pyrimidinones has been researched along with titanium-isopropoxide* in 1 studies
1 other study(ies) available for pyrimidinones and titanium-isopropoxide
Article | Year |
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Titanium(IV) isopropoxide mediated synthesis of pyrimidin-4-ones.
A novel, one-step method for the synthesis of tri- and tetrasubstituted pyrimidin-4-ones is reported. This method involves a titanium(IV)-mediated cyclization involving two sequential condensations of primary and beta-ketoamides. The reaction is operationally facile, readily scalable, and offers rapid entry into differentially substituted pyrimidin-4-one scaffolds. The high functional group compatibility allows for substantial diversification in the products generated from this transformation. Topics: Catalysis; Crystallography, X-Ray; Models, Molecular; Molecular Structure; Organometallic Compounds; Pyrimidinones; Stereoisomerism | 2010 |