Page last updated: 2024-09-03

pyroglutamyl-glutamyl-proline amide and adenosine

pyroglutamyl-glutamyl-proline amide has been researched along with adenosine in 8 studies

Compound Research Comparison

Studies
(pyroglutamyl-glutamyl-proline amide)
Trials
(pyroglutamyl-glutamyl-proline amide)
Recent Studies (post-2010)
(pyroglutamyl-glutamyl-proline amide)
Studies
(adenosine)
Trials
(adenosine)
Recent Studies (post-2010) (adenosine)
620032,5361,0758,930

Protein Interaction Comparison

ProteinTaxonomypyroglutamyl-glutamyl-proline amide (IC50)adenosine (IC50)
high affinity choline transporter 1 isoform aHomo sapiens (human)0.3851
Sodium/nucleoside cotransporter 1Homo sapiens (human)5.5
Sodium/nucleoside cotransporter 2Homo sapiens (human)5.5
Adenosine receptor A3Homo sapiens (human)0.0011
Adenosine receptor A1Homo sapiens (human)0.0023
Equilibrative nucleoside transporter 1Homo sapiens (human)63
Solute carrier family 28 member 3Homo sapiens (human)3.3

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's5 (62.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cockle, SM; Fraser, LR; Hanyaloglu, A1
Adeoya-Osiguwa, SA; Dudley, RK; Fraser, LR; Hosseini, R1
Adeoya-Osiguwa, S; Fraser, LR1
Asano, A; Fraser, LR; Fujiwara, T; Funahashi, H; Nagai, T; Niwa, K1
Fujiwara, T; Funahashi, H; Nagai, T1
Adeoya-Osiguwa, SA; Fraser, LR1
Adeoya-Osiguwa, SA; Baxendale, RW; Fraser, LR1
Baldi, E; Brewis, IA; Ford, WC; Fraser, LR; Gadella, BM; Harrison, RA; Holt, WV; Luconi, M; Moore, HD1

Reviews

2 review(s) available for pyroglutamyl-glutamyl-proline amide and adenosine

ArticleYear
First messenger regulation of capacitation via G protein-coupled mechanisms: a tale of serendipity and discovery.
    Molecular human reproduction, 2003, Volume: 9, Issue:12

    Topics: Adenosine; Adenylyl Cyclases; Animals; Calcitonin; Cyclic AMP; GTP-Binding Protein alpha Subunits, Gs; Heterotrimeric GTP-Binding Proteins; Humans; Male; Mice; Pyrrolidonecarboxylic Acid; Receptors, G-Protein-Coupled; Receptors, Purinergic P1; Signal Transduction; Sperm Capacitation; Spermatozoa; Thyrotropin-Releasing Hormone

2003
Molecular mechanisms during sperm capacitation.
    Human fertility (Cambridge, England), 2005, Volume: 8, Issue:4

    Topics: Acrosome Reaction; Adenosine; Animals; Calcitonin; Cell Membrane; Fallopian Tubes; Female; Fertilization; Humans; Male; Pyrrolidonecarboxylic Acid; Signal Transduction; Sperm Capacitation; Spermatozoa; Thyrotropin-Releasing Hormone

2005

Other Studies

6 other study(ies) available for pyroglutamyl-glutamyl-proline amide and adenosine

ArticleYear
A fertilization promoting peptide (FPP)-related tripeptide competitively inhibits responses to FPP: a cause of male subfertility?
    Molecular reproduction and development, 1997, Volume: 48, Issue:4

    Topics: Adenosine; Animals; Binding, Competitive; Fertilization; Fertilization in Vitro; Humans; In Vitro Techniques; Infertility, Male; Male; Mice; Oligopeptides; Pyrrolidonecarboxylic Acid; Sperm Capacitation; Structure-Activity Relationship; Thyrotropin-Releasing Hormone

1997
FPP modulates mammalian sperm function via TCP-11 and the adenylyl cyclase/cAMP pathway.
    Molecular reproduction and development, 1998, Volume: 51, Issue:4

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Chaperonins; Cyclic AMP; DNA-Binding Proteins; Immunoglobulin Fab Fragments; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Mice; Microtubule-Associated Proteins; Nuclear Proteins; Pyrrolidonecarboxylic Acid; Spermatozoa; t-Complex Genome Region; Testicular Hormones; Thyrotropin-Releasing Hormone; Ubiquitin-Protein Ligases

1998
Modulation of adenylyl cyclase by FPP and adenosine involves stimulatory and inhibitory adenosine receptors and g proteins.
    Molecular reproduction and development, 1999, Volume: 53, Issue:4

    Topics: Adenosine; Adenylyl Cyclases; Animals; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Guanosine Triphosphate; Intracellular Signaling Peptides and Proteins; Male; Mice; Microtubule-Associated Proteins; Nuclear Proteins; Pyrrolidonecarboxylic Acid; Receptors, Purinergic P1; Signal Transduction; Sperm Capacitation; Spermatozoa; t-Complex Genome Region; Thyrotropin-Releasing Hormone; Ubiquitin-Protein Ligases

1999
Both fertilization promoting peptide and adenosine stimulate capacitation but inhibit spontaneous acrosome loss in ejaculated boar spermatozoa in vitro.
    Molecular reproduction and development, 2000, Volume: 55, Issue:1

    Topics: Acrosome; Adenosine; Animals; Caffeine; Cells, Cultured; Chlortetracycline; Dose-Response Relationship, Drug; Humans; Male; Mice; Pyrrolidonecarboxylic Acid; Sperm Capacitation; Spermatozoa; Swine; Thyrotropin-Releasing Hormone

2000
Modulation of the function of boar spermatozoa via adenosine and fertilization promoting peptide receptors reduce the incidence of polyspermic penetration into porcine oocytes.
    Biology of reproduction, 2000, Volume: 63, Issue:4

    Topics: Adenosine; Animals; Bucladesine; Cryopreservation; Female; Male; Purinergic P1 Receptor Antagonists; Pyrrolidonecarboxylic Acid; Receptors, Cytoplasmic and Nuclear; Receptors, Purinergic P1; Semen Preservation; Sperm-Ovum Interactions; Spermatozoa; Swine; Theobromine; Thyrotropin-Releasing Hormone

2000
Fertilization promoting peptide and adenosine, acting as first messengers, regulate cAMP production and consequent protein tyrosine phosphorylation in a capacitation-dependent manner.
    Molecular reproduction and development, 2000, Volume: 57, Issue:4

    Topics: Adenosine; Animals; Cholera Toxin; Cyclic AMP; Male; Mice; Pertussis Toxin; Phosphorylation; Purinergic P1 Receptor Agonists; Pyrrolidonecarboxylic Acid; Signal Transduction; Sperm Capacitation; Thyrotropin-Releasing Hormone; Time Factors; Tyrosine; Virulence Factors, Bordetella

2000