pyrophosphate and 5--thioadenosine

pyrophosphate has been researched along with 5--thioadenosine* in 1 studies

Other Studies

1 other study(ies) available for pyrophosphate and 5--thioadenosine

ArticleYear
Vibration Ball Milling for the Synthesis of 5'-Thioadenosine 5'-Pyrophosphate (P'→5') Adenosine (dASppA).
    Current protocols in nucleic acid chemistry, 2017, 09-18, Volume: 70

    Using vibration ball milling, 5'-chloro-5'-deoxyadenosine (CldA) reacts cleanly with 4-methoxybenzyl mercaptan (MobSH), under basic conditions, to the corresponding thioether (MobSdA), which is isolated following precipitation and trituration. Under acidic conditions, in a one-pot, two-step process, MobSdA is transformed into 5'-deoxy-5'-(5-nitropyridyl-2-disulfanyl)-adenosine (NPySSdA). Michaelis-Arbuzov (M-A) reaction of NPySSdA with tris(trimethylsilyl) phosphite proceeds to completion within 30 min as determined by

    Topics: Adenosine; Diphosphates; Thionucleosides; Vibration

2017