Compounds > pyrindamycin a
Page last updated: 2024-09-04

pyrindamycin a and pyrroles

pyrindamycin a has been researched along with pyrroles in 9 studies

*Pyrroles: Azoles of one NITROGEN and two double bonds that have aromatic chemical properties. [MeSH]

*Pyrroles: Azoles of one NITROGEN and two double bonds that have aromatic chemical properties. [MeSH]

Compound Research Comparison

Studies
(pyrindamycin a)		Trials
(pyrindamycin a)		Recent Studies (post-2010)
(pyrindamycin a)		Studies
(pyrroles)		Trials
(pyrroles)		Recent Studies (post-2010) (pyrroles)
90026,1292,81512,100

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19903 (33.33)18.7374
1990's2 (22.22)18.2507
2000's4 (44.44)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Inouye, S; Ishii, S; Kariya, Y; Kondo, S; Nagasawa, M; Yamamoto, H1
Kodama, Y; Kondo, S; Nakazawa, T; Ohba, K; Sasaki, T; Sezaki, M; Shomura, T; Takeuchi, Y; Watabe, H; Yamamoto, H1
Ichimura, M; Iida, T; Muroi, K; Sano, H; Takahashi, K; Yasuzawa, T1
Ichimura, M; Mihara, A; Nakano, H; Ogawa, T; Takahashi, I; Takahashi, K1
Amishiro, N; Gomi, K; Kobayashi, E; Nagamura, S; Okamoto, A; Saito, H1
Amishiro, N; Gomi, K; Kobayashi, E; Nagamura, S; Okabe, M; Okamoto, A; Saito, H1
Searcey, M1
Bowen, JP; Handl, HL; Hartley, JA; Howard, TT; Hudson, SJ; Kiakos, K; Lee, M; Lingerfelt, BM; McNulty, L; Price, CA; Purnell, BL; Scott, AE; Summerville, K; Townes, HM1
Hartley, JA; Hudson, S; Kiakos, K; Lee, M; Lingerfelt, B; Purnell, B; Scott, A; Summerville, K; Townes, H1

Reviews

1 review(s) available for pyrindamycin a and pyrroles

ArticleYear
Duocarmycins--natures prodrugs?
    Current pharmaceutical design, 2002, Volume: 8, Issue:15

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Cell Survival; DNA; Drug Stability; Duocarmycins; Indoles; Leucomycins; Leukemia L1210; Prodrugs; Pyrroles; Pyrrolidinones; Structure-Activity Relationship; Tumor Cells, Cultured

2002

Other Studies

8 other study(ies) available for pyrindamycin a and pyrroles

ArticleYear
Antitumor activity of pyrindamycins A and B.
    The Journal of antibiotics, 1989, Volume: 42, Issue:11

    Topics: Animals; Antibiotics, Antineoplastic; DNA, Neoplasm; Duocarmycins; Humans; Indoles; Leukemia L1210; Leukemia P388; Male; Mice; Molecular Structure; Neoplasm Proteins; Pyrroles; RNA, Neoplasm; Specific Pathogen-Free Organisms; Tumor Cells, Cultured

1989
Pyrindamycins A and B, new antitumor antibiotics.
    The Journal of antibiotics, 1988, Volume: 41, Issue:10

    Topics: Animals; Antibiotics, Antineoplastic; Chemical Phenomena; Chemistry; Duocarmycins; Fermentation; Indoles; Leukemia P388; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Pyrroles; Streptomyces

1988
Structures of duocarmycins, novel antitumor antibiotics produced by Streptomyces sp.
    Chemical & pharmaceutical bulletin, 1988, Volume: 36, Issue:9

    Topics: Antibiotics, Antineoplastic; Duocarmycins; Indoles; Molecular Conformation; Pyrroles; Pyrrolidinones; Streptomyces

1988
Interconversion and stability of duocarmycins, a new family of antitumor antibiotics: correlation to their cytotoxic and antimicrobial activities in vitro.
    Oncology research, 1993, Volume: 5, Issue:4-5

    Topics: 3T3 Cells; Animals; Antibiotics, Antineoplastic; Cell Division; Cell Line, Transformed; Drug Stability; Duocarmycins; Hydrogen-Ion Concentration; In Vitro Techniques; Indoles; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Pyrroles; Pyrrolidinones; Temperature

1993
Synthesis and antitumor activity of duocarmycin derivatives: a-ring pyrrole compounds bearing 5-membered heteroarylacryloyl groups.
    Chemical & pharmaceutical bulletin, 1999, Volume: 47, Issue:10

    Topics: Acrylates; Animals; Antineoplastic Agents; Blood Cells; Combinatorial Chemistry Techniques; DNA; Duocarmycins; HeLa Cells; Humans; Indoles; Mice; Models, Chemical; Pyrroles; Pyrrolidinones; Sarcoma 180; Structure-Activity Relationship

1999
Synthesis and antitumor activity of duocarmycin derivatives: A-ring pyrrole compounds bearing beta-(5',6',7'-trimethoxy-2'-indolyl)acryloyl group.
    Bioorganic & medicinal chemistry, 2000, Volume: 8, Issue:7

    Topics: Animals; Antibiotics, Antineoplastic; Cell Division; Duocarmycins; HeLa Cells; Humans; Indoles; Inhibitory Concentration 50; Leukocyte Count; Male; Mice; Neoplasms, Experimental; Platelet Count; Pyrroles; Pyrrolidinones; Time Factors; Transplantation, Heterologous; Tumor Cells, Cultured

2000
Novel furano analogues of duocarmycin C1 and C2: design, synthesis, and biological evaluation of seco-iso-cyclopropylfurano[2,3-e]indoline (seco-iso-CFI) and seco-cyclopropyltetrahydrofurano[2,3-f]quinoline (seco-CFQ) analogues.
    Bioorganic & medicinal chemistry, 2002, Volume: 10, Issue:9

    Topics: Animals; Antineoplastic Agents, Alkylating; Binding Sites; Bone Marrow Cells; Cell Cycle; Cell Division; DNA; DNA Adducts; Drug Design; Drug Screening Assays, Antitumor; Duocarmycins; Furans; Hematopoietic Stem Cells; Indoles; Mice; Models, Molecular; Pyrroles; Quinolines; Structure-Activity Relationship

2002
Novel (S)-(-)- and R-(+)-seco-iso-cyclopropylfurano[e]indoline-5,6,7-trimethoxyindole-2-carboxamide (iso-CFI) analogs of duocarmycin C2: synthesis and biological evaluation.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2006, Volume: 2, Issue:2

    Topics: Animals; Antineoplastic Agents, Alkylating; Base Sequence; Cell Proliferation; DNA; Drug Screening Assays, Antitumor; Duocarmycins; Heterocyclic Compounds, 3-Ring; Indoles; Leukemia L1210; Melanoma, Experimental; Mice; Models, Chemical; Pyrroles; Stereoisomerism; Tumor Cells, Cultured

2006