Page last updated: 2024-09-02

pyronaridine and pyrimethamine

pyronaridine has been researched along with pyrimethamine in 24 studies

Research

Studies (24)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (20.83)	18.7374
1990's	5 (20.83)	18.2507
2000's	2 (8.33)	29.6817
2010's	10 (41.67)	24.3611
2020's	2 (8.33)	2.80

Authors

Authors	Studies
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fidock, DA; Flannery, EL; Winzeler, EA	1
Avery, VM; Sykes, ML	1
Avery, V; Derese, S; Deyou, T; Duffy, S; Erdélyi, M; Fitzpatrick, PA; Gruhonjic, A; Gumula, I; Heydenreich, M; Holleran, J; Landberg, G; Mumo, M; Pang, F; Rissanen, K; Yenesew, A	1
Avery, VM; Carroll, AR; Duffy, S; Senadeera, SPD	1
Avery, VM; Carroll, AR; Duffy, S; Robertson, LP; Wang, D; Wang, Y	1
Avery, VM; Carroll, AR; Duffy, S; Lucantoni, L; Senadeera, SPD	1
Avery, VM; Butler, GS; Drinkwater, N; Duffy, S; Grin, PM; Kassiou, M; Lucantoni, L; Malcolm, TR; McGowan, S; Overall, CM; Scammells, PJ; Vinh, NB	1
Avery, VM; Carroll, AR; Duffy, S; Lucantoni, L; Robertson, LP	1
Avery, VM; Duffy, S; Erdélyi, M; Lindblad, S; Maeda, G; Munissi, JJE; Nyandoro, SS; Pelletier, J	1
Avery, VM; Challis, MP; Creek, DJ; De Paoli, A; Devine, SM; Kigotho, JK; MacRaild, CA; Norton, RS; Scammells, PJ; Siddiqui, G	1
Chen, C; Zheng, X	1
Huang, ZS; Meng, F; Shao, BR; Shi, XH	1
Shao, BR; Shi, XH; Ye, XY	1
Ha, SH; Huang, J; Huang, ZS; Meng, F; Shao, BR; Shi, XH; Ye, XY; Zhan, CQ	1
Shao, BR; Ye, XY	1
Guo, RN; Huang, J; Huang, ZS; Li, X; Meng, F; Shao, BR; Shi, XH; Xing, QF; Ye, XY; Zeng, LH	1
Cai, XZ; Chen, QY; Fu, SG; Lin, KH; Liu, HH; Liu, QJ; Liu, XM; Liu, YP; Ou, FZ; Pang, XJ	1
Boudreau, EF; Chen, C; Childs, GE; Häusler, B; Milhous, W; Pooyindee, N; Wimonwattrawatee, T	1
Yang, H; Yang, P; Yang, Y	1
Basco, LK; Le Bras, J	1
Auparakkitanon, S; Chavalitshewinkoon-Petmitr, P; Pongvilairat, G; Wilairat, P	1
Feng, XP; Han, XL; Liu, DQ	1
Clark, RL	1

Reviews

4 review(s) available for pyronaridine and pyrimethamine

Article	Year
Using genetic methods to define the targets of compounds with antimalarial activity. Journal of medicinal chemistry, 2013, Oct-24, Volume: 56, Issue:20 Topics: Animals; Anopheles; Antimalarials; Drug Resistance; Genetic Association Studies; Genome, Protozoan; Humans; Malaria, Falciparum; Molecular Targeted Therapy; Plasmodium falciparum	2013
Approaches to protozoan drug discovery: phenotypic screening. Journal of medicinal chemistry, 2013, Oct-24, Volume: 56, Issue:20 Topics: Drug Discovery; Humans; Molecular Structure; Neglected Diseases; Phenotype; Plasmodium falciparum; Protozoan Infections; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi	2013
Development of the new antimalarial drug pyronaridine: a review. Biomedical and environmental sciences : BES, 1992, Volume: 5, Issue:2 Topics: Administration, Oral; Animals; Antimalarials; Cardiovascular System; Chloroquine; Dogs; Drug Evaluation; Drug Evaluation, Preclinical; Drug Resistance; Drug Therapy, Combination; Haplorhini; Humans; Injections, Intramuscular; Lethal Dose 50; Malaria, Falciparum; Mice; Naphthyridines; Pyrimethamine; Rabbits; Sulfadoxine	1992
Animal Embryotoxicity Studies of Key Non-Artemisinin Antimalarials and Use in Women in the First Trimester. Birth defects research, 2017, Aug-15, Volume: 109, Issue:14 Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Drug Combinations; Female; Humans; Malaria; Malaria, Falciparum; Naphthyridines; Pregnancy; Pregnancy Trimester, First; Pyrimethamine; Quinine; Quinolines; Rabbits; Rats; Sulfadoxine; Teratogens	2017

Trials

2 trial(s) available for pyronaridine and pyrimethamine

Article	Year
Development of the new antimalarial drug pyronaridine: a review. Biomedical and environmental sciences : BES, 1992, Volume: 5, Issue:2 Topics: Administration, Oral; Animals; Antimalarials; Cardiovascular System; Chloroquine; Dogs; Drug Evaluation; Drug Evaluation, Preclinical; Drug Resistance; Drug Therapy, Combination; Haplorhini; Humans; Injections, Intramuscular; Lethal Dose 50; Malaria, Falciparum; Mice; Naphthyridines; Pyrimethamine; Rabbits; Sulfadoxine	1992
[Effects of combined dose of pyronaridine/sulfadoxine/pyrimethamine on falciparum malaria]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 1988, Volume: 6, Issue:4 Topics: Adolescent; Adult; Animals; Antimalarials; Drug Therapy, Combination; Female; Humans; Malaria; Male; Naphthyridines; Plasmodium falciparum; Pyrimethamine; Sulfadoxine	1988

Article

Year

Development of the new antimalarial drug pyronaridine: a review.

Biomedical and environmental sciences : BES, 1992, Volume: 5, Issue:2

Topics: Administration, Oral; Animals; Antimalarials; Cardiovascular System; Chloroquine; Dogs; Drug Evaluation; Drug Evaluation, Preclinical; Drug Resistance; Drug Therapy, Combination; Haplorhini; Humans; Injections, Intramuscular; Lethal Dose 50; Malaria, Falciparum; Mice; Naphthyridines; Pyrimethamine; Rabbits; Sulfadoxine

1992

[Effects of combined dose of pyronaridine/sulfadoxine/pyrimethamine on falciparum malaria].

Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 1988, Volume: 6, Issue:4

Topics: Adolescent; Adult; Animals; Antimalarials; Drug Therapy, Combination; Female; Humans; Malaria; Male; Naphthyridines; Plasmodium falciparum; Pyrimethamine; Sulfadoxine

1988

Other Studies

19 other study(ies) available for pyronaridine and pyrimethamine

Article	Year
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Rotenoids, Flavonoids, and Chalcones from the Root Bark of Millettia usaramensis. Journal of natural products, 2015, Dec-24, Volume: 78, Issue:12 Topics: Antimalarials; Chalcones; Chloroquine; Crystallography, X-Ray; Flavanones; Flavonoids; HEK293 Cells; Humans; Millettia; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Bark; Plant Extracts; Plasmodium falciparum	2015
Antiplasmodial β-triketones from the flowers of the Australian tree Angophora woodsiana. Bioorganic & medicinal chemistry letters, 2017, 06-01, Volume: 27, Issue:11 Topics: Antimalarials; Australia; Cell Survival; Chloroquine; Drug Resistance; Flowers; HEK293 Cells; Humans; Ketones; Magnetic Resonance Spectroscopy; Molecular Conformation; Myrtaceae; Plant Extracts; Plasmodium falciparum; Sesquiterpenes	2017
Pimentelamines A-C, Indole Alkaloids Isolated from the Leaves of the Australian Tree Flindersia pimenteliana. Journal of natural products, 2017, 12-22, Volume: 80, Issue:12 Topics: Antimalarials; Australia; Biological Products; Indole Alkaloids; Magnetic Resonance Spectroscopy; Plant Extracts; Plant Leaves; Plasmodium falciparum; Rutaceae; Trees	2017
Antiplasmodial β-Triketone-Flavanone Hybrids from the Flowers of the Australian Tree Corymbia torelliana. Journal of natural products, 2018, 07-27, Volume: 81, Issue:7 Topics: Antimalarials; Flavanones; Flowers; HEK293 Cells; Humans; Ketones; Magnetic Resonance Spectroscopy; Molecular Structure; Myrtaceae; Plant Extracts; Trees	2018
Hydroxamic Acid Inhibitors Provide Cross-Species Inhibition of Plasmodium M1 and M17 Aminopeptidases. Journal of medicinal chemistry, 2019, 01-24, Volume: 62, Issue:2 Topics: Aminopeptidases; Antimalarials; Binding Sites; Catalytic Domain; Cell Survival; Drug Resistance; HEK293 Cells; Humans; Hydroxamic Acids; Molecular Docking Simulation; Plasmodium; Protease Inhibitors; Protozoan Proteins; Structure-Activity Relationship	2019
Acrotrione: An Oxidized Xanthene from the Roots of Acronychia pubescens. Journal of natural products, 2019, 04-26, Volume: 82, Issue:4 Topics: Oxidation-Reduction; Plant Roots; Rutaceae; Xanthenes	2019
A Meroisoprenoid, Heptenolides, and Journal of natural products, 2020, 02-28, Volume: 83, Issue:2 Topics: Annonaceae; Antimalarials; Flavanones; Flavonoids; HEK293 Cells; Humans; Molecular Structure; Plant Extracts; Plant Leaves; Plasmodium berghei; Plasmodium falciparum	2020
Discovery and development of 2-aminobenzimidazoles as potent antimalarials. European journal of medicinal chemistry, 2021, Oct-05, Volume: 221 Topics: Antimalarials; Benzimidazoles; Dose-Response Relationship, Drug; Drug Discovery; HEK293 Cells; Humans; Malaria, Falciparum; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship	2021
A 5-year surveillance of sensitivity in vivo of Plasmodium falciparum to pyronaridine/sulfadoxine/pyrimethamine in Diaoluo area, Hainan Province. The Southeast Asian journal of tropical medicine and public health, 1991, Volume: 22, Issue:1 Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Child; China; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Middle Aged; Naphthyridines; Plasmodium falciparum; Pyrimethamine; Sulfadoxine	1991
[Combined action of pyronaridine and sulfadoxine/pyrimethamine against Plasmodium berghei ANKA strain in mice]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1990, Volume: 11, Issue:1 Topics: Animals; Antimalarials; Drug Synergism; Drug Therapy, Combination; Female; Malaria; Male; Mice; Naphthyridines; Plasmodium berghei; Pyrimethamine; Sulfadoxine; Sulfanilamides	1990
Antimalarial and toxic effect of triple combination of pyronaridine, sulfadoxine and pyrimethamine. The Southeast Asian journal of tropical medicine and public health, 1989, Volume: 20, Issue:2 Topics: Animals; Antimalarials; Drug Therapy, Combination; Follow-Up Studies; Humans; Malaria; Mice; Naphthyridines; Plasmodium falciparum; Pyrimethamine; Rats; Sulfadoxine; Sulfanilamides	1989
[Delay in emergence of resistance to pyronaridine phosphate in Plasmodium berghei]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1986, Volume: 7, Issue:5 Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Drug Synergism; Mice; Naphthyridines; Plasmodium berghei; Pyrimethamine; Sulfadoxine	1986
[Efficacy of combined use of pyronaridine, sulfadoxine and pyrimethamine in the treatment of falciparum malaria on Hainan Island]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 1988, Volume: 6, Issue:4 Topics: Adolescent; Adult; Animals; Antimalarials; Child; Drug Therapy, Combination; Humans; Malaria; Naphthyridines; Plasmodium falciparum; Pyrimethamine; Sulfadoxine	1988
In vitro activity of pyronaridine against field isolates and reference clones of Plasmodium falciparum. The American journal of tropical medicine and hygiene, 1988, Volume: 38, Issue:1 Topics: Amodiaquine; Animals; Antimalarials; Chemical Phenomena; Chemistry; Chloroquine; Drug Resistance; Humans; Mefloquine; Naphthyridines; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Thailand	1988
[In vitro sensitivity of Plasmodium falciparum to mefloquine, quinine, amodiaquine, chloroquine, pyronaridine and sulfadoxine/pyrimethamine in south Yunnan]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 1994, Volume: 12, Issue:2 Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Mefloquine; Naphthyridines; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine	1994
In vitro susceptibility of Cambodian isolates of Plasmodium falciparum to halofantrine, pyronaridine and artemisinin derivatives. Annals of tropical medicine and parasitology, 1994, Volume: 88, Issue:2 Topics: Adult; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; In Vitro Techniques; Mefloquine; Naphthyridines; Phenanthrenes; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Sesquiterpenes; Triazines	1994
Gametocytocidal activity of pyronaridine and DNA topoisomerase II inhibitors against multidrug-resistant Plasmodium falciparum in vitro. Parasitology international, 2000, Volume: 48, Issue:4 Topics: Amsacrine; Animals; Antimalarials; Chloroquine; Drug Resistance, Multiple; Enzyme Inhibitors; Etoposide; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Naphthyridines; Norfloxacin; Nucleic Acid Synthesis Inhibitors; Plasmodium falciparum; Primaquine; Proguanil; Pyrimethamine; Thailand; Topoisomerase II Inhibitors; Triazines	2000
[Studies on the sensitivity of Plasmodium falciparum to pyronaridine/sulfadoxine/pyrimethamine in vitro]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 2000, Volume: 18, Issue:1 Topics: Animals; Antimalarials; Drug Resistance; Drug Synergism; Naphthyridines; Plasmodium falciparum; Pyrimethamine; Sulfadoxine	2000