Page last updated: 2024-09-02

pyronaridine and piperaquine

pyronaridine has been researched along with piperaquine in 20 studies

Research

Studies (20)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (15.00)	18.7374
1990's	4 (20.00)	18.2507
2000's	1 (5.00)	29.6817
2010's	12 (60.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Anstey, NM; Chalfein, F; Kenangalem, E; Marfurt, J; Piera, KA; Price, RN; Russell, B; Tjitra, E	1
Anstey, NM; Chalfein, F; Ebsworth, EP; Kenangalem, E; Marfurt, J; Piera, KA; Prasetyorini, B; Price, RN; Ratcliff, A; Russell, B; Siswantoro, H; Tjitra, E; Wuwung, M	1
Fidock, DA; Flannery, EL; Winzeler, EA	1
Cao, DQ; Dong, Y; He, H; Liu, DQ; Liu, RJ; Yang, HL; Yang, PF; Zhang, CY	1
Chen, L; Dai, ZR; Fu, DD; Guo, FC; Liao, ZH; Ma, DQ; Ma, ZM; Pang, XJ; Qian, YL	1
Ha, SH; Shao, BR; Zhan, CQ	1
Chen, L; Dai, ZR; Li, CJ; Qian, YL	1
Dong, Y; Liu, D; Liu, R; Yang, H; Yang, P; Zhang, B; Zhang, C	1
Chen, C; Chen, L; Dai, ZR; Ma, ZM; Zheng, XY	1
Fan, B; Huang, Z; Ma, X; Wen, Y; Yang, J; Yang, Z; Zhao, W	1
Feng, XP; Liu, DQ	1
Adjalley, SH; Eappen, AG; Eastman, RT; Ekland, EH; Fidock, DA; Hoffman, SL; Johnston, GL; Lee, MC; Li, T; Richman, A; Sim, BK	1
Basset, D; Benoit-Vical, F; Bourgeois, N; Delaunay, P; Didillon, E; Faugère, B; Malvy, D; Maubon, D; Ménard, G; Oeuvray, C; Parola, P; Pascual, A; Picot, S; Pradines, B; Rogier, C; Simon, F	1
Liu, H; Wang, J; Zhang, CL; Zhou, HN	1
Arzika, I; Fandeur, T; Guillebaud, J; Issaka, M; Maazou, A; Salissou, A; Specht, S; Zamanka, H	1
Amalvict, R; Benoit, N; Briolant, S; Gaillard, T; Madamet, M; Pascual, A; Pradines, B; Travers, D	1
Amalvict, R; Benoit, N; Diatta, B; Diawara, S; Diémé, Y; Fall, B; Fall, M; Gendrot, M; Madamet, M; Nakoulima, A; Pradines, B; Wade, B; Wade, KA	1
Amalvict, R; Benoit, N; Briolant, S; Diatta, B; Diawara, S; Diémé, Y; Fall, B; Fall, M; Gendrot, M; Kounta, MB; Madamet, M; Nakoulima, A; Pradines, B; Wade, B; Wade, KA	1
Clark, RL	1

Reviews

2 review(s) available for pyronaridine and piperaquine

Article	Year
Using genetic methods to define the targets of compounds with antimalarial activity. Journal of medicinal chemistry, 2013, Oct-24, Volume: 56, Issue:20 Topics: Animals; Anopheles; Antimalarials; Drug Resistance; Genetic Association Studies; Genome, Protozoan; Humans; Malaria, Falciparum; Molecular Targeted Therapy; Plasmodium falciparum	2013
Animal Embryotoxicity Studies of Key Non-Artemisinin Antimalarials and Use in Women in the First Trimester. Birth defects research, 2017, Aug-15, Volume: 109, Issue:14 Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Drug Combinations; Female; Humans; Malaria; Malaria, Falciparum; Naphthyridines; Pregnancy; Pregnancy Trimester, First; Pyrimethamine; Quinine; Quinolines; Rabbits; Rats; Sulfadoxine; Teratogens	2017

Article

Year

Using genetic methods to define the targets of compounds with antimalarial activity.

Journal of medicinal chemistry, 2013, Oct-24, Volume: 56, Issue:20

Topics: Animals; Anopheles; Antimalarials; Drug Resistance; Genetic Association Studies; Genome, Protozoan; Humans; Malaria, Falciparum; Molecular Targeted Therapy; Plasmodium falciparum

2013

Animal Embryotoxicity Studies of Key Non-Artemisinin Antimalarials and Use in Women in the First Trimester.

Birth defects research, 2017, Aug-15, Volume: 109, Issue:14

Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Drug Combinations; Female; Humans; Malaria; Malaria, Falciparum; Naphthyridines; Pregnancy; Pregnancy Trimester, First; Pyrimethamine; Quinine; Quinolines; Rabbits; Rats; Sulfadoxine; Teratogens

2017

Trials

2 trial(s) available for pyronaridine and piperaquine

Article	Year
[Observation on the efficacy of combined use of some new antimalarials for the treatment of falciparum malaria in Hainan Province]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 1989, Volume: 7, Issue:2 Topics: Adolescent; Adult; Animals; Antimalarials; Drug Therapy, Combination; Female; Humans; Malaria; Male; Naphthyridines; Plasmodium falciparum; Quinazolines; Quinolines	1989
Pyronaridine-artesunate or dihydroartemisinin-piperaquine versus current first-line therapies for repeated treatment of uncomplicated malaria: a randomised, multicentre, open-label, longitudinal, controlled, phase 3b/4 trial. Lancet (London, England), 2018, 04-07, Volume: 391, Issue:10128 Topics: Adolescent; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Longitudinal Studies; Malaria; Male; Naphthyridines; Quinolines; Young Adult	2018

Article

Year

[Observation on the efficacy of combined use of some new antimalarials for the treatment of falciparum malaria in Hainan Province].

Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 1989, Volume: 7, Issue:2

Topics: Adolescent; Adult; Animals; Antimalarials; Drug Therapy, Combination; Female; Humans; Malaria; Male; Naphthyridines; Plasmodium falciparum; Quinazolines; Quinolines

1989

Pyronaridine-artesunate or dihydroartemisinin-piperaquine versus current first-line therapies for repeated treatment of uncomplicated malaria: a randomised, multicentre, open-label, longitudinal, controlled, phase 3b/4 trial.

Lancet (London, England), 2018, 04-07, Volume: 391, Issue:10128

Topics: Adolescent; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Longitudinal Studies; Malaria; Male; Naphthyridines; Quinolines; Young Adult

2018

Other Studies

16 other study(ies) available for pyronaridine and piperaquine

Article	Year
In vitro activity of pyronaridine against multidrug-resistant Plasmodium falciparum and Plasmodium vivax. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:12 Topics: Animals; Antimalarials; Chloroquine; Drug Resistance, Multiple; Inhibitory Concentration 50; Naphthyridines; Plasmodium falciparum; Plasmodium vivax	2010
In vivo and in vitro efficacy of chloroquine against Plasmodium malariae and P. ovale in Papua, Indonesia. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:1 Topics: Adolescent; Adult; Antimalarials; Child; Child, Preschool; Chloroquine; Female; Humans; Indonesia; Malaria; Male; Middle Aged; Plasmodium malariae; Plasmodium ovale; Treatment Outcome; Young Adult	2011
[Sensitivity in vitro of Plasmodium falciparum to chloroquine, pyronaridine, artesunate and piperaquine in south Yunnan]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 1992, Volume: 10, Issue:3 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Naphthyridines; Plasmodium falciparum; Quinolines; Sesquiterpenes	1992
[Evaluation of the phototoxicity of five antimalarial agents and praziquantel in mice]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1986, Volume: 7, Issue:3 Topics: Animals; Antimalarials; Chloroquine; Female; Male; Mice; Naphthyridines; Photosensitivity Disorders; Praziquantel; Quinacrine; Quinazolines; Quinolines; Ultraviolet Rays	1986
[Suppressive effect of 3 combinations of antimalarials against Plasmodium cynomolgi]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 1987, Volume: 5, Issue:4 Topics: Animals; Antimalarials; Drug Therapy, Combination; Macaca mulatta; Malaria; Naphthyridines; Quinazolines; Quinolines	1987
[Sensitivity of Plasmodium falciparum to seven antimalarials in China-Laos border]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 1995, Volume: 13, Issue:2 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Humans; Naphthyridines; Plasmodium falciparum; Quinolines; Sesquiterpenes	1995
[Studies on residual antimalarial activity of tripynadine in mice and monkeys]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 1993, Volume: 11, Issue:3 Topics: Animals; Antimalarials; Macaca mulatta; Malaria; Mice; Naphthyridines; Plasmodium berghei; Plasmodium cynomolgi; Quinolines	1993
[In vitro sensitivity of Plasmodium falciparum to chloroquine, piperaquine, pyronaridine and artesunate in Yuxi prefecture of Yunnan province]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 1998, Volume: 16, Issue:6 Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Resistance; Female; Humans; In Vitro Techniques; Infant; Inhibitory Concentration 50; Malaria, Falciparum; Male; Middle Aged; Naphthyridines; Plasmodium falciparum; Quinolines; Sesquiterpenes	1998
[Factors affecting the in vitro microtest for drug sensitivity of Plasmodium falciparum]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 2003, Volume: 21, Issue:4 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Blood; Chloroquine; Humans; Malaria, Falciparum; Naphthyridines; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Sesquiterpenes	2003
Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blue. Proceedings of the National Academy of Sciences of the United States of America, 2011, Nov-22, Volume: 108, Issue:47 Topics: Amodiaquine; Animals; Anopheles; Antimalarials; Artemisinins; Blotting, Southern; Dose-Response Relationship, Drug; Ethanolamines; Fluorenes; Genetic Vectors; Germ Cells, Plant; Green Fluorescent Proteins; Luciferases; Lumefantrine; Malaria; Methylene Blue; Naphthyridines; Plasmodium falciparum; Quinolines; Sexual Development	2011
Ex vivo activity of the ACT new components pyronaridine and piperaquine in comparison with conventional ACT drugs against isolates of Plasmodium falciparum. Malaria journal, 2012, Feb-14, Volume: 11 Topics: Africa; Antimalarials; Drug Resistance; Humans; Hypoxanthine; India; Inhibitory Concentration 50; Naphthyridines; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Thailand; Tritium	2012
[In vitro sensitivity of Plasmodium falciparum isolates from China-Myanmar border region to chloroquine, piperaquine and pyronaridine]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 2012, Feb-29, Volume: 30, Issue:1 Topics: Adolescent; Adult; Antimalarials; Child; Child, Preschool; China; Chloroquine; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Myanmar; Naphthyridines; Plasmodium falciparum; Quinolines; Young Adult	2012
Ex vivo responses of Plasmodium falciparum clinical isolates to conventional and new antimalarial drugs in Niger. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:7 Topics: Amodiaquine; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Naphthyridines; Niger; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines	2013
Multinormal in vitro distribution of Plasmodium falciparum susceptibility to piperaquine and pyronaridine. Malaria journal, 2015, Feb-05, Volume: 14 Topics: Africa; Antimalarials; Drug Resistance; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Naphthyridines; Plasmodium falciparum; Quinolines	2015
Absence of Association between Polymorphisms in the RING E3 Ubiquitin Protein Ligase Gene and Ex Vivo Susceptibility to Conventional Antimalarial Drugs in Plasmodium falciparum Isolates from Dakar, Senegal. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:8 Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Doxycycline; Ethanolamines; Fluorenes; Lumefantrine; Mefloquine; Naphthyridines; Plasmodium falciparum; Polymorphism, Genetic; Quinine; Quinolines; Senegal; Ubiquitin-Protein Ligases	2016
Association between Polymorphisms in the Pf Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:3 Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Asparagine; ATP-Binding Cassette Transporters; Chloroquine; Doxycycline; Drug Resistance; Ethanolamines; Fluorenes; Gene Expression; Humans; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Mefloquine; Naphthyridines; Plasmodium falciparum; Polymorphism, Genetic; Protein Isoforms; Protozoan Proteins; Quinine; Quinolines; Repetitive Sequences, Amino Acid; Senegal	2017