pyrimidinones has been researched along with benzaldehyde* in 3 studies
3 other study(ies) available for pyrimidinones and benzaldehyde
| Article | Year |
|---|---|
Multicomponent Synthesis and Evaluation of New 1,2,3-Triazole Derivatives of Dihydropyrimidinones as Acidic Corrosion Inhibitors for Steel.
An efficient one-pot synthesis of 1,2,3-triazole derivatives of dihydropyrimidinones has been developed using two multicomponent reactions. The aldehyde-1,2,3-triazoles were obtained in good yields from in situ-generated organic azides and O-propargylbenzaldehyde. The target heterocycles were synthesized through the Biginelli reaction in which the aldehyde-1,2,3-triazoles reacted with ethyl acetoacetate and urea in the presence of Ce(OTf)₃ as the catalyst. The corrosion inhibition of steel grade API 5 L X52 in 1 M HCl by the synthesized compounds was investigated using the electrochemical impedance spectroscopy technique. The measurements revealed that these heterocycles are promising candidates to inhibit acidic corrosion of steel. Topics: Azides; Benzaldehydes; Catalysis; Corrosion; Pyrimidinones; Steel; Triazoles; Urea | 2016 |
Studies on the synthesis and biological activitiy of 6-ethyl-4-aryl-5-methoxycarbonyl-3,4-dihydropyrimidin-2(1H)-ones.
6-Ethyl-4-aryl-5-methoxycarbonyl-3,4-dihydropyrimidin-2(1H)-one derivatives (1-10) were synthesized by condensing urea with methyl 3-oxopentanoate and aromatic aldehydes in absol. ethanol using HCl as a catalyst according to the Biginelli reaction. The structures of the compounds were confirmed by spectroscopic and elemental analysis. The calcium channel blocker activities of the compounds were determined by the tests performed on isolated rat ileum and lamb carotid artery. On the isolated rat ileum, compound 2 was found to be more effective at 10(-5) mol/L concentration than nicardipine (CAS 55985-32-5). On the lamb carotid artery compounds 5, 6 and 4, 5, 6 were significantly active at 10(-6) mol/L and 10(-5) mol/L concentrations, respectively. Topics: Aldehydes; Animals; Benzaldehydes; Calcium Channel Blockers; Carotid Arteries; Crystallization; Female; Ileum; In Vitro Techniques; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Pyrimidinones; Rats; Sheep; Urea | 2007 |
Lanthanide triflate catalyzed Biginelli reaction. one-pot synthesis of dihydropyrimidinones under solvent-free conditions.
Topics: Acetoacetates; Benzaldehydes; Catalysis; Indicators and Reagents; Metals, Rare Earth; Models, Molecular; Molecular Conformation; Molecular Structure; Pyrimidinones; Urea; Ytterbium | 2000 |