pyrimidinones has been researched along with ethyl-acetoacetate* in 2 studies
1 review(s) available for pyrimidinones and ethyl-acetoacetate
Article | Year |
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Recent progress in asymmetric Biginelli reaction.
The Biginelli reaction, which involves the interaction of ethyl acetoacetate, urea, and an appropriate aryl aldehyde, was first discovered by Pietro Biginelli about 120 years ago. The Biginelli products (3,4-dihydropyrimidin-2(1H)-ones) are interesting materials due to their significant pharmacological and structural profiles. In the last decades, the asymmetric synthesis as a powerful tool has an effective impact on the Biginelli products and has increased their potencies and applications as drugs. Having the importance of this subject in mind, in this review we wish to present the recent rapid progress of asymmetric Biginelli reaction. Topics: Acetoacetates; Aldehydes; Catalysis; Pyrimidinones; Stereoisomerism; Urea | 2013 |
1 other study(ies) available for pyrimidinones and ethyl-acetoacetate
Article | Year |
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Lanthanide triflate catalyzed Biginelli reaction. one-pot synthesis of dihydropyrimidinones under solvent-free conditions.
Topics: Acetoacetates; Benzaldehydes; Catalysis; Indicators and Reagents; Metals, Rare Earth; Models, Molecular; Molecular Conformation; Molecular Structure; Pyrimidinones; Urea; Ytterbium | 2000 |