pyrimidinones and cupric-bromide

pyrimidinones has been researched along with cupric-bromide* in 1 studies

Other Studies

1 other study(ies) available for pyrimidinones and cupric-bromide

Article	Year
One-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones using CuBr2 as catalyst. Preparative biochemistry & biotechnology, 2006, Volume: 36, Issue:4 A simple, efficient procedure and improved conditions have been found to carry out the Biginelli reaction for the synthesis of 3,4-dihydropyrimidin-2(1H)-one derivatives. This synthesis was performed using CuBr2 as the catalyst in ethanol solution. The optimum conditions were as follows: the molar ratio of aldehyde to alpha,beta-diketone to urea or thiourea is 1:1:1:0.5, the molar ratio of catalyst to aldehyde is 25%, and the reaction time is 4 h. Under the above conditions, the highest yield of dihydropyrimidinones was up to 95%. Compared with the classical Biginelli reaction conditions, this new method has the advantage of excellent yields and short reaction times. Topics: Bromides; Catalysis; Copper; Ethanol; Pyrimidinones	2006

Article

Year

One-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones using CuBr2 as catalyst.

Preparative biochemistry & biotechnology, 2006, Volume: 36, Issue:4

A simple, efficient procedure and improved conditions have been found to carry out the Biginelli reaction for the synthesis of 3,4-dihydropyrimidin-2(1H)-one derivatives. This synthesis was performed using CuBr2 as the catalyst in ethanol solution. The optimum conditions were as follows: the molar ratio of aldehyde to alpha,beta-diketone to urea or thiourea is 1:1:1:0.5, the molar ratio of catalyst to aldehyde is 25%, and the reaction time is 4 h. Under the above conditions, the highest yield of dihydropyrimidinones was up to 95%. Compared with the classical Biginelli reaction conditions, this new method has the advantage of excellent yields and short reaction times.

Topics: Bromides; Catalysis; Copper; Ethanol; Pyrimidinones

2006