Page last updated: 2024-09-02

pyronaridine and artesunic acid

pyronaridine has been researched along with artesunic acid in 43 studies

Research

Studies (43)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (2.33)	18.7374
1990's	4 (9.30)	18.2507
2000's	10 (23.26)	29.6817
2010's	22 (51.16)	24.3611
2020's	6 (13.95)	2.80

Authors

Authors	Studies
Cao, DQ; Dong, Y; He, H; Liu, DQ; Liu, RJ; Yang, HL; Yang, PF; Zhang, CY	1
Huang, WJ; Li, J	1
Dong, Y; Liu, D; Liu, R; Yang, H; Yang, P; Zhang, B; Zhang, C	1
Dong, Y; Huang, KG; Liao, MZ; Liu, DQ; Yang, HL; Yang, PF; Yang, YM; Zhang, CY	1
Ambroise-Thomas, P	1
Fan, B; Huang, Z; Ma, X; Wen, Y; Yang, J; Yang, Z; Zhao, W	1
Gao, BH; Huang, KG; Yang, HL	2
Gao, BL; Yang, HL	1
Jomaa, H; Ortmann, R; Schlitzer, M; Wiesner, J	1
Feng, XP; Liu, DQ	1
Bongard, E; Croft, SL; Peters, W; Rattray, L; Robinson, BL; Stewart, L; Vivas, L	1
Bélard, S; Cisse, B; Fleckenstein, L; Glasenapp, Iv; Issifou, S; Kammer, J; Koumba, PK; Kremsner, PG; Kurth, F; Lell, B; Mordmüller, B; Nemeth, J; Oeuvray, C; Ramharter, M; Schlie, M; Schreier, AC	1
Bélard, S; Kremsner, PG; Kurth, F; Mordmüller, B; Pongratz, P; Ramharter, M	1
Craft, JC; Fleckenstein, L; Jang, IJ; Kirsch, LE; Naik, H; Shin, CS; Tan, B; Yu, KS	1
Nosten, FH	1
Bedu-Addo, G; Bhatt, KM; Borghini-Fuhrer, I; Bustos, DG; Duparc, S; Fleckenstein, L; Gaye, O; Kayentao, K; Sesay, SS; Shin, CS; Thompson, R; Tjitra, E; Tshefu, AK	1
Nau, JY	1
Borghini-Fuhrer, I; Duparc, S; Fleckenstein, L; Poravuth, Y; Purnama, A; Pyae Phyo, A; Rao, BH; Rueangweerayut, R; Shin, CS; Socheat, D; Tjitra, E; Uthaisin, C; Valecha, N	1
Borghini-Fuhrer, I; Duparc, S; Fleckenstein, L; Jung, D; Lopez-Lazaro, L; Methaneethorn, J; Morris, CA; Pokorny, R; Shin, CS	1
Abdulla, S; Binh, TQ; Borghini-Fuhrer, I; Duparc, S; Fleckenstein, L; Pénali, LK; Phyo, AP; Poravuth, Y; Rueangweerayut, R; Shin, CS; Tien, NT; Tinto, H; Uthaisin, C; Valecha, N	1
Holtermann, MK	1
Bhatt, KM; Borghini-Fuhrer, I; Bustos, MD; de Salazar, PM; Doumbo, OK; Duparc, S; Fleckenstein, L; Kayentao, K; Kimani, J; Kokolomami, JH; Offianan, AT; Ouédraogo, A; Pénali, LK; Quicho, F; Ramharter, M; Shin, CS; Tiono, AB; Tshefu, AK	1
Arbe-Barnes, S; Borghini-Fuhrer, I; Craft, CJ; Duparc, S; Fleckenstein, L; Miller, RM; Shin, CS	1
Cremers, S; Fidock, DA; Henrich, PP; Kyle, DE; O'Brien, C; Sáenz, FE	1
Bukirwa, H; Kramer, CV; Nair, S; Sinclair, D; Tharyan, P; Unnikrishnan, B	1
Arbe-Barnes, S; Borghini-Fuhrer, I; Duparc, S; Fleckenstein, L; Lopez-Lazaro, L; Miller, RM; Morris, CA; Pokorny, R; Shin, JS	1
Ashley, EA; Blessborn, D; Chairat, K; Day, NP; Hanboonkunupakarn, B; Jittamala, P; Lee, SJ; Nosten, F; Panapipat, S; Pukrittayakamee, S; Tarning, J; Thana, P; White, NJ	1
Beavogui, AH; Bjorkman, A; Borghini-Fuhrer, I; Borrmann, S; Camara, D; Compaore, YD; Coulibaly, AS; Dara, N; Diallo, MS; Dicko, A; Djimdé, AA; Doumbo, OK; Duparc, S; Fofana, B; Gil, JP; Kabore, MJ; Miller, RM; Nikiema, F; Ouedraogo, JB; Sagara, I; Shin, J; Sirima, SB; Somé, AF; Soulama, I; Sylla, MM; Thera, I; Traore, OB; Zongo, I	1
Ayyoub, A; Borghini-Fuhrer, I; Djimde, AA; Duparc, S; Fleckenstein, L; Methaneethorn, J; Ramharter, M; Shin, JS; Tekete, M	1
Borghini Fuhrer, I; Canavati, SE; Denis, MB; Dondorp, AM; Duparc, S; Heng, P; Huy, R; Khim, N; Kim, S; Leang, R; Menard, D; Ringwald, P; Tol, B; Vestergaard, LS	1
Amalvict, R; Benoit, N; Diatta, B; Diawara, S; Diémé, Y; Fall, B; Fall, M; Gendrot, M; Madamet, M; Nakoulima, A; Pradines, B; Wade, B; Wade, KA	1
Amalvict, R; Benoit, N; Briolant, S; Diatta, B; Diawara, S; Diémé, Y; Fall, B; Fall, M; Gendrot, M; Kounta, MB; Madamet, M; Nakoulima, A; Pradines, B; Wade, B; Wade, KA	1
Choy, F; Makio, N; Mens, P; Okach, S; Omweri, G; Osoti, V; Roth, JM; Sawa, P; Schallig, HDFH	1
Bousema, T; Bradley, J; Makio, N; Mens, PF; Omweri, G; Osoti, V; Roth, JM; Sawa, P; Schallig, HDFH	1
Hine, P; Pryce, J	1
Fidock, DA; Okombo, J	1
Bustos, MD; Cong Tran, D; Hong Huynh, Q; Khim, N; Quang Bui, P; Quang Nguyen, T; Ringwald, P; Thanh Le, D; Thanh Tran, D; Thi Ta, T; Van Truong, H; Witkowski, B	1
Augustin, Y; Kamarulzaman, A; Kremsner, P; Krishna, S; Platteeuw, H; Sall, A; Staines, HM; Wang, J; Xu, C	1
Bailly, C	1
Held, J; Hoffmann, W; Koehne, E; Kreidenweiss, A; Kremsner, PG; Mombo-Ngoma, G; Ramharter, M; Rodi, M; Zander, N; Zoleko-Manego, R	1
Tsanni, A	1

Reviews

6 review(s) available for pyronaridine and artesunic acid

Article	Year
[Treatment of malaria: prevention of resistance by combinations of antimalarial agents]. Medecine tropicale : revue du Corps de sante colonial, 2000, Volume: 60, Issue:3 Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Naphthyridines; Plasmodium; Sesquiterpenes	2000
New antimalarial drugs. Angewandte Chemie (International ed. in English), 2003, Nov-10, Volume: 42, Issue:43 Topics: Aminoquinolines; Animals; Antimalarials; Artemisinins; Artesunate; Atovaquone; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Design; Drug Resistance; Ethanolamines; Flavonoids; Fluorenes; Fosfomycin; Global Health; Humans; Lumefantrine; Malaria; Naphthoquinones; Naphthyridines; Plasmodium falciparum; Proguanil; Sesquiterpenes	2003
Artesunate plus pyronaridine for treating uncomplicated Plasmodium falciparum malaria. The Cochrane database of systematic reviews, 2014, Mar-04, Issue:3 Topics: Adult; Antimalarials; Artemisinins; Artesunate; Child; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Liver; Lumefantrine; Malaria, Falciparum; Mefloquine; Naphthyridines; Randomized Controlled Trials as Topic	2014
Pyronaridine-artesunate for treating uncomplicated Plasmodium falciparum malaria. The Cochrane database of systematic reviews, 2019, 01-08, Volume: 1 Topics: Adult; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Drug Combinations; Drug Therapy, Combination; Humans; Liver; Lumefantrine; Malaria, Falciparum; Mefloquine; Naphthyridines; Randomized Controlled Trials as Topic	2019
Repurposing Antimalarials to Tackle the COVID-19 Pandemic. Trends in parasitology, 2021, Volume: 37, Issue:1 Topics: Antimalarials; Antiviral Agents; Artemisinins; Artesunate; COVID-19 Drug Treatment; Cytokine Release Syndrome; Drug Combinations; Drug Repositioning; Humans; Naphthyridines; SARS-CoV-2	2021
Pyronaridine: An update of its pharmacological activities and mechanisms of action. Biopolymers, 2021, Volume: 112, Issue:4 Topics: Animals; Antimalarials; Artesunate; Humans; Malaria, Falciparum; Naphthyridines; Plasmodium falciparum	2021

Trials

14 trial(s) available for pyronaridine and artesunic acid

Article	Year
Population pharmacokinetics of artesunate and dihydroartemisinin following single- and multiple-dosing of oral artesunate in healthy subjects. Malaria journal, 2009, Dec-18, Volume: 8 Topics: Administration, Oral; Adult; Antimalarials; Artemisinins; Artesunate; Chromatography, Liquid; Eating; Female; Humans; Male; Mass Spectrometry; Models, Statistical; Naphthyridines; Plasma; Republic of Korea; Young Adult	2009
Efficacy and safety of a fixed-dose oral combination of pyronaridine-artesunate compared with artemether-lumefantrine in children and adults with uncomplicated Plasmodium falciparum malaria: a randomised non-inferiority trial. Lancet (London, England), 2010, Apr-24, Volume: 375, Issue:9724 Topics: Adolescent; Adult; Africa; Antimalarials; Artemether; Artemisinins; Artesunate; Asia; Child; Child, Preschool; Double-Blind Method; Drug Combinations; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Male; Middle Aged; Naphthyridines; Treatment Outcome; Young Adult	2010
Pyronaridine-artesunate versus chloroquine in patients with acute Plasmodium vivax malaria: a randomized, double-blind, non-inferiority trial. PloS one, 2011, Jan-18, Volume: 6, Issue:1 Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Female; Fever; Humans; Malaria, Vivax; Male; Middle Aged; Naphthyridines; Time Factors; Treatment Outcome; Young Adult	2011
Drug-drug interaction analysis of pyronaridine/artesunate and ritonavir in healthy volunteers. The American journal of tropical medicine and hygiene, 2012, Volume: 86, Issue:3 Topics: Adolescent; Adult; Antimalarials; Area Under Curve; Artemisinins; Artesunate; Drug Interactions; Female; HIV Protease Inhibitors; Humans; Male; Middle Aged; Naphthyridines; Ritonavir; Young Adult	2012
Pyronaridine-artesunate versus mefloquine plus artesunate for malaria. The New England journal of medicine, 2012, Apr-05, Volume: 366, Issue:14 Topics: Adolescent; Adult; Africa; Antimalarials; Artemisinins; Artesunate; Asia; Child; Child, Preschool; Drug Combinations; Drug Resistance; Female; Humans; Intention to Treat Analysis; Kaplan-Meier Estimate; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Naphthyridines; Proportional Hazards Models; Young Adult	2012
Pyronaridine-artesunate granules versus artemether-lumefantrine crushed tablets in children with Plasmodium falciparum malaria: a randomized controlled trial. Malaria journal, 2012, Oct-31, Volume: 11 Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Child; Child, Preschool; Dosage Forms; Drug Combinations; Ethanolamines; Female; Fluorenes; Humans; Infant; Malaria, Falciparum; Male; Naphthyridines; Parasite Load; Recurrence; Tablets; Treatment Outcome	2012
Pharmacokinetic interaction between pyronaridine-artesunate and metoprolol. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:10 Topics: Adolescent; Adult; Alanine Transaminase; Antimalarials; Artemisinins; Artesunate; Aspartate Aminotransferases; Female; Humans; Male; Metoprolol; Middle Aged; Naphthyridines; Young Adult	2014
Pharmacokinetic interactions between primaquine and pyronaridine-artesunate in healthy adult Thai subjects. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:1 Topics: Administration, Oral; Adult; Antimalarials; Artemisinins; Artesunate; Cross-Over Studies; Drug Interactions; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Naphthyridines; Primaquine; Thailand; Young Adult	2015
Safety and efficacy of re-treatments with pyronaridine-artesunate in African patients with malaria: a substudy of the WANECAM randomised trial. The Lancet. Infectious diseases, 2016, Volume: 16, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Artesunate; Burkina Faso; Child; Child, Preschool; Drug Combinations; Female; Guinea; Humans; Infant; Malaria; Male; Mali; Middle Aged; Naphthyridines; Plasmodium; Retreatment; Treatment Outcome; Young Adult	2016
Population Pharmacokinetics of Pyronaridine in Pediatric Malaria Patients. Antimicrobial agents and chemotherapy, 2015, Dec-14, Volume: 60, Issue:3 Topics: Adolescent; Antimalarials; Area Under Curve; Artemisinins; Artesunate; Child; Child, Preschool; Female; Humans; Infant; Malaria; Malaria, Falciparum; Malaria, Vivax; Male; Models, Theoretical; Naphthyridines	2015
Pyronaridine-artesunate or dihydroartemisinin-piperaquine versus current first-line therapies for repeated treatment of uncomplicated malaria: a randomised, multicentre, open-label, longitudinal, controlled, phase 3b/4 trial. Lancet (London, England), 2018, 04-07, Volume: 391, Issue:10128 Topics: Adolescent; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Longitudinal Studies; Malaria; Male; Naphthyridines; Quinolines; Young Adult	2018
Pyronaridine-artesunate and artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Kenyan children: a randomized controlled non-inferiority trial. Malaria journal, 2018, May-15, Volume: 17, Issue:1 Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artesunate; Child; Child, Preschool; Female; Humans; Infant; Kenya; Malaria, Falciparum; Male; Naphthyridines	2018
Plasmodium falciparum gametocyte dynamics after pyronaridine-artesunate or artemether-lumefantrine treatment. Malaria journal, 2018, Jun-04, Volume: 17, Issue:1 Topics: Adolescent; Antimalarials; Artemether, Lumefantrine Drug Combination; Artesunate; Child; Child, Preschool; Female; Humans; Infant; Kenya; Malaria, Falciparum; Male; Naphthyridines; Plasmodium falciparum; Reverse Transcriptase Polymerase Chain Reaction; Self-Sustained Sequence Replication	2018
Pyronaridine-artesunate Efficacy and Safety in Uncomplicated Plasmodium falciparum Malaria in Areas of Artemisinin-resistant Falciparum in Viet Nam (2017-2018). Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020, 05-06, Volume: 70, Issue:10 Topics: Adult; Antimalarials; Artemisinins; Artesunate; Child; Drug Combinations; Humans; Malaria, Falciparum; Naphthyridines; Plasmodium falciparum; Prospective Studies; Vietnam	2020

Other Studies

23 other study(ies) available for pyronaridine and artesunic acid

Article	Year
[Sensitivity in vitro of Plasmodium falciparum to chloroquine, pyronaridine, artesunate and piperaquine in south Yunnan]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 1992, Volume: 10, Issue:3 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Naphthyridines; Plasmodium falciparum; Quinolines; Sesquiterpenes	1992
[Effects of artesunate, pyronaridine and hydroxypiperaquine on chloroquine-sensitive and chloroquine-resistant isolates of Plasmodium falciparum in vitro]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1988, Volume: 9, Issue:1 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Naphthyridines; Plasmodium falciparum; Quinolines; Sesquiterpenes	1988
[Sensitivity of Plasmodium falciparum to seven antimalarials in China-Laos border]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 1995, Volume: 13, Issue:2 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Humans; Naphthyridines; Plasmodium falciparum; Quinolines; Sesquiterpenes	1995
In vitro sensitivity of Plasmodium falciparum to eight antimalarials in China-Myanmar and China-Lao PDR border areas. The Southeast Asian journal of tropical medicine and public health, 1997, Volume: 28, Issue:3 Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; China; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Humans; Laos; Microbial Sensitivity Tests; Myanmar; Naphthyridines; Plasmodium falciparum; Quinine; Sesquiterpenes	1997
[In vitro sensitivity of Plasmodium falciparum to chloroquine, piperaquine, pyronaridine and artesunate in Yuxi prefecture of Yunnan province]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 1998, Volume: 16, Issue:6 Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Resistance; Female; Humans; In Vitro Techniques; Infant; Inhibitory Concentration 50; Malaria, Falciparum; Male; Middle Aged; Naphthyridines; Plasmodium falciparum; Quinolines; Sesquiterpenes	1998
[Effect of pyronaridine, mefloquine and quinine on artesunate-sensitive and artesunate-resistant Plasmodium falciparum]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 2000, Volume: 18, Issue:1 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Drug Resistance; Drug Synergism; Mefloquine; Naphthyridines; Plasmodium falciparum; Quinine; Sesquiterpenes	2000
[In vitro response of Plasmodium falciparum FCC1/HN to artesunate, pyronaridine and other antimalarials]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 2002, Volume: 20, Issue:2 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Drug Resistance; Naphthyridines; Plasmodium falciparum; Sesquiterpenes	2002
[Monitoring of sensitivity of artesunate-resistant Plasmodium falciparum to pyronaridine]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 2000, Volume: 18, Issue:5 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Drug Resistance; Naphthyridines; Plasmodium falciparum; Sesquiterpenes	2000
[Factors affecting the in vitro microtest for drug sensitivity of Plasmodium falciparum]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 2003, Volume: 21, Issue:4 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Blood; Chloroquine; Humans; Malaria, Falciparum; Naphthyridines; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Sesquiterpenes	2003
Anti-malarial efficacy of pyronaridine and artesunate in combination in vitro and in vivo. Acta tropica, 2008, Volume: 105, Issue:3 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Drug Resistance, Multiple; Drug Therapy, Combination; In Vitro Techniques; Inhibitory Concentration 50; Malaria; Mice; Naphthyridines; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Sesquiterpenes; Treatment Outcome	2008
Fixed-dose pyronaridine-artesunate combination for treatment of uncomplicated falciparum malaria in pediatric patients in Gabon. The Journal of infectious diseases, 2008, Sep-15, Volume: 198, Issue:6 Topics: Adolescent; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug Tolerance; Female; Gabon; Humans; Malaria, Falciparum; Male; Naphthyridines; Plasmodium falciparum; Polymerase Chain Reaction; Safety; Treatment Outcome	2008
In vitro activity of pyronaridine against Plasmodium falciparum and comparative evaluation of anti-malarial drug susceptibility assays. Malaria journal, 2009, Apr-23, Volume: 8 Topics: Administration, Oral; Adolescent; Animals; Antigens, Protozoan; Antimalarials; Artemisinins; Artesunate; Biological Assay; Child; Child, Preschool; Chloroquine; Drug Evaluation, Preclinical; Enzyme-Linked Immunosorbent Assay; Female; Gabon; Humans; Infant; Malaria, Falciparum; Male; Naphthyridines; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Proteins; Quinine; Regression Analysis	2009
Pyronaridine-artesunate for uncomplicated falciparum malaria. Lancet (London, England), 2010, Apr-24, Volume: 375, Issue:9724 Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Drug Combinations; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Naphthyridines	2010
[A new antimalarial drug combination]. Revue medicale suisse, 2010, May-05, Volume: 6, Issue:247 Topics: Antimalarials; Artemisinins; Artesunate; Drug Combinations; Humans; Malaria, Falciparum; Naphthyridines; Plasmodium falciparum; Treatment Outcome	2010
[New combination therapy against malaria]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2012, Aug-21, Volume: 132, Issue:15 Topics: Africa; Antimalarials; Artemisinins; Artesunate; Asia; Drug Combinations; Drug Resistance; Global Health; Humans; Malaria, Falciparum; Mefloquine; Naphthyridines	2012
Safety and efficacy of pyronaridine-artesunate in uncomplicated acute malaria: an integrated analysis of individual patient data from six randomized clinical trials. Malaria journal, 2013, Feb-21, Volume: 12 Topics: Adolescent; Adult; Africa; Antimalarials; Artemisinins; Artesunate; Asia; Child; Child, Preschool; Clinical Trials, Phase III as Topic; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Infant; Malaria; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Naphthyridines; Randomized Controlled Trials as Topic; Treatment Outcome; Young Adult	2013
Evidence for pyronaridine as a highly effective partner drug for treatment of artemisinin-resistant malaria in a rodent model. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:1 Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Drug Combinations; Drug Resistance; Female; Flow Cytometry; Malaria, Falciparum; Mefloquine; Mice; Naphthyridines	2014
Efficacy and Safety of Pyronaridine-Artesunate for Treatment of Uncomplicated Plasmodium falciparum Malaria in Western Cambodia. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:7 Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Cambodia; Child; Female; Humans; Kaplan-Meier Estimate; Malaria, Falciparum; Male; Middle Aged; Naphthyridines; Young Adult	2016
Absence of Association between Polymorphisms in the RING E3 Ubiquitin Protein Ligase Gene and Ex Vivo Susceptibility to Conventional Antimalarial Drugs in Plasmodium falciparum Isolates from Dakar, Senegal. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:8 Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Doxycycline; Ethanolamines; Fluorenes; Lumefantrine; Mefloquine; Naphthyridines; Plasmodium falciparum; Polymorphism, Genetic; Quinine; Quinolines; Senegal; Ubiquitin-Protein Ligases	2016
Association between Polymorphisms in the Pf Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:3 Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Asparagine; ATP-Binding Cassette Transporters; Chloroquine; Doxycycline; Drug Resistance; Ethanolamines; Fluorenes; Gene Expression; Humans; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Mefloquine; Naphthyridines; Plasmodium falciparum; Polymorphism, Genetic; Protein Isoforms; Protozoan Proteins; Quinine; Quinolines; Repetitive Sequences, Amino Acid; Senegal	2017
Pyronaridine-artesunate Shows Promise as an Effective and Well-tolerated Treatment for Artemisinin-resistant Plasmodium falciparum Malaria. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020, 05-06, Volume: 70, Issue:10 Topics: Artemisinins; Artesunate; Humans; Malaria, Falciparum; Naphthyridines; Vietnam	2020
Evidence for in vitro and in vivo activity of the antimalarial pyronaridine against Schistosoma. PLoS neglected tropical diseases, 2021, Volume: 15, Issue:6 Topics: Animals; Antimalarials; Antiprotozoal Agents; Artesunate; Child; Drug Combinations; Gabon; Humans; Larva; Methylene Blue; Mice; Naphthyridines; Schistosoma haematobium; Schistosoma mansoni; Schistosomiasis haematobia; Schistosomiasis mansoni	2021
African scientists race to test COVID drugs - but face major hurdles. Nature, 2021, Volume: 599, Issue:7883 Topics: Africa; Amides; Amodiaquine; Artesunate; Atazanavir Sulfate; Carbamates; Clinical Trials as Topic; COVID-19; COVID-19 Drug Treatment; COVID-19 Vaccines; Cytidine; Drug Approval; Drug Evaluation, Preclinical; Drug Repositioning; Drug Therapy, Combination; Humans; Hydroxylamines; Imidazoles; Ivermectin; Naphthyridines; Nitro Compounds; Pregnenediones; Pyrazines; Pyrrolidines; Ritonavir; Sample Size; Thiazoles; Valine; World Health Organization	2021