pyrroles; Tyrosine

1999
Codeine concentration in hair after oral administration is dependent on melanin content.
    Clinical chemistry, 1999, Volume: 45, Issue:9

    Topics: Chromatography, High Pressure Liquid; Codeine; Female; Gas Chromatography-Mass Spectrometry; Hair; Humans; Male; Melanins; Morphine; Narcotics; Pyrroles; Substance Abuse Detection

1999
Microanalysis of melanins in mammalian hair by alkaline hydrogen peroxide degradation: identification of a new structural marker of pheomelanins.
    The Journal of investigative dermatology, 2000, Volume: 114, Issue:6

    Topics: Animals; Biomarkers; Chromatography, High Pressure Liquid; Hair; Humans; Hydrogen Peroxide; Melanins; Mice; Microchemistry; Pyrroles

2000
Pharmacologic response of a controlled-release PLGA formulation for the alpha-melanocyte stimulating hormone analog, Melanotan-I.
    Pharmaceutical research, 2000, Volume: 17, Issue:5

    Topics: alpha-MSH; Animals; Anticarcinogenic Agents; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Drug Carriers; Drug Implants; Guinea Pigs; Lactic Acid; Melanins; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pyrroles; Rana pipiens; Skin

2000
Stimulation of the proliferation and differentiation of mouse pink-eyed dilution epidermal melanocytes by excess tyrosine in serum-free primary culture.
    Journal of cellular physiology, 2002, Volume: 191, Issue:2

    Topics: Animals; Carrier Proteins; Cell Differentiation; Cell Division; Cells, Cultured; Culture Media, Serum-Free; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Epidermis; Female; Indoles; Male; Melanins; Melanocytes; Membrane Glycoproteins; Membrane Proteins; Mice; Mice, Inbred Strains; Monophenol Monooxygenase; Oxidoreductases; Proteins; Proto-Oncogene Proteins c-kit; Pyrroles; Tyrosine

2002
Cats require more dietary phenylalanine or tyrosine for melanin deposition in hair than for maximal growth.
    The Journal of nutrition, 2002, Volume: 132, Issue:7

    Topics: Animals; Cats; Diet; Dose-Response Relationship, Drug; Hair; Hair Color; Melanins; Nutritional Requirements; Osmolar Concentration; Phenylalanine; Pyrroles; Tyrosine

2002
Quantitative relationships between pigment-related mRNA and biochemical melanoma markers in melanoma cell lines.
    Melanoma research, 2002, Volume: 12, Issue:3

    Topics: Antigens, Neoplasm; Biomarkers, Tumor; Gene Expression Profiling; Humans; Intramolecular Oxidoreductases; MART-1 Antigen; Melanins; Melanoma; Membrane Glycoproteins; Monophenol Monooxygenase; Neoplasm Proteins; Neoplastic Cells, Circulating; Nerve Growth Factors; Oxidoreductases; Pigmentation; Polymerase Chain Reaction; Proteins; Pyrroles; RNA, Messenger; RNA, Neoplasm; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Tumor Cells, Cultured; Tyrosine

2002
The structure of neuromelanin as studied by chemical degradative methods.
    Journal of neurochemistry, 2003, Volume: 86, Issue:4

    Topics: Aged; Aged, 80 and over; Dicarboxylic Acids; Female; Humans; Hydrogen Peroxide; Hydrolysis; Melanins; Molecular Structure; Oxidants; Oxidation-Reduction; Pyrroles; Substantia Nigra; Thiazoles; Tyramine

2003
Changes in the proliferation and differentiation of neonatal mouse pink-eyed dilution melanocytes in the presence of excess tyrosine.
    Pigment cell research, 2003, Volume: 16, Issue:6

    Topics: Animals; Animals, Newborn; Cell Differentiation; Cell Division; Cells, Cultured; Culture Media, Serum-Free; Cysteinyldopa; Indoles; Melanins; Melanocytes; Mice; Mice, Congenic; Mice, Transgenic; Mutation; Pyrroles; Tyrosine

2003
Near infrared spectroscopy as a tool for the determination of eumelanin in human hair.
    Pigment cell research, 2004, Volume: 17, Issue:4

    Topics: Chromatography, High Pressure Liquid; Hair; Humans; Melanins; Pyrroles; Spectroscopy, Near-Infrared

2004
A validated LC/MS/MS method for the quantification of pyrrole-2,3,5-tricarboxylic acid (PTCA), a eumelanin specific biomarker, in human skin punch biopsies.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Nov-05, Volume: 826, Issue:1-2

    Topics: Animals; Biomarkers; Biopsy; Black or African American; Chromatography, High Pressure Liquid; Humans; Mass Spectrometry; Melanins; Mice; Pyrroles; Reproducibility of Results; Sensitivity and Specificity; Skin; Skin Pigmentation; White People

2005
The slaty mutation affects eumelanin and pheomelanin synthesis in mouse melanocytes.
    European journal of cell biology, 2006, Volume: 85, Issue:6

    Topics: Animals; Cell Differentiation; Cells, Cultured; Culture Media; Dermis; Dihydroxyphenylalanine; Epidermal Cells; Female; Gene Expression Regulation, Developmental; Intramolecular Oxidoreductases; Kinetics; Male; Melanins; Melanocytes; Mice; Mice, Inbred C57BL; Mutation; Pyrroles; Skin; Tyrosine

2006
PTCA determination in human hair: reliability and analytical aspects.
    Medical science monitor : international medical journal of experimental and clinical research, 2006, Volume: 12, Issue:6

    Topics: Chromatography, High Pressure Liquid; Female; Hair; Humans; Male; Melanoma; Pyrroles; Reproducibility of Results; Risk

2006
Is 2,3,5-pyrroletricarboxylic acid in hair a better risk indicator for melanoma than traditional epidemiologic measures for skin phenotype?
    American journal of epidemiology, 2007, May-15, Volume: 165, Issue:10

    Topics: Adult; Aged; Bayes Theorem; Case-Control Studies; Hair; Humans; Male; Melanins; Melanoma; Middle Aged; Phenotype; Pyrroles; Risk Factors; Skin Neoplasms; Spectroscopy, Near-Infrared

2007
An easy-to-run method for routine analysis of eumelanin and pheomelanin in pigmented tissues.
    Pigment cell research, 2007, Volume: 20, Issue:2

    Topics: Biomarkers; Chromatography, High Pressure Liquid; Hair; Humans; Melanins; Molecular Structure; Pigmentation; Pyrroles; Skin Pigmentation

2007
A close relationship between androgen levels and eumelanogenesis in the teleost red seabream (Pagrus major): Quantitative analysis of its seasonal variation and effects of oral treatment with methyl-testosterone.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2010, Volume: 156, Issue:2

    Topics: Administration, Oral; Androgens; Animals; Biomarkers; Female; Gonads; Male; Melanins; Methyltestosterone; Pigmentation; Pyrroles; Sea Bream; Seasons; Testosterone

2010
Usefulness of alkaline hydrogen peroxide oxidation to analyze eumelanin and pheomelanin in various tissue samples: application to chemical analysis of human hair melanins.
    Pigment cell & melanoma research, 2011, Volume: 24, Issue:4

    Topics: Adolescent; Adult; Alkalies; Animals; Biomarkers; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Female; Hair; Humans; Hydrogen Peroxide; Male; Melanins; Mice; Organ Specificity; Oxidation-Reduction; Pyrroles; Time Factors; Young Adult

2011
Age-dependent changes in eumelanin composition in hairs of various ethnic origins.
    International journal of cosmetic science, 2012, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Asian People; Black or African American; Child; Female; Hair; Hair Color; Humans; Male; Melanins; Middle Aged; Pyrroles; Statistics, Nonparametric; White People; Young Adult

2012
The slaty (slt/Dct(slt) ) allele decreases the content of eumelanin, but not pheomelanin in the mouse hair.
    Pigment cell & melanoma research, 2016, Volume: 29, Issue:1

    Topics: Alleles; Animals; Dicarboxylic Acids; Genes, Recessive; Hair; Intramolecular Oxidoreductases; Melanins; Mice; Phenotype; Pigmentation; Pyrroles; Pyrrolidines

2016
PTCA (1H-pyrrole-2,3,5-tricarboxylic acid) as a marker for oxidative hair treatment.
    Drug testing and analysis, 2018, Volume: 10, Issue:4

    Topics: Biomarkers; Chromatography, High Pressure Liquid; Forensic Toxicology; Hair; Hair Preparations; Humans; Hydrogen Peroxide; Melanins; Oxidation-Reduction; Oxidative Stress; Pyrroles; Substance Abuse Detection; Tandem Mass Spectrometry

2018
Improved HPLC Conditions to Determine Eumelanin and Pheomelanin Contents in Biological Samples Using an Ion Pair Reagent.
    International journal of molecular sciences, 2020, Jul-20, Volume: 21, Issue:14

    Topics: Animals; Chromatography, High Pressure Liquid; Dicarboxylic Acids; Epidermis; Hair; Humans; Indicators and Reagents; Ions; Melanins; Mice; Pyrroles; Thiazoles

2020
Endogenous 1-H-Pyrrole-2,3,5-Tricarboxylic Acid (PTCA) in Hair and Its Forensic Applications: A Pilot Study on a Wide Multi-Ethnic Population.
    Journal of analytical toxicology, 2021, Mar-12, Volume: 45, Issue:3

    Topics: Hair; Pilot Projects; Pyrroles; Tricarboxylic Acids

2021
PTCA (1-H-Pyrrole-2,3,5-Tricarboxylic Acid) as a Marker for Oxidative Hair Treatment: Distribution, Gender Aspects, Correlation with EtG and Self-Reports.
    Journal of analytical toxicology, 2021, May-14, Volume: 45, Issue:5

    Topics: Alcohol Drinking; Alcoholism; Biomarkers; Glucuronates; Humans; Oxidative Stress; Pyrroles; Reproducibility of Results; Self Report; Substance Abuse Detection; Tricarboxylic Acids

2021