pyrimidinones and barium-chloride

pyrimidinones has been researched along with barium-chloride* in 1 studies

Other Studies

1 other study(ies) available for pyrimidinones and barium-chloride

Article	Year
Synthesis, structural elucidation and pharmacological properties of some 5-acetyl-3,4-dihydro-6-methyl-4-(substituted phenyl)-2(1H) -pyrimidinones. Farmaco (Societa chimica italiana : 1989), 1999, Jun-30, Volume: 54, Issue:6 In this study, the synthesis of some new 5-acetyl-3,4-dihydro-6-methyl-4-(substituted phenyl)-2(1H)-pyrimidinones has been reported. The compounds were prepared by the Biginelli reaction of acetylacetone with aromatic aldehydes and urea. The structures of the compounds were characterized by UV, IR, 1H NMR, 13C NRM, mass spectra and elementary analysis. The calcium antagonistic activity of these compounds was tested in vitro on rat ileum precontracted with 4 x 10(-3) M barium chloride. Topics: Animals; Barium Compounds; Calcium Channel Blockers; Chlorides; Ileum; In Vitro Techniques; Magnetic Resonance Spectroscopy; Mass Spectrometry; Muscle Relaxation; Pyrimidinones; Rats; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet	1999

Article

Year

Synthesis, structural elucidation and pharmacological properties of some 5-acetyl-3,4-dihydro-6-methyl-4-(substituted phenyl)-2(1H) -pyrimidinones.

Farmaco (Societa chimica italiana : 1989), 1999, Jun-30, Volume: 54, Issue:6

In this study, the synthesis of some new 5-acetyl-3,4-dihydro-6-methyl-4-(substituted phenyl)-2(1H)-pyrimidinones has been reported. The compounds were prepared by the Biginelli reaction of acetylacetone with aromatic aldehydes and urea. The structures of the compounds were characterized by UV, IR, 1H NMR, 13C NRM, mass spectra and elementary analysis. The calcium antagonistic activity of these compounds was tested in vitro on rat ileum precontracted with 4 x 10(-3) M barium chloride.

Topics: Animals; Barium Compounds; Calcium Channel Blockers; Chlorides; Ileum; In Vitro Techniques; Magnetic Resonance Spectroscopy; Mass Spectrometry; Muscle Relaxation; Pyrimidinones; Rats; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet

1999