Page last updated: 2024-09-02

pyronaridine and artesunate

pyronaridine has been researched along with artesunate in 20 studies

Research

Studies (20)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	14 (70.00)	24.3611
2020's	6 (30.00)	2.80

Authors

Authors	Studies
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Anstey, NM; Chalfein, F; Kenangalem, E; Marfurt, J; Piera, KA; Price, RN; Russell, B; Tjitra, E	1
Anstey, NM; Chalfein, F; Ebsworth, EP; Kenangalem, E; Marfurt, J; Piera, KA; Prasetyorini, B; Price, RN; Ratcliff, A; Russell, B; Siswantoro, H; Tjitra, E; Wuwung, M	1
Fidock, DA; Flannery, EL; Winzeler, EA	1
Avery, VM; Sykes, ML	1
Andrews, KT; Avery, VM; Duffy, S; Hamacher, A; Hansen, FK; Kassack, MU; Kuna, K; Kurz, T; Marek, L; Meister, S; Mordmüller, B; Schmetter, R; Stenzel, K; Sumanadasa, SD; Winzeler, EA	1
Avery, V; Derese, S; Deyou, T; Duffy, S; Erdélyi, M; Fitzpatrick, PA; Gruhonjic, A; Gumula, I; Heydenreich, M; Holleran, J; Landberg, G; Mumo, M; Pang, F; Rissanen, K; Yenesew, A	1
Avery, VM; Baell, JB; Bullen, HE; Cowman, AF; Crabb, BS; Curtis, JM; Di Rago, AE; Duffy, S; Gilson, PR; Hutton, CA; Jarman, KE; Jousset Subroux, H; Lowes, KN; Nguyen, W; Prinz, B; Sleebs, BE; Tan, C	1
Avery, VM; Carroll, AR; Duffy, S; Senadeera, SPD	1
Avery, VM; Carroll, AR; Duffy, S; Robertson, LP; Wang, D; Wang, Y	1
Avery, VM; Carroll, AR; Duffy, S; Lucantoni, L; Senadeera, SPD	1
Andrews, KT; Antonova-Koch, Y; Avery, VM; Diedrich, D; Duffy, S; Fisher, G; Gebru, T; Hansen, FK; Held, J; Hesping, E; Kurz, T; Meister, S; Schöler, A; Stenzel, K; Winzeler, EA	1
Avery, VM; Butler, GS; Drinkwater, N; Duffy, S; Grin, PM; Kassiou, M; Lucantoni, L; Malcolm, TR; McGowan, S; Overall, CM; Scammells, PJ; Vinh, NB	1
Avery, VM; Carroll, AR; Duffy, S; Lucantoni, L; Robertson, LP	1
Avery, VM; Duffy, S; Erdélyi, M; Lindblad, S; Maeda, G; Munissi, JJE; Nyandoro, SS; Pelletier, J	1
Ekins, S; Lane, TR	1
Avery, VM; Dans, MG; de Koning-Ward, TF; Duffy, S; Gancheva, MR; Gilson, PR; Lowes, KN; Ngo, A; Nguyen, W; Romeo, O; Sabroux, HJ; Sleebs, BE; Wilson, DW	1
Baum, J; Bridgford, JL; Charman, SA; Churchyard, A; Crespo, B; Deni, I; Fidock, DA; Gahalawat, S; Gamo, FJ; Laleu, B; Lawong, A; Mittal, N; Mok, S; Niederstrasser, H; Okombo, J; Palmer, MJ; Phillips, MA; Posner, B; Ready, JM; Striepen, J; Winzeler, E; Wittlin, S; Yeo, T; Zhou, A	1
Avery, VM; Challis, MP; Creek, DJ; De Paoli, A; Devine, SM; Kigotho, JK; MacRaild, CA; Norton, RS; Scammells, PJ; Siddiqui, G	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1

Reviews

2 review(s) available for pyronaridine and artesunate

Article	Year
Using genetic methods to define the targets of compounds with antimalarial activity. Journal of medicinal chemistry, 2013, Oct-24, Volume: 56, Issue:20 Topics: Animals; Anopheles; Antimalarials; Drug Resistance; Genetic Association Studies; Genome, Protozoan; Humans; Malaria, Falciparum; Molecular Targeted Therapy; Plasmodium falciparum	2013
Approaches to protozoan drug discovery: phenotypic screening. Journal of medicinal chemistry, 2013, Oct-24, Volume: 56, Issue:20 Topics: Drug Discovery; Humans; Molecular Structure; Neglected Diseases; Phenotype; Plasmodium falciparum; Protozoan Infections; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi	2013

Other Studies

18 other study(ies) available for pyronaridine and artesunate

Article	Year
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
In vitro activity of pyronaridine against multidrug-resistant Plasmodium falciparum and Plasmodium vivax. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:12 Topics: Animals; Antimalarials; Chloroquine; Drug Resistance, Multiple; Inhibitory Concentration 50; Naphthyridines; Plasmodium falciparum; Plasmodium vivax	2010
In vivo and in vitro efficacy of chloroquine against Plasmodium malariae and P. ovale in Papua, Indonesia. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:1 Topics: Adolescent; Adult; Antimalarials; Child; Child, Preschool; Chloroquine; Female; Humans; Indonesia; Malaria; Male; Middle Aged; Plasmodium malariae; Plasmodium ovale; Treatment Outcome; Young Adult	2011
Discovery of HDAC inhibitors with potent activity against multiple malaria parasite life cycle stages. European journal of medicinal chemistry, 2014, Jul-23, Volume: 82 Topics: Antimalarials; Dose-Response Relationship, Drug; Drug Discovery; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Repressor Proteins; Structure-Activity Relationship	2014
Rotenoids, Flavonoids, and Chalcones from the Root Bark of Millettia usaramensis. Journal of natural products, 2015, Dec-24, Volume: 78, Issue:12 Topics: Antimalarials; Chalcones; Chloroquine; Crystallography, X-Ray; Flavanones; Flavonoids; HEK293 Cells; Humans; Millettia; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Bark; Plant Extracts; Plasmodium falciparum	2015
Optimization of 2-Anilino 4-Amino Substituted Quinazolines into Potent Antimalarial Agents with Oral in Vivo Activity. Journal of medicinal chemistry, 2017, 02-09, Volume: 60, Issue:3 Topics: Administration, Oral; Animals; Antimalarials; Disease Models, Animal; Mice; Plasmodium falciparum; Quinazolines; Structure-Activity Relationship	2017
Antiplasmodial β-triketones from the flowers of the Australian tree Angophora woodsiana. Bioorganic & medicinal chemistry letters, 2017, 06-01, Volume: 27, Issue:11 Topics: Antimalarials; Australia; Cell Survival; Chloroquine; Drug Resistance; Flowers; HEK293 Cells; Humans; Ketones; Magnetic Resonance Spectroscopy; Molecular Conformation; Myrtaceae; Plant Extracts; Plasmodium falciparum; Sesquiterpenes	2017
Pimentelamines A-C, Indole Alkaloids Isolated from the Leaves of the Australian Tree Flindersia pimenteliana. Journal of natural products, 2017, 12-22, Volume: 80, Issue:12 Topics: Antimalarials; Australia; Biological Products; Indole Alkaloids; Magnetic Resonance Spectroscopy; Plant Extracts; Plant Leaves; Plasmodium falciparum; Rutaceae; Trees	2017
Antiplasmodial β-Triketone-Flavanone Hybrids from the Flowers of the Australian Tree Corymbia torelliana. Journal of natural products, 2018, 07-27, Volume: 81, Issue:7 Topics: Antimalarials; Flavanones; Flowers; HEK293 Cells; Humans; Ketones; Magnetic Resonance Spectroscopy; Molecular Structure; Myrtaceae; Plant Extracts; Trees	2018
One-pot, multi-component synthesis and structure-activity relationships of peptoid-based histone deacetylase (HDAC) inhibitors targeting malaria parasites. European journal of medicinal chemistry, 2018, Oct-05, Volume: 158 Topics: Acetylation; Antimalarials; Hep G2 Cells; Histone Deacetylase Inhibitors; Histones; Humans; Malaria, Falciparum; Peptoids; Plasmodium falciparum; Protozoan Proteins	2018
Hydroxamic Acid Inhibitors Provide Cross-Species Inhibition of Plasmodium M1 and M17 Aminopeptidases. Journal of medicinal chemistry, 2019, 01-24, Volume: 62, Issue:2 Topics: Aminopeptidases; Antimalarials; Binding Sites; Catalytic Domain; Cell Survival; Drug Resistance; HEK293 Cells; Humans; Hydroxamic Acids; Molecular Docking Simulation; Plasmodium; Protease Inhibitors; Protozoan Proteins; Structure-Activity Relationship	2019
Acrotrione: An Oxidized Xanthene from the Roots of Acronychia pubescens. Journal of natural products, 2019, 04-26, Volume: 82, Issue:4 Topics: Oxidation-Reduction; Plant Roots; Rutaceae; Xanthenes	2019
A Meroisoprenoid, Heptenolides, and Journal of natural products, 2020, 02-28, Volume: 83, Issue:2 Topics: Annonaceae; Antimalarials; Flavanones; Flavonoids; HEK293 Cells; Humans; Molecular Structure; Plant Extracts; Plant Leaves; Plasmodium berghei; Plasmodium falciparum	2020
Toward the Target: Tilorone, Quinacrine, and Pyronaridine Bind to Ebola Virus Glycoprotein. ACS medicinal chemistry letters, 2020, Aug-13, Volume: 11, Issue:8 Topics:	2020
Structure activity refinement of phenylsulfonyl piperazines as antimalarials that block erythrocytic invasion. European journal of medicinal chemistry, 2021, Mar-15, Volume: 214 Topics: Animals; Antimalarials; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Erythrocytes; Hep G2 Cells; Humans; Malaria, Falciparum; Mice; Microsomes, Liver; Molecular Structure; Parasitic Sensitivity Tests; Piperazines; Plasmodium falciparum; Plasmodium knowlesi; Solubility; Structure-Activity Relationship	2021
Novel Antimalarial Tetrazoles and Amides Active against the Hemoglobin Degradation Pathway in Journal of medicinal chemistry, 2021, 03-11, Volume: 64, Issue:5 Topics: Amides; Antimalarials; Drug Resistance, Microbial; Hemeproteins; Hemoglobins; Hep G2 Cells; Humans; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Small Molecule Libraries; Structure-Activity Relationship; Tetrazoles	2021
Discovery and development of 2-aminobenzimidazoles as potent antimalarials. European journal of medicinal chemistry, 2021, Oct-05, Volume: 221 Topics: Antimalarials; Benzimidazoles; Dose-Response Relationship, Drug; Drug Discovery; HEK293 Cells; Humans; Malaria, Falciparum; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship	2021
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023