pyrimidinones and carbene

pyrimidinones has been researched along with carbene* in 1 studies

Other Studies

1 other study(ies) available for pyrimidinones and carbene

ArticleYear
Regio- and stereoselective synthesis of benzothiazolo-pyrimidinones via an NHC-catalyzed Mannich/lactamization domino reaction.
    Chemical communications (Cambridge, England), 2015, Jan-25, Volume: 51, Issue:7

    An NHC-catalyzed regio- and stereoselective Mannich/lactamization domino reaction of N-(benzothiazolyl)imines with α-chloroaldehydes has been developed. This new protocol provides a facile approach for the asymmetric synthesis of benzothiazolo-pyrimidinones and a pyrrolo[1,2-a]indolone in moderate to good yields (34-78%) and excellent stereoselectivities (87-99% ee, up to >20 : 1 d.r.).

    Topics: Catalysis; Imines; Lactams; Methane; Models, Molecular; Molecular Conformation; Pyrimidinones; Stereoisomerism; Substrate Specificity; Thiazoles

2015