pyroglutamyl-glutamyl-proline amide and pyrrolidonecarboxylic acid

pyroglutamyl-glutamyl-proline amide has been researched along with pyrrolidonecarboxylic acid in 59 studies

Compound Research Comparison

Studies (pyroglutamyl-glutamyl-proline amide)	Trials (pyroglutamyl-glutamyl-proline amide)	Recent Studies (post-2010) (pyroglutamyl-glutamyl-proline amide)	Studies (pyrrolidonecarboxylic acid)	Trials (pyrrolidonecarboxylic acid)	Recent Studies (post-2010) (pyrrolidonecarboxylic acid)
62	0	0	3,005	101	671

Research

Studies (59)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (3.39)	18.7374
1990's	33 (55.93)	18.2507
2000's	24 (40.68)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Aitken, A; Garcia, JR; Khan, Z; Smyth, DG	1
Cockle, SM; Morrell, JM; Thetford, CR	1
Ashworth, RJ; Cockle, SM; Visser, TJ	1
Aitken, A; Ashworth, RJ; Cockle, SM; Morrell, JM; Patel, Y	1
Aitken, A; Beg, F; Cockle, SM; Smyth, DG	1
Aitken, A; Beg, F; Cockle, SM; Morrell, JM; Smyth, DG	1
Cockle, SM; Hamilton, C; Malone, PR; Mundy, AR; Prater, GV; Thetford, CR	1
Cockle, SM	1
Allaerts, W; de Jong, FH; Everts, ME; Hofland, LJ; Jeucken, PH; Klootwijk, W; Kramer, P; Linkels, E; Rondeel, JM; van Haasteren, GA	1
de Greef, WJ; Klootwijk, W; Linkels, E; Rondeel, JM; van Haasteren, GA; Visser, TJ	1
Akinsanya, KO; Bloom, SR; Ghatei, MA	1
Ashworth, RJ; Cockle, SM; Harvey, S; Trudeau, VL	1
Cockle, SM; Siviter, RJ	1
de Greef, WJ; Klootwijk, W; Linkels, E; Rondeel, JM; Visser, TJ	1
Ashworth, RJ; Cockle, SM; Ham, J	1
Cockle, SM; Fraser, LR; Green, CM; Watson, PF	2
Khan, Z; Smyth, DG	1
del Rio Garcia, J; Huber, A; Kreil, G; Linden, H; Smyth, D	1
de Greef, WJ; de Herder, WW; Klootwijk, W; Krenning, EP; Kwekkeboom, DJ; Lamberts, SW; Visser, TJ	1
Cockle, SM; Kennedy, AM; Morrell, JM; Siviter, RJ	1
Bauer, K; Cockle, SM; de Boer, RD; de Greef, WJ; de Herder, WW; Klootwijk, W; Sleddens-Linkels, E; Visser, TJ	1
Autar, R; Boevé, ER; de Boer, R; de Greef, WJ; de Herder, WW; Jansen, CA; Klootwijk, W; Sleddens-Linkels, E; Visser, TJ	1
Cockle, SM; Fraser, LR; Hanyaloglu, A	1
de Greef, WJ; de Herder, WW; de Jong, FH; Klootwijk, W; Lambalk, CB; Sleddens-Linkels, E; Visser, TJ	1
Fraser, LR	5
del Rio-Garcia, J; Fraser, H; Huber, AE; Kreil, G; Smyth, DG	1
Cremades, A; Del Rio-Garcia, J; Peñafiel, R; Rausell, V; Smyth, DG	1
Adeoya-Osiguwa, SA; Dudley, RK; Fraser, LR; Hosseini, R	1
del Rio-Garcia, J; Fraser, HM; Rausell, V; Smyth, DG; Tobaruela, M	1
Adeoya-Osiguwa, S; Fraser, LR	1
Asano, A; Fraser, LR; Fujiwara, T; Funahashi, H; Nagai, T; Niwa, K	1
Koch, ML; Koskinen, LO; Svedberg, J	1
Alvarez, AL; Finkielman, S; García, SI; Martinez, VN; Pirola, CJ; Porto, PI	1
Fujiwara, T; Funahashi, H; Nagai, T	1
Adeoya-Osiguwa, SA; Fraser, LR	2
Meyerhoff, JL; Pekary, AE; Sattin, A	1
Fraser, LR; Pondel, MD; Vinson, GP	1
Huang, M; Huang, X; Lebo, R; Ma, Y; Milunsky, A; Pan, A; Sun, Y; Xia, Q; Xiao, C; Zhang, G; Zhang, S	1
Koenig, ML; Long, JB; Meyerhoff, JL; Sgarlat, CM; Yourick, DL	1
Hinkle, PM; Pekary, AE; Sattin, A; Senanayaki, S	1
Cheong, HT; Hwang, IS; Kim, CI; Park, CK; Yang, BK	1
Eugene Pekary, A; Sattin, A; Senanayake, S	1
Braddy, AC; Nguyen, V; Prokai, L; Prokai-Tatrai, K; Stevens, SM; Zharikova, AD	1
Ma, Y; Zhang, S	1
Adeoya-Osiguwa, SA; Baxendale, RW; Fraser, LR	1
del Rio-Garcia, J; Ruiz-Alcaraz, AJ	1
Demuth, HU; Hoffmann, T; Ludwig, HH; Manhart, S; Schilling, S; Wasternack, C	1
Fraser, LR; Osiguwa, OO	1
Adeoya-Osiguwa, S; Baxendale, RW; Fraser, LR; Mededovic, S; Osiguwa, OO	1
Baldi, E; Brewis, IA; Ford, WC; Fraser, LR; Gadella, BM; Harrison, RA; Holt, WV; Luconi, M; Moore, HD	1
Nguyen, V; Prokai, L; Prokai-Tatrai, K; Teixido, M; Zharikova, AD	1
Pekary, AE; Sattin, A; Stevens, SA	1
Nguyen, V; Prokai, L; Zharikova, AD	1

Reviews

10 review(s) available for pyroglutamyl-glutamyl-proline amide and pyrrolidonecarboxylic acid

Article	Year
Sperm capacitation and the acrosome reaction. Human reproduction (Oxford, England), 1998, Volume: 13 Suppl 1 Topics: Acrosome; Animals; Female; Humans; Ions; Male; Pyrrolidonecarboxylic Acid; Sperm Capacitation; Sperm-Ovum Interactions; Thyrotropin-Releasing Hormone	1998
Fertilization promoting peptide: an important regulator of sperm function in vivo? Reviews of reproduction, 1998, Volume: 3, Issue:3 Topics: Animals; Humans; Male; Nuclear Proteins; Pyrrolidonecarboxylic Acid; Spermatozoa; Structure-Activity Relationship; Thyrotropin-Releasing Hormone	1998
Role of fertilization promoting peptide (FPP) in modulating mammalian sperm function. Frontiers in bioscience : a journal and virtual library, 1998, Dec-01, Volume: 3 Topics: Animals; Humans; Male; Mammals; Mice; Pyrrolidonecarboxylic Acid; Receptors, Cell Surface; Signal Transduction; Spermatozoa; Swine; Thyrotropin-Releasing Hormone	1998
The modulation of sperm function by fertilization promoting peptide. Human reproduction (Oxford, England), 1998, Volume: 13 Suppl 4 Topics: Animals; Humans; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Mice; Microtubule-Associated Proteins; Nuclear Proteins; Pyrrolidonecarboxylic Acid; Sperm Capacitation; Spermatozoa; t-Complex Genome Region; Thyrotropin-Releasing Hormone; Ubiquitin-Protein Ligases	1998
New insights into possible causes of male infertility. Human reproduction (Oxford, England), 1999, Volume: 14 Suppl 1 Topics: Calcium-Transporting ATPases; Enzyme Activation; Humans; Infertility, Male; Male; Pyrrolidonecarboxylic Acid; Sperm Capacitation; Thyrotropin-Releasing Hormone	1999
Fertilization promoting peptide--a possible regulator of sperm function in vivo. Vitamins and hormones, 2001, Volume: 63 Topics: Animals; Humans; Male; Pyrrolidonecarboxylic Acid; Receptors, Cell Surface; Signal Transduction; Spermatozoa; Thyrotropin-Releasing Hormone	2001
[Advances in modulation of mammalian sperm function by fertilization promoting peptide]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, 2003, Volume: 20, Issue:2 Topics: Acrosome; Adenylyl Cyclases; Animals; Cyclic AMP; Humans; Male; Pyrrolidonecarboxylic Acid; Signal Transduction; Spermatozoa; Thyrotropin-Releasing Hormone	2003
First messenger regulation of capacitation via G protein-coupled mechanisms: a tale of serendipity and discovery. Molecular human reproduction, 2003, Volume: 9, Issue:12 Topics: Adenosine; Adenylyl Cyclases; Animals; Calcitonin; Cyclic AMP; GTP-Binding Protein alpha Subunits, Gs; Heterotrimeric GTP-Binding Proteins; Humans; Male; Mice; Pyrrolidonecarboxylic Acid; Receptors, G-Protein-Coupled; Receptors, Purinergic P1; Signal Transduction; Sperm Capacitation; Spermatozoa; Thyrotropin-Releasing Hormone	2003
First messenger regulation of mammalian sperm function via adenylyl cyclase/cAMP. The Journal of reproduction and development, 2005, Volume: 51, Issue:1 Topics: Adenylyl Cyclases; Angiotensin II; Animals; Calcitonin; Cyclic AMP; Female; Humans; Male; Mice; Models, Biological; Pyrrolidonecarboxylic Acid; Signal Transduction; Sperm Capacitation; Spermatozoa; Thyrotropin-Releasing Hormone	2005
Molecular mechanisms during sperm capacitation. Human fertility (Cambridge, England), 2005, Volume: 8, Issue:4 Topics: Acrosome Reaction; Adenosine; Animals; Calcitonin; Cell Membrane; Fallopian Tubes; Female; Fertilization; Humans; Male; Pyrrolidonecarboxylic Acid; Signal Transduction; Sperm Capacitation; Spermatozoa; Thyrotropin-Releasing Hormone	2005

Other Studies

49 other study(ies) available for pyroglutamyl-glutamyl-proline amide and pyrrolidonecarboxylic acid

Article	Year
Isolation and identification of two neutral thyrotropin releasing hormone-like peptides, pyroglutamylphenylalanineproline amide and pyroglutamylglutamineproline amide, from human seminal fluid. The Journal of biological chemistry, 1992, Apr-15, Volume: 267, Issue:11 Topics: Amino Acid Sequence; Chromatography, Gel; Chromatography, High Pressure Liquid; Humans; Male; Molecular Sequence Data; Oligopeptides; Pyrrolidonecarboxylic Acid; Radioimmunoassay; Semen; Spectrometry, Mass, Fast Atom Bombardment; Thyrotropin-Releasing Hormone	1992
TRH-related peptides in the rabbit prostate complex during development. Biochimica et biophysica acta, 1992, Jan-23, Volume: 1115, Issue:3 Topics: Aging; Amino Acid Sequence; Animals; Chromatography, Gel; Chromatography, Ion Exchange; Male; Molecular Sequence Data; Oligopeptides; Peptide Fragments; Prostate; Pyrrolidonecarboxylic Acid; Rabbits; Sexual Maturation; Thyrotropin-Releasing Hormone; Trypsin	1992
The TRH-like peptide pGlu-Glu-ProNH2 is present in the porcine pituitary but not in reproductive tissues. Biochemical and biophysical research communications, 1991, Dec-31, Volume: 181, Issue:3 Topics: Aging; Amino Acid Sequence; Animals; Chromatography, Gel; Chromatography, Ion Exchange; Female; Molecular Sequence Data; Oligopeptides; Organ Specificity; Ovarian Follicle; Ovary; Pituitary Gland; Pyrrolidonecarboxylic Acid; Radioimmunoassay; Swine; Thyrotropin-Releasing Hormone	1991
Pyroglutamylglutamylprolineamide is present in rat anterior and posterior pituitary gland. The Journal of endocrinology, 1991, Volume: 129, Issue:1 Topics: Animals; Chromatography, Gel; Female; Hypothalamus; Oligopeptides; Pituitary Gland, Anterior; Pituitary Gland, Posterior; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thyrotropin-Releasing Hormone	1991
A novel peptide, pyroglutamylglutamylproline amide, in the rabbit prostate complex, structurally related to thyrotrophin-releasing hormone. The Journal of biological chemistry, 1989, May-15, Volume: 264, Issue:14 Topics: Amino Acid Sequence; Amino Acids; Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Immunoassay; Male; Mass Spectrometry; Molecular Sequence Data; Molecular Weight; Oligopeptides; Prostate; Protein Precursors; Pyrrolidonecarboxylic Acid; Rabbits; Thyrotropin-Releasing Hormone	1989
The TRH-related peptide pyroglutamyglutamylprolinamide is present in human semen. FEBS letters, 1989, Jul-31, Volume: 252, Issue:1-2 Topics: Adult; Amino Acids; Animals; Cattle; Chromatography, High Pressure Liquid; Humans; Male; Mass Spectrometry; Oligopeptides; Pyrrolidonecarboxylic Acid; Semen; Sheep; Thyrotropin-Releasing Hormone	1989
Peptides related to thyrotrophin-releasing hormone (TRH) in human prostate and semen. Biochimica et biophysica acta, 1994, Oct-21, Volume: 1227, Issue:1-2 Topics: Adult; Aged; Amino Acid Sequence; Animals; Biomarkers; Half-Life; Humans; Male; Molecular Sequence Data; Peptides; Prostate; Prostatic Hyperplasia; Pyrrolidonecarboxylic Acid; Rabbits; Radioimmunoassay; Semen; Thyrotropin-Releasing Hormone	1994
Fertilization-promoting peptide: a novel peptide, structurally similar to TRH, with potent physiological activity. The Journal of endocrinology, 1995, Volume: 146, Issue:1 Topics: Adult; Aged; Animals; Biomarkers; Female; Humans; Male; Middle Aged; Pituitary Gland, Anterior; Prostate; Prostatic Diseases; Pyrrolidonecarboxylic Acid; Rabbits; Rats; Thyrotropin-Releasing Hormone	1995
Further studies on the regulation, localization and function of the TRH-like peptide pyroglutamyl-glutamyl-prolineamide in the rat anterior pituitary gland. The Journal of endocrinology, 1995, Volume: 146, Issue:2 Topics: Animals; Animals, Newborn; Cells, Cultured; Estrus; Female; Gonadotropin-Releasing Hormone; Male; Pituitary Gland, Anterior; Pyrrolidonecarboxylic Acid; Radioimmunoassay; Rats; Rats, Wistar; Thyrotropin-Releasing Hormone	1995
Regulation of the TRH-like peptide pyroglutamyl-glutamyl-prolineamide in the rat anterior pituitary gland. The Journal of endocrinology, 1995, Volume: 145, Issue:1 Topics: Adrenalectomy; Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Disulfiram; Female; Male; Orchiectomy; Ovariectomy; Pituitary Gland, Anterior; Pituitary Gland, Posterior; Pyrrolidonecarboxylic Acid; Radioimmunoassay; Rats; Rats, Wistar; Testosterone; Thyroidectomy; Thyrotropin-Releasing Hormone	1995
Gonadal steroids regulate rat anterior pituitary levels of TSH-releasing hormone- and pyroglutamyl-glutamyl-proline amide-like immunoreactivity. Endocrinology, 1995, Volume: 136, Issue:2 Topics: Animals; Antibodies; Estradiol; Estrogens; Female; Hypothalamus; Immunoassay; Male; Orchiectomy; Ovariectomy; Pituitary Gland, Anterior; Pyrrolidonecarboxylic Acid; Rabbits; Rats; Rats, Wistar; Sex Factors; Testosterone; Thyrotropin-Releasing Hormone	1995
pGlutamylglutamylprolineamide modulation of growth hormone secretion in domestic fowl: antagonism of thyrotrophin-releasing hormone action? The Journal of endocrinology, 1993, Volume: 138, Issue:1 Topics: Animals; Chickens; Down-Regulation; Female; Growth Hormone; In Vitro Techniques; Male; Pituitary Gland; Pyrrolidonecarboxylic Acid; Receptors, Thyrotropin-Releasing Hormone; Thyrotropin-Releasing Hormone	1993
Peptides related to thyrotrophin-releasing hormone are degraded in seminal plasma by an enzyme similar to prolyl endopeptidase. The Journal of endocrinology, 1995, Volume: 144, Issue:1 Topics: Animals; Bacitracin; Chromatography, High Pressure Liquid; Edetic Acid; Male; Prolyl Oligopeptidases; Protease Inhibitors; Pyrrolidonecarboxylic Acid; Rabbits; Semen; Serine Endopeptidases; Thyrotropin-Releasing Hormone; Zinc	1995
Neural differentiation of the human neuroblastoma cell line IMR32 induces production of a thyrotropin-releasing hormone-like peptide. Brain research, 1994, Dec-05, Volume: 665, Issue:2 Topics: Blotting, Northern; Cell Differentiation; Chromatography, High Pressure Liquid; Humans; Neuroblastoma; Neurons; Pyrrolidonecarboxylic Acid; Radioimmunoassay; Thyrotropin-Releasing Hormone; Time Factors; Tumor Cells, Cultured	1994
The effects of pyroglutamylglutamylprolineamide, a peptide related to thyrotrophin-releasing hormone, on rat anterior pituitary cells in culture. The Journal of endocrinology, 1994, Volume: 142, Issue:1 Topics: Animals; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Female; Inositol Phosphates; Pituitary Gland, Anterior; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Thyrotropin-Releasing Hormone; Tumor Cells, Cultured	1994
Stimulating effect of pyroglutamylglutamylprolineamide, a prostatic, TRH-related tripeptide, on mouse sperm capacitation and fertilizing ability in vitro. Molecular reproduction and development, 1994, Volume: 38, Issue:2 Topics: Acrosome; Amino Acid Sequence; Animals; Chlortetracycline; Exocytosis; Female; Fertilization; Fertilization in Vitro; In Vitro Techniques; Male; Mice; Molecular Sequence Data; Prostate; Pyrrolidonecarboxylic Acid; Sperm Capacitation; Thyrotropin-Releasing Hormone	1994
Isolation and identification of N-terminally extended forms of 5-oxoprolylglutamylprolinamide (Glp-Glu-Pro-NH2), a thyrotropin-releasing-hormone (TRH)-like peptide present in human semen. European journal of biochemistry, 1993, Feb-15, Volume: 212, Issue:1 Topics: Amino Acid Sequence; Humans; Male; Molecular Sequence Data; Oligopeptides; Pyrrolidonecarboxylic Acid; Semen; Thyrotropin-Releasing Hormone	1993
The TRH-like peptides in rabbit testis are different from the TRH-like peptide in the prostate. FEBS letters, 1996, Jan-22, Volume: 379, Issue:1 Topics: Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Humans; Male; Molecular Sequence Data; Oligopeptides; Prostate; Protein Precursors; Pyrrolidonecarboxylic Acid; Rabbits; Semen; Testis; Thyrotropin-Releasing Hormone; Tissue Distribution	1996
High serum levels of the thyrotropin-releasing hormone-like peptide pyroglutamyl-glutamyl-prolineamide in patients with carcinoid tumors. The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:8 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carcinoid Tumor; Child; Chromatography, High Pressure Liquid; Female; Humans; Immune Sera; Male; Middle Aged; Pyrrolidonecarboxylic Acid; Radioimmunoassay; Reference Values; Thyrotropin-Releasing Hormone	1996
A possible mechanism of action for fertilization promoting peptide, a TRH-related tripeptide that promotes capacitation and fertilizing ability in mammalian spermatozoa. Molecular reproduction and development, 1996, Volume: 45, Issue:2 Topics: Animals; Cells, Cultured; Female; Fertilization; Humans; Male; Mice; Pyrrolidonecarboxylic Acid; Sperm Capacitation; Spermatozoa; Thyrotropin-Releasing Hormone	1996
Fertilization-promoting peptide in reproductive tissues and semen of the male marmoset (Callithrix jacchus). Molecular reproduction and development, 1997, Volume: 47, Issue:1 Topics: Animals; Bulbourethral Glands; Callithrix; Castration; Chromatography, Ion Exchange; Male; Prolyl Oligopeptidases; Prostate; Pyrrolidonecarboxylic Acid; Radioimmunoassay; Semen; Serine Endopeptidases; Testis; Testosterone; Thyrotropin-Releasing Hormone	1997
Urinary excretion of the TRH-like peptide pyroglutamyl-glutamyl-prolineamide in rats. The Journal of endocrinology, 1997, Volume: 153, Issue:3 Topics: Adrenal Glands; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Female; Half-Life; Hypothalamus; Male; Metabolic Clearance Rate; Ovary; Pancreas; Pituitary Gland; Prostate; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Salivary Glands; Thyroid Gland; Thyrotropin-Releasing Hormone	1997
Renal clearance of the thyrotropin-releasing hormone-like peptide pyroglutamyl-glutamyl-prolineamide in humans. The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:9 Topics: Adult; Aged; Anuria; Carcinoid Tumor; Chromatography, High Pressure Liquid; Constriction, Pathologic; Creatinine; Female; Humans; Kidney; Male; Middle Aged; Postoperative Period; Prostate-Specific Antigen; Prostatectomy; Pyrrolidonecarboxylic Acid; Reference Values; Thyrotropin-Releasing Hormone; Urologic Diseases	1997
A fertilization promoting peptide (FPP)-related tripeptide competitively inhibits responses to FPP: a cause of male subfertility? Molecular reproduction and development, 1997, Volume: 48, Issue:4 Topics: Adenosine; Animals; Binding, Competitive; Fertilization; Fertilization in Vitro; Humans; In Vitro Techniques; Infertility, Male; Male; Mice; Oligopeptides; Pyrrolidonecarboxylic Acid; Sperm Capacitation; Structure-Activity Relationship; Thyrotropin-Releasing Hormone	1997
Evidence that the TRH-like peptide pyroglutamyl-glutamyl-prolineamide in human serum may not be secreted by the pituitary gland. The Journal of endocrinology, 1997, Volume: 155, Issue:2 Topics: Adult; Aged; Chromatography, High Pressure Liquid; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Immunoradiometric Assay; Luteinizing Hormone; Male; Menstruation; Middle Aged; Obesity; Petrosal Sinus Sampling; Pituitary Gland; Pituitary Neoplasms; Postmenopause; Pyrrolidonecarboxylic Acid; Radioimmunoassay; Thyrotropin-Releasing Hormone	1997
Molecular cloning in the marmoset shows that semenogelin is not the precursor of the TRH-like peptide pGlu-Glu-Pro amide. Biochimica et biophysica acta, 1998, Sep-08, Volume: 1387, Issue:1-2 Topics: Amino Acid Sequence; Animals; Base Sequence; Callithrix; Cloning, Molecular; Gonadal Steroid Hormones; Humans; Male; Mammals; Molecular Sequence Data; Oligopeptides; Prostate; Protein Precursors; Pyrrolidonecarboxylic Acid; RNA, Messenger; Semen; Seminal Vesicle Secretory Proteins; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Thyrotropin-Releasing Hormone; Trypsin	1998
The thyrotropin-releasing hormone-like peptides pGlu-Phe-Pro amide and pGlu-Glu-Pro amide increase plasma triiodothyronine levels in the mouse; the activity is sensitive to testosterone. European journal of pharmacology, 1998, Sep-25, Volume: 358, Issue:1 Topics: Animals; Antineoplastic Agents, Hormonal; Castration; Female; Male; Mice; Oligopeptides; Pyrrolidonecarboxylic Acid; Testosterone; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine	1998
FPP modulates mammalian sperm function via TCP-11 and the adenylyl cyclase/cAMP pathway. Molecular reproduction and development, 1998, Volume: 51, Issue:4 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Chaperonins; Cyclic AMP; DNA-Binding Proteins; Immunoglobulin Fab Fragments; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Mice; Microtubule-Associated Proteins; Nuclear Proteins; Pyrrolidonecarboxylic Acid; Spermatozoa; t-Complex Genome Region; Testicular Hormones; Thyrotropin-Releasing Hormone; Ubiquitin-Protein Ligases	1998
Identification of the TRH-like peptides pGlu-Glu-Pro amide and pGlu-Phe-Pro amide in rat thyroid: regulation by thyroid status. Regulatory peptides, 1999, May-31, Volume: 81, Issue:1-3 Topics: Animals; Chromatography, High Pressure Liquid; Hyperthyroidism; Hypothyroidism; Male; Oligopeptides; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Reference Values; Thyroid Gland; Thyrotropin-Releasing Hormone	1999
Modulation of adenylyl cyclase by FPP and adenosine involves stimulatory and inhibitory adenosine receptors and g proteins. Molecular reproduction and development, 1999, Volume: 53, Issue:4 Topics: Adenosine; Adenylyl Cyclases; Animals; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Guanosine Triphosphate; Intracellular Signaling Peptides and Proteins; Male; Mice; Microtubule-Associated Proteins; Nuclear Proteins; Pyrrolidonecarboxylic Acid; Receptors, Purinergic P1; Signal Transduction; Sperm Capacitation; Spermatozoa; t-Complex Genome Region; Thyrotropin-Releasing Hormone; Ubiquitin-Protein Ligases	1999
Both fertilization promoting peptide and adenosine stimulate capacitation but inhibit spontaneous acrosome loss in ejaculated boar spermatozoa in vitro. Molecular reproduction and development, 2000, Volume: 55, Issue:1 Topics: Acrosome; Adenosine; Animals; Caffeine; Cells, Cultured; Chlortetracycline; Dose-Response Relationship, Drug; Humans; Male; Mice; Pyrrolidonecarboxylic Acid; Sperm Capacitation; Spermatozoa; Swine; Thyrotropin-Releasing Hormone	2000
Cerebrovascular effects of the TRH analogues pGlu-3-methyl-His-Pro amide and pGlu-Glu-Pro amide: a comparison with TRH. Upsala journal of medical sciences, 2000, Volume: 105, Issue:1 Topics: Animals; Blood Gas Analysis; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Hemodynamics; Laser-Doppler Flowmetry; Male; Molecular Structure; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Thyrotropin-Releasing Hormone; Vasodilator Agents	2000
Expression of TRH and TRH-like peptides in a human glioblastoma-astrocytoma cell line (U-373-MG). The Journal of endocrinology, 2000, Volume: 166, Issue:3 Topics: Analysis of Variance; Astrocytoma; Brain Neoplasms; Central Nervous System; Chromatography, DEAE-Cellulose; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Glioblastoma; Humans; Models, Biological; Pyrrolidonecarboxylic Acid; Radioimmunoassay; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thyrotropin-Releasing Hormone; Tumor Cells, Cultured	2000
Modulation of the function of boar spermatozoa via adenosine and fertilization promoting peptide receptors reduce the incidence of polyspermic penetration into porcine oocytes. Biology of reproduction, 2000, Volume: 63, Issue:4 Topics: Adenosine; Animals; Bucladesine; Cryopreservation; Female; Male; Purinergic P1 Receptor Antagonists; Pyrrolidonecarboxylic Acid; Receptors, Cytoplasmic and Nuclear; Receptors, Purinergic P1; Semen Preservation; Sperm-Ovum Interactions; Spermatozoa; Swine; Theobromine; Thyrotropin-Releasing Hormone	2000
Fertilization promoting peptide and adenosine, acting as first messengers, regulate cAMP production and consequent protein tyrosine phosphorylation in a capacitation-dependent manner. Molecular reproduction and development, 2000, Volume: 57, Issue:4 Topics: Adenosine; Animals; Cholera Toxin; Cyclic AMP; Male; Mice; Pertussis Toxin; Phosphorylation; Purinergic P1 Receptor Agonists; Pyrrolidonecarboxylic Acid; Signal Transduction; Sperm Capacitation; Thyrotropin-Releasing Hormone; Time Factors; Tyrosine; Virulence Factors, Bordetella	2000
Electroconvulsive seizures modulate levels of thyrotropin releasing hormone and related peptides in rat hypothalamus, cingulate and lateral cerebellum. Brain research, 2000, Nov-24, Volume: 884, Issue:1--2 Topics: Animals; Cerebellum; Electroconvulsive Therapy; Electroshock; Gyrus Cinguli; Hypothalamus; Male; Muscle Proteins; Neurons; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Seizures; Stress, Physiological; Thyrotropin-Releasing Hormone	2000
Calcitonin, angiotensin II and FPP significantly modulate mouse sperm function. Molecular human reproduction, 2001, Volume: 7, Issue:3 Topics: Angiotensin II; Animals; Calcitonin; Male; Mice; Pyrrolidonecarboxylic Acid; Sperm Capacitation; Spermatozoa; Thyrotropin-Releasing Hormone	2001
Molecular characterization of the TCP11 gene which is the human homologue of the mouse gene encoding the receptor of fertilization promoting peptide. Molecular human reproduction, 2002, Volume: 8, Issue:1 Topics: Amino Acid Sequence; Animals; Base Sequence; Chromosome Mapping; Chromosomes, Human, Pair 6; DNA-Binding Proteins; Exons; Humans; In Situ Hybridization, Fluorescence; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Mice; Microtubule-Associated Proteins; Molecular Sequence Data; Nuclear Proteins; Nucleic Acid Hybridization; Pyrrolidonecarboxylic Acid; Receptors, Cell Surface; Sequence Alignment; t-Complex Genome Region; Testicular Hormones; Testis; Thyrotropin-Releasing Hormone; Ubiquitin-Protein Ligases	2002
In vitro neuroprotection against glutamate-induced toxicity by pGlu-Glu-Pro-NH(2) (EEP). Peptides, 2001, Volume: 22, Issue:12 Topics: Animals; Glutamates; Neuroprotective Agents; Pyrrolidonecarboxylic Acid; Rats; Thyrotropin-Releasing Hormone	2001
Role of TRH receptors as possible mediators of analeptic actions of TRH-like peptides. Brain research, 2002, May-10, Volume: 935, Issue:1-2 Topics: Amino Acid Sequence; Animals; Brain; Calcium; Calcium Signaling; Cells, Cultured; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Humans; Male; Neural Pathways; Neurons; Neuropeptides; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Receptors, Thyrotropin-Releasing Hormone; Thyrotropin-Releasing Hormone	2002
Effect of a fertilization-promoting peptide on the fertilizing ability and glycosidase activity in vitro of frozen-thawed spermatozoa in the pig. Animal reproduction science, 2002, Jul-15, Volume: 72, Issue:1-2 Topics: Acrosome; Animals; Cryopreservation; Dose-Response Relationship, Drug; Fertility Agents, Male; Fertilization in Vitro; Glycoside Hydrolases; Male; Pyrrolidonecarboxylic Acid; Sperm Capacitation; Sperm-Ovum Interactions; Spermatozoa; Swine; Thyrotropin-Releasing Hormone; Time Factors	2002
Cocaine regulates TRH-related peptides in rat brain. Neurochemistry international, 2002, Volume: 41, Issue:6 Topics: Animals; Brain; Chromatography, High Pressure Liquid; Cocaine; Male; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Thyrotropin-Releasing Hormone; Time Factors	2002
Prodrugs to enhance central nervous system effects of the TRH-like peptide pGlu-Glu-Pro-NH2. Bioorganic & medicinal chemistry letters, 2003, Mar-24, Volume: 13, Issue:6 Topics: Animals; Barbiturates; Blood-Brain Barrier; Central Nervous System; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Half-Life; In Vitro Techniques; Kinetics; Lipids; Membranes, Artificial; Mice; Prodrugs; Pyrrolidonecarboxylic Acid; Sleep; Thyrotropin-Releasing Hormone	2003
Characterization of a circulating N-extended form of the thyrotropin-releasing hormone-like peptide pGlu-Glu-Pro amide in human plasma. The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:12 Topics: Animals; Anions; Cations; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Humans; Male; Pyrrolidonecarboxylic Acid; Rabbits; Rats; Rats, Sprague-Dawley; Thyrotropin-Releasing Hormone; Trypsin	2003
Substrate specificity of glutaminyl cyclases from plants and animals. Biological chemistry, 2003, Volume: 384, Issue:12 Topics: Amino Acids; Aminoacyltransferases; Animals; Carica; Catalysis; Cattle; Cyclization; Dipeptides; Enzyme Stability; Gastrins; Glutamate Dehydrogenase; Glutamine; Gonadotropin-Releasing Hormone; Humans; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kinetics; NAD; Neurotensin; Oligopeptides; Osmolar Concentration; Pyrrolidonecarboxylic Acid; Recombinant Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity; Thyrotropin-Releasing Hormone	2003
Human sperm responses to calcitonin, angiotensin II and fertilization-promoting peptide in prepared semen samples from normal donors and infertility patients. Human reproduction (Oxford, England), 2004, Volume: 19, Issue:3 Topics: Angiotensin II; Animals; Calcitonin; Case-Control Studies; Cricetinae; Drug Combinations; Humans; Infertility, Male; Male; Pyrrolidonecarboxylic Acid; Semen; Sperm Capacitation; Sperm-Ovum Interactions; Spermatozoa; Thyrotropin-Releasing Hormone; Tissue Donors	2004
A pyridinium-substituted analog of the TRH-like tripeptide pGlu-Glu-Pro-NH2 and its prodrugs as central nervous system agents. Medicinal chemistry (Shariqah (United Arab Emirates)), 2005, Volume: 1, Issue:2 Topics: Animals; Central Nervous System; Central Nervous System Agents; Drug Design; In Vitro Techniques; Mice; Molecular Structure; Prodrugs; Pyridinium Compounds; Pyrrolidonecarboxylic Acid; Structure-Activity Relationship; Swimming; Thyrotropin-Releasing Hormone	2005
Circadian rhythms of TRH-like peptide levels in rat brain. Brain research, 2006, Dec-13, Volume: 1125, Issue:1 Topics: Analysis of Variance; Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Circadian Rhythm; Male; Peptide Fragments; Pyrrolidonecarboxylic Acid; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Thyrotropin-Releasing Hormone; Time Factors	2006
Evidence for interplay between thyrotropin-releasing hormone (TRH) and its structural analogue pGlu-Glu-Pro-NH2 ([Glu2]TRH) in the brain: an in vivo microdialysis study. Neuroscience letters, 2007, Mar-19, Volume: 415, Issue:1 Topics: Acetylcholine; Animals; Brain Chemistry; Drug Synergism; Extracellular Fluid; Hippocampus; Male; Microdialysis; Molecular Structure; Neurotransmitter Agents; Presynaptic Terminals; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Thyrotropin-Releasing Hormone; Up-Regulation	2007