pyroglutamylleucine has been researched along with pyrrolidonecarboxylic acid in 7 studies
*Pyrrolidonecarboxylic Acid: A cyclized derivative of L-GLUTAMIC ACID. Elevated blood levels may be associated with problems of GLUTAMINE or GLUTATHIONE metabolism. [MeSH]
*Pyrrolidonecarboxylic Acid: A cyclized derivative of L-GLUTAMIC ACID. Elevated blood levels may be associated with problems of GLUTAMINE or GLUTATHIONE metabolism. [MeSH]
| Studies (pyroglutamylleucine) | Trials (pyroglutamylleucine) | Recent Studies (post-2010) (pyroglutamylleucine) | Studies (pyrrolidonecarboxylic acid) | Trials (pyrrolidonecarboxylic acid) | Recent Studies (post-2010) (pyrrolidonecarboxylic acid) |
|---|---|---|---|---|---|
| 7 | 0 | 6 | 3,005 | 101 | 671 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (85.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baláspiri, L; Kovács, GL; Szontágh, L; Telegdy, G | 1 |
| Egashira, Y; Furuta, S; Hashimoto, K; Itabashi, M; Kiyono, T; Mochizuki, S; Nagata, M; Nakamura, Y; Ono, S; Park, EY; Sakata, Y; Sanada, H; Sato, K; Shimmura, Y; Suzuki, Y | 1 |
| Aoi, W; Bou, Y; Fujiwara, M; Kiyono, T; Naito, Y; Ohta, R; Park, EY; Sato, K; Takagi, T; Wada, E; Wada, S; Yoshikawa, T | 1 |
| Hirooka, K; Kimura, S; Kiyono, T; Kuniishi, S; Nakamura, Y; Ohtsuka, M; Park, EY; Sato, K; Yamamoto, Y | 1 |
| Egashira, Y; Hirai, S; Horii, S; Matsuzaki, Y; Ono, S; Sato, K; Shimmura, Y | 1 |
| Kaibori, M; Kiyono, T; Kon, M; Miki, H; Nakatake, R; Nishizawa, M; Oishi, M; Okumura, T; Sato, K; Tanaka, Y; Tokuhara, K | 1 |
| Fukutomi, R; Kanamoto, R; Mizushige, T; Mori, Y; Ohinata, K; Shimmura, Y; Yamamoto, Y | 1 |
7 other study(ies) available for pyroglutamylleucine and pyrrolidonecarboxylic acid
| Article | Year |
|---|---|
Dipeptides delay the onset of morphine withdrawal in the mouse.
Topics: Analysis of Variance; Animals; Dipeptides; Humans; Male; Mice; Morphine; Morphine Dependence; Naloxone; Pyrrolidonecarboxylic Acid; Substance Withdrawal Syndrome | 1984 |
Identification of a hepatoprotective peptide in wheat gluten hydrolysate against D-galactosamine-induced acute hepatitis in rats.
Topics: Animals; Biomarkers; Dipeptides; Disease Models, Animal; Galactosamine; Glutens; Hepatitis; Peptide Fragments; Protective Agents; Protein Hydrolysates; Pyrrolidonecarboxylic Acid; Rats; Triticum | 2013 |
Ingestion of low dose pyroglutamyl leucine improves dextran sulfate sodium-induced colitis and intestinal microbiota in mice.
Topics: Animals; Anti-Inflammatory Agents; Colitis; Dextran Sulfate; Dipeptides; Disease Models, Animal; Humans; Intestines; Male; Mice; Mice, Inbred C57BL; Microbiota; Pyrrolidonecarboxylic Acid | 2013 |
Identification of pyroglutamyl peptides in Japanese rice wine (sake): presence of hepatoprotective pyroGlu-Leu.
Topics: Aspergillus oryzae; Dipeptides; Fermentation; Oryza; Peptide Hydrolases; Peptides; Pyrrolidonecarboxylic Acid; Saccharomyces cerevisiae; Wine | 2013 |
Anti-inflammatory effect of pyroglutamyl-leucine on lipopolysaccharide-stimulated RAW 264.7 macrophages.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Cell Line; Dipeptides; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Inflammation; Inflammation Mediators; Interleukin-6; Lipopolysaccharides; Macrophages; MAP Kinase Signaling System; Mice; NF-kappa B; Nitric Oxide; Phosphorylation; Pyrrolidonecarboxylic Acid; Tumor Necrosis Factor-alpha | 2014 |
pyroGlu-Leu inhibits the induction of inducible nitric oxide synthase in interleukin-1β-stimulated primary cultured rat hepatocytes.
Topics: Animals; Cells, Cultured; Dipeptides; Hepatocytes; Interleukin-1beta; Male; NF-kappa B; Nitric Oxide Synthase Type II; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; RNA, Messenger; Transcriptional Activation | 2015 |
Antidepressant-like effect of food-derived pyroglutamyl peptides in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cell Proliferation; Depression; Dipeptides; Hindlimb Suspension; Hippocampus; Male; Mice; Neurogenesis; Neurons; Pyrrolidonecarboxylic Acid; Swimming | 2015 |