Page last updated: 2024-08-21

pyrithiamine and thiamine

pyrithiamine has been researched along with thiamine in 95 studies

Research

Studies (95)

TimeframeStudies, this research(%)All Research%
pre-199064 (67.37)18.7374
1990's11 (11.58)18.2507
2000's13 (13.68)29.6817
2010's6 (6.32)24.3611
2020's1 (1.05)2.80

Authors

AuthorsStudies
Hagedorn, H; Tobüren-Bots, I1
Berl, S; Nicklas, WJ; Plaitakis, A1
Cooper, JR; Pincus, JH1
Waldenlind, L1
Iwashima, A; Nose, Y; Wakabayashi, Y1
Gubler, CJ; Murdock, DS2
Edmondson, JW; Li, TK; Lumeng, L; Schenker, S1
Oguchi, E; Okazaki, M; Sakamoto, K; Yasuhara, H1
Hobara, R; Oguchi, E; Okazaki, M; Sakamoto, K; Toyoshima, Y1
Itokawa, Y; Nishino, K; Sasa, M; Takemoto, I1
Dlugonski, J; Edenharter, E; Schweingruber, AM; Schweingruber, ME1
Knoth, RL; Langlais, PJ; Mair, RG; Otto, TA; Rabchenuk, SA1
Knoth, RL; Langlais, PJ; Mair, RG; Rabchenuk, SA1
Knoth, RL; Mair, RG1
Bettendorff, L; Schoffeniels, E; Wins, P1
Iwashima, A; Kawasaki, Y; Kimura, Y1
Butterworth, RF; Héroux, M1
Butterworth, RF1
Besnard, AM; Butterworth, RF; Giguère, JF2
Comly, M; Levin, SW; Mukherjee, AB; Roecklein, B1
Ali, BH1
Greenwood, J; Pratt, OE1
Yoshioka, K1
Hoyumpa, AM; Nichols, S; Sheehan, JJ; Strickland, R; Yarborough, G1
Cooper, JR; Matsuda, T1
Iwashima, A; Nishimura, H; Nosaka, K; Yoshioka, K1
Gibson, GE; Hirsch, JA1
Carpenter, S; Hakim, AM; Pappius, HM1
Aikawa, H; Furuse, T; Iwasaki, Y; Moroji, T; Satoyoshi, E; Sumi, T; Watanabe, IS1
Iwashima, A; Nishimura, H; Nishino, H1
Irle, E; Markowitsch, HJ1
Hajikano, M; Hobara, R; Kato, H; Oguchi, E; Okazaki, M; Sakamoto, K1
Aikawa, H; Iwasaki, Y; Narabayashi, H; Watanabe, I1
Hobara, R; Okazaki, M; Sakamoto, K; Yasuhara, H1
Pekkanen, L1
Dunant, Y; Eder, L; Loctin, F1
Langlais, PJ; Zhang, SX1
Edenharter, E; Fankhauser, H; Niederberger, C; Schweingruber, ME1
Banks, K; David, E; Mana, MJ; Mumby, DG; Pinel, JP1
Singleton, CK1
Kubodera, T; Nishimura, A; Yamashita, N1
Brown, SB; Fitzsimons, JD; Vandenbyllaardt, L1
Dudeja, PK; Gill, R; Kavilaveettil, RJ; Said, HM; Tyagi, S1
Edenharter, E; Schweingruber, ME1
Meng, JS; Okeda, R1
Hazell, AS; Pannunzio, P; Pow, DV; Rama Rao, KV; Rambaldi, A1
DE CARO, L; GRANA, E; RINDI, G1
BRESNICK, E; CERECEDO, LR; EICH, S1
MERRIFIELD, RB; WOOLLEY, D1
KOEDAM, JC; STEYN-PARVE, EP; VAN RHEENEN, DL1
PAROLI, E2
CAPPELLI, V; PERRI, V1
ANDRAL, AM; BLAIZOT, J1
CAPELLI, V; DE CARO, L; PERRI, V1
WOLFE, SJ1
KOEDAM, JC1
DE CARO, L; FERRARI, G; PERRI, V; RINDI, G1
FERRARI, V1
DE CARO, L; FERRARI, G; RINDI, G1
EL-HAWARY, MF1
FLURI, R1
CAPPELLI, V; CERIANI, T; GRANA, E1
WENDEL, OW1
AIRTH, RL; FOERSTER, GE1
CHATTERJEE, GC; DAS, SK1
Jones, JH1
PERRI, V; RINDI, G1
LITTMAN, ML; MIWATANI, T1
GIACALONE, E; VENTURA, U1
JOSS, A1
DICKINSON, AM; OTT, WH; VANIDERSTINE, A1
CERECEDO, LR; EICH, S1
MINELLI, R; PISATI, F1
MASTROPIETRO-CANCELLIERI, MF; PRINCIVALLE, M1
RINDI, G1
Gomi, K; Hanamoto, H; Kubodera, T; Nakai, S; Nishimura, A; Watanabe, M; Yamashita, N; Yoshiuchi, K1
Pitkin, SR; Savage, LM1
Bellazzi, R; Magni, P; Nauti, A; Patrini, C; Rindi, G1
Butterworth, RF; Chan, H; Hazell, AS1
SEALOCK, RR; WHITE, HS1
Breaker, RR; Cohen-Chalamish, S; Emilsson, GM; Nakamura, S; Sudarsan, N1
Adalsteinsson, E; Bell, RL; Pfefferbaum, A; Sullivan, EV1
Chorna, N; Chornyy, S; Parkhomenko, J1
Cerecedo, LR; Eusebi, AJ1
Akaji, K; Kawasaki, Y; Konno, H; Nosaka, K; Onozuka, M1
Fan, Z; Ke, ZJ; Li, W; Luo, J; Sun, A; Yang, G; Zhang, Q1
Hamada, S; Hamaguchi-Hamada, K; Hirashima, H; Imaeda, M; Kurumata-Shigeto, M; Okamoto, Y1
Budwal, B; Buffa, FM; Chu, KY; Durrant, L; Ebner, DV; Folkes, LK; Higgins, GS; Howarth, A; McKenna, WG; Muschel, RJ; Prevo, R; Tiwana, GS; Yu, S1
Ratkiewicz, A; Siemieniuk, M; Tylicki, A; Łotowski, Z1
Deak, T; Savage, LM; Toledo Nunes, P; Vedder, LC1
Endo, Y; Hayashi, M; Konno, H; Mimuro, H; Nosaka, K; Tadano, K; Uchiyama, R1
Blecharz-Klin, K; Joniec-Maciejak, I; Krzysztoforska, K; Krzysztoforski, J; Piechal, A; Pyrzanowska, J; Widy-Tyszkiewicz, E; Wojnar, E1

Reviews

2 review(s) available for pyrithiamine and thiamine

ArticleYear
Cerebral thiamine-dependent enzyme changes in experimental Wernicke's encephalopathy.
    Metabolic brain disease, 1986, Volume: 1, Issue:3

    Topics: Animals; Disease Models, Animal; Pyridinium Compounds; Pyrithiamine; Thiamine; Thiamine Deficiency; Wernicke Encephalopathy

1986
Thiamine and selected thiamine antivitamins - biological activity and methods of synthesis.
    Bioscience reports, 2018, 02-28, Volume: 38, Issue:1

    Topics: Amprolium; Antimetabolites; Biological Transport; Drug Design; Humans; Oxythiamine; Pyrithiamine; Thiamine; Thiamine Pyrophosphate

2018

Other Studies

93 other study(ies) available for pyrithiamine and thiamine

ArticleYear
[Studies on the thiamine transport system in Bacillus cereus (author's transl)].
    Archives of microbiology, 1977, May-13, Volume: 113, Issue:1-2

    Topics: Adenine Nucleotides; Adenosine; Azides; Bacillus cereus; Biological Transport, Active; Calcium; Cyanides; Edetic Acid; Hydrogen-Ion Concentration; Kinetics; Magnesium; Phenyl Ethers; Potassium; Pyrithiamine; Sodium; Temperature; Thiamine; Uncoupling Agents

1977
Thiamine deficiency: selective impairment of the cerebellar serotonergic system.
    Neurology, 1978, Volume: 28, Issue:7

    Topics: Animals; Cerebellum; Desipramine; Hypothalamus; In Vitro Techniques; Male; Neurotransmitter Agents; Phenyl Ethers; Propylamines; Pyrithiamine; Rats; Serotonin; Synaptic Transmission; Synaptosomes; Thiamine; Thiamine Deficiency

1978
The role of thiamine in nervous tissue.
    Neurochemical research, 1979, Volume: 4, Issue:2

    Topics: Animals; Brain; Brain Diseases; Cattle; Coenzymes; Fishes; Ketoglutarate Dehydrogenase Complex; Nervous System Physiological Phenomena; Neural Conduction; Neurotransmitter Agents; Oxythiamine; Phosphorylation; Pyrithiamine; Pyruvate Dehydrogenase Complex; Rabbits; Rats; Synaptic Transmission; Syndrome; Thiamin Pyrophosphokinase; Thiamine; Thiamine Deficiency; Thiamine Pyrophosphate; Transketolase

1979
Possible role of thiamine in neuromuscular transmission.
    Acta physiologica Scandinavica, 1979, Volume: 105, Issue:1

    Topics: Action Potentials; Animals; Electric Stimulation; Masticatory Muscles; Muscle Contraction; Neuromuscular Junction; Oxythiamine; Pyrithiamine; Pyruvates; Rats; Synaptic Transmission; Thiamine; Thiamine Pyrophosphate; Transferases; Tubocurarine

1979
Inhibition of thiamine transport in Saccharomyces cerevisiae by thiamine disulfides.
    Journal of bacteriology, 1977, Volume: 131, Issue:3

    Topics: Cell Membrane; Disulfides; Pyrithiamine; Saccharomyces cerevisiae; Thiamine

1977
Differential determination of thiamine and its phosphates and hydroxyethiamine and pyrithiamine.
    Methods in enzymology, 1979, Volume: 62

    Topics: Animals; Indicators and Reagents; Oxythiamine; Pyridinium Compounds; Pyrithiamine; Spectrometry, Fluorescence; Thiamine; Thiamine Monophosphate; Thiamine Pyrophosphate; Thiamine Triphosphate; Thiazoles

1979
Transport and metabolism of thiamin in isolated rat hepatocytes.
    The Journal of biological chemistry, 1979, Aug-10, Volume: 254, Issue:15

    Topics: Animals; Biological Transport; Choline; In Vitro Techniques; Kinetics; Liver; Male; Pyrithiamine; Rats; Sodium; Thiamine; Thiamine Pyrophosphate; Uncoupling Agents

1979
[Effects of oxythiamine and pyrithiamine on rat liver. --Biochemical and morphological changes in the thiamine deficient rat (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1979, Volume: 75, Issue:4

    Topics: Animals; Body Weight; Diet; Lipid Metabolism; Liver; Male; Microscopy, Electron; Organ Size; Oxythiamine; Pyridinium Compounds; Pyrithiamine; Rats; Thiamine; Thiamine Deficiency; Thiazoles

1979
[Effect of oxythiamine and pyrithiamine on rat brain--morphological changes in the thiamine deficient rat brain (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1978, Volume: 74, Issue:8

    Topics: Animals; Brain; Brain Chemistry; Male; Oxythiamine; Pyridinium Compounds; Pyrithiamine; Rats; Thiamine; Thiamine Deficiency; Thiazoles

1978
The role of thiamine on excitable membrane of crayfish giant axon.
    Journal of nutritional science and vitaminology, 1976, Volume: 22 SUPPL

    Topics: Action Potentials; Animals; Astacoidea; Axons; Membrane Potentials; Pyrithiamine; Thiamine

1976
Thiamine in Schizosaccharomyces pombe: dephosphorylation, intracellular pool, biosynthesis and transport.
    Current genetics, 1991, Volume: 19, Issue:4

    Topics: Acid Phosphatase; Biological Transport; Drug Resistance, Microbial; Fungal Proteins; Gene Expression Regulation, Fungal; Genes, Fungal; Phosphorylation; Pyrithiamine; Schizosaccharomyces; Thiamine

1991
Analysis of aversively conditioned learning and memory in rats recovered from pyrithiamine-induced thiamine deficiency.
    Behavioral neuroscience, 1991, Volume: 105, Issue:3

    Topics: Alcohol Amnestic Disorder; Analysis of Variance; Animals; Avoidance Learning; Discrimination Learning; Disease Models, Animal; Electroshock; Escape Reaction; Gliosis; Male; Mammillary Bodies; Memory; Models, Neurological; Pyrithiamine; Rats; Thalamus; Thiamine; Thiamine Deficiency; Visual Perception

1991
Impairment of olfactory, auditory, and spatial serial reversal learning in rats recovered from pyrithiamine-induced thiamine deficiency.
    Behavioral neuroscience, 1991, Volume: 105, Issue:3

    Topics: Animals; Auditory Perception; Cues; Discrimination Learning; Male; Mammillary Bodies; Memory; Pyrithiamine; Rats; Reversal Learning; Serial Learning; Smell; Space Perception; Thalamus; Thiamine; Thiamine Deficiency

1991
Response latency and accuracy on a pretrained nonmatching-to-sample task in rats recovered from pyrithiamine-induced thiamine deficiency.
    Behavioral neuroscience, 1991, Volume: 105, Issue:3

    Topics: Animals; Conditioning, Operant; Cues; Discrimination Learning; Male; Mammillary Bodies; Memory; Models, Neurological; Pyrithiamine; Rats; Reaction Time; Thalamus; Thiamine; Thiamine Deficiency

1991
Regulation of ion uptake in membrane vesicles from rat brain by thiamine compounds.
    Biochemical and biophysical research communications, 1990, Sep-28, Volume: 171, Issue:3

    Topics: Animals; Biological Transport, Active; Brain; Cell Membrane; Chlorides; Female; gamma-Aminobutyric Acid; Kinetics; Oxythiamine; Pyrithiamine; Rats; Rats, Inbred Strains; Rubidium; Sodium; Thiamine; Thiamine Monophosphate; Thiamine Pyrophosphate; Thiamine Triphosphate

1990
Transport of 2-methyl-4-amino-5-hydroxymethylpyrimidine in Saccharomyces cerevisiae.
    Biochimica et biophysica acta, 1990, Feb-28, Volume: 1022, Issue:2

    Topics: Biological Transport, Active; Hydrogen-Ion Concentration; Kinetics; Mutation; Pyrimidines; Pyrithiamine; Saccharomyces cerevisiae; Temperature; Thiamine

1990
Effect of pyrithiamine treatment and subsequent thiamine rehabilitation on regional cerebral amino acids and thiamine-dependent enzymes.
    Journal of neurochemistry, 1989, Volume: 52, Issue:4

    Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Brain Diseases; Glutamates; Glutamic Acid; Ketoglutarate Dehydrogenase Complex; Ketone Oxidoreductases; Male; Pyridinium Compounds; Pyrithiamine; Pyruvate Dehydrogenase Complex; Rats; Rats, Inbred Strains; Thiamine; Thiamine Deficiency

1989
Activities of thiamine-dependent enzymes in two experimental models of thiamine-deficiency encephalopathy. 2. alpha-Ketoglutarate dehydrogenase.
    Neurochemical research, 1986, Volume: 11, Issue:4

    Topics: Animals; Brain; Diet; Disease Models, Animal; Ketoglutarate Dehydrogenase Complex; Ketone Oxidoreductases; Male; Pyrithiamine; Rats; Rats, Inbred Strains; Thiamine; Time Factors; Wernicke Encephalopathy

1986
Intrauterine growth retardation induced by thiamine deficiency and pyrithiamine during pregnancy in the rat.
    American journal of obstetrics and gynecology, 1985, Feb-15, Volume: 151, Issue:4

    Topics: Animals; Body Weight; Brain; Female; Fetal Growth Retardation; Fetus; Liver; Organ Size; Placenta; Pregnancy; Pyridinium Compounds; Pyrithiamine; Rats; Rats, Inbred Strains; Thiamine; Thiamine Deficiency

1985
Activities of thiamine-dependent enzymes in two experimental models of thiamine-deficiency encephalopathy: 1. The pyruvate dehydrogenase complex.
    Neurochemical research, 1985, Volume: 10, Issue:10

    Topics: Animals; Brain Diseases, Metabolic; Brain Stem; Disease Models, Animal; Male; Pyrithiamine; Pyruvate Dehydrogenase Complex; Rats; Rats, Inbred Strains; Reflex; Thiamine; Thiamine Deficiency; Transketolase

1985
Effect of some monoamine oxidase inhibitors on the thiamin status of rabbits.
    British journal of pharmacology, 1985, Volume: 86, Issue:4

    Topics: Animals; Brain; Eating; Erythrocytes; Growth; Lactates; Liver; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxythiamine; Pyrithiamine; Pyruvates; Rabbits; Thiamine; Thiamine Pyrophosphate; Transketolase

1985
Comparison of the effects of some thiamine analogues upon thiamine transport across the blood-brain barrier of the rat.
    The Journal of physiology, 1985, Volume: 369

    Topics: Amprolium; Animals; Biological Transport; Blood-Brain Barrier; Brain; Female; Kinetics; Male; Oxythiamine; Pyrithiamine; Rats; Rats, Inbred Strains; Thiamine

1985
Some properties of the thiamine uptake system in isolated rat hepatocytes.
    Biochimica et biophysica acta, 1984, Nov-21, Volume: 778, Issue:1

    Topics: 2,4-Dinitrophenol; Animals; Biological Transport; Biological Transport, Active; Dinitrophenols; Kinetics; Liver; Male; Ouabain; Pyrithiamine; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains; Thiamin Pyrophosphokinase; Thiamine; Thiamine Pyrophosphate

1984
Dual system of intestinal thiamine transport in humans.
    The Journal of laboratory and clinical medicine, 1982, Volume: 99, Issue:5

    Topics: Biological Transport, Active; Carbon Radioisotopes; Duodenum; Ethylmaleimide; Humans; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Ion Channels; Pyrithiamine; Thiamine

1982
Inhibition of neuronal sodium and potassium ion activated adenosinetriphosphatase by pyrithiamin.
    Biochemistry, 1983, Apr-26, Volume: 22, Issue:9

    Topics: Animals; Cerebral Cortex; Kinetics; Male; Mitochondria; Pyridinium Compounds; Pyrithiamine; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase; Synaptic Membranes; Synaptosomes; Thiamine

1983
Reversal of pyrithiamine-induced growth inhibition of Saccharomyces cerevisiae by oxythiamine.
    Experientia, 1984, Jun-15, Volume: 40, Issue:6

    Topics: Oxythiamine; Pyridinium Compounds; Pyrithiamine; Saccharomyces cerevisiae; Thiamine; Thiazoles

1984
Thiamin antagonists and the release of acetylcholine and norepinephrine from brain slices.
    Biochemical pharmacology, 1984, Jul-15, Volume: 33, Issue:14

    Topics: Acetylcholine; Animals; Brain; Electric Stimulation; In Vitro Techniques; Male; Mice; Norepinephrine; Oxythiamine; Pyrithiamine; Rats; Rats, Inbred Strains; Thiamine

1984
Metabolic and histological reversibility of thiamine deficiency.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1983, Volume: 3, Issue:4

    Topics: Animals; Autoradiography; Body Weight; Brain; Diet; Glucose; Male; Pyrithiamine; Rats; Rats, Inbred Strains; Thiamine; Thiamine Deficiency; Time Factors

1983
Low energy levels in thiamine-deficient encephalopathy.
    Journal of neuropathology and experimental neurology, 1984, Volume: 43, Issue:3

    Topics: Animals; Behavior, Animal; Brain; Brain Diseases; Disease Models, Animal; Energy Metabolism; Male; Microscopy, Electron; Pyrithiamine; Rats; Rats, Inbred Strains; Thiamine; Thiamine Deficiency

1984
Inhibition of thiamine transport in baker's yeast by methylene blue.
    Experientia, 1980, Oct-15, Volume: 36, Issue:10

    Topics: Biological Transport; Kinetics; Methylene Blue; Pyrithiamine; Saccharomyces cerevisiae; Thiamine

1980
Effects of treatment with thiamin antagonists, oxythiamin and pyrithiamin and of thiamin excess of the levels and distribution of thiamin in rat tissues.
    Journal of nutritional science and vitaminology, 1982, Volume: 28, Issue:3

    Topics: Animals; Brain; Dose-Response Relationship, Drug; Liver; Male; Myocardium; Oxythiamine; Pyridinium Compounds; Pyrithiamine; Rats; Rats, Inbred Strains; Thiamine; Thiazoles

1982
Thiamine deficiency in the cat leads to severe learning deficits and to widespread neuroanatomical damage.
    Experimental brain research, 1982, Volume: 48, Issue:2

    Topics: Animals; Brain; Cats; Discrimination Learning; Female; Male; Mental Recall; Motor Activity; Pyrithiamine; Seizures; Thiamine; Thiamine Deficiency

1982
[Effect of pyrithiamine on rat sciatic nerve. (I) Morphological changes during the early stage of thiamine deficiency (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1980, Volume: 76, Issue:7

    Topics: Animals; Diet; Male; Pyridinium Compounds; Pyrithiamine; Rats; Sciatic Nerve; Thiamine; Thiamine Deficiency

1980
[An experimental study of pyrithiamine-induced encephalopathy in the rat. I. Clinical observation and the determination of the concentrations of thiamine in the brain and the blood (author's transl)].
    Rinsho shinkeigaku = Clinical neurology, 1981, Volume: 21, Issue:9

    Topics: Animals; Brain Chemistry; Brain Diseases; Male; Pyridinium Compounds; Pyrithiamine; Rats; Rats, Inbred Strains; Thiamine

1981
[Effect of oxythiamine and pyrithiamine on thiamine levels in the blood, liver and urine of rats (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1981, Volume: 78, Issue:6

    Topics: Animals; Liver; Male; Oxythiamine; Pyridinium Compounds; Pyrithiamine; Rats; Rats, Inbred Strains; Thiamine; Thiamine Deficiency; Thiazoles

1981
Effects of thiamin deprivation and antagonism on voluntary ethanol intake in rats.
    The Journal of nutrition, 1980, Volume: 110, Issue:5

    Topics: Acetaldehyde; Alcohol Drinking; Animals; Anorexia; Brain; Dopamine; Energy Intake; Male; Norepinephrine; Oxythiamine; Pyrithiamine; Rats; Thiamine; Thiamine Deficiency

1980
Thiamine and cholinergic transmission in the electric organ of Torpedo. II. Effects of exogenous thiamine and analogues on acetylcholine release.
    Journal of neurochemistry, 1980, Volume: 35, Issue:6

    Topics: Acetates; Acetylcholine; Animals; Biological Transport; Choline; Electric Organ; Electric Stimulation; Fishes; Kinetics; Oxythiamine; Pyrithiamine; Thiamine; Thiamine Pyrophosphate

1980
Extracellular glutamate is increased in thalamus during thiamine deficiency-induced lesions and is blocked by MK-801.
    Journal of neurochemistry, 1993, Volume: 61, Issue:6

    Topics: Amino Acids; Animals; Dizocilpine Maleate; Extracellular Space; Hippocampus; Male; Microdialysis; Pyrithiamine; Rats; Rats, Sprague-Dawley; Reference Values; Seizures; Thalamus; Thiamine; Thiamine Deficiency; Time Factors

1993
Amiloride toxicity in the fission yeast Schizosaccharomyces pombe is released by thiamine and mutations in the thiamine-repressible gene car1.
    Gene, 1996, May-24, Volume: 171, Issue:1

    Topics: Amiloride; Antimetabolites; Arginase; Drug Resistance, Microbial; Fungal Proteins; Gene Expression Regulation, Fungal; Genes, Fungal; Genes, Regulator; Membrane Proteins; Membrane Transport Proteins; Mutation; Pyrimidines; Pyrithiamine; RNA, Fungal; RNA, Messenger; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Thiamine; Thiazoles

1996
Pyrithiamine-induced thiamine deficiency impairs object recognition in rats.
    Behavioral neuroscience, 1995, Volume: 109, Issue:6

    Topics: Animals; Appetitive Behavior; Brain Mapping; Discrimination Learning; Male; Mental Recall; Pattern Recognition, Visual; Pyrithiamine; Rats; Retention, Psychology; Thalamus; Thiamine

1995
Identification and characterization of the thiamine transporter gene of Saccharomyces cerevisiae.
    Gene, 1997, Oct-15, Volume: 199, Issue:1-2

    Topics: Acid Phosphatase; Amino Acid Sequence; Biological Transport; Carrier Proteins; Cloning, Molecular; Drug Resistance, Microbial; Gene Expression Regulation, Fungal; Genes, Fungal; Genetic Complementation Test; Membrane Transport Proteins; Molecular Sequence Data; Pyrithiamine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Analysis, DNA; Thiamine

1997
Pyrithiamine resistance gene (ptrA) of Aspergillus oryzae: cloning, characterization and application as a dominant selectable marker for transformation.
    Bioscience, biotechnology, and biochemistry, 2000, Volume: 64, Issue:7

    Topics: Amino Acid Sequence; Antifungal Agents; Aspergillus oryzae; Base Sequence; Biomarkers; Cloning, Molecular; DNA, Fungal; Drug Resistance, Microbial; Fungal Proteins; Genes, Fungal; Microbial Sensitivity Tests; Molecular Sequence Data; Mutagenesis; Phenotype; Pyrithiamine; Sequence Analysis, DNA; Sequence Analysis, Protein; Sequence Homology, Amino Acid; Thiamine; Transcription, Genetic; Transformation, Genetic

2000
The use of thiamine and thiamine antagonists to investigate the etiology of early mortality syndrome in lake trout (Salvelinus namaycush).
    Aquatic toxicology (Amsterdam, Netherlands), 2001, Volume: 52, Issue:3-4

    Topics: Animals; Female; Fish Diseases; Fresh Water; Great Lakes Region; Male; Oxythiamine; Pyrithiamine; Thiamin Pyrophosphokinase; Thiamine; Thiamine Pyrophosphate; Trout

2001
Mechanism of thiamine uptake by human jejunal brush-border membrane vesicles.
    American journal of physiology. Cell physiology, 2001, Volume: 281, Issue:3

    Topics: Adenosine Triphosphate; Adult; Amiloride; Amprolium; Biological Transport; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Intestinal Mucosa; Jejunum; Kinetics; Membrane Potentials; Microvilli; Osmolar Concentration; Potassium; Pyrithiamine; Sodium; Temperature; Thiamine; Time Factors; Valinomycin

2001
Thiamin regulates agglutination and zygote formation in Schizosaccharomyces pombe.
    Current genetics, 1990, Volume: 17, Issue:3

    Topics: Culture Media; Dose-Response Relationship, Drug; Oxythiamine; Pyrithiamine; Reproduction; Schizosaccharomyces; Thiamine

1990
Neuropathological study of the role of mast cells and histamine-positive neurons in selective vulnerability of the thalamus and inferior colliculus in thiamine-deficient encephalopathy.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2003, Volume: 23, Issue:1

    Topics: Animals; Antimetabolites; Blood-Brain Barrier; Brain Diseases, Metabolic; Histamine; Immunohistochemistry; Inferior Colliculi; Male; Mast Cells; Models, Animal; Neurons; Pyrithiamine; Rats; Rats, Sprague-Dawley; Thalamus; Thiamine; Thiamine Deficiency

2003
Thiamine deficiency results in downregulation of the GLAST glutamate transporter in cultured astrocytes.
    Glia, 2003, Volume: 43, Issue:2

    Topics: Acid Anhydride Hydrolases; alpha-Tocopherol; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Astrocytes; Cell Size; Cells, Cultured; D-Aspartic Acid; Drug Interactions; Enzyme Inhibitors; Glutathione; Immunoblotting; Ketoglutarate Dehydrogenase Complex; Leucine; Pyrithiamine; Pyruvate Dehydrogenase Complex; Rats; Sodium-Potassium-Exchanging ATPase; Thiamine; Thiamine Deficiency; Time Factors; Transketolase; Tritium

2003
Metabolic effects of neopyrithiamine and the aneurin contents in the tissues of the rat.
    Experientia, 1954, Mar-15, Volume: 10, Issue:3

    Topics: Animals; Pyrithiamine; Rats; Thiamine

1954
Effects of oxythiamine and neopyrithiamine on phosphorylation of thiamine by thiamine phosphorylase from rat intestine.
    Biochimica et biophysica acta, 1954, Volume: 15, Issue:1

    Topics: Animals; Biochemical Phenomena; Glycogen Phosphorylase, Muscle Form; Intestines; Oxythiamine; Phosphorylases; Phosphorylation; Pyrithiamine; Rats; Thiamine

1954
[Demonstration of a new action of thiamine by the use of pyrithiamine].
    Bulletin de la Societe de chimie biologique, 1954, Volume: 36, Issue:9

    Topics: Pyrithiamine; Thiamine

1954
Thiamine deficiency after feeding pyrithiamine.
    Biochimica et biophysica acta, 1956, Volume: 19, Issue:1

    Topics: Humans; Pyridines; Pyrithiamine; Thiamine; Thiamine Deficiency; Vitamin B Deficiency

1956
[Effect of pyrithiamine on pigeons].
    Archivio italiano di scienze farmacologiche, 1956, Volume: 6, Issue:3

    Topics: Animals; Biological Phenomena; Columbidae; Nervous System; Physiological Phenomena; Pyrithiamine; Thiamine

1956
[Energy consumption, respiratory quotient and intestinal absorption in rats treated with neopyrithiamine].
    Bollettino della Societa italiana di biologia sperimentale, 1956, Volume: 32, Issue:9

    Topics: Animals; Biological Phenomena; Carbohydrate Metabolism; Glucose; Intestinal Absorption; Intestines; Pyrithiamine; Rats; Thiamine

1956
[Various properties of pyrithiamine, a vitamin B1 antagonist].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1956, Volume: 150, Issue:10

    Topics: Musculoskeletal Physiological Phenomena; Pyrithiamine; Thiamine

1956
[Neopyrithiamine-thiamine antagonism in relation to the vitamin action and pharmacological action of thiamine].
    Internationale Zeitschrift fur Vitaminforschung. Beiheft, 1957, Volume: 27, Issue:3

    Topics: Hostility; Pyrithiamine; Thiamine; Vitamins

1957
Influence of pyrithiamine and oxythiamine on the respiratory quotient, heat production and intestinal absorption of glucose, in the rat.
    Internationale Zeitschrift fur Vitaminforschung. Beiheft, 1957, Volume: 27, Issue:4

    Topics: Animals; Body Temperature; Cell Respiration; Glucose; Intestinal Absorption; Intestines; Oxythiamine; Pyrithiamine; Rats; Respiration; Thermogenesis; Thiamine

1957
The effect of administration of thiamine analogues (oxythiamine and pyrithiamine) on rat erythrocyte metabolism.
    The Journal of biological chemistry, 1957, Volume: 229, Issue:2

    Topics: Animals; Erythrocytes; Oxythiamine; Pharmaceutical Preparations; Pyrithiamine; Rats; Thiamine

1957
The mode of action of pyrithiamine as an inductor of thiamine deficiency.
    Biochimica et biophysica acta, 1958, Volume: 29, Issue:2

    Topics: Pyrithiamine; Thiamine; Thiamine Deficiency

1958
[Vitamin B1 deficiency induced by dietary means and by vitamin antagonists (neopyrithiamine and oxythiamine) in rodents].
    Internationale Zeitschrift fur Vitaminforschung. Beiheft, 1958, Volume: 28, Issue:3

    Topics: Diet; Oxythiamine; Pyrithiamine; Thiamine; Thiamine Deficiency; Vitamin B Deficiency; Vitamins

1958
Changes in tissue free aminoacids in thiamine-deficient or pyrithiamine-treated rats.
    Acta vitaminologica, 1958, Volume: 12, Issue:4

    Topics: Amino Acids; Animals; Biochemical Phenomena; Pyrithiamine; Rats; Thiamine; Thiamine Deficiency; Vitamin B Deficiency

1958
Cocarboxylase content of tissues of mice treated with pyrithiamine or oxythiamine.
    Internationale Zeitschrift fur Vitaminforschung. Beiheft, 1958, Volume: 29, Issue:1-2

    Topics: Animals; Mice; Oxythiamine; Pyrithiamine; Thiamine; Thiamine Pyrophosphate

1958
Studies on the toxicity of pyrithiamine.
    The Journal of the Egyptian Medical Association, 1960, Volume: 43

    Topics: Pyrithiamine; Thiamine

1960
[Carbohydrate metabolism of a fungus (Phycomyces blakesleeanus) in dependence on culture conditions. The influence of carbon sources, vitamin B1 and 2 and their antagonists (pyrithiamine and oxythiamine)].
    Archiv fur Mikrobiologie, 1959, Volume: 33

    Topics: Carbohydrate Metabolism; Carbohydrates; Carbon; Fungi; Oxythiamine; Phycomyces; Pyrithiamine; Riboflavin; Thiamine

1959
[Behavior of the adrenal in B1 avitaminosis due to neopyrithiamine].
    Bollettino della Societa italiana di biologia sperimentale, 1960, Mar-31, Volume: 36

    Topics: Adrenal Glands; Avitaminosis; Pyrithiamine; Thiamine; Thiamine Deficiency; Vitamin B Deficiency

1960
A study of urinary lactic acid levels in humans. I. Influence of thiamine and pyrithiamine.
    The Journal of vitaminology, 1960, Mar-10, Volume: 6

    Topics: Body Fluids; Humans; Lactates; Lactic Acid; Pyrithiamine; Thiamine

1960
Simultaneous determination of thiamine and pyrithiamine.
    Analytical biochemistry, 1962, Volume: 3

    Topics: Pyrithiamine; Thiamine

1962
Pyrithiamine adaptation of Staphylococcus aureus. I. Adaptation and carbohydrate utilization.
    Journal of bacteriology, 1962, Volume: 83

    Topics: Acclimatization; Citric Acid Cycle; Depressive Disorder, Major; Glucose; India; Pyrithiamine; Pyruvates; Staphylococcus; Staphylococcus aureus; Thiamine

1962
A striking difference in the thiamine-sparing action of fat on deficiencies produced by oxythiamine and pyrithiamine.
    The Journal of nutrition, 1962, Volume: 78, Issue:3

    Topics: Fats; Glycerol; Humans; Oxythiamine; Pyrithiamine; Thiamine; Thiamine Deficiency

1962
Separation and determination of thiamine and pyrithiamine in biological materials by chromatography on polyethylene powder.
    Analytical biochemistry, 1963, Volume: 5

    Topics: Chromatography; Polyethylene; Polyethylenes; Pyrithiamine; Thiamine

1963
EFFECT OF WATER SOLUBLE VITAMINS AND THEIR ANALOGUES ON GROWTH OF CANDIDA ALBICANS. II. VITAMIN B12, THIAMINE, OXYTHIAMINE, NEOPYRITHIAMINE, SUBSTITUTED PYRIMIDINES AND THIAZOLES.
    Mycopathologia et mycologia applicata, 1963, Dec-30, Volume: 21

    Topics: Antimetabolites; Biotin; Candida; Candida albicans; Culture Media; Metabolism; Oxythiamine; Pharmacology; Pyrimidines; Pyrithiamine; Research; Thiamine; Thiazoles; Vitamin B 12; Vitamin B Complex; Vitamins

1963
[PHOSPHATASE ACTIVITY OF SOME RAT TISSUES IN ALIMENTARY AVITAMINOSIS B1 AND AFTER TREATMENT WITH PYRITHIAMINE].
    Internationale Zeitschrift fur Vitaminforschung. International journal of vitamin research. Journal international de vitaminologie, 1963, Volume: 33

    Topics: Brain; Liver; Metabolism; Muscles; Pharmacology; Phosphoric Monoester Hydrolases; Pyrithiamine; Rats; Research; Thiamine; Thiamine Deficiency; Transferases

1963
[THE ANTAGONISM BETWEEN THIAMINE-PYRITHIAMINE IN ISOLATED ROOT CULTURES, WITH SPECIAL REFERENCE TO THE UPTAKE OF VITAMINS AND INHIBITORS].
    Internationale Zeitschrift fur Vitaminforschung. International journal of vitamin research. Journal international de vitaminologie, 1964, Volume: 34

    Topics: Antimetabolites; Culture Media; Metabolism; Plant Growth Regulators; Pyrithiamine; Research; Thiamine; Tissue Extracts; Vitamin A; Vitamin K; Vitamins

1964
AMPROLIUM. 8. COMPARISON WITH OXYTHIAMINE AND PYRITHIAMINE AS ANTAGONISTS OF THIAMINE IN THE CHICK.
    Poultry science, 1965, Volume: 44

    Topics: Amprolium; Animals; Antimetabolites; Biological Assay; Chickens; Meat; Oxythiamine; Poultry; Pyrithiamine; Research; Thiamine; Toxicology

1965
Studies on thiamine analogues. IV. Neopyrithiamine and oxyneopyrithiamine; a comparison of their effects in vivo and in vitro.
    The Journal of biological chemistry, 1955, Volume: 213, Issue:2

    Topics: Humans; In Vitro Techniques; Organic Chemicals; Pyrithiamine; Thiamine

1955
[Antivagal cardiac effect of thiamine and some of its derivatives (neopyrithiamine and hydroxthiamine)].
    Bollettino della Societa italiana di biologia sperimentale, 1962, May-31, Volume: 38

    Topics: Heart; Humans; Pyrithiamine; Thiamine; Vagus Nerve

1962
[Microbiological determination of some B-group vitamins. V. Titration of thiamine (vitamin B-1) using an inhibiting analog (pyrithiamine)].
    Rendiconti - Istituto superiore di sanita, 1962, Volume: 25

    Topics: Bacillus subtilis; Inorganic Chemicals; Organic Chemicals; Pyrithiamine; Thiamine; Vitamin A; Vitamin K; Vitamins

1962
The uptake of pyrithiamine by cerebral tissue.
    Experientia, 1961, Dec-15, Volume: 17

    Topics: Pyrithiamine; Thiamine

1961
Thiamine-regulated gene expression of Aspergillus oryzae thiA requires splicing of the intron containing a riboswitch-like domain in the 5'-UTR.
    FEBS letters, 2003, Dec-18, Volume: 555, Issue:3

    Topics: 5' Untranslated Regions; Aspergillus oryzae; Base Sequence; Drug Resistance, Microbial; Fungal Proteins; Gene Expression Regulation, Fungal; Genes, Fungal; Genes, Reporter; Glucuronidase; Introns; Molecular Sequence Data; Nucleotides; Promoter Regions, Genetic; Pyrithiamine; Recombinant Proteins; RNA Splicing; Sequence Alignment; Sequence Homology, Nucleic Acid; Thiamine

2003
Age-related vulnerability to diencephalic amnesia produced by thiamine deficiency: the role of time of insult.
    Behavioural brain research, 2004, Jan-05, Volume: 148, Issue:1-2

    Topics: Aging; Amnesia; Animals; Antimetabolites; Behavior, Animal; Body Weight; Brain Mapping; Cell Count; Cerebral Ventricles; Choline O-Acetyltransferase; Diet; Discrimination Learning; Disease Models, Animal; Immunohistochemistry; Korsakoff Syndrome; Male; Maze Learning; Memory, Short-Term; Prosencephalon; Pyrithiamine; Rats; Rats, Inbred F344; Spatial Behavior; Thiamine; Thiamine Deficiency; Time Factors

2004
Three thiamine analogues differently alter thiamine transport and metabolism in nervous tissue: an in vivo kinetic study using rats.
    Metabolic brain disease, 2003, Volume: 18, Issue:4

    Topics: Amprolium; Animals; Biological Transport; Body Weight; Carbon Radioisotopes; Kinetics; Male; Nerve Tissue; Oxythiamine; Phosphorylation; Pyrithiamine; Rats; Rats, Wistar; Thiamine; Thiamine Monophosphate; Thiamine Pyrophosphate; Tissue Distribution

2003
Primary cultures of rat astrocytes respond to thiamine deficiency-induced swelling by downregulating aquaporin-4 levels.
    Neuroscience letters, 2004, Aug-19, Volume: 366, Issue:3

    Topics: 3-O-Methylglucose; Animals; Animals, Newborn; Aquaporin 4; Aquaporins; Astrocytes; Blotting, Western; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Down-Regulation; Edema; Pyrithiamine; Rats; Rats, Sprague-Dawley; Thiamine; Thiamine Deficiency; Time Factors

2004
Neopyrithiamine and the thiaminase of fish tissues.
    The Journal of biological chemistry, 1949, Volume: 181, Issue:1

    Topics: Animals; Enzymes; Fishes; Hydrolases; Pyrithiamine; Thiamine

1949
Thiamine pyrophosphate riboswitches are targets for the antimicrobial compound pyrithiamine.
    Chemistry & biology, 2005, Volume: 12, Issue:12

    Topics: Anti-Infective Agents; Bacillus; Models, Biological; Molecular Structure; Nucleic Acid Conformation; Protein Structure, Tertiary; Pyrithiamine; RNA, Bacterial; Thiamine; Thiamine Pyrophosphate

2005
Development and resolution of brain lesions caused by pyrithiamine- and dietary-induced thiamine deficiency and alcohol exposure in the alcohol-preferring rat: a longitudinal magnetic resonance imaging and spectroscopy study.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:5

    Topics: Alcohol-Induced Disorders, Nervous System; Alcoholism; Animals; Antimetabolites; Biomarkers; Brain; Central Nervous System Depressants; Disease Models, Animal; Ethanol; Korsakoff Syndrome; Longitudinal Studies; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Nerve Degeneration; Pyrithiamine; Rats; Rats, Wistar; Survival Rate; Thiamine; Thiamine Deficiency

2007
Thiamine deficiency caused by thiamine antagonists triggers upregulation of apoptosis inducing factor gene expression and leads to caspase 3-mediated apoptosis in neuronally differentiated rat PC-12 cells.
    Acta biochimica Polonica, 2007, Volume: 54, Issue:2

    Topics: Active Transport, Cell Nucleus; Amprolium; Animals; Annexin A5; Apoptosis; Apoptosis Inducing Factor; Caspase 3; Cell Differentiation; Cell Membrane; Nerve Growth Factor; Neurons; Oxythiamine; PC12 Cells; Protein Binding; Pyrithiamine; Rats; Thiamine; Thiamine Deficiency; Up-Regulation

2007
Antithiamine Effect of Oxythiamine and Neopyrithiamine. A Comparative Study.
    Science (New York, N.Y.), 1949, Aug-12, Volume: 110, Issue:2850

    Topics: Humans; Oxythiamine; Pyrithiamine; Thiamine

1949
Involvement of thiaminase II encoded by the THI20 gene in thiamin salvage of Saccharomyces cerevisiae.
    FEMS yeast research, 2008, Volume: 8, Issue:2

    Topics: Gene Deletion; Hydrolases; Oxythiamine; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Phosphotransferases (Phosphate Group Acceptor); Pyrimidines; Pyrithiamine; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thiamine

2008
Thiamine deficiency increases β-secretase activity and accumulation of β-amyloid peptides.
    Neurobiology of aging, 2011, Volume: 32, Issue:1

    Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Analysis of Variance; Animals; Antioxidants; Aspartic Acid Endopeptidases; Brain; Cell Death; Cell Line, Tumor; Chromans; Disease Models, Animal; Gene Expression Regulation; Humans; Male; Mice; Mice, Inbred C57BL; Neuroblastoma; Peptide Fragments; Pyrithiamine; Reactive Oxygen Species; Thiamine; Thiamine Deficiency; Time Factors

2011
Thiamine deficiency induces massive cell death in the olfactory bulbs of mice.
    Journal of neuropathology and experimental neurology, 2013, Volume: 72, Issue:12

    Topics: Animals; Antimetabolites; Calcium-Binding Proteins; Caspase 3; Cell Death; Disease Models, Animal; DNA, Single-Stranded; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred DBA; Microfilament Proteins; Microglia; N-Methylaspartate; Neurons; Olfactory Bulb; Pyrithiamine; Thiamine; Thiamine Deficiency

2013
Identification of vitamin B1 metabolism as a tumor-specific radiosensitizing pathway using a high-throughput colony formation screen.
    Oncotarget, 2015, Mar-20, Volume: 6, Issue:8

    Topics: Cell Line, Tumor; Colony-Forming Units Assay; DNA Damage; HCT116 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Neoplasms; Pyrithiamine; Radiation Tolerance; Radiation-Sensitizing Agents; Thiamin Pyrophosphokinase; Thiamine; Transfection

2015
A Pivotal Role for Thiamine Deficiency in the Expression of Neuroinflammation Markers in Models of Alcohol-Related Brain Damage.
    Alcoholism, clinical and experimental research, 2019, Volume: 43, Issue:3

    Topics: Animals; Biomarkers; Brain; Ethanol; Frontal Lobe; Hippocampus; Inflammation Mediators; Male; Pyrithiamine; Rats; Thalamus; Thiamine; Thiamine Deficiency; Time Factors; Transcriptional Activation

2019
Thiamin transport in Helicobacter pylori lacking the de novo synthesis of thiamin.
    Microbiology (Reading, England), 2019, Volume: 165, Issue:2

    Topics: Bacterial Proteins; Biological Transport; Escherichia coli; Helicobacter pylori; Membrane Transport Proteins; Mutation; Operon; Pyrimidines; Pyrithiamine; Recombinant Proteins; Thiamin Pyrophosphokinase; Thiamine

2019
Protocatechuic Acid Prevents Some of the Memory-Related Behavioural and Neurotransmitter Changes in a Pyrithiamine-Induced Thiamine Deficiency Model of Wernicke-Korsakoff Syndrome in Rats.
    Nutrients, 2023, Jan-26, Volume: 15, Issue:3

    Topics: Animals; Korsakoff Syndrome; Neurotransmitter Agents; Pyrithiamine; Rats; Thiamine; Thiamine Deficiency

2023